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47results about How to "Strong selectivity" patented technology

Method for synthesizing PODE through condensation, oxidation, polycondensation and etherification of methyl alcohol

The invention discloses a method for synthesizing PODE through condensation, oxidation, polycondensation and etherification of methyl alcohol. The method includes the steps that firstly, methylal with the mass purity of 85%-99.9% is prepared through a reaction of the methyl alcohol and diluted methanal; secondly, the methylal and air are catalyzed and oxidized by iron-molybdenum catalysts to prepare methanal with the mass purity of not less than 70%; thirdly, the methanal is subjected to polycondensation and then is refined to obtain triformol with the mass purity of not less than 99.9%; fourthly, the methylal and the triformol are subjected to etherification, reactive distillation and dehydration and are refined to obtain PODE3-8 with the mass purity of over 99%. By the adoption of the method, the single-pass yield of the PODE is increased from 40%-50% to 95%, the yield of the PODE3-8 is increased from 20% to 90%, product distribution is more reasonable, and the product purity is improved from 50% to 99%. The PODE is wide in application prospect and remarkable in economic, social and environmental benefit.
Owner:XIAN SHANGHUA TECH DEV CO LTD

Polypeptide targeting human breast cancer cells and application of polypeptide

The invention relates to a polypeptide targeting human breast cancer cells and application of the polypeptide. The polypeptide is as shown in the following general formula: X1LX2X3X4X5X6X7. The invention further relates to a nucleotide sequence encoding the polypeptide and an expression vector expressing the polypeptide, as well as host cells. The invention further relates to the polypeptide, a bivalent, multivalent or polypeptide conjugate formed by the polypeptide and a pharmaceutical composition formed by the targeting polypeptide and a preparation and a developing preparation capable of killing the cancer cells, as well as the application. The polypeptide provided by the invention can realize specific binding with a marker, namely a HER2 protein of the breast cancer cells, and has an obvious targeting effect and strong selectivity; furthermore, the peptide provided by the invention can be prepared by a chemical synthesis method, and has the advantages of high purity, small molecular weight, strong specificity, no immunogenicity, safety and reliability. The polypeptide can be used for preparing a targeting probe and a pharmaceutical carrier against cancers.
Owner:THE NAT CENT FOR NANOSCI & TECH NCNST OF CHINA

Application of PLEKHA5 in preparation of tumor diagnosis reagent

The invention relates to application of PLEKHA5 in preparation of a tumor diagnosis reagent, in particular to a new application of the PLEKHA5 in preparation of an osteosarcoma diagnosis reagent. The inventor analyzes and screens genes by virtue of a bioinformatics method on the basis of a high-throughput sequencing result, and picks out a candidate gene PLEKHA5; furthermore, a molecular cell biology experiment proves that the PLEKHA5 and osteosarcoma have good correlation; and the PLEKHA5 can be used for preparing an auxiliary diagnosis reagent for osteosarcoma, and has important clinical application value.
Owner:北京鸿志合创科技有限公司

Marigold lutein supercritical CO2 extraction method

The invention relates to a method for using above-critical carbon dioxide to extract Tagetes lutein in the field of chemical, foods and health food process applied technology. It also relates to a new type of green entrainer: vegetable oil which can improve the lutien extracting ratio without the organic solvent residual.
Owner:GUANGZHOU LEADER BIO TECH

C22orf26 gene and application of expression product of C22orf26 gene to preparing Parkinson diagnosis and treatment preparation

The invention relates to the field of biological medicine, in particular to a C22orf26 gene and an application of an expression product of the C22orf26 gene to preparing a Parkinson diagnosis and treatment preparation. An inventor carries out analysis with a bioinformatics method based on high-throughput sequencing results to carry out gene screening, and the candidate gene C22orf26 is selected. Further, it is proved that the C22orf26 gene and Parkinson have well correlation through a molecular biology experiment, and the C22orf26 gene can be used for preparing the auxiliary Parkinson diagnosis and treatment preparation, and has important clinical application value.
Owner:QINGDAO MEDINTELL BIOMEDICAL CO LTD

