52results about How to "Long period of action" patented technology

The present invention relates to an intranasal pharmaceutical dosage form comprising a dosing unit comprising naloxone or a pharmaceutically acceptable salt thereof in an amount of equivalent to ≧0.5 mg naloxone HCl dissolved in an application fluid of a volume of ≦250 μl. Furthermore, the present invention relates to such an intranasal pharmaceutical dosage form for use in the treatment of opioid overdosing and / or at least one symptom thereof.

The invention discloses a method for treating persistent halogenated hydrocarbons in soil by a slow-release compound remediation agent. The method includes steps: pre-ploughing contaminated soil, directly spreading a certain quantity of the slow-release compound remediation agent into ploughed soil, harrowing to well mix, watering to keep certain moisture content, and covering the soil surface with a protecting layer to realize anaerobic reduction dehalogenation reaction, wherein spreading quantity of the remediation agent is 0.05-1.5% of the dry weight of the contaminated soil, the soil ploughing depth is 25-40cm, the soil moisture content is adjusted to 50-80% of maximum field moisture capacity after spreading of the remediation agent, and remediation treatment time is 30-350d. The remediation method takes advantages of great adsorption performance of black charcoal, efficient chemical reducibility of nano zero-valence metal and dissimilatory iron reduction dehalogenation performanceof functional microorganisms to achieve physical, chemical and biological synergistic remediation effects on persistent halogenated hydrocarbon contaminated soil and has advantages of long action period, structural stability, low cost, environmental friendliness and the like.

The invention discloses a drugcoated balloon controllable in drug metabolism and a preparation method of the drugcoated balloon, and relates to the technical field of drugcoated balloons. The drugcoated balloon is prepared through the steps of mixing a drug acceptor protein inhibitor with drugs, water and ethanol to obtain medicinal liquid, spraying the medicinal liquid onto the surface of the balloon back and forth through ultrasonic spraying equipment, and performing drying so as to obtain the drugcoated balloon. The drug acceptor protein inhibitor can also be replaced with a drug metabolismisoenzyme inhibitor, an inducer or a mixture of the drug acceptor protein inhibitor and a drug metabolism isoenzyme inhibitor for preparing the medicinal liquid, and through adjusting the addition quantity of the drug acceptor protein inhibitor and the compounding ratio of the drug acceptor protein inhibitor to drugs further, the drug metabolism period of the drugcoated balloon can be adjusted and controlled. The invention provides the drugcoated balloon controllable in drug metabolism and a simple and efficient preparation method of the drugcoated balloon controllable in drug metabolism, andthe prepared drugcoated balloon has the functions that metabolism can be effectively controllable without destroying the structure of an intima, at the initial stage of using the drugcoated balloon,drug metabolism can be generated to achieve the effect of drug treatment, and the effect period of the drugs can be prolonged through adjusting the formula.

A cowshed feces deodorant comprises bacillus licheniformis, bacillus subtilis, dried yeast, lactic acid bacteria and photosynthetic bacteria and is prepared from, by weight, 47% of a complex bacterialagent and 53% of corn flour serving as a carrier by proportional mixing for feces deodorization. The complex bacterial agent is prepared by mixing, by weight, 15% of bacillus licheniformis, 21% of bacillus subtilis, 17% of lactic acid bacteria, 27-32% of dried yeast and 12-18% of photosynthetic bacteria, wherein the effective viable count of bacillus licheniformis, bacillus subtilis and photosynthetic bacteria is larger than 200 million per gram. The optimal proportions of dried yeast and photosynthetic bacteria in the complex bacterial agent are 32% and 15% respectively. The bacillus licheniformis can be bacillus cereus, bacillus latersprorus and bacillus megatherium; the photosynthetic bacteria can be rhodopseudomonas palustris and rhodopseudomonas sulfidophila.

The invention discloses a solid slow-release scale inhibitor and a preparation method thereof, and belongs to the technical field of oilfield auxiliary agents. A purpose of the invention is to solve the problems of a certain corrosivity to wellbore, short action period, high cost and the like of the scale inhibitor. According to the method, a quadripolymer is subjected to blending modification with organic attapulgite to obtain a solid slow-release scale inhibitor capable of effectively inhibiting formation and deposition of wellbore scale in an oil extraction process, greatly reducing the regular scale removal period of a wellbore, reducing the oil extraction cost and ensuring the safe and stable operation of an oil well. According to the invention, organic nano-clay is applied to the solid slow-release scale inhibitor, so that the stability and the mechanical strength of the solid slow-release scale inhibitor can be effectively improved, and the action period of the solid slow-release scale inhibitor is effectively prolonged.

The invention belongs to the technical field of tertiary oil recovery and particularly relates to a method for extracting oil in single well steam stimulation by combining microorganisms and CO2 in the heavy oil well. The method comprises the following steps: (1) screening test oil wells; (2) screening microorganisms and nutrients thereof; (3) injecting the microorganisms and the nutrients thereof into the stratum of the test oil well; (4) injecting liquid CO2; (5) shutting the test oil well down; (6) opening the test oil well for production. The method disclosed by the invention has the advantage of wide application range and is simple in process implementation; oil well sand production and sleeve damage situations are avoided and the oil well utilization rate is high; the thickened oil viscosity can be greatly reduced, the oil-water interfacial tension is reduced, the stratum energy can be effectively replenished, the characteristics of long action period, remarkable enhanced production effect of oil, and the like are achieved, and therefore, the method is an economic and effective method for increasing the yield of the heavy oil well and can be widely applied to a single well steam stimulation technology of the heavy oil well.

