43results about How to "Realize joint use" patented technology

The invention relates to a multi-channel electrospray ion source used in the combination of a micro liquid phase separation system and mass spectrum, wherein 2 to 100 single-channel electrospray nozzle needles/nozzles are fixed on the inlet of the vacuum area of a mass spectrometer, and are distributed in a sector, thereby ensuring that the central axial lines of the tail ends of the single-channel electrospray nozzle needles/nozzles are crossed at the position of 0cm to 1cm away from the front end of the inlet of the vacuum area and are at an angle of 0 degree to 90 degrees to the axial line of the vacuum inlet. When high voltage is respectively applied on each electrospray nozzle needle/nozzle, electrospray ionization of multi-flow path liquid phase can be realized, thereby realizing the combination of a liquid phase separation system and mass spectrum. The ion source has the characteristics of simple structure, easy debugging operation, convenient mode switching, excellent stability and low maintenance cost, etc., and can be directly fixed on a mass spectrometer along with better commonality and practicability. In addition, through installing electrospray nozzle needles/nozzles of different modes, the invention can realize the combination of micro liquid phase separation systems of a plurality of modes and mass spectrum.

The invention relates to a matched structure of a cooling device of an intermediate frequency furnace for heating a steel bar and a steel ball quenching device and belongs to the technical field of quenching facilities of metal pieces. The cooling device of the intermediate frequency furnace for heating the steel bar comprises a liquid quenching medium conveying pipe, wherein a blowdown connector is matched and connected on the lower part at the left end of the liquid quenching medium conveying pipe, a liquid quenching medium introducing connector is matched and connected to the upper part at the right end of the liquid quenching medium conveying pipe, and a liquid quenching medium output pipe connector is arranged on the middle part; the liquid quenching medium output pipe connector is provided with a control valve, a left seal cover is arranged at the left end, a right seal cover is arranged at the right end, a cavity of the liquid quenching medium conveying pipe is provided with a heat exchange pipe, a left seal cover connector is arranged on one side, back on to the left seal cover cavity, of the left seal cover and a right cover connector is arranged on one side, back on to the right seal cover cavity, of the right seal cover; a cooling liquid circulating mechanism is connected between the left and right seal cover connectors, and the control valve is connected with one end of the liquid quenching medium output pipeline; and the steel ball quenching device comprises a quenching tank. The intermediate frequency furnace does not need to be cooled by using a cooling tower, so that the intermediate frequency furnace is durably clean, the cost is lowered, the electric consumption and liquid are saved, and the work stability is ensured.

The invention belongs to the technical field of biology, and discloses a cell preservation solution as well as a preparation method and application thereof. The cell preservation solution comprises alcohol, acid, buffer salt, an ionic strength maintaining agent, an antioxidant and proteolytic enzyme. According to the cell preservation solution, samples of multiple mucus and blood cells can be well treated, and the staining effect of thin-layer liquid-based cytology detection is improved; however, the proteolytic enzyme can influence the staining effect of reductive blue tissue cells, the influence of the proteolytic enzyme on the staining of the reductive blue tissue cells is reduced by adding the antioxidant, and meanwhile, the accuracy and the stability of immune cell chemical staining and reductive blue tissue cell staining are improved; and moreover, the cell preservation solution has no influence on the accuracy and stability of HPV detection after preserving a cell sample. The cell preservation solution can meet requirements of four screening methods including thin-layer liquid-based cytology detection, HPV detection, immunocytochemical staining and vat blue tissue cell staining at the same time.

The invention belongs to the technical field of microfluidic chips, and particularly relates to a device and a mass spectrometry for direct electrospray ionization of a sample on a microfluidic chip. The device at least comprises a three-dimensional operating platform for placing the microfluidic chip, an electrode for providing spray voltage, a pulsed high-voltage power supply, and a mass spectrum arranged beside an ionization device, wherein the electrode for providing the spray voltage is not directly contacted with liquid in the microfluidic chip. A spray needle is not required to be fabricated or connected on the microfluidic chip, or the original design of a chip microchannel is not required to be changed, and a solution sample in the chip microchannel can be directly ionized by utilizing charge and discharge processes of pulsed voltage, and then the mass spectrometry can be conducted. In addition, a high-voltage in the device is not directly contacted with a solution, and the original function of the microfluidic chip is not affected due to chemical reaction on the electrode. The device is simple and convenient to operate, and is suitable for direct ionization and the mass spectrometry of the sample on the microfluidic chip.