Copper ore processing technology

The invention provides a copper ore processing technology suitable for copper ores of refractory and hard-leaching ores. The copper ore processing technology comprises the steps of leaching, extraction and electro-deposition. Smashed ores are added into a leaching tank, leaching liquid is pump into the leaching tank, the leaching liquid is discharged into a low-position storage tank after a leaching cycle and then is pumped into a high-position storage tank after being filtered by a filtration device, leaching liquid in the high-position storage tank automatically flows into an extract reverse-extraction box, an extract return to a leaching system for recycling, reverse-extraction liquid flows into an electro-deposition tank, and electro-deposition tail liquid flows into an electro-deposition tail liquid storage tank. The copper ore processing technology adopts a compound leaching agent, has good adaptability and vitality and is suitable for leaching of various copper ore resources. A Lix54-199 alkaline copper extraction agent is further used for extraction, so that facilities and equipment do not need anti-corrosion treatment, investment is reduced, the leaching agent can be recycled, cost is saved, and environmental pollution is avoided.
Owner:TIANJIN DEV ZONE JUNCHENG PAPER IND

Method for preparing diethylstilbestrol molecularly imprinted electrochemical sensor based on electropolymerization of p-aminothiophenol film and application thereof

The invention discloses a method for preparing a diethylstilbestrol molecularly imprinted electrochemical sensor based on electropolymerization of a p-aminothiophenol film. The method comprises sequential steps such as glassy carbon electrode pretreatment, electrode modification by multi-wall carbon nanotubes, electrode modification by nano gold, functional monomer self-assembly, template molecular pre-assembly, electropolymerization of the p-aminothiophenol film, and template molecule elution, and an organic phase as a polyelectrolyte solvent improves the number and selectivity of binding sites in a polymer film, and is beneficial to formation of a stable host-guest compound from a template molecule and a function monomer, so that the template molecule can maintain a good rigid structurein a polymer network structure and form a cavity with a memory effect. The preparation method is simple and easy to control, and the sensor has strong selectivity and stability, high sensitivity and low cost. The sensor is suitable for analysis and detection of diethylstilbestrol residues in animal-derived foods, feeds and other samples.
Owner:HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY

Cobalt removing agent and application thereof

The invention discloses a cobalt removing agent and application thereof. The cobalt removing agent consists of dimethyl dithiocarbamate and sodium nitrite; and the ratio of dimethyl dithiocarbamate tosodium nitrite by mass is 12-18: 1. The cobalt removing agent is applied to zinc smelting slag leaching liquid for cobalt removal; the cobalt removing rate is above 99.7%, that is, cobalt can be nearly removed, so that the concentration of cobalt in solution totally meets the zinc electrolysis requirements, meanwhile, higher selectivity is achieved, and manganese ions achieving an electrolysis protecting effect in the solution cannot be removed; and in addition, the cobalt removing process, the grade of cobalt slag obtained after heat treatment of cobalt precipitates is above 58%, and higherrecovery value is achieved.
Owner:CHANGSHA HASKY ENVIRONMENTAL PROTECTION TECH DEV CO LTD

Process for extracting squalene by complex

The invention discloses a process for extracting squalene by complex. The process comprises the following steps of crushing seeds of tea-oil tree, adding petroleum ether, carrying out ultrasonic extraction, filtering, concentrating the filtrate under reduced pressure to obtain a camellia oil fat-soluble substance concentrate; mixing camellia oil fat-soluble substance concentrate with an alcoholic solution of a strong base, heating in a water bath, stirring, refluxing and extracting squalene with petroleum ether to obtain squalene crude product; adding a methanol aqueous solution of silver nitrate into the squalene crude product, under the conditions of oscillation or stirring, carrying out complexation reaction at a low temperature, standing at a low temperature and carrying out liquid separation to obtain an aqueous solution of silver ions-squalene complex as an intermediate product; adding petroleum ether into the aqueous solution of silver ions-squalene complex, heating under reflux, carrying out reverse extraction and then standing and carrying out liquid separation to obtain a dissociated squalene petroleum ether organic phase; cleaning the dissociated squalene petroleum ether organic phase with an aqueous NaCl solution, and then distilling under reduced pressure to recover the organic solvent; cleaning with distilled water again and carrying out vacuum drying to obtain the final product refined squalene.
Owner:NANJING UNIV OF TECH