The invention discloses extinguishment liquor used for preventing and extinguishing coal spontaneous combustion fire hazards. Water is used as a solvent, and the extinguishment liquor comprises, by weight percentage, 20%-26% of a surface active agent, 6%-12% of sodium alkyl sulfonate, 9%-15% of melamine compounded phosphate ester, 9%-15% of ammonium chloride and potassium carbonate compounded diammonium hydrogen phosphate, 1%-4% of carboxymethylcellulose or xanthan gum, 2%-5% of urea or sodium xylene sulfonate, 5%-8% of magnesium chloride, 7%-12% of sodium bicarbonate and the balance water, and the total amount is 100%. By means of the extinguishment liquor used for coal spontaneous combustion, the coal spontaneous combustion fire hazards can be quickly and effectively extinguished, quickcooling for removing heat in a high temperature zone is achieved, after-combustion is avoided, and the extinguishment liquor used for coal spontaneous combustion is efficienct, quick, environment-friendly, low in cost and easy and convenient to operate.

The invention discloses a carbonized bamboo board mattress and belongs to the field of furniture. The carbonized bamboo board mattress comprises a mattress support framework equipped with a base plate and a panel respectively at two side surfaces thereof; a cavity forms between the base plate and the panel and is provided with external Chinese herbal medicines beneficial for human body; the panel is made of carbonized bamboo board and provided with a plurality of apertures. Compared with a prior art, the apertures on the panel of the invention enable efficacy of Chinese herbal medicines to extend above the mattress without obstruction and effect on a human body, so the effects are direct and obvious. Besides, a purpose of average effect of the external Chinese herbal medicines during an action period is realized; and efficacy of drug absorbed by the carbonized bamboo board radiates slowly, so an effect period of the external Chinese herbal medicines is prolonged. In addition, the carbonized bamboo board can improve integral environment of a bedroom.

The invention discloses a solid slow-release scale inhibitor and a preparation method thereof, and belongs to the technical field of oilfield auxiliary agents. A purpose of the invention is to solve the problems of a certain corrosivity to wellbore, short action period, high cost and the like of the scale inhibitor. According to the method, a quadripolymer is subjected to blending modification with organic attapulgite to obtain a solid slow-release scale inhibitor capable of effectively inhibiting formation and deposition of wellbore scale in an oil extraction process, greatly reducing the regular scale removal period of a wellbore, reducing the oil extraction cost and ensuring the safe and stable operation of an oil well. According to the invention, organic nano-clay is applied to the solid slow-release scale inhibitor, so that the stability and the mechanical strength of the solid slow-release scale inhibitor can be effectively improved, and the action period of the solid slow-release scale inhibitor is effectively prolonged.

The invention provides an immune-enhancing antineoplastic collagen composition as well as a preparation method and an application thereof. The composition is characterized by consisting of antineoplastic factors, collagen, polysaccharide substances and active factors. The composition is applicable to, but not limited in, cells for treating breast cancer, colorectal cancer, ovarian cancer, pancreatic cancer, prostatic cancer, bladder cancer, melanoma, lung cancer, stomach cancer, liver cancer, head and neck squamous cell carcinoma, carcinoma of uterine cervix, renal cell carcinoma, thyroid cancer, acute myeloid leukemia, myeloma, esophageal squamous cancer, lymphoma and the like.

The invention discloses a method for treating persistent halogenated hydrocarbons in soil by a slow-release compound remediation agent. The method includes steps: pre-ploughing contaminated soil, directly spreading a certain quantity of the slow-release compound remediation agent into ploughed soil, harrowing to well mix, watering to keep certain moisture content, and covering the soil surface with a protecting layer to realize anaerobic reduction dehalogenation reaction, wherein spreading quantity of the remediation agent is 0.05-1.5% of the dry weight of the contaminated soil, the soil ploughing depth is 25-40cm, the soil moisture content is adjusted to 50-80% of maximum field moisture capacity after spreading of the remediation agent, and remediation treatment time is 30-350d. The remediation method takes advantages of great adsorption performance of black charcoal, efficient chemical reducibility of nano zero-valence metal and dissimilatory iron reduction dehalogenation performanceof functional microorganisms to achieve physical, chemical and biological synergistic remediation effects on persistent halogenated hydrocarbon contaminated soil and has advantages of long action period, structural stability, low cost, environmental friendliness and the like.

The invention provides an immunoenhanced composition, a preparation method and application. The composition is characterized by comprising collagens which are free of immunogenicity and can be degraded in vivo, polysaccharide substances and loose particles of active factors. The immunoenhanced composition applied to vaccination can intensity the immunoreactions of an antigen, and reduce side effects of inflammation, granuloma and abscess in the immunoreactions.

The invention discloses a sustained-release composite remediation agent for treating persistent halogenated hydrocarbon in groundwater and a preparation method thereof. The preparation method comprises the following steps: 1) preparing bacterial liquid saturated black carbon; 2) preparing a colloidal solution A containing locust bean gum and an organic carbon source; 3) preparing a colloidal suspension B containing locust bean gum, an organic carbon source, a nano-scale zero-valent metal and the bacterial liquid saturated black carbon; 4) carrying out a crosslinking reaction for 2-6h; and 5) carrying out a delayed crosslinking reaction for 2-6h to obtain a sustained-release composite remediation agent for treating persistent halogenated hydrocarbon in groundwater. The sustained-release composite remediation agent prepared by the method provided by the invention can utilize the good adsorption performance of black carbon, the high-efficiency chemical reducibility of the nano-scale zero-valent metal and the dissimilation iron reduction dehalogenation capability of functional microorganisms to achieve the physical, chemical and biological synergistic remediation effect of persistent halogenated hydrocarbon polluted groundwater, and has the advantages of long action period, stable structure, low cost, environmental friendliness and the like.