30results about How to "Catalytic reaction time is short" patented technology

The invention relates to a synthetic method of vitamin A palmitate. The vitamin A palmitate is synthesized through a chemical enzyme technology, and the method mainly comprises the following steps: 1, hydrolyzing vitamin A acetate by using an alkali solution with an organic solvent as a cosolvent to generate vitamin A alcohol; and 2, extracting the vitamin A alcohol by using an organic solvent, washing the obtained extract liquid with water to remove the cosolvent reacting with palmitic acid, and reacting the vitamin A alcohol with the palmitic acid in a non-aqueous system under the catalysis of immobilized lipase to generate the vitamin A palmitate. The synthetic method provided by the invention adopts the vitamin A alcohol to substitute vitamin A acetate as a substrate in the biological catalysis process, and the vitamin A palmitate to be synthesized through esterification, so the substrate concentration is improved, the conversion rate is high, the reaction time is shortened, the molar ratio of the substrate is reduced, the service life of the immobilized lipase is prolonged, the cost is reduced, industrial production requirements are met, and the gap in the enzyme production of the vitamin A palmitate in the current market is filled.

The invention discloses a method for synthesizing betulic acid by carrying out biocatalysis on betulin, comprising the following steps: (1) preparing armillaria luteo-uirens ZJUQH wet cells; (2) adding armillaria luteo-uirens ZJUQH wet cells into ionic liquid or a two-phase system for pre-culture to obtain a pre-culture system; (3) adding betulin solution in the pre-culture system for fermentation culture for 6-24 hours at 25-30 DEG C to obtain transformed culture solution; (4) processing the transformed culture solution to obtain betulic acid. The two-phase system is mixed solvent of ionic liquid and normal hexane, or mixed solvent of ionic liquid and phosphoric acid buffer solution. Compared with a conventional method, the inventive method has higher product yield, shorter catalytic reaction time, simple product separation, lower volatility of ionic liquid system, better biocompatibility and no pollution to the environment.

The invention provides a 3:1 type Mg / Li bimetallic catalyst, a preparation method therefor and an application of the 3:1 type Mg / Li bimetallic catalyst. The preparation method for the catalyst comprises the steps: (1) preparing an N,N,O-trident alkamine ligand; and (2) under the conditions of inert gas protection and ice water bath, dropwise adding a 1.5-times amount of n-butyl lithium into an ether solution of alkamine, dropwise adding a 0.5-time amount of dibutyl magnesium into the obtained reaction solution, then, dripping a 0.5-time amount of aqueous ether solution, carrying out filtrating after the reaction is completed, and carrying out vacuum concentration on the filtrate, so as to separate out colorless transparent crystals. The preparation method for the catalyst is simple and convenient and is low in condition requirements, non-transition metals, i.e. lithium and magnesium which are cheap and are low in toxicity are used as catalytic active metals, an Meerwein-Ponndorf-Verley (MPV) reaction for preparing corresponding first-level and second-level alcoholic compounds through reducing different types of aldehyde and ketone compounds has relatively high selectivity and catalytic activity, and the catalytic reaction is short in time and high in yield, so that the catalyst has a very good industrial application prospect.

The invention discloses a continuous hydrogenation reduction reaction system, which comprises a hydrogen circulation device, a reaction device and a gas-liquid separation device, wherein the hydrogencirculation device, the reaction device and the gas-liquid separation device are sequentially connected through a pipeline, one side of the hydrogen circulation device is connected to the reaction device through a pipeline, and the other side of the hydrogen circulation device is connected to the gas-liquid separation device through a pipeline. According to the present invention, with the continuous hydrogenation reduction reaction system, the hydrogen recovery and use problem is successfully solved by recycling hydrogen so as to effectively save the energy and reduce the environment pollution, and the supported catalyst is added into the reactor so as to eliminate the catalyst separation device and the catalyst separation step, such that the production period is shortened, the productionefficiency is improved, and the application prospect is broad.

The invention belongs to the technical field of preparation of sorbic acid, and particularly relates to a method for preparing sorbic acid through photo-efficient catalytic isomerization, and the method comprises the following steps: (1) putting sorbic acid polyester into a reaction kettle, adding deionized water, turning on a light source, putting a solid base catalyst, stirring and heating to react; (2) after the reaction is finished, filtering while hot to obtain a sorbic acid aqueous solution; (3) cooling, crystallizing, washing and drying to obtain the sorbic acid, wherein the solid basecatalyst is supported anion exchange resin, macroporous anion resin is taken as a carrier, EDTA (Ethylene Diamine Tetraacetic Acid) is taken as a complexing medium, palladium, platinum, zinc or copperions are supported, and the loading capacity is 0.1-1wt%. According to the method, the photocatalysis technology is simple and convenient to operate and environmentally friendly, the adopted supported ion exchange resin is high in alkalinity and short in catalytic reaction time, the production efficiency is improved, meanwhile, the supported metal ions and a light source have a synergistic promotion effect on isomerization, and the amount of byproduct tar can be further reduced.