Macroporous adsorption resin preparation method

The invention relates to a macroporous adsorption resin preparation method, which comprises: preparing a monomer: pouring divinylbenzene, methyl acrylate and dibenzoyl peroxide into a reaction kettle according to a formula, carrying out room temperature stirring for 25-30 min, pouring a pore forming agent cyclohexane, and carrying out room temperature stirring for 25-30 min; preparing a water phase: adding a proper amount of water to the reaction kettle, pouring a powder salt, and stirring to make the salt water achieve a uniform state; pouring gelatin and methylene blue, stirring while heating to a temperature of 55-60 DEG C, and turning off the stirring in advance; sucking the prepared monomer into the reaction kettle, and carrying out heating-free empty stirring for 10-15 min, wherein the temperature of the water phase at the beginning is 55-60 DEG C, and the temperature in the reaction kettle is about 40-45 DEG C after the monomer is poured; slowly heating to a temperature of 68-70 DEG C after the empty stirring is performed for 10-15 min; and carrying out thermal insulation for 4-5 h, carrying out steam heating to slowly increase the temperature to 70-75 DEG C, and carrying out thermal insulation for 6-7 h, wherein the stirring is not turned off during the operation.
Owner:JIANGSU STEVEN BIOTECHNOLOGY CO LTD

Pollution-free biological pesticide insecticide

InactiveCN102715200AStrong selectivityAvoid environmental pollution problemsBiocideAnimal repellantsDiseases insectDisease
The invention discloses a pollution-free biological pesticide insecticide, belonging to the technical field of pesticide. The pollution-free biological pesticide insecticide is prepared from the following raw materials in parts by weight: 10-15 parts of aconitine, 8-12 parts of stellera chamaejasme, 12-16 parts of agrimony pilosa, 8-12 parts of ephedra, 5-8 parts of azedarach and 3-5 parts of high-permeability synergic auxiliary agent. The pollution-free biological pesticide insecticide has the beneficial effects that the selectivity is strong, namely the pollution-free biological pesticide insecticide only acts on target disease insects and minority of organisms tightly correlated with the target disease insects, has no harm to human beings, birds, other insects and mammals, and is low in residue and high in efficacy; a small amount of biological pesticide can exert high-performance action, can be rapidly decomposed, avoids environmental pollution problem brought by the traditional pesticide, and is not easy to generate pesticide resistance.
Owner:陈士忠

Method for determining organic chrominum cross-linkage gel system based on low molecular weight high concentration polymer

The invention provides a method for determining an organic chrominum cross-linkage gel system based on low molecular weight high concentration polymers, comprising steps of: selecting chromium acetate as a primary cross-linking agent; selecting high concentration polymers having a low molecular weight of 4 million as raw materials of profile control agents; For the high concentration polymers having a low molecular weight of 4 million, the concentration is 0.6 to 0.8 percent; the concentration ratio between the high concentration polymers and the first cross-linking agent is 25:1 to 35:1; the intensity of formed gel is 190 to 200mPa.s. The invention has a strong selectivity and is simple in a construction process, moreover the invention can neither bring permanent damage to stratums nor obstruct the performing of later measures.
Owner:武侯区巅峰机电科技研发中心

Special weeding method for paddy rice and upland rice by direct seeding

InactiveCN103766355AEliminate field weed hazardsStrong selectivityBiocideAnimal repellantsWeedRice plant
The invention discloses a special weeding method for paddy rice and upland rice by direct seeding. The special weeding method comprises the following steps: (1) sealing soil: adding 250ml of 60% butachlor, 400ml of 48% butralin, 50g of 50% quinclorac, 50g of 2-methyl-4-chloro-phenoxyacetic acid sodium and 100ml of 33% stomp prowl into each 667M<2>; mixing and adding 75kg of water and agitating uniformly; after seeding for 7-10 days, spraying field soil; (2) treating stems and leaves: mixing 250ml of the 60% butachlor, 25g of the 50% quinclorac and 50ml of Basagran into each 667M<2>; mixing and adding 40kg of the water; agitating uniformly; and spraying weeds in sunny days when barnyard grass has two leaves. With the adoption of a formula of a novel special herbicide for the paddy rice and the upland rice, which is directly sown by the method, the preventing and removing effects of weeds concomitant with the upland rice are up to more than 95% and the field weed dangers are basically eliminated; the selectivity is strong and the inhibition and phytotoxicity are not caused on the growth of rice plants after the medicine is applied; and sprouted seedlings are ordered and the fertility is normal.
Owner:RICE RES INST DANDONG ACADEMY OF AGRI SCI

