41 results about "Reactive center" patented technology

The invention refers to a kind of new method of superfine inorganic solid particle's surface modification method. It includes the following steps: in the condition of certain temperature, mechanical milling, the protection of nitrogen gas and the existence of catalyzer, choose the superfine particle as the reaction core, pass through the polycondensation with the monomer of ABx or AxB and graft the super-ramus polymer onto the surface of superfine particle. The surface character of superfine particle modified by the super-ramus polymer grafting is changed greatly and can disperse well in all kind of matrixes of rosin and solvent. The method can finish the task in one step. The modified inorganic solid particle can be applied to macromolecule composites, electric bloching material, plastics, dope, latex, antibiotic material and other fields and has a promising industrial application.

A method for stereoselective chemical synthesis, includes the steps of: (A) reacting a nucleophile and a chiral or prochiral cyclic substrate, said substrate comprising a carbocycle or a heterocycle having a reactive center susceptiable to nucleophilic attack by the nucleophile, in the presence of a chiral non-racemic catalyst to produce a product mixture comprising a stereoisometrically enriched product wherein the product mixture further comprises a catalyst residue, at least a portion of the catalyst residue is in a first oxidation state, and the catalyst residue in the first oxidation state is active in catalyzing degradation of the stereoisomerically enriched product, and (B) chemically or electrochemically changing the oxidation state of the catalyst residue form the first oxidation state to a second oxidation state, wherein catalyst residue in the second oxidation state is less active in catalyzing degradation of the stereoisomerically enriched product than is catalyst residue in the first oxidation state. The method reduces erosion of the chiral purify of the stereoisomerically enriched product and reduces the chemical transformation to side products of the stereoisomerically enriched product and co-product(s).

A process for the modification of activated charcoal material for the use of super capacitor negative electrode, wherein a nanometer level lead phosphate or lead sulfate modification layer is first formed in the activated charcoal micropore, then the barium sulfate reactive center is redeposited. After modification, the capacity of the active compound is increased by about 67%, the electrochemical window is expanded by 150 mV, thus improving the weight ratio energy capacity of the assortment type super capacitor. íí

The invention relates to a modification method for forming an alpha-alumina carrier of a silver catalyst used for producing ethylene oxide through ethylene oxidation. The method has the beneficial effect of increasing the pore canal and specific surface area of the carrier by carrying out acid-alkali combined treatment on the formed alpha-alumina carrier. The silver catalyst prepared from and supported by the alpha-alumina carrier prepared by the method is beneficial to increase of reaction centers and diffusion of products. The modified alpha-alumina carrier shows good selectivity when applied to the reaction process of producing ethylene oxide through ethylene oxidation.

The present invention relates to a method to limit insect and/or mite damage in plants, by the use of mutant plant proteinase inhibitors. More specifically, it relates to the use of mutant serpins of which the reactive center loop has been replaced by an artificial sequence. Preferably, the mutant serpins use an Arabidopsis thaliana serpin-1 backbone, or a homologue thereof. The mutant serpins have a specificity other than the wild-type serpins, and by modulating the reactive loop center, specific inhibitors against specific insect and/or mite proteases can be developed. Those mutant serpins can be used to inhibit or limit insect and/or mite damage, such as the damage caused by insect feeding.

Recombinant plasminogen activator inhibitor-1 (PAI-1) isoforms which lack the reactive center loop and contain the complete heparin-binding domain or lack at least a portion of the heparin-binding domain are described. The rPAI-1 isoforms disclosed herein may be used to modulate angiogenesis through blocking release of VEGF from a VEGF-heparin complex. Furthermore, the rPAI-1 proteins may be used to inhibit cell proliferation and migration, induce apoptosis, and produce proteolytic fragments corresponding to angiostatin kringles 1-3 and kringles 1-4. A truncated proteolytic plasmin protein of 34 kDa is also provided.

