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45results about How to "Avoid Active Effects" patented technology

Artificial blood vessel loaded with pseudo-ginseng medicines, and preparation method and application for artificial blood vessel

ActiveCN102784015AGood and sustained antithrombotic effectQuick releaseBlood vesselsForeign objectThrombus
The invention provides an artificial blood vessel loaded with pseudo-ginseng medicines, and a preparation method and application for the artificial blood vessel. The artificial blood vessel sequentially consists of an inner layer, a middle layer and an outer layer which are closely connected with one another; the outer layer consists of nondegradable polymer materials; the middle layer consists of degradable high polymer materials and pseudo-ginseng powder distributed on the surface and/or the inside of the middle layer; the inner layer consists of degradable natural biological materials and pseudo-ginseng powder distributed on the surface and/or the inside of the inner layer; the mass percent of the pseudo-ginseng powder in the inner layer is larger than 5%; the content of the pseudo-ginseng powder in the middle layer is higher than that of the pseudo-ginseng powder in the inner layer; the outer layer is a nondegradable layer and is mainly used for protecting and replacing a blood vessel for a long time; the middle layer is a long-acting antithrombosis layer, can degrade high polymers, and can slowly release medicines so as to realize a long-acting antithrombosis effect; and the inner layer is a quick degrading layer, when the blood vessel is punctured and injured by a foreign object, the pseudo-ginseng medicines wrapped in the blood vessel are directly exposed on a wound, blood is stopped quickly, and the artificial blood vessel is particularly suitable for application to products such as hematodialysis.
Owner:MEDPRIN REGENERATIVE MEDICAL TECH +1

Separation culture method of anaerobic bacteria

The invention discloses a separation culture method of anaerobic bacteria. The method comprises the following steps: preparing a culture medium; filling nitrogen before sterilizing the culture medium; carrying out enrichment culture of a strain; and carrying out separation culture on the strain, wherein the separation culture on the strain adopts a way of alternate inoculated culture by a liquid culture medium and a solid culture medium, and the liquid culture medium inoculates the solid culture medium by capillary glass tube puncture, a cylindrical anaerobic culture cavity with a smooth inoculating face is formed in the solid culture medium, and round holes formed on the surface of the solid culture medium are sealed after inoculation by adopting an unset culture medium so as to form a sealed anaerobic culture cavity, and the inner wall of the anaerobic culture cavity is a culture face of anaerobic bacteria. According to the method disclosed by the invention, the anaerobic culture cavity with the smooth inoculating face is formed in the solid culture medium to provide an anaerobic environment for culturing anaerobic bacteria, so that the use of anaerobic equipment is reduced, the separating process is simplified, the cost in the separating process is lowered, and the time of acquiring single strain is shortened.
Owner:CHINA PETROLEUM & CHEM CORP +1

Electrode separating typed dialyze device for treating heavy metal poisoning

The invention mainly relates to an electrode separating typed dialyze device for treating heavy metal poisoning. The electrode separating typed dialyze device comprises an impulse pump I, an electrochemistry dialyzing column, an ultrafiltration dialyzer, a bubble valve and an impulse pump II. The electrochemistry dialyzing column is divided into three rooms via a positive ion dialysis membrane and a negative ion dialysis membrane, and the three rooms includes a positive electrode room, a negative electrode room and a blood channel. The tops of the positive electrode room and the negative electrode room are respectively communicated with a positive electrode dialyzate groove and a negative electrode dialyzate groove, two ends of the blood channel are communicated with the impulse pump I and the ultrafiltration dialyzer, and the ultrafiltration dialyzer is divided into a dialyzate room and a blood room via a ultrafiltration membrane. Electrostatic field force is utilized to directly dissociate complex generated by heavy metal ion in heavy metal poisoning blood and blood albumin, so that heavy metal ion can be separated from the complex and concentrates to the negative electrode under the force of the electrostatic field to become heavy metal to depose on a battery lead plate, so that the purpose of blood purification and heavy metal nosotoxicosis treatment.
Owner:HENAN UNIV OF SCI & TECH

