2results about How to "Increase laser power" patented technology

The application provides a compact laser beam combination quality detection system and method based on a microlens array, which comprises an optical signal detection part and a signal processing system, the optical signal detection part comprises an optical system and a detector, the optical system divides complete laser beams passing through a beam combination system into multiple micro light waves and then converges the multiple micro light waves, the detector detects the light intensity of each micro light wave and records the focus point position, and the signal processing part judges the laser beam combination quality according to the light intensity and the focus point position information obtained by the detector. The compact laser beam combination quality detection system and method based on the microlens array can realize accurate detection of the laser beam combination quality by using only one microlens array and one detector, has a simple structure, a short optical path, and an output signal which does not need complex processing and is convenient to use.

The present invention relates to a method for optimizing mass spectrometer parameters for efficient detection of proteins. By pre-screening the pulsed ion extraction (PIE) value, laser power and / or detector gain value that maximizes the sensitivity and accuracy of the detection signal, the present invention can establish optimal parameters for a target protein using a reference protein having a similar molecular weight to the target protein. Even when a low-resolution mass spectrometry device (e.g., MALDI-TOF) is used, the present invention can detect a trace amount of a target protein with high sensitivity, accuracy and reproducibility, thereby providing a high-sensitivity analysis result that is not affected by changes in the environment at the time of detection. Furthermore, by establishing a linear proportional relationship between the molecular weight of the target protein and the optimal PIE value, and deriving a linear equation therefrom, the present invention can simply calculate the optimal PIE value that maximizes the performance of the mass spectrometer using only the mass information of the target protein, without the need for a reference protein.