The invention discloses a novel PET material and a preparation method thereof, a pellet and a fiber product. According to the invention, isocyanurate, a 5-chloro-2-methyl-4-isothiazolin-3-one derivative, chloroethanol, terephthalic acid and ethylene glycol are used as raw materials, so the defect that traditional PET fibers have single and insufficient performance is overcome; meanwhile, reactionsteps are simple, operation is easy, and the defect of single performance of the traditional PET fibers are is overcome by adjusting the structure of a polymer; due to the addition of isocyanurate, the reaction activity of -NH2 is high, -NH2 can serve as a reaction center, high nitrogen content is obtained, and outstanding effect on the flame retardance of the material is achieved; as the 5-chloro-2-methyl-4-isothiazolin-3-one derivative is added, broad-spectrum bactericidal and mildew-proof effects are obtained, and the flame-retardant effect of the material can be further improved due to theexistence of N in a five-membered ring; in addition, the existence of different substituent groups endows the molecular structure of the material with flexibility, so the wide popularization and application of the material are facilitated.

Mutants of the human PAI-1 protein are described which are inhibitors of neutrophil elastase or are inhibitors of vitronectin (Vn)-dependent cell migration. These mutants preferably comprise one or two amino acid substitutions in the reactive center loop of PAI-1, particularly at positions 331 and 346 of the mature protein. These mutants are notable in being resistant to inactivation by elastase, having high affinity for Vn, or both properties. These mutant proteins as pharmaceutical compositions are used to inhibit elastase in a subject, thereby treating a number of disorders associated with elastase activity, most notatably emphysema, ARDS, inflammatory lung injury and cystic fibrosis. The mutants which interact with Vn are used to inhibit cell migration in a subject, thereby treating diseases or conditions associated with undesired cell migration and proliferation, particularly of smooth muscle cells. Such conditions include atherosclerosis, post angioplasty restenosis, fibrosis associated with chronic inflammation or chemotherapy, tumor invasion and metastasis and conditions in which angiogenesis is pathogenic. Also disclosed are peptides of such mutant proteins, mutant-specific antibodies, nucleic acid molecules, particularly DNA, encoding the mutant protein and host cells transformed by such nucleic acids.

The invention relates to a preparation method and application of a Fenton-like catalyst, in particular to a preparation method and application of a sulfur-doped carbon skeleton coated octasulfide heptairon nanoparticle double-reaction-center Fenton-like catalyst. The invention aims to solve the problems of metal ion leaching, poor stability, easy agglomeration and narrow reaction pH range of the existing Fenton-like catalyst. The method comprises the following steps: firstly, preparing an MIL-101 (Fe) precursor, and then calcining and vulcanizing to obtain the sulfur-doped carbon skeleton coated octasulfide heptairon nanoparticle double-reaction-center Fenton-like catalyst. The invention discloses a sulfur-doped carbon skeleton coated heptairon octasulfide nanoparticle double-reaction-center Fenton-like catalyst which is used for degrading antibiotics. Under the neutral condition, the degradation rates of tetracycline hydrochloride, norfloxacin and amoxicillin within 40 min can reach 100%, 97.8% and 98.9% respectively, and after 5 times of circulation, the removal rate of amoxicillin can still be kept at 91.1%.

The invention discloses a vegetation total primary productivity inversion method and system based on chlorophyll fluorescence. The method comprises the following steps: A, performing inversion through an SCOPE model to obtain a relationship among fluorescence emission efficiency, a chlorophyll function reaction center opening ratio and a continuous heat dissipation rate; B, analyzing SCOPE model parameters by adopting global sensitivity analysis (GSA), and selecting decisive parameters as classification parameters of plant functional PFTs; C, acquiring ground monitoring data, chlorophyll fluorescence data, surface reflectance data and temperature data of the research area, and respectively calculating a temperature stress factor and a water stress factor; and D, constructing a chlorophyll fluorescence inversion GPP model and calculating the vegetation total primary productivity GPP. According to the method, the fluorescence emission efficiency LUEf is obtained through inversion of the SCOPE model, then the temperature stress factor and the water stress factor are obtained in combination with various data, then the chlorophyll fluorescence inversion GPP model is obtained through training, and the vegetation total primary productivity GPP is obtained through inversion.

The invention discloses a planar chiral double-reactive center ruthenium catalyst, synthesis and an application thereof. The planar chiral double-reactive center ruthenium catalyst provided by the invention not only is simple in synthesis, but also has double reactive centers, and can be used efficiently for asymmetric catalytic hydrogenation of beta-aminoketone compounds; and finally a conversion rate of 100% and an asymmetric induction effect of more than 99.9% can be achieved. The synthesis of the catalyst of the invention is simple in operation, and high in selectivity and yield, and has good atom economy and good industrial application prospects.