Method for recycling activated carbon after disposing of waste mercury catalyst

The present invention relates to the technical field of activated carbon recycling in disposing of a waste mercury catalyst, in particular to a method for recycling activated carbon after disposing of the waste mercury catalyst. The method comprises: adjusting waste residue containing activated carbon obtained after disposing of the waste mercury catalyst into seriflux by adding water; after precipitation and filtration of the seriflux, dissolving mercury-containing components and other impurities soluble in water in the filtrate; putting the filtrate into an absorption slot, and putting the precipitate into a distillation furnace to carry out high temperature treatment at a temperature of 850-900 DEG C after drying the precipitate; and subliming PVC after destruction of the PVC in the activated carbon, and emptying gaps of activated carbon, so as to improve the activity effect of the activated carbon. Compared with fresh activated carbon in terms of the activity effect, when disposing of an equal amount of colored wastewater, the dosage of the activated carbon is 0.05-0.07 times higher than the dosage of the fresh activated carbon; and discharge of mercury during the process of recycling and disposing the activated carbon is reduced, and the environmental pollution rate is reduced.
Owner:贵州蓝天固废处置有限公司

Up-converting NaYF4:Yb<3+>,Tm<3+>nanocrystal-hypocrellin complex preparation method and applications of the prepared complex in photosensitive therapy

InactiveCN104826111AAvoid the effects of the crystallization processEffective up-conversion luminous efficiencyEnergy modified materialsAntineoplastic agentsSolventIn vivo
The invention relates to an up-converting NaYF4:yb<3+>,Tm<3+>nanocrystal-hypocrellin complex preparation method, which comprises: synthesizing an up-converting NaYF4:yb<3+>,Tm<3+>nanocrystal with an excitation wavelength of 980 nm and an up-converting fluorescence wavelength of 470 nm by using a hydrothermal method, removing the surface modifier of the nano-crystal under an acid condition to obtain a nanocrystal aqueous solution, adding a hypocrellin solution, incubating, and removing the unadsorbed hypocrellin and the solvent through dialysis so as to obtain the nanocrystal-hypocrellin complex. With the method of the present invention, the hypocrellin is loaded on the up-converting nanocrystal surface to form the complex, such that the hypocrellin long wave sensitizing purpose is achieved, and the disadvantages of short excitation wavelength and shallow therapy light source tissue penetration depth of the hypocrellin are overcome so as to promote the application of the hypocrellin in treatment of solid tumors in vivo. The present invention further relates to applications of the complex prepared through the method in preparation of photosensitive therapy drugs.
Owner:NANJING NORMAL UNIVERSITY

Preparation method of lipidosome and method for producing lipidosome adjuvant

The invention relates to a preparation method of lipidosome and application of the lipidosome as a vaccine immunologic adjuvant. The invention provides a lipidosome preparation method. The preparationmethod comprises the following steps: (1) weighing hydrogenated soy phosphatidylcholine (HSPC), cholesterol (CHOL), 1,2-dioleoyloxytrimethylammonium chloride (DOTAP-Cl), and vitamin (VE), and mixinginto a mixture according to a weight ratio of (70 to 90): (0 to 30): (10 to 20): 0.5; (2) dissolving the mixture in step 1 in a chloroform/methanol solvent to obtain lipoid organic solution for standby use, wherein the chloroform/methanol solvent is prepared from chloroform, methanol and ultrapure water in a volume ratio of 24: 72: (4 to 5); and (3) weighing soluble powdery solid holder, placing in a 250ml round-bottom flask, adding the lipoid organic solution, uniformly stirring, placing on a rotary evaporator under a condition of icy/water bath constant-temperature, removing the organic solvent, wherein the weight of the solid holder is five times the weight of the mixture, and the solid holder is prepared from one or more of lactose, saccharose, mannitol and sodium chloride. The preparation method is simple in process, low in cost and suitable for the mass culture of lipidosome and applicable to the vaccine immunologic adjuvant.
Owner:上海络祥基因科技有限公司

