92 results about "Chimonanthus nitens" patented technology

The invention relates to a preparation method of effective fractions of shining wintersweet leaf, a preparation method and a use of a preparation thereof, in particular to an application of the effective fractions of the shining wintersweet leaf and the preparation thereof in drugs used for preventing and treating respiratory system diseases as well as in anti-cold drugs, antimicrobial drugs, anti-inflammation drugs, antiviral drugs, antifungal drugs, etc. In the invention, the volatile effective fractions and non-volatile effective fractions are added to the crude drug of the shining wintersweet medicinal material with a weight ratio of the actual extraction amount of the shining wintersweet to the effective fractions being 1.0-2.6:0.5-3.5, thus the effective fractions of the shining wintersweet leaf are obtained. A preparation of the effective fractions of the shining wintersweet can be made into granules, soft capsules, capsules, drop pills, tablets, compound capsules, dispersible tablets, etc. In the invention, the preparation of the shining wintersweet is deeply developed, which ensures that the preparation is rich in active ingredients, has definite effective ingredients, obvious pharmacological action and significant improvement of drug action. Besides, the preparation has stable performance and controllable quality, is safe and reliable, has less dosage, and is favorable for transportation and storage of the medicine as well as for patients to take.

The invention belongs to the field of medicines and health products, and concretely relates to an application of Chimonanthus salicifolius total alkaloid extract and monomer compounds thereof in the preparation of medicines or health products for treating gastrointestinal tumor diseases. The Chimonanthus salicifolius total alkaloid extract and chimonanthine monomer compounds (1-4) are extracted and prepared from a Calycanthaceae Chimonanthus plant Chimonanthus salicifolius, and experiments prove that the Chimonanthus salicifolius total alkaloid extract can substantially inhibit proliferation of stomach cancer SGC-7901, colorectal carcinoma SW1116 and colorectal carcinoma HCT116 cells and induce cancer cell apoptosis, and the alkaloid monomer compounds have different inhibition effects on the stomach cancer SGC-7901, colorectal carcinoma SW1116 and colorectal carcinoma HCT116 cells. The Chimonanthus salicifolius extract and the monomer compounds thereof can be applied individually or together or be combined with a suitable excipient, can be processed through a routine method to prepare an oral or non-oral dosage form used for treatment or assisted treatment of gastrointestinal tumor diseases, and is especially suitable for being used to prepare medicines or health products for treating stomach cancer and colorectal carcinoma.

The invention provides a medicine for preventing and treating respiratory diseases, and its preparation method. The preparation method is characterized in that the method comprises the following steps: dissolving borneol and menthol in edible ethanol and edible acetate acid gracial, sequentially adding edible vinegar, edible propionic acid, edible acetic acid, medical hydrochloric acid, food-grade formic acid and water, uniformly stirring, uniformly mixing the obtained substance with a powdery mixture or a volatile oil mixture of Atractylodes lancea, mint, Leaf of Tasmanian Bluegum, Artemisia argyi, Folium Viticis Negundo, Herba Schizonepetae, Folium Perillae, leaf of Chimonanthus nitens Oliv., Cymbopogon distans, Herba Moslae, dahurian angelica root, Manchurian wildginger, ginger, dried orange peel, Wrinkled Gianthyssop, Ligusticum sinense and lavender, and filling the obtained material to a bottle to obtain the medicine.

The invention discloses food retention-removing and summer heat-relieving tea and a production method thereof, and relates to the technical field of health tea. The production method disclosed by the invention comprises the following steps: picking tea leaves, removing tea-green colour and withering, picking and treating chimonanthus nitens, treating ginger, treating brown sugar, uniformly mixing, rolling, fermenting, drying and extracting fragrance. According to the production method disclosed by the invention, nutritional ingredients in tea leaves, chimonanthus nitens, ginger and brown sugar are combined together by a scientific method, thus forming tea with food retention-removing and summer heat-relieving effects and with a high nutritional value.

The invention provides Chimonanthus nitens leaf concentrated pills and a preparation method thereof. The preparation method comprises the following steps of: by taking Chimonanthus nitens leaves as araw material; extracting Chimonanthus nitens leaf volatile oil by virtue of a microwave-assisted steam distillation method; concentrating and drying an alcohol extract into an extract; concentrating and drying a water extract into clear paste powder; drying dregs obtained by filtering; grinding and then screening to obtain fine dreg powder; forming pills from the fine dreg powder, the extract andthe clear paste powder by virtue of a molding method; drying at a low temperature, thereby obtaining pills; preparing the volatile oil into a beta-cyclodextrin inclusion compound; drying; grinding into powder; covering the pills, the fine dreg powder, the inclusion compound powder and a disintegrating agent; rounding; and polishing, thereby obtaining the concentrated pills. The Chimonanthus nitensleaf concentrated pills prepared by the invention are high in content of active ingredients of the Chimonanthus nitens leaf, high in bioavailability and high in active titer. According to the preparation method disclosed by the invention, on the basis of a traditional use manner of the Chimonanthus nitens leaves, all components of the Chimonanthus nitens leaves are used, so that the concentratedpills have the advantages of being high in medicinal material availability and capable of reducing resource waste, the administration compliance of patients can be improved, and the concentrated pillshave excellent market prospects.