The invention discloses a quasi-in-situ normal-pressure reaction combination system, which comprises a tubular furnace, an imaging device and a vacuum pipeline, wherein the tubular furnace, the vacuumpipeline and the imaging device are sequentially communicated to form a closed sample transfer space, the tubular furnace comprises a quartz tube, a first vacuumizing device and a heating unit, the first vacuumizing device and the heating unit are respectively used for adjusting the pressure and the temperature in the quartz tube, and the vacuumizing range of the first vacuumizing device at leastcomprises the normal pressure and the high vacuum degree with the same magnitude as the vacuum pipeline; and the vacuum pipeline is used for transmitting the sample subjected to normal pressure treatment in the quartz tube to the imaging device at a higher vacuum degree for surface imaging. The sample can be transmitted to the imaging device from the tubular furnace through the ultrahigh vacuum pipeline to be subjected to surface imaging, analysis of an electronic structure and/or a geometric structure and the like on the surface of the sample is completed, different sample treatment environments can be met, the environment requirement for imaging resolution can be guaranteed, and the combination of sample treatment and structural imaging characterization is realized.

The application discloses a fire fighting water cannon. The fire fighting water cannon comprises a main pipeline, a spraying head, a first branch pipeline and a second branch pipeline; the main pipeline is provided with a first end and a second end; the spraying head is arranged at the first end; water mist spraying structures which are used for spraying out water mist and water column spraying structures which are used for spraying out water columns are arranged on the spraying head; the water mist and the water column can be sprayed out simultaneously; the first branch pipeline is connectedto the second end and can communicate with the main pipeline; the second branch pipeline is connected to the second end and can communicate with the main pipeline; and the second branch pipeline and the first branch pipeline are arranged in parallel. According to the fire fighting water cannon of the structure, the fire fighting effect is improved through combined use of column-mist, and the spraying distance of the water columns and/or water mist can be adjusted by changing water pressure, so that a fire fighting effect can be further improved; and therefore, the requirements on the emergencytreatment, such as safety, high-efficiency fire fighting/decontamination, in different places can be met better.

The invention belongs to the field of medicine and particularly relates to an intelligent and novel medicine composition having anti-hepatitis B virus activity and a preparation method thereof.The medicine composition contains an enteric magnesium isoglycyrrhizinate sheet core and further contains other types of anti-hepatitis B virus medicine.To be specific, further improvement is made on the basis of the prior art, a dissolution layer is further added outside an enteric magnesium isoglycyrrhizinate coating layer, and unexpectedly, the magnesium isoglycyrrhizinate medicine composition high in dissolution rate and good in bioavailablity is obtained.Furthermore, the dissolution layer is sequentially wrapped by a medicine containing layer and a protection layer, so that a compound preparation is formed, the compound preparation is convenient to take, and patient compliance is greatly improved.

The invention belongs to the field of active components, and relates to a method for screening biologically active components in a complex component with high throughput through a planar chromatographic component microarray. The method prepares a planar chromatography which integrally reflects the diversity and difference characteristics of a complex component into a planar chromatographic component microarray sample, and the sample can be taken to carry out a biological activity test and focused on a significant biological activity detection unit to carry out mass spectrometry; and the dependency relation between the biological activity intensity at an area having the significant biological activity detection unit and the biomass spectrometry excimer ion peak intensity of corresponding array units and chromatographic behavior coupling degrees of the two are taken as indications, so that biological activity components can be analyzed from the complex component with complex components and intervallic content. The method does not need to perform separation and purification on chemical components one by one in advance and complete analysis and detection, does not depend on a moleculardiversity compound library and is good in compatibility, high in flux and digitized, and samples can be amplified in parallel, so that screening efficiency can be greatly enhanced, and workloads andcosts can be reduced.

The invention discloses a multi-device combined three-dimensional atom probe sample universal interface device, which comprises a needle tip sample supporting table, a common sample table matching table and a sample switching part, the needle tip sample supporting table is arranged on the common sample table matching table, and the sample switching part is used for fixing the common sample table matching table. The device is used in combination with microscopic structure analysis instruments such as a scanning electron microscope, an EBSD-TKD, a transmission electron microscope, a focused ion beam, a three-dimensional atom probe and the like. According to the invention, transmission electron microscope analysis, scanning electron microscope analysis, focused ion beam analysis, EBSD or TKD analysis of a three-dimensional atom probe tip sample are realized by using a plurality of microscopic structures to analyze an original common sample table. The device is simple in structure, convenient to process and maintain and extremely low in cost, double inclination of the sample can be realized in the transmission electron microscope, the tip sample of the three-dimensional atom probe can be directly observed in different microscopic structure analysis instruments, and advantage complementation of various instruments and equipment is realized.

The invention discloses a system and a method for implementing gem identification based on Raman spectrum and optical coherence tomography (OCT). The system comprises a gem sample, a glass slide, a cassette, a mobile platform, a Raman spectrometer, an OCT, a data extraction and processing module and a display, wherein the cassette comprises two light holes. The method comprises the steps of firstly using OCT to acquire a no-load image via the light holes during no-load of the glass slide, and then separately using OCT and the Raman spectrometer to detect the sample on the glass slide, to acquire a sample spectrogram and an OCT image; using computer software to analyze the image to acquire boundary and distance information of the sample, completing the computation of a refractive index viaan optical path matching principle, and analyzing a Raman spectra to acquire a chemical property of the sample; and finally displaying a measurement result via the display. The system and method are simple in design, simple and convenient to operate, and achieve quick switching on measurement of the same sample; measurement and comprehensive analysis of multiple indexes such as physical property (optical refractive index) and chemical components of the irregular gem material are implemented; and meanwhile, the method achieves automation, digitization and intelligent measurement of optical refractive indexes of different faults of the gem.

The invention discloses a blast furnace ironmaking device with a high-leakproofness hearth. The blast furnace ironmaking device comprises a furnace foundation, a bottom plate, a furnace shell, a sealing plate, a first cooling device, a sealing device and a heat conducting isolation barrel, wherein a refractory brick layer and a concrete layer are sequentially horizontally arranged in a space formed by the sealing plate and the bottom plate from up to down; the first cooling device is arranged between the sealing plate and the upper surface of the refractory brick layer; the first cooling device comprises a first cooling pipe, a second cooling pipe and a plurality of heat conducting connecting plates which are in the shape of a mosquito-incense holder; the sealing device is arranged on theouter side wall of the bottom of the furnace shell; the sealing device comprises an integrally formed sealing barrel and a sealing round plate which is horizontally and fixedly connected to the upperend of the sealing barrel; two groups of drainage plates are vertically and fixedly connected between the heat conducting isolation barrel and the furnace shell; and two groups of heat conducting plates are vertically and fixedly connected between the heat conducting isolation barrel and the sealing barrel. According to the blast furnace ironmaking device, temperature of the hearth can be decreased, the hearth can be subjected to liquid seal, and leakproofness of the hearth is greatly improved.

A lower limb massage device comprises a foot massager and a leg massager. An opening for user feet to extend in is formed in the top of the foot massager and comprises a front side wall and a rear side wall. The leg massager comprises a connecting base and a massage part. Two opening grooves side by side are formed in the massage part. The massage part is fixed to the connecting base. The connecting base is rotationally fixed to the leg massager so that the leg massager can rotate relative to the foot massager. The connecting base protrudes outwards to form a cramp. The massage part is provided with a connecting groove. A cramp groove is formed in the position, corresponding to the cramp, of the connecting groove. The massage part is detachably fixed to the connecting base through the connecting groove. The lower limb massage device has the advantages that the leg massager can rotate relative to the foot massager so that the massage part can switch from a calf massage function to a shank front part massage function, the massage part can be detached and separated, can independently provide massage and can be used for massaging thighs and knees or used by other people.

The invention discloses a liquid chromatography-mass spectrometry detection method capable of directly analyzing a salt-containing sample based on electric arc thermal coupling, which comprises the following steps that 1) sample atomization is conducted, the spraying direction of a liquid phase spraying generation module is adjusted, the direction pointed by a nozzle is the tip of a metal heat source with a tip, after being separated by liquid chromatography, the sample enters a liquid path pipeline of the liquid phase spray generation module and flows out from a liquid path spray head, atomized gas is sprayed out from a gas path spray head 112 through a gas path pipeline, and the sample in the liquid path spray head is atomized into small liquid drops under the action of the atomized gas; and 2) ionization is conducted, the atomized droplets are sprayed on a metal heat source which is coupled with the electric arc and is provided with a tip, the metal heat source with the tip ionizes the droplets to generate gas phase ions, and then the gas phase ions enter mass spectrometry to realize efficient ionization analysis of the charged ions. The liquid chromatography combination is achieved, and the efficient separation characteristic of the liquid chromatography and the high salt tolerance characteristic of the AEAI are fused;.