The invention discloses a method for directly synthesizing aniline from benzene and ammonia by one step, which takes benzene as a raw material, ammonia as an aminating agent, hydrogen peroxide as an oxidizer, acetonitrile as a solvent and TS-1 loaded by metal as a catalyst. The method for synthesizing aniline by one step has the characteristics of high yield of aniline, mild reaction condition, simple catalyst preparing process and easily obtained cheap raw materials, thus being a green synthesis method which has low cost and high yield and is simple and practicable.

The invention provides a kind of nitroreducing Pseudomonas (Pseudomonas nitroreducens) 5-hydroxymethylfurfural oxidase and a preparation method thereof, specifically cloning the DNA sequence of the 5-hydroxymethylfurfural oxidase into a plasmid, And the recombinant plasmid is integrated into the host bacteria to obtain a genetically engineered strain that can express the enzyme heterologously, and the 5-hydroxymethylfurfural oxidase prepared by the heterologous expression of the strain can oxidize 5-hydroxymethylfurfural into 2 ,5‑furandicarboxylic acid, 2,5‑furandicarbaldehyde and 5‑formyl‑2‑furandicarboxylic acid. This patent provides a technical basis for the preparation of furan bulk chemicals by biologically oxidizing 5‑hydroxymethylfurfural.

The invention provides a method for crosslinking modification of microfiber collagen by multistep continuous enzyme catalysis, comprising the following steps: dispersing a microfiber collagen raw material in deionized water to prepare mixed liquor, weighing transglutaminase, adding the transglutaminase into the mixed liquor and carrying out a catalytic reaction for 0.5-3 h, weighing enzyme A and adding the enzyme A into the mixed liquor to continue the catalytic reaction for 0.5-2 h, and finally centrifuging the mixed liquor to obtain a precipitate and postprocessing the obtained precipitate to obtain cross-linked modified microfiber collagen. By the method, the microfiber collagen is cross-linked in a short time through multistep enzyme catalysis. Thereby, modified microfiber collagen with improved mechanical properties, heat stability and enzymolysis resistance is prepared, and the product has a biological activity and is safe and non-toxic.

The invention relates to a nitrogen and oxygen ion containing lithium and magnesium bimetallic catalyst and a preparation method thereof and application thereof and belongs to the technical field of bimetallic catalysts. According to the nitrogen and oxygen ion containing lithium and magnesium bimetallic catalyst, technical problems, in an existing catalyst used in the MPV reaction, that the structure is complicated, the preparation is uneasy, the catalyst activity is not high enough, the usage is large and the reaction time is long are mainly solved. According to the technical scheme, the preparation method of the nitrogen and oxygen ion containing lithium and magnesium bimetallic catalyst comprises the following steps of 1) preparing a N, N, O-tridentate alkamine ligand: preparing the N,N, O-tridentate alkamine ligand according to the prior art; and 2) preparing the nitrogen and oxygen ion containing lithium and magnesium bimetallic catalyst: under the atmosphere of nitrogen, usingn-butyllithium to to remove hydrogen from the N, N, O-tridentate alkamine ligand in ethyl ether solution at 0 degree centigrade; after the solution recovers to the room temperature, stirring the solution for 1-2 hours; and then slowly dripping 0.5 equivalents of dibutyl magnesium into the solution at 0 degree centigrade; continuing to stir the solution for 4-6 hours; after the reaction is finished, filtering a reaction solution; concentrating a filter liquor in a vacuum state to separate out colorless and transparent crystals, wherein the colorless and transparent crystals are the nitrogen andoxygen ion containing lithium and magnesium bimetallic catalysts.

The invention discloses a supramolecular polymer as well as a preparation and application method thereof. The supramolecular polymer is characterized by being formed by complexation of 3,3',5,5'-tetramethyl benzidine and Fe<2+> with a Fe-N coordination bond and taking the 3,3',5,5'-tetramethyl benzidine, the Fe<2+> and an anion associated with the Fe<2+> as a repeating unit. The preparation methodcomprises the following steps: the 3,3',5,5'-tetramethyl benzidine and a ferrous salt solid or solution are subjected to ultrasonic vibration in ethanol with a water content of not more than 10% to form the supramolecular polymer. The supramolecular polymer utilizes the Fe<2+> to catalyze peroxide groups to form oxygen molecules, and the oxygen molecules rapidly oxidize the 3,3',5,5'-tetramethylbenzidine, so that a blue-green color is shown. The invention also discloses a method for detecting the peroxide content in grease by utilizing the supramolecular polymer, peroxide values of various edible oil on the market are measured, the reaction is sensitive, and the color rendering gradient is obvious.