Flexible fiber medicine box capable of intelligently releasing medicines, and preparation and application of flexible fiber medicine box

ActiveCN113940923AAvoid sudden releaseIntelligently change the amount releasedOrganic active ingredientsBio-packagingSpinningOrganosolv
The invention relates to a flexible fiber medicine box capable of intelligently releasing medicines, and preparation and application of the flexible fiber medicine box. The preparation process of the medicine box comprises the steps that firstly, a pore-foaming agent and a high-molecular polymer are sequentially added into an organic solvent, the pore-foaming agent and the high-molecular polymer are evenly mixed to serve as a spinning solution to carry out electrostatic spinning, and a nanofiber membrane is prepared; then, the nanofiber membrane is put into a Tris-hydrochloric acid buffer solution containing dopamine to be subjected to modification treatment, and the nanofiber membrane modified by polydopamine is obtained; then, the nanofiber membrane modified by the polydopamine is put in a mixed solution for grafting reaction to obtain a fiber membrane loaded with a switch; and finally, the fiber membrane loaded with the switch is cleaned and dried to obtain the flexible fiber medicine box. The medicine box comprises porous fibers, and PMAA is chemically grafted at holes on the porous fibers. The prepared medicine box is subjected to medicine carrying treatment, and then a medicine release test is performed: the medicine box does not suddenly release within the first 4-6 hours in an environment with the pH value of 7.0-7.4, and ta medicine release amount is gradually increased along with reduction of the pH value of the medicine release environment.
Owner:DONGHUA UNIV

Capsule essence and method for preparing capsule essence

The invention discloses capsule essence. According to the technical scheme, the capsule essence is characterized by comprising a double-layer capsule, the double-layer capsule comprises an active ingredient layer, an effective ingredient layer and a gel shell, the effective ingredient layer wraps the active ingredient layer, and the gel shell wraps the effective ingredient layer; at least one surfactant is contained before the active ingredient layer and the effective ingredient layer are in contact with each other so that a user can conveniently take out the essence in the essence applicationprocess, and hands are not likely to be injured. The invention further discloses a method for preparing the capsule essence. According to the method, active ingredients containing surfactants and effective ingredients containing polyelectrolyte are contained in a first liquid pump and a second liquid pump respectively, then double-layer liquid drops are formed at an outlet of a double-layer dropper connected with the first liquid pump and the second liquid pump through co-extrusion, and the double-layer liquid drops drip into a reaction container and react with a gelation solution in the reaction container to generate the gel shell. The method has the advantage of being simple and efficient in implementation.
Owner:北京婼薇乐护肤品有限公司

A bionic dual-drive device for reverse intestinal flora transplantation with magnets and wheat awns

ActiveCN110404153BRelieve painShorten intubation timeMedical devicesAnatomyCurative effect
A bionic dual-drive reverse intestinal flora transplantation device with magnet and wheat awn, including a pipeline body with open head and tail ends, a sliding jacket and an internal magnet are arranged at the head end of the pipeline body, and the internal magnet is arranged on the pipeline body The upper end of the sliding jacket is closed, wrapping the inner wall of the pipeline body and the outer surface of the magnet in the body. The outer wall of the sliding jacket is provided with an imitation wheat awn structure, and the inner wall and the tail of the outer wall of the sliding jacket are respectively connected with pull lines. The tail end of the main body is provided with Velcro, and the Velcro is distributed on the inner and outer walls of the pipeline body. The pulling wires are connected and fixed on the Velcro, and the side wall at the head end of the pipeline body is provided with a side hole. The present invention can obviously shorten the time of catheterization, and can inject the bacteria-containing liquid after inserting into a deeper part, so as to ensure the curative effect, eliminate the discomfort brought by the traditional oral intestinal flora transplantation to patients, and at the same time avoid gastric juice and other effects on the bacterial flora activity. Influence, to achieve the purpose of injecting the liquid containing the intestinal flora to be transplanted through the lower digestive tract.
Owner:崇好科技有限公司

Extraction method of rose-boot small molecular substance capable of resisting altitude reaction

The invention relates to an extraction method of rose-boot small molecular substances capable of resisting altitude reaction, which comprises the steps of high-pressure steaming, enzymatic hydrolysis, adsorption, filtration, concentration, drying and finished product packaging. The extraction method is characterized in that the extraction method specifically comprises the following steps of taking dried small block rose-boot raw materials and steaming the raw materials for one hour at constant temperature being 124DEG C and constant pressure being 0.14MPa; after disinfection by increasing temperature, decreasing the temperature to 53DEG C, adding 0.7% special enzymes for plant extraction and conducting enzymatic hydrolysis for 3.5 hours; adding 6% activated carbon for adsorption; primarily filtering statically placed solution through a filter, then filtering the solution by using a plate-frame protection filter and finally filtering the solution to a supernatant fluid storage tank; and conducting vacuum concentration at negative 0.05MPa and 80DEG C and detecting the baume degree during concentration. The extraction method of rose-boot small molecular substances capable of resisting altitude reaction has the advantages of simple process and high extraction rate, and is suitable for the extraction of rose-boot small molecular substances.
Owner:吴庆林

Artificial blood vessel loaded with pseudo-ginseng medicines, and preparation method and application for artificial blood vessel

ActiveCN102784015BGood and sustained antithrombotic effectQuick releaseBlood vesselsForeign objectThrombus
The invention provides an artificial blood vessel loaded with pseudo-ginseng medicines, and a preparation method and application for the artificial blood vessel. The artificial blood vessel sequentially consists of an inner layer, a middle layer and an outer layer which are closely connected with one another; the outer layer consists of nondegradable polymer materials; the middle layer consists of degradable high polymer materials and pseudo-ginseng powder distributed on the surface and / or the inside of the middle layer; the inner layer consists of degradable natural biological materials and pseudo-ginseng powder distributed on the surface and / or the inside of the inner layer; the mass percent of the pseudo-ginseng powder in the inner layer is larger than 5%; the content of the pseudo-ginseng powder in the middle layer is higher than that of the pseudo-ginseng powder in the inner layer; the outer layer is a nondegradable layer and is mainly used for protecting and replacing a blood vessel for a long time; the middle layer is a long-acting antithrombosis layer, can degrade high polymers, and can slowly release medicines so as to realize a long-acting antithrombosis effect; and the inner layer is a quick degrading layer, when the blood vessel is punctured and injured by a foreign object, the pseudo-ginseng medicines wrapped in the blood vessel are directly exposed on a wound, blood is stopped quickly, and the artificial blood vessel is particularly suitable for application to products such as hematodialysis.
Owner:MEDPRIN REGENERATIVE MEDICAL TECH +1

A method for isolating and culturing anaerobic bacteria

The invention discloses a separation culture method of anaerobic bacteria. The method comprises the following steps: preparing a culture medium; filling nitrogen before sterilizing the culture medium; carrying out enrichment culture of a strain; and carrying out separation culture on the strain, wherein the separation culture on the strain adopts a way of alternate inoculated culture by a liquid culture medium and a solid culture medium, and the liquid culture medium inoculates the solid culture medium by capillary glass tube puncture, a cylindrical anaerobic culture cavity with a smooth inoculating face is formed in the solid culture medium, and round holes formed on the surface of the solid culture medium are sealed after inoculation by adopting an unset culture medium so as to form a sealed anaerobic culture cavity, and the inner wall of the anaerobic culture cavity is a culture face of anaerobic bacteria. According to the method disclosed by the invention, the anaerobic culture cavity with the smooth inoculating face is formed in the solid culture medium to provide an anaerobic environment for culturing anaerobic bacteria, so that the use of anaerobic equipment is reduced, the separating process is simplified, the cost in the separating process is lowered, and the time of acquiring single strain is shortened.
Owner:CHINA PETROLEUM & CHEM CORP +1

Functional factor reinforced crunchy candy and processing method thereof

The invention discloses a functional factor reinforced crunchy candy and a processing method thereof. The processing method comprises the following steps: firstly, mixing 35 to 55 parts of isomaltose hypgather powder, 10 to 20 parts of erythritol powder, 10 to 20 parts of isomalt powder, and 25 to 35 parts of water and heating to a temperature of 70 to 90 DEG C to enable sugar to be molten; and then sugaring off, cooling, separating sugar semifinished products, preparing peanut butter rich in a garcinia mangostana L pericarp compound coating, crisping to make a core, whitening to prepare couverture and forming, wherein the peanut butter rich in the garcinia mangostana L pericarp compound coating is prepared by compounding a compound A, a compound B, a compound C and vitamin C which are separated from garcinia mangostana L pericarp according to a weight ratio of 1:(1-2):(1-2):(1-2) to form a garcinia mangostana L pericarp active material compound coating and adding the garcinia mangostana L pericarp active material compound coating into peanut butter. According to the invention, a heat value of the cushion is reduced; functions of not decaying teeth, removing free radicals, conditioning intestinal tract and the like and an antioxidation function are given to the cushion; and preservation performance of the cushion is improved, so that shelf life is prolonged.
Owner:吉林省益尔生物有限公司

A method for recycling activated carbon after waste mercury catalyst treatment

InactiveCN105060292BEmission reductionImprove active efficacyCarbon compoundsActivated carbonFiltration
The present invention relates to the technical field of activated carbon recycling in disposing of a waste mercury catalyst, in particular to a method for recycling activated carbon after disposing of the waste mercury catalyst. The method comprises: adjusting waste residue containing activated carbon obtained after disposing of the waste mercury catalyst into seriflux by adding water; after precipitation and filtration of the seriflux, dissolving mercury-containing components and other impurities soluble in water in the filtrate; putting the filtrate into an absorption slot, and putting the precipitate into a distillation furnace to carry out high temperature treatment at a temperature of 850-900 DEG C after drying the precipitate; and subliming PVC after destruction of the PVC in the activated carbon, and emptying gaps of activated carbon, so as to improve the activity effect of the activated carbon. Compared with fresh activated carbon in terms of the activity effect, when disposing of an equal amount of colored wastewater, the dosage of the activated carbon is 0.05-0.07 times higher than the dosage of the fresh activated carbon; and discharge of mercury during the process of recycling and disposing the activated carbon is reduced, and the environmental pollution rate is reduced.
Owner:贵州蓝天固废处置有限公司

Operation method for biodegradation of chemical wastewater

The invention provides an operation method for biodegradation of chemical wastewater, belonging to the technical field of chemical wastewater treatment. The invention aims to solve the problem of incomplete chemical wastewater degradation treatment in the prior art. The operation method comprises the following steps: oil separation treatment, air flotation treatment, oxidation treatment, flocculation treatment, biological treatment, introduction of effluent from a biological filter into a disinfection tank, and sterilization and disinfection, thereby finishing chemical wastewater treatment. According to the invention, chemical wastewater is subjected to biodegradation treatment in multiple modes, organic pollutants in the chemical wastewater are removed through the metabolism effect of microorganisms, and the method has the advantages of low cost and easy operation and is advantageous in treatment of large-flow low-concentration harmful chemical wastewater; an anaerobic biological filter and an aerobic biological filter are arranged in the biological filter, and a pH value in the biological filter is adjusted, so microorganisms in the anaerobic biological filter and the aerobic biological filter are in an optimal environment, the degradation of organic pollutants in the chemical wastewater is accelerated, and the chemical wastewater meets the requirement of up-to-standard discharge.
Owner:YANTAI NANSHAN UNIV
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