The invention mainly relates to the technical field of textiles, and discloses an antibacterial mite-removing pillowcase. The antibacterial mite-removing pillowcase is prepared from cotton fibers, bamboo fibers, polyester fibers, seaweed fibers, polylactic acid fibers, pineapple leaf fibers and melia azedarach bark fibers; the pillowcase is soft, skin-friendly, washable, antibacterial and capableof absorbing moisture, preserving heat and removing mites, no pilling occurs, the antibacterial rate reaches 82.3%, and the mite removal rate reaches 85.6%; blending is conducted on the cotton fibers,the bamboo fibers and the polyester fibers to make the polyester fibers wrapped inside, and the strength and antibacterial performance of the pillowcase are improved; after the seaweed fibers and themelia azedarach bark fibers are blended, primary fibers are added to be wrapped inside, the antibacterial and mite-removing performance of the pillowcase is improved, the skin metabolism is promoted,the hair quality is improved, and the occurrence of hair loss and dandruff is reduced; after the polylactic acid fibers and the pineapple leaf fibers are blended, secondary fibers are added to be wrapped inside, the smoothness of the pillowcase is improved, long hair is prevented from being knotted, and meanwhile, the antibacterial and mite-removing performance and biological properties of the pillowcase can be improved.