3results about How to "Increase laser power" patented technology

The application provides a compact laser beam combination quality detection system and method based on a microlens array, which comprises an optical signal detection part and a signal processing system, the optical signal detection part comprises an optical system and a detector, the optical system divides complete laser beams passing through a beam combination system into multiple micro light waves and then converges the multiple micro light waves, the detector detects the light intensity of each micro light wave and records the focus point position, and the signal processing part judges the laser beam combination quality according to the light intensity and the focus point position information obtained by the detector. The compact laser beam combination quality detection system and method based on the microlens array can realize accurate detection of the laser beam combination quality by using only one microlens array and one detector, has a simple structure, a short optical path, and an output signal which does not need complex processing and is convenient to use.

The present invention relates to a method for optimizing mass spectrometer parameters for efficient detection of proteins. By pre-screening the pulsed ion extraction (PIE) value, laser power and / or detector gain value that maximizes the sensitivity and accuracy of the detection signal, the present invention can establish optimal parameters for a target protein using a reference protein having a similar molecular weight to the target protein. Even when a low-resolution mass spectrometry device (e.g., MALDI-TOF) is used, the present invention can detect a trace amount of a target protein with high sensitivity, accuracy and reproducibility, thereby providing a high-sensitivity analysis result that is not affected by changes in the environment at the time of detection. Furthermore, by establishing a linear proportional relationship between the molecular weight of the target protein and the optimal PIE value, and deriving a linear equation therefrom, the present invention can simply calculate the optimal PIE value that maximizes the performance of the mass spectrometer using only the mass information of the target protein, without the need for a reference protein.

This invention discloses an adsorption-type laser drilling platform, comprising a first plate and a second plate. The front of the first plate has several arrayed first grooves, and the top surface of the structural beams around the first grooves is also provided with first adsorption holes. The periphery of the first grooves is also provided with second adsorption holes. The interior of the second plate has a stepped structure, including the first grooves and an extension, with the first plate located on the extension. The top surface of the second plate is provided with third adsorption holes for adsorbing materials. The sidewalls of the second plate are provided with multiple air supply holes. The upper half of the second plate is provided with an air channel, and the air supply holes are connected to the third adsorption holes through the air channel to form an external air path. The lower half of the second plate is also provided with a through-hole cavity air hole, which is connected to the first adsorption holes and the second adsorption holes through the cavity to form an internal air path.