The invention relates to the technical field of clean coal utilization, petroleum refining and oil additives and particularly relates to a method for continuously producing polyoxy dimethyl ether. According to the method, methanol and paraformaldehyde are used as raw materials, a compound multifunctional catalyst is adopted at a catalyst, and polyoxy dimethyl ether is produced continuously on a liquid fixed bed. The method comprises the step that methanol, methylal or a methanol-methylal mixture catalytically reacts with formaldehyde, metaformaldehyde, dimethyl ether or a formaldehyde-metaformaldehyde-dimethyl ether mixture in an acidic liquid fixed bed reactor at 100-150DEG C under 0.01-0.15MPa under the action of the compound multifunctional catalyst. The invention invents and prepares the multifunctional catalyst, invents and creates the high-efficiency liquid fixed bed reactor which is simple in structure, easy to control and high in through-put capacity, innovates an extreme synthesis way of using the catalyst excessively, and adopts ultrasonic and membrane technologies in final refining so as to explore a new way to remove residual waste acid from liquid material except by hydrogenization and an anion-cation bed, thus forming a complete set of technology for continuously and efficiently preparing polyoxy dimethyl ether from methanol or methylal and formaldehyde, trioxymethylene or paraformaldehyde.

The invention relates to a photocatalysis and biological treatment combined drinking water treatment method. The invention relates to a water treatment method. The invention solves the problems that a photocatalysis water treatment method has high cost, difficult degradation, low efficiency of biological organic matter degradation and bad effects of removing ammonia nitrogen; and the microbe content in the water treated by a biological method is incapable of reaching standards. The method comprises the following steps: 1, introducing raw water into a photocatalytic reactor for carrying out a photocatalytic reaction; 2, carrying out the biological treatment of the water processed in step 1; and returning the outputted water after the biological treatment to the photocatalytic reactor for sterilization, and realizing the treatment of the raw water. The water treatment technology combining the photocatalysis and biological treatment has low cost and high water treatment efficiency. The microbe content in the treated water meets the drinking water sanitary standards. The method is suitable for the treatment of drinking water.

The invention relates to a magnetic pentacoordinate mononuclear cobalt complex, a synthesis method and an application thereof, belonging to the technical field of catalyst preparation. The purpose of the invention is to solve the technical problems of complex structure, difficult preparation, insufficient catalyst activity, large dosage and long reaction time of existing catalysts. The technical solution adopted in the present invention is that the synthesis steps are: under the protection of an inert gas, the ether solution of tetramethylethylenediamine is added to cyclohexanone after n-butyllithium lithiation, and after stirring for 1-2 hours Slowly add anhydrous cobalt chloride into the acetone bath, return to room temperature and stir for 2-4 hours. After the reaction is completed, the filtrate is concentrated in vacuo, and a purple transparent crystal is precipitated, which is a magnetic pentacoordinated mononuclear cobalt complex. The compound synthesized by the present invention is prepared by "one-pot method", the preparation process is simple, the raw materials are easy to obtain, and the reaction conditions are mild; as a catalyst, it has high selectivity to the MPV reaction of aldehydes and ketones, and can efficiently synthesize the corresponding of alcohol compounds.

The invention discloses a supramolecular polymer as well as a preparation and application method thereof. The supramolecular polymer is characterized by being formed by complexation of 3,3',5,5'-tetramethyl benzidine and Fe<2+> with a Fe-N coordination bond and taking the 3,3',5,5'-tetramethyl benzidine, the Fe<2+> and an anion associated with the Fe<2+> as a repeating unit. The preparation methodcomprises the following steps: the 3,3',5,5'-tetramethyl benzidine and a ferrous salt solid or solution are subjected to ultrasonic vibration in ethanol with a water content of not more than 10% to form the supramolecular polymer. The supramolecular polymer utilizes the Fe<2+> to catalyze peroxide groups to form oxygen molecules, and the oxygen molecules rapidly oxidize the 3,3',5,5'-tetramethylbenzidine, so that a blue-green color is shown. The invention also discloses a method for detecting the peroxide content in grease by utilizing the supramolecular polymer, peroxide values of various edible oil on the market are measured, the reaction is sensitive, and the color rendering gradient is obvious.

The invention provides a catalyst for catalyzing conversion of silicon tetrachloride and a preparation method thereof, the catalyst has a core-shell structure, the core comprises a catalyst carrier, and the shell comprises an active component; wherein the active component comprises a silicon-copper multi-component alloy, elemental copper and nano ceramic, and the silicon-copper multi-component alloy comprises silicon, copper, transition metal elements and / or rare earth elements. The catalyst disclosed by the invention is applied to a cold hydrogenation reaction process, silicon tetrachloride directly reacts with an active component silicon-copper phase and elemental copper in the catalyst, so that the catalytic reaction time is greatly shortened, and the catalytic reaction rate and the conversion rate can be effectively improved; the catalyst prepared by the preparation method of mechanical alloying has the advantages of abundant pore diameters, fine crystal grains and high defect density.

The invention discloses a continuous hydrogenation reduction reaction system, which comprises a hydrogen circulation device, a reaction device and a gas-liquid separation device. The hydrogen circulation device, the reaction device, and the gas-liquid separation device are sequentially connected through pipelines, wherein one of the hydrogen circulation devices One side is connected to the reaction device through a pipeline, and the other side is connected to the gas-liquid separation device through a pipeline. The continuous hydrogenation reduction reaction system of the present invention not only successfully solves the problem of hydrogen recovery and use by recycling hydrogen, effectively saves energy and reduces environmental pollution, but also saves the need for separating the catalyst by adding a solid-supported catalyst in the reactor. Separation of equipment and steps shortens the production cycle, improves production efficiency, and has broad application prospects.

The invention provides a cage 2-(2-pyridyl)benzimidazole zinc complex, a preparation method and application thereof. The method takes 2-(2-pyridyl)benzimidazole as the ligand, and employs the ligand as a transfer reagent to react with a diethylzinc reagent to synthesize the cage 2-(2-pyridyl)benzimidazole zinc complex, and the cage 2-(2-pyridyl)benzimidazole zinc complex can be used for catalyzing ring opening polymerization of lactide. The preparation method of the complex provided by the invention has the advantages of simplicity, easily available raw materials, mild reaction conditions, and high yield. The complex has high catalytic activity on lactide ring opening polymerization reaction for synthesis of biodegradable polylactic acid materials, and because of the characteristics of good biocompatibility, low toxicity, small environmental pollution, short catalytic reaction time and high yield, the catalyst has very good industrial application prospect.

The invention provides a N,N,O-trident Mg / Li double metal catalyst and a preparation method and an application thereof. The preparation method comprises the following steps: 1) preparing a N,N,O-trident alkamine ligand; and 2) dropwise adding equal equivalent n-butyllithium into an ether solution of alkamine under inertial gas projection and an ice-water bath, dropwise adding equal equivalent dibutyl magnesium into the reaction solution, after reaction, performing filtration, vacuum concentration on the filtrate, and separating out colorless transparent crystals to obtain the catalyst. The catalyst is simple in preparation method and low in condition demand; cheap non-transitional metals lithium and magnesium which are low in toxicity are metals with catalytic activity, and have relatively high selectivity and catalytic activity for an Meerwein-Ponndorf-Verley (MPV) reaction of preparing corresponding first-level and second-level alcohol compounds by reducing different types of aldehyde and ketone compounds. The catalyst is short in catalytic reaction time and high in yield, and has a very good industrial application prospect.

The invention provides a 3:1 type Mg / Li bimetallic catalyst, a preparation method therefor and an application of the 3:1 type Mg / Li bimetallic catalyst. The preparation method for the catalyst comprises the steps: (1) preparing an N,N,O-trident alkamine ligand; and (2) under the conditions of inert gas protection and ice water bath, dropwise adding a 1.5-times amount of n-butyl lithium into an ether solution of alkamine, dropwise adding a 0.5-time amount of dibutyl magnesium into the obtained reaction solution, then, dripping a 0.5-time amount of aqueous ether solution, carrying out filtrating after the reaction is completed, and carrying out vacuum concentration on the filtrate, so as to separate out colorless transparent crystals. The preparation method for the catalyst is simple and convenient and is low in condition requirements, non-transition metals, i.e. lithium and magnesium which are cheap and are low in toxicity are used as catalytic active metals, an Meerwein-Ponndorf-Verley (MPV) reaction for preparing corresponding first-level and second-level alcoholic compounds through reducing different types of aldehyde and ketone compounds has relatively high selectivity and catalytic activity, and the catalytic reaction is short in time and high in yield, so that the catalyst has a very good industrial application prospect.