The invention provides a traditional Chinese medicine composition for treating lung cancer radiotherapy complication. The traditional Chinese medicine composition is prepared from prepared rehmannia roots, asparagus cochinchinensis, radix paeoniae alba, platycodon grandiflorum, cordyceps sinensis, bulbus fritillariae cirrhosae, glabrous sarcandra herbs, eclipta, dogwood, folium eriobotryae, vines of multiflower knotweed, radix scrophulariae, honeysuckle, scutellaria baicalensis, liquorice, rhizoma polygonati, American ginseng, rice galingale herbs, talinum crassifolium, pinellia ternate, chimonanthus nitens and peacock tail. The traditional Chinese medicine composition has definite functions of resisting to lung cancer radiotherapy complication, whole-body centralization is considered, and immunity is enhanced, so that recurrence and metastasis of tumor are reduced and delayed, more superiority is achieved compared with traditional hormonotherapy, after the traditional Chinese medicine is adopted to treat lung cancer radiotherapy complication, the traditional Chinese medicine composition has great advantages, the curative effect is remarkable, the side effect is little, the life quality of a patient can be improved, and the traditional Chinese medicine composition is worthy of clinic application and popularization.

The invention discloses a traditional Chinese medicine composition for relieving late period symptoms of liver diseases, belonging to the field of traditional Chinese medicine compositions. The traditional Chinese medicine composition is used for relieving the symptoms such as tiredness, poor appetite, abdominal distension, insomnia, mental restlessness and uncomfortable liver occurring in the later period of the liver diseases, is prepared by combining salvia miltiorrhiza, radix bupleuri, hyptis suaveolens, dried body of ground beetle, Codonopsis lancifolia, prinsepia utilis royle, schisandra chinensis, liquorice, dried tangerine or orange peel, Poria cocos, donkey-hide gelatin, Platycodon grandiflorum, Chimonanthus nitens, rhizoma atractylodis and the root of kudzu vine, and has the effects of soothing the liver and moistening lung, clearing heat for detumescence and promoting appetite and inducing diuresis. When the product is matched with antiviral and antitumor medicines for the liver diseases, the living quality and physical conditions of patients suffering from late liver diseases can be effectively improved.

The invention discloses application of a chimonanthus plant in influenza virus resistance, and particularly relates to application of the chimonanthus plant and extracts thereof in preparation of medicines for resisting influenza virus and diseases caused by the influenza virus. The chimonanthus plant comprises chimonanthus salicifolius, Zhejiang wintersweet and chimonanthus nitens; and the extracts are extracted by water extraction, alcohol extraction, vapor distillation and supercritical extraction.

The invention relates to a medicament for treating lung cancer. The medicament is prepared from the following raw materials: zinnia elegans, gray vernonia, mangrove bark, six-eared blumea, pilea notate, sea-buckthorn, dracontomelon duperreanum, semen canavaliae, threeleaf loosestrife herb, phyllanthusreticulatus poir., chimonanthus nitens and trametes versicolor. The medicament is prepared from pure traditional Chinese medicines, the features that the natural medicines are small in toxicity and good in curative effect are maintained, and the lung cancer can be effectively treated.

The invention relates to a medicament for treating haemorrhoids. The medicament is prepared from the following active ingredients in parts by weight: 10 parts of daphne tangutica, 15 parts of adinandra mellettii, 15 parts of chimonanthus nitens, 20 parts of heliotropium indicum, 10 parts of korsakow monochoria, 10 parts of woodfordia fruticosa, 5 parts of myosoton aquaticum, 15 parts of rhododendron dauricum, 15 parts of pteris vittata, 10 parts of lespedeza cuneata, 15 parts of yellowflower toadlily herb and 10 parts of urena procumbens. The medicament for treating haemorrhoids takes natural medicaments, is rapid to take effect, good in curative effect and very applicable to treatment on haemorrhoids.

The invention provides a preparation method of Chinese medicinal oral liquid made of Chimonanthus nitens leaf for treating common cold. The preparation method comprises the following steps of: soaking sun-dried Chimonanthus nitens leaf in water, extracting by steam distillation to obtain volatile oil, and filtering to obtain medicinal liquid and residue; decocting the residue in water twice, and filtering to obtain medicinal liquid; mixing the medicinal liquids, concentrating into fluid extract; cooling, adding ethanol, stirring, standing, filtering, recovering ethanol, and concentrating to obtain fluid extract; and mixing the fluid extracts with the volatile oil, adding corrective, antiseptic, essence and water, mixing, refrigerating, filtering, bottling, and sterilizing. The inventive oral liquid has the advantages of high degree of dispersion, good stability, controllable quality, and good safety.