Pentacyclic triterpenoid compounds, preparation method thereof, and application of compounds to prepare medicines controlling tumors

The invention discloses a kind of pentacyclic triterpenoid compounds, a preparation method thereof, and application of the compounds to prepare medicines controlling tumors. The structural formula of the compounds is shown in the specification, and in the structural formula, R1 is S-phenyl-L-cysteinyl, R2 is hydrogen or carbonyl, and R3 and R4 are selected from COOH, -CH3 and -COOCH3. The pentacyclic triterpenoid compounds have the advantages of being efficient, low in toxicity, high in selectivity and high in specificity.
Owner:LIAONING NORMAL UNIVERSITY

Vehicle intelligent control device

The invention provides a vehicle intelligent control device comprising a vehicle-mounted terminal device and a mobile terminal device that communicate with each other. The vehicle-mounted terminal device comprises a first near field communication unit, a vehicle state data collection unit and a vehicle control data transmission unit. The mobile terminal device comprises a second near field communication unit, a vehicle state display unit and a vehicle control unit. According to the vehicle intelligent control device, a terminal having an NFC function is mounted on a vehicle end based on near field communication technologies, and a vehicle-mounted diagnosis system interface which is available in every conventional vehicle is used for transmitting all important parameter data of an inner part of a vehicle; a mobile terminal is used for fulfilling a real time vehicle performance monitoring function, an intelligent vehicle control function, an emergency cloud data backup function, a convenient payment function and the like.
Owner:PHICOMM (SHANGHAI) CO LTD

Steel plate for acetabulum

The invention belongs to the technical field of medical instruments, and particularly relates to an anatomic steel plate for acetabulum, which consists of a plate body and two end wings. The plate body is in the shape of a 'top hat', the middle arch has a radian and is matched with the anatomic shape of the acetabulum, and the two end wings are tilted slightly so as to be matched with the anatomic shape of the nodule extension positions between the acetabulum and the upper ilium bone and between the acetabulum and the lower ischium. The plate body of the steel plate is uneven in width, and at the joints of the sides of the plate body with the edge of a back wall of the acetabulum, one side of the plate body contacts with the posterior column of the acetabulum, the middle of the plate body is in transition gradually, and the other side of the plate body contacts with the ilium. The integral design of the width of the plate body is consistent with variation of the thickness of the bone mass of the acetabulum, and the middle of the steel plate for the acetabulum is slightly wider than the two end wings, and is provided with multi-angle lock screw holes, dual-purpose screw holes and Kirschner wire holes. The anatomic steel plate for the acetabulum can be used after being adjusted slightly according to fracture condition during surgery, is fit with local bone mass well, free of forming larger slots and capable of preventing screws entering an articular cavity when in implanting of the screws.
Owner:谢友军

Method for extracting total tannin in rhodomyrtus tomentosa rhizome by using supercritical carbon dioxide

The invention relates to a method for extracting total tannin in rhodomyrtus tomentosa rhizome by using a supercritical carbon dioxide technique. The method comprises the following steps: pressurizing food-grade CO2 to convert food-grade CO2 into supercutical fluid as an extraction solvent, adding an entrainer for improving the extraction efficiency, crushing the rhizome of rhodomyrtus tomentosa, soaking the crushed rhizome of rhodomyrtus tomentosa, putting the soaked rhizome of rhodomyrtus tomentosa into an extraction kettle, selecting appropriate process parameters such as temperature, pressure, time, an entrainer and concentration so as to obtain an extract, diluting the extract, then inspecting the diluted extract according to a tannin testing method issued by China Veterinary Pharmacopoeia, and calculating the tannin content of the extract. The method is simple, economical and high in operability of process procedures and can be applied to industrial production, and the obtained rhodomyrtus tomentosa tannin can be applied to Chinese medicine production.
Owner:GUANGXI VETERINARY RES INST

Copper sulfide ore flotation collecting agent

InactiveCN108499744AStrong collection performanceStrong selectivityFlotationCopper sulfideXanthate
The invention relates to the technical field of copper sulfide ore flotation, in particular to a copper sulfide ore flotation collecting agent. The copper sulfide ore flotation collecting agent comprises, by mass, 60%-90% of xanthate diester, 10%-40% of butyl ammonium black medicine, and 0%-5% of adjusting agent. The xanthate diester is provided with a certain grade. After the technical scheme isadopted, the copper sulfide ore flotation collecting agent has the beneficial effects of being high in collecting performance and selectivity; single collecting agent PJ is adopted by rough selection,fine selection and scavenging, the copper concentrate with high copper recovery rate and higher copper grade can be obtained simultaneously; the flotation process is not affected by the recycling ofthe production water return, the production index is stable, and the process control is simple; and the price is low, the usage amount of the collecting agent, lime and foaming agent can be greatly reduced, and the production cost is greatly reduced.
Owner:福建紫金选矿药剂有限公司

Compound amine absorbent for absorbing sulfur dioxide and preparation method thereof

The invention provides a composite amine absorbent for absorbing sulfur dioxide and a preparation method thereof, belonging to the field of gas purification and recovery, and the composite amine absorbent comprises the following components in percentage by mass: 30-50% of piperazine and derivatives thereof, 0.5-10% of an activator, 1-5% of a pH corrosion inhibiting solution, 0.1-0.5% of a defoaming agent and the balance of water. The preparation method comprises the following steps of: adding the piperazine and derivatives thereof, the activator, the pH corrosion inhibitor and the defoaming agent into the water according to a certain proportion, dissolving and stirring uniformly. The composite amine for absorbing the sulfur dioxide gas adopts the piperazine as an absorbent main body, and has the characteristics of low viscosity and strong sulfur dioxide absorption selectivity; the saturated absorption capacity can reach 2.6 mol / mol of amine, and the composite amine absorbent has a highdesorption capacity of 1.53 mol / mol. Compared with that of absorption solutions commonly used in industry, the desorption capacity of the composite amine absorbent after multiple absorption can stillreach more than 98%. In addition, the composite amine absorbent is added with a pH slow release liquid to reduce the corrosivity of the amine absorbent to equipment.
Owner:西安悟能环境工程有限公司

Preparation method of novel isocyanate-based silane

The invention relates to a preparation method of novel isocyanate-based silane. The method comprises steps as follows: (1) aminoalkoxy silane and dialkyl carbonate react at the temperature of 30-80 DEG C to produce carbamate-based alkoxy silane; (2) carbamate-based alkoxy silane is split under the catalysis of a catalyst to produce isocyanate-based silane. Prepared isocyanate-based silane can greatly reduce the resin viscosity, thus, more filler can be added, the glue mixing cost is reduced, meanwhile, the mechanical property is improved, the resin activity is improved, and the dosage of tin catalysts is reduced. The selectivity of the used catalysts is high, the raw material conversion rate is high, and the product yield is high.
Owner:山东禹王和天下新材料有限公司

High-Q cross-coupled slot waveguide microwave filter

The invention relates to a high-Q cross-coupled slot waveguide microwave filter, comprising a rectangular metal bottom plate, a plurality of metal stand columns, a metal square column and a metal topplate; the metal stand columns are positioned on the metal bottom plate, the metal square column is used for supporting the structure, an air gap is reserved between the metal stand column and the metal top plate and constitutes an electromagnetic band gap structure together with the metal stand columns, the metal bottom plate and the metal top plate, the metal stand columns together with the metal bottom plate and the metal top plate forms five cuboid cavities, five resonant cavities are formed, two rows of metal stand columns are arranged between the adjacent resonant cavities and are used for energy coupling between the adjacent resonant cavities, metal round columns are respectively arranged at the centers of the first cavity, the second cavity, the third cavity and the fifth cavity onthe metal bottom plate, two metal circular holes are formed in the metal top plate right above the first cavity and the fifth cavity, the two metal circular holes are arranged as two feeding ports, and the two feeding ports are used for feeding the filter from the top side through a coaxial probe. The filter has a relatively high load-free quality factor; and meanwhile, the filter has the characteristic of being higher in selectivity.
Owner:广东昌宝科技股份有限公司

Coking slop oil tank waste gas deodorization purifying device based on chemical absorption method

The invention discloses a coking slop oil tank waste gas deodorization purifying device based on a chemical absorption method. The coking slop oil tank waste gas deodorization purifying device comprises a sewage tank, a coking slop oil tank, a buffer tank, a first ejector, an absorption agent circulating pipe, an air guide pipe, a first circulating tank, a pump I, a spraying head, a first absorption tower, a second absorption tower, a second ejector, a second circulating tank, a pump II and an exhaust cylinder, wherein waste gas of the coking slop oil tank and the sewage tank are concentrated to be guided out, and a great amount of oil gas and vapor, which are likely to condensate, are separated by virtue of the buffer tank, and then enter the absorption tower. Secondary cyclone plate towers are connected in series for the circular absorption, the secondary parallel-connection ejectors are installed in front of and behind the absorption towers to be used as power for guiding the gas, then an absorption agent and the waste gas are adequately mixed and absorbed again in the ejectors, and after the gas-liquid separation in the absorption agent circulating tank, the mixed liquid enters the exhaust cylinder to be discharged. The coking slop oil tank waste gas deodorization purifying device is a special petrochemical waste gas purifying device based on the chemical absorption method and has advantages of high reaction speed, high selectivity, good absorption effect, simple process, convenience in operation, safety, reliability and the like.
Owner:上海景凯环保科技有限公司

Biological pesticide insecticide without pesticide resistance

InactiveCN104488999AStrong selectivityAvoid environmental pollution problemsBiocideAnimal repellantsBacillus cereusBiopesticide
The invention discloses a biological pesticide insecticide without pesticide resistance. The biological pesticide insecticide comprises the following substances in parts by weight: 15-32 parts of silicate bacterium powder, 9-26 parts of dodecyl dimethyl betaine, 1-5 parts of rhizoma gastrodiae, 15-33 parts of camphora oil, 20-26 parts of diatomite, 1-9 parts of green muscardine fungus powder, 19-38 parts of bacillus cereus powder, 11-22 parts of dodecylbenzene sulfonic acid, 5-11 parts of methyl benzoate, 25-30 parts of cymbopogon citratus oil, 10-19 parts of nisinasu and 6-17 parts of chaetocladium arbuscularmycorrhize powder. The biological pesticide insecticide disclosed by the invention has the advantages that the selectivity is strong, the low-residue and high-efficiency effects are achieved, the high-efficiency action can be exerted by a small amount of biological pesticide, and the biological pesticide insecticide can be rapidly decomposed, so that the problem of environmental pollution caused by a traditional pesticide is avoided on the whole; and the pesticide resistance is not prone to generate.
Owner:QINGDAO LAOXIANG TEA PROD

Triazolopyrimidine sulfonamide compound as well as preparation method and application thereof

The invention provides a triazolopyrimidine sulfonamide compound, which has a structural formula as shown in the formula (I) as below, wherein R is a chlorine atom or a methoxycarbonyl group. According to triazolopyrimidine sulfonamide compound provided by the invention, an ortho-position and a para-position on a benzene ring are substituted, a para-substituent is nitryl, and an ortho-substituentis the chlorine atom or the methoxycarbonyl group. The compound is simple in structure, and has higher weeding activity and higher safety on crops at the same time. The invention also provide a preparation method and application of the triazolopyrimidine sulfonamide compound.
Owner:SHENZHEN UNIV

Biological fermentation soil restoration method for removing heavy metal lead

The invention discloses a biological fermentation soil restoration method for removing heavy metal lead. According to the method, the biological fermentation characteristics of oxidation staphylococcus bacillus are creatively utilized; under the participation of D-sorbitol and various inherent nutrient contents in the soil, a lactonization reaction takes inside the oxidation staphylococcus bacillus; finally, L-ascorbic acid (vitamin C) is produced through fermentation; then, the L-ascorbic acid can be combined with the heavy metal lead to produce non-toxic inorganic salts with the density being obviously greater than that of soil particles; and the inorganic salts can be separated and removed from the soil through vibration sorting operation. Meanwhile, the cost of the L-ascorbic acid produced by the D-sorbitol participating in the biological fermentation reaction is much lower than the cost of directly adding the L-ascorbic acid into the soil; and the material cost of the soil restoration treatment can be greatly reduced.
Owner:中水卫士生态科技有限公司

Intracranial aneurysm marker ODAM and application thereof

The invention relates to an intracranial aneurysm marker ODAM and application thereof, in particular to a marker ODAM gene and application of expression products in preparing diagnosis and treatment preparations for intracranial aneurysm. High-throughput sequencing is carried out on intracranial aneurysm cases by the inventor, candidate genes ODAM with low expression are selected from genes with obvious difference expression, and low expression of ODAM in intracranial aneurysm tissue is verified through further molecular verification. By means of the intracranial aneurysm marker ODAM and the application thereof, a new monitoring and treating target of intracranial aneurysm is provided, and significant clinical application value is achieved.
Owner:SICHUAN PROVINCIAL PEOPLES HOSPITAL

Method for extracting onion seed oil by supercritical carbon dioxide

InactiveCN101451090AStrong selectivityActive ingredients less damageFatty-oils/fats productionChemistryActive ingredient
The invention relates to a method for extracting onion rapeseed oil from onion rapeseeds through supercritical carbon dioxide, which belongs to the filed of processing of agricultural and sideline products and is specially used for developing and utilizing the onion rapeseed oil. The raw materials and the technology comprise the following: onion rapeseeds are dried and crushed and subjected to supercritical CO2 extraction; the extraction temperature is adjusted to be between 35 and 45 DEG C, the extraction pressure is adjusted to be between 15 and 25 MPa, and the extraction time is adjusted to be between 30 and 90 minutes; the onion rapeseed oil is obtained; and the purity of the onion rapeseed oil is more than 99.2 percent, and the yield of the onion rapeseed oil is 12.08 percent. The invention provides an advanced method for extracting the onion rapeseed oil. The method has the advantages of strong maneuverability, good safety, small damage to active ingredients, high yield and good repeatability.
Owner:NANJING AGRICULTURAL UNIVERSITY

Lysine derivative histone deacetylase inhibitor, synthesis and application

The invention discloses a lysine derivative histone deacetylase inhibitor. The inhibitor has high selectivity, can be used for Sirtuin mechanism inhibitor antitumor drugs with strong Sirtuin selectivity, high efficiency and low toxicity, has easily available raw materials, and is low in cost.
Owner:GUIZHOU MEDICAL UNIV

Ion chromatography-online pretreatment analysis system for determining heavy metal chromium (VI) in donkey-hide gelatin

ActiveCN103091414AStrong selectivityReduced sample preparation processComponent separationChromatographic columnIon exchange
The invention relates to a use system of chemical apparatus analysis, and particularly to an ion chromatography-online pretreatment analysis system for determining heavy metal chromium (VI) in donkey-hide gelatin. A simply processed donkey-hide gelatin sample passes through a polymer reversed-phase column, interfering substances in the donkey-hide gelatin are removed online under an alkali condition, then the processed sample solution is enriched in an enriching pipe by an ion chromatography-valve switching technology and is separated through an anion exchange chromatographic column, and then post-column derivatization visible light detection is carried out. As the ion chromatography-online pretreatment analysis system adopts an ion chromatography-online pretreatment analysis technology, fussy sample pre-treatment processes can be reduced and even omitted, the sample analysis time is shortened, and the detection efficiency is enhanced. By virtue of the post-column derivatization visible light detection, no other interfering ions appear and the selectivity is good. The ion chromatography-online pretreatment analysis system can be suitable for a series of other problems of separation and detection on ions in complex matrixes, and has a high practical value.
Owner:ZHEJIANG UNIV +1

Method for synthesizing benzofuran derivatives in one pot process

The invention relates to a method for synthesizing benzofuran derivatives in a one pot process, which includes the following steps: (1) adding quaternary phosphonium salt or phosphite ester salt and inorganic alkali or organic alkali in salicylaldehyde or salicylaldehyde derivatives, mixing and stirring materials in solvents or leading the materials to be in solid phase and to be grinded for reaction in solvent-free conditions so as to generate 2-styryl phenol derivatives, and (2) adding oxidants into the 2-styryl phenol derivatives obtained through the step (1) in normal position mode for oxidation and cyclization to obtain the benzofuran derivatives. The method has the advantages of being simple and smooth by operating in the one pot process, mild in conditions, easy to magnify, especially suitable for industrial production, wide in application range, high in yield and low in cost.
Owner:BEIJING NORMAL UNIVERSITY
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