35 results about "Acetate compound" patented technology

The invention provides a composite catalyst and a preparation method thereof, and a synthesis method of a p-methoxy cinnamate compound. The composite catalyst comprises a carrier modified by a modifier, and a metal salt and a choline substance loaded on the carrier. In the presence of the composite catalyst provided by the invention, a Claison-Schmidt condensation reaction of an aromatic aldehyde compound and an acetate compound is catalyzed to obtain the p-methoxycinnamate. The composite catalyst provided by the invention has the advantages of high reaction activity and selectivity, stable catalyst structure, difficult loss of active components, realization of cyclic application of the catalyst, no need of frequent replacement of the catalyst, simple operation, facilitation of continuous industrial production, substantial increase of the equipment utilization rate, and realization of industrial production. By using the composite catalyst provided by the invention, the p-methoxy cinnamate compound can be prepared under relatively mild reaction conditions, and the composite catalyst has no corrosion to equipment, does not generate waste water and waste salt, and is green and environment-friendly.

The invention provides a catalyst component for olefin polymerization, a preparation method of the catalyst component, a catalyst and application of the catalyst component. The catalyst component is prepared by reacting raw materials including a magnesium compound, a precipitation aid, a titanium-containing compound, an acetate compound, an organic alcohol compound, an organic aluminum compound N and an electron donor compound. The catalyst provided by the invention is used for preparing special / ultra-high molecular weight polyolefin through olefin polymerization reaction, and the prepared polymer has the advantages of controllable molecular weight, narrow molecular weight distribution, low hexane extract content, low large particle and fine powder content, low branching degree, high sphericity and better low entanglement performance.

The invention discloses a low-cost synthesis method of a furan acetate compound, which is characterized in that a derivative of bio-based furfuryl alcohol, namely a furfuryl ester compound, is used as a raw material, carbon monoxide gas is selected as a carbonyl source, and carbonylation reaction is carried out under the combined action of an organic solvent and a catalyst. The catalyst is composed of an eighth group metal salt and a phosphine ligand, and finally the furan acetate compound is generated. Compared with a publicly reported route for synthesizing the furan acetate compound through carbonylation by taking furfuryl alcohol as a raw material, the preparation route disclosed by the invention has remarkable advantages, additives such as alkali and dimethyl carbonate do not need to be used, and the production cost is effectively reduced on the premise of ensuring high yield of furan acetate.

The present invention relates to halogenated alkenylalkