79results about How to "Particles have good fluidity" patented technology

The invention provides a nickel cobalt manganese hydroxide precursor represented by a general formula (I). The hydroxide precursor is an orderly accumulated sphere with a page-like structure composed of a plurality of layers of sheets. The invention further provides a preparation method of the nickel cobalt manganese hydroxide precursor. In the process of preparing the nickel cobalt manganese hydroxide precursor, a sodium hydroxide solution, an ammonia water solution and a mixed solution of nickel salt, cobalt salt and manganese salt are reacted; and the nickel cobalt manganese hydroxide precursor which is the orderly accumulated sphere with the page-like structure is obtained by controlling pH and the amount of the ammonia water solution in the reaction process and adding an additive for adjusting particle morphology in the reaction process at the same time. The experimental results show that the nickel cobalt manganese hydroxide precursor prepared by the invention has better spherical morphology, uniform particle and good particle mobility; therefore, the nickel cobalt manganese hydroxide precursor is beneficial to diffusing lithium ion in the subsequent sintering process.

The invention discloses a polyolefin catalyst adopting carbon nanotubes as carriers and a preparation method thereof. The polyolefin catalyst adopting carbon nanotubes as carriers comprises carbon nanotube catalyst carriers and catalytic activity components, wherein the polyolefin catalyst contains 80.0 to 99.0% by mass of carbon nanotubes and 1.0 to 20.0% by mass of the catalytic activity components. The preparation method of the polyolefin catalyst adopting carbon nanotubes as carriers comprises the following steps of compounding reaction substances and the carbon nanotube catalyst carriers, and carrying out loading of at least one transition metal compound. The polyolefin catalyst adopting carbon nanotubes as carriers has a spherical particle surface appearance, and contains the catalytic activity components which are uniformly distributed on the surface and in the interior of the spherical polyolefin catalyst adopting carbon nanotubes

The invention discloses a preparation method of beta type ammonium tetramolybdate. Three links of acid precipitation, transformation and drying are improved, wherein the beta type ammonium tetramolybdate transformed in the traditional mode is added in the acid precipitation process, then, the traditional low-temperature transformation or drying transformation mode is changed into the high-temperature transformation, and next, the drying is carried out. During the production transformation, the humidity, the temperature and the pressure required during the transformation are considered, the transformation is carried out at a higher temperature, a certain humidity and a certain pressure, the transformation rate of the beta type ammonium tetramolybdate is ensured, the transformation time is also shortened, the transformation rate of the ammonium tetramolybdate reaches more than 95 percent, meanwhile, the beta type ammonium tetramolybdate which has high purity and strong forgeability and drawability on deep-processing molybdenum products through the physical performance such as product appearance, granularity, apparent density and crystal structure is prepared, the quality and the performance of the beta type ammonium tetramolybdate are greatly improved, and reliable raw materials are provided for the subsequent deep processing.

The invention discloses a compound amlodipine and valsartan solid preparation and a preparation method thereof. The preparation can be a tablet or a capsule and contains 2.5-10g of amlodipine or pharmaceutically acceptable salt thereof (calculated according to the amlodipine) and 40-640g of valsartan or pharmaceutically acceptable salt thereof (calculated according to the valsartan). The preparation method of the compound amlodipine and valsartan solid preparation comprises the steps of mixing the two medicines and the corresponding medicinal auxiliary materials according to the proportion, mixing with the corresponding lubricant or glidant after granulating in a wet method, and pressing into a tablet or filling into a capsule so as to obtain the compound amlodipine and valsartan solid preparation. In the invention, the tablet or the capsule is prepared after the two active substances with unequal doses are granulated in the wet method, and the method is simple and convenient, is easy to control the quality and is suitable for the industrialized production. More than 85% of the amlodipine in the preparation is dissolved out within 30 minutes, and the invention has favorable market popularization prospect.

The invention discloses a method for preparing superfine granule special type saltcake, which includes the following technical steps: pumping hot water at 40-70 DEG C, and forming a saltcake solution containing a plurality of impurities; concentrating for crystallization by vacuum evaporation after refining impurities; cutting the saltcake solution at a high rotating speed; drying after centrifugal separation, processing by a fluidized bed, separating coarse granule saltcake and obtaining a superfine granule special type saltcake product. The anhydrous superfine granule special type saltcake product obtained by the process method of the invention after high rotating speed cutting and fluidized bed processing has the advantages of good granule fluidness and low possibility of agglomeration. The product can be widely used for preparing sodium sulfide, sodium silicate and the like, and is also used in industries of paper making, glass, printing and dyeing, synthetic fiber, hide manufacture, food, medicine and the like.

The invention discloses a preparation method of a berberine hydrochloride tablet, and the preparation method is applied to the field of pharmaceutical preparation. The berberine hydrochloride tablet consists of a tablet core and a coating material, wherein the tablet core consists of berberine hydrochloride and auxiliary materials, each tablet contains 300mg of the berberine hydrochloride, and the auxiliary materials contains one or a plurality of a filling agent, a disintegrating agent, a lubricant, a surfactant and a wetting agent; a coating layer consists of the coating material and water; the coating layer further contains a plasticizer or an antiadherent, wherein the filling agent contains one or a random composition of starch, lactose, pregelatinized starch and microcrystalline cellulose; the disintegrating agent contains one or a random composition of crosslinking sodium carboxymethyl cellulose, polyvinylpolypyrrolidone, sodium carboxymethyl starch, hydroxypropyl starch and low-substitution hydroxyl propyl cellulose; and the lubricant contains one or a random composition of aerosol, talc powder and magnesium stearate. The method is suitable for the large-scale and long-time production of production departments, and has the advantages of stable technology, no dependence on tablet machines, good particle liquidity and formation, controllable tablet weight difference, stable quality, high tablet core hardness, difficulty in wearing and coating suitability.

The invention disclose an aspirin enteric-coated tablet applied in the technical field of medicine preparations and a preparation technology thereof. The enteric-coated tablet comprises a tablet core and an enteric coating layer. The tablet core comprises aspirin, a filling agent, an adhesive and a glidant. The enteric coating layer comprises an enteric material, a plasticizer, an antiadherent and water. The preparation technology includes mixing blank accessories, granulating the mixed blank accessories and drying to obtain accessory particles, mixing the aspirin and the accessory particles to obtain a totally-mixed particles; subjecting the totally-mixed particles to dry granulation to obtain intermediate particles, tabletting the intermediate particles, coating the tablet core obtained after tabletting to prepare the enteric-coated tablet, and drying the enteric-coated tablet in air. According to the tablet and the preparation technology, aqueous dispersion film is adopted for coating, thus solving latent risks of solvent residue and capability of being flammable and combustible which are produced by coating dissolution by organic solvents. The blank accessories are granulated in a wet method, thus overcoming sticky punch and tablet weight difference over-limit which are caused by tabletting in large batches and for a long time.

The invention provides a preparation method for granulose condensable sugar. The preparation method comprises the following steps: mixing and stirring crystallization agent resistant, overheated and supersaturated cane sugar liquid and powdery condensable sugar seed crystals; after vacuum drying, granulating with a high speed granulator; then forced air drying and dry sieving to obtain a granulose condensable sugar product. The condensable sugar prepared by the preparation method is uniform in grain, high in flow ability and high in yield.

The invention discloses immunity-enhancing effervescent tablets. The effervescent tablets comprise the following components in parts by weight: 50-200 parts of vitamin C sodium, 10-30 parts of taurine, 10-30 parts of zinc gluconate and 10-20 parts of fig extract. In order to solve the problems that existing effervescent tablets comprising vitamin C are great in acidity, relatively great in irritation to oval cavity, throat and esophagus and gastric mucosa if being dissolved and not suitable for being taken for a long time, and vitamin C is likely to be oxidized to lose efficacy in the storage process, the effervescent tablets are likely to be affected with damp to absorb moisture and the like, the invention provides the effervescent tablets which have the functions of enhancing the immunity, clearing away heat and toxic materials, tonifying kidneys and spleen, maintaining beauty and keeping young and the like and further can supplement nutrients required by human body, relieve fatigue and delay senescence.

The invention discloses a preparation method of an anode material of lithium-ion power battery lithium vanadium phosphate, comprising the following steps: adding a LiOH.H2O aqueous solution into the white turbid aqueous solution of NH4VO3, and stirring until the solution is clear; then, adding a nodularizer hydrazine hydrate dropwise until the solution becomes yellowish; adding an (NH4)2HPO4 aqueous solution into the above yellowish solution to cause the solution to gradually become brownish black; adding 1,4-butynediol into the above brownish black solution, and stirring; adjusting the pH to10-14; drying the obtained solution in a kettle to obtain precursor powder; and finally, at the temperature of 700-800 DEG C, calcining the precursor powder under the protection of argon to obtain the porous spherical anode material of lithium vanadium phosphate. The lithium-ion battery prepared from the anode material of lithium vanadium phosphate prepared by the method in the invention has the characteristics of high specific capacity, long cycle life, good charging and discharging performances with high multiplying power and the like.

The invention discloses a preparation method of a composite positive pole material of a lithium sulphur battery. The preparation method comprises the following steps of: (1) utilizing activation and nitrogen doping to simultaneously carry out modification on a carbon aerogel to obtain a modified carbon aerogel material; and (2) slowly adding the modified carbon aerogel in an organic sulfur solution, taking a supercritical fluid as an extraction agent to ultrasonically extract in an extraction kettle under room temperature, carrying out pressure reduction and separation, leaching by an ethanol eluting agent, and drying to obtain the modified carbon aerogel-sulfur composite positive pole material. The material prepared by the preparation method provided by the invention has the advantages that the sulfur content is high, the sulfur particles are small, the granularity is uniformly controllable, and the material simultaneously has higher conductibility, specific surface area and porosity. The recovery of the used organic solvent is simple in the preparation process, the extraction agent is circularly used through compression, the extraction efficiency is high, the operation is simple, and the pollution is not generated.

The invention discloses an olaquindox slow release particle and a preparing method and application thereof. The olaquindox slow release particle is prepared by an olaquindox raw material, a dispersing agent and a release retardant. The preparing method includes the steps of weighing the dispersing agent according to formula proportion, and heating and fusing the dispersing agent to be evenly mixed; adding olaquindox to be evenly stirred; adding the release retardant to be evenly stirred; and conducting fluidized-bed spray granulation nodulizing, cooling, screening and collecting through a scientific process. By means of the olaquindox slow release particle, absorption of olaquindox in the intestinal tract of a target animal can be reduced, the bioavailability of the olaquindox is reduced by about 10%-50%; after the animal eats the olaquindox slow release particle, the olaquindox slow release particle can be released in the intestinal tract in the whole process, and the action concentration and the action time of the olaquindox in the intestinal tract are prolonged. According to the preparing method, in the production process, dust and static electricity are not generated, and cross contamination of feed production is effectively avoided; the slow release particle is good in mobility and dispersibility, feed and drugs can be conveniently mixed, and drug application is convenient.

The invention discloses an asiatic acid salt tablet and a preparation method thereof. A formula of the tablet comprises 1-40 percent of asiatic acid amino butantriol salt, 25-60 percent of a filling agent, 1-10 percent of an adhesive, 0.5-40 percent of a disintegrating agent and 0.1-1.5 percent of a lubricant, wherein the percentage refers to the mass percentage of each component in the total amount of the asiatic acid salt tablet. The method comprises the following steps of: in the terms of the formula, uniformly mixing the smashed and sieved asiatic acid amino butantriol salt, filling agent, adhesive and disintegrating agent; mixing with 5-20 percent by mass of an ethanol solution; pelletizing and drying; mixing with the lubricant; and tableting. The asiatic acid salt tablet disclosed by the invention has high bioavailability.

The invention provides a Levetiracetam medicinal composition and a preparation method thereof. The composition mainly comprises Levetiracetam, polyethylene glycol 6,000 serving as a melting agent and other excipients. The preparation method mainly comprises: preparing medicine particles through a hot melting granulation technique; and pressing into tablets or filling into capsules.

The invention discloses a composition for protecting eyesight. The composition is prepared from, by weight, 30-100 parts of sodium ascorbate, 0.1-1 part of vitamin A, 1-10 parts of xanthophyll, 10-20 parts of taurine and 10-30 parts of flower and fruit tea extract. Aiming at the problems that existing lozenges containing vitamin C are high in acidity after being dissolved, causing serious irritation to the oral cavity, the throat, the esophagus and the gastric mucosa, thus not suitable for long-term use, besides, vitamin C is prone to oxidization and invalidation during storage, and lozenges is liable to absorb moisture, the invention provides the composition which can improve immunity, clear heat, improve eyesight, whiten and nourish skin, and remarkably improve blurred vision, eye dryness, eye distension, ophthalmodynia and phengophobia.

The present invention discloses a choline particle and a preparation method and an application thereof. The preparation method comprises the following preparation steps: step one, crushing choline topass a 20-100 mesh sieve; step two: dissolving a first binder in water to obtain a binder solution; and step three: after mixing the choline processed in the step one with a second binder, putting themixture into a granulator, and adding the binder solution obtained in the step two for granulation to obtain the choline particle. The binder is dissolved in water, then the choline is granulated, the prepared granule is uniform and moderate in size, good in fluidity, and not easy to absorb moisture; and a prepared pressed tablet is smooth on surface, small in difference in tablet weight, good inhardness (good in friability), and good in disintegration.

The invention provides a tildipirosin 1,4-dioxane solvate and a preparation method thereof. Characteristic peaks occur in an X-ray powder diffraction pattern represented by 2theta when 2theta is equal to 6.06+/-0.2, 8.42+/-0.2, 9.34+/-0.2, 9.94+/-0.2, 10.28+/-0.2, 12.34+/-0.2, 13.44+/-0.2, 13.74+/-0.2, 14.66+/-0.2, 15.58+/-0.2, 15.78+/-0.2, 16.40+/-0.2, 17.00+/-0.2, 17.90+/-0.2, 18.60+/-0.2, 19.32+/-0.2, 20.10+/-0.2, 21.40+/-0.2, 22.34+/-0.2, 22.68+/-0.2, 23.34+/-0.2 and 24.18+/-0.2. The preparation method employs a constant-temperature suspended crystal transformation process and is simple in process and low in energy consumption. The tildipirosin 1,4-dioxane solvate is in a rod shape and crystal is of a regular shape.