The invention discloses a medicinal liquor for treatment of rheumatic cold disease of joints. The medicinal liquor is prepared from the following medicinal materials by mass: 8-12g of cinnamon, 15-20g of radix aconiti kusnezoffii, 15-20g of Taxillus sutchuenensis, 22-28g of dried branches and leaves of Piper puberulum, 22-28g of sarcandra glabra, 55-65g of Androsace umbellate, 15-20g of Zanthoxylum nitidum, 4-6g of Alangium chinense, 12-15g of camphor tree root, 15-20g of root of Chimonanthus nitens, 15-20g of Chinese fevervine herb, 10-15g of herba epimedii, 10-15g of eucommia, 10-15g of Chinese wolfberry, 25-35g of Lysimachia christinae Hance, and 1-1.5kg of rice wine. The medicinal materials are soaked in 30-40deg rice wine for 10-15d. Through reasonable compatibility of the component medicinal herbs, the medicinal liquor has the efficacy of nourishing blood and expelling wind, dispelling cold and eliminating dampness, warming channels and dredging collaterals, can effectively treat or relieve rheumatic cold disease of joints, has an effective rate of 98%. 10 days form a course of treatment, and no other side effect exists during medication.

The invention provides a traditional Chinese medicinal preparation for preventing radiation side reactions of nasopharynx cancer chemoradiotherapy. The traditional Chinese medicinal comprises the following raw drugs: acanthopanax, dangshen, glossy privet fruit, rhizoma belamcandae, coix seed, caulis dendrobii, rhizoma coptidis, cordate houttuynia, rhizoma anemarrhenae, radix rubiae, bamboo shavings, herba agrimoniae, angelica, radix paeoniae rubra, chrysanthemum, rhizoma zedoariae, selaginella, pseudostellaria root, uncaria, Chinese yam, Chimonanthus nitens, indigofera tinctoria, meadow fescue, eleusine indica, conyza japonica, hypericum sampsonii hance, rhubarb, Chinese date, dodder, aleppo avens, sealwort, ternate buttercup root, loranthus parasiticus, cryptotaenia japonica and honeysuckle stem. The traditional Chinese medicinal preparation is good in the curative effect and free from toxic or side effects, can be used as auxiliary therapeutic drug for the nasopharynx cancer chemoradiotherapy synchronously and used with the chemoradiotherapy for a nasopharynx cancer patient, has great advantages of enhancing the curative effect of chemoradiotherapy, relieves the side reactions after the chemoradiotherapy and improving the quality of life, and meanwhile, displays a good prospect for comprehensive treatment of the malignant tumor.

A disclosed medicinal liquor comprises parthenocissus dalzielii, radix puerariae, rhizoma imperatae, radix astragali, radix angelicae dahuricae, millettia specisoa, zanthoxylum simulans root, fructus liquidambaris, ramulus mori, cassia twig, cortex eucommiae, endoconcha sepiae, ganoderma, hippocampus, syngnathus, hydrophis, starfish, semen coicis, clypeasteroida, musk, raw radix rehmanniae, rhizoma drynariae, rhizoma cibotii, herba epimedii, ground beetle, radix clematidis, mahonia bealei, pheretima, radix cyathulae, polygonum suffultum, radix angelicae pubescentis, caulis sargentodoxae, semen persicae, flos carthami, fructus lycii, caulis lonicerae, chimonanthus nitens, alangium chinense, radix paeoniae alba, radix paeoniae rubra, a traditional Chinese medicine named as Suoluo, fructus ligustri lucidi, a traditional Chinese medicine named as Yeqiaolian, radix salviae miltiorrhizae, cortex magnoliae officinalis, radix aconiti kusnezoffii, radix aconite, herba lycopodii and caulis spatholobi. The medicinal liquor has the effects of relaxing sinews and activating blood, soothing qi and relieving pain, tonifying kidney and nourishing bone, warming meridians and freeing vessels, and the like, and also has substantial treatment effects on lumbar disc herniation and bulge, hyperosteogeny, cervical spondylosis, cervical vertebra hyperosteogeny, limb numbness, arthralgia and the like.

The invention discloses chimonanthus nitens-containing tea and a preparation method thereof. According to the preparation method, adopted tea leaves are composed of chimonanthus nitens leaves and teatree leaves at a weight ratio of 1:4-5. The preparation method comprises the steps of picking, pretreatment, primary enzyme deactivation, secondary enzyme deactivation, rolling and drying. The chimonanthus nitens leaves and the tea tree leaves are reasonably proportioned by weight; according to the present invention, the tea leaves are prepared by using the scientific and reasonable preparation process, the sensory evaluation effect of the obtained tea is good, more antioxidant substances can be retained, especially the classified enzyme deactivating manner is used, and an enzymatic hydrolysate is sprayed during the secondary enzyme deactivation, such that the sensory score of the tea and the content of total polyphenols and flavonoids can be substantially improved, and the quality of thetea is substantially improved.

The invention discloses a novel alkaloid compound chimonin-2, 3-diketone separated from dry leaves of chimonanthus nitens, and the novel alkaloid compound chimonin-2, 3-diketone has the following structure: in vitro test research proves that the compound can inhibit replication of influenza A virus H1N1 and has good anti-influenza A virus H1N1 activity. The compound can be further researched and developed into anti-influenza virus drugs.

The invention discloses a traditional Chinese medicine composition for treating urticaria and a preparation method thereof. The traditional Chinese medicine composition is prepared by the following main raw materials in weight ratio: 10-16% of mother chrysanthemum, 10-16% of chimonanthus nitens, 9-13% of dandelion, 11-14% of red-spotted stonecrop, 10-15% of neroli, 9-15% of lindera angustifolia, 7-12% of radix clematidis, 10-14% of red notopodium, 7-14% of cockscomb, 6-10% of periostracum cicada, 11-15% of clerodendron cyrtophyllum turcz, 12-18% of fructus forsythiae, 9-14% of root of clerodendrum bungei, 6-12% of fructus kochiae, 7-11% of berchemia lineate, and 9-12% of eucalyptus robusta leaf. The traditional Chinese medicine composition has accurate treatment effect, and can enhance own immunity, keep dynamic balance of natural physiology performance of body, and recovering the skin self-maintenance function; the traditional Chinese medicine composition can treat both symptoms and root causes and is not easy to reoccur; besides, the traditional Chinese medicine composition avoids the toxic and side effects caused by taking oral Western medicine hormone and external medicinal extract for a long time.

The invention discloses a chimonanthus nitens leaf capsule and a preparation method thereof. The chimonanthus nitens leaf capsule is prepared from chimonanthus nitens leaves and starch, the chimonanthus nitens leaves are thoroughly washed, aired and then cut up, water is added for boiling, and volatile oil is extracted through a vapor distillation method; the water solution obtained after distillation is collected through an additionally prepared container, medicine dregs are decocted with water for extraction, filtrate obtained after filtering is mixed with the water solution obtained after distillation, and vacuum concentration is carried out till dry extract is formed; after the dry extract is smashed, the starch is added, the materials are mixed to be uniform, pelleting, drying and particle finishing are carried out, the volatile oil is sprayed, the materials are mixed to be uniform and contained in a capsule, and the capsule can be obtained. The capsule smells fragrant and tastes a little bitter, the total amount of quercetin and kaempferol contained in each capsule is not smaller than 50.0 micrograms, the effects of cooling and exterior syndrome relieving and heat and toxic material removing are achieved, and the capsule can be effectively used for treating wind-heat type common colds, fevers, aversion to cold, throat pain and other symptoms, and is good in treatment effect, simple in preparation process, wide in raw material source and low in cost.

The invention discloses an application of chimonanthus plant extracts in preparing medicines, and in particular relates to an application of chimonanthus plants and extracts thereof in preparing medicines for preventing/treating various diseases. The chimonanthus plants include chimonanthus salicifolius, chimonanthus zhejiangensis or chimonanthus nitens; and the extracts are obtained by aqueous extraction, alcohol extraction, steam distillation and supercritical extraction.

The invention relates to a traditional Chinese medicine for treating purulent oesophagitis. The traditional Chinese medicine is prepared from the following medicinal materials in parts by weight: 12 parts of ligusticum wallichii, 8 parts of christia constricta, 14 parts of paulownia, 10 parts of agapetes, 12 parts of capparis acutifolia, 10 parts of rhoeo discolor, 12 parts of eria graminifolia, 15 parts of the root of Chinese barberry, 14 parts of peganum harmala, 8 parts of favus of the scalp, 8 parts of thesium chinense, 10 parts of rhizoma smilacis chinensis, 10 parts of cynanchum auriculatum royle ex wight, 16 parts of gentiana sarcorrhiza ling et ma, 10 parts of schefflera delavayi, 10 parts of rhodiola rosea, 12 parts of calathodes, 12 parts of galium bungei, 12 parts of chimonanthus nitens, 12 parts of sibbaldia procumbens and 12 parts of membranaceous beautyleaf root. Clinical trial shows that the traditional Chinese medicine is capable of safely and effectively treating purulent oesophagitis.