The invention discloses an organic-inorganic base fertilizer for winter vegetable planting. The base fertilizer is prepared from the following components in parts by weight: horse manure, rice straw,mushroom dregs, biogas slurry, polyglutamic acid, biological bacteria, trace elements, biomass charcoal, selenium ore powder, silicon fertilizer, fused calcium-magnesium phosphate, potassium humate, and amino acid fertilizer. The base fertilizer provided by the invention uses animal waste, agricultural waste and the like as a base fertilizer substrate, and then adds biological bacteria, trace elements, inorganic fertilizers and the like, and mixes into biogas slurry. On the one hand, According to the base fertilizer provided by the invention, comprehensive nutrition is provided for the basic growth of crops, and on the other hand, soil structure can be improved, soil organic matter and fertility can be enhanced, soil temperature is risen, photosynthesis of vegetables is promoted, antifreeze and insect repellent ability is imprioved, and vegetable growth rate is effectively improved, moreover, animal manure and agricultural waste are recycled, and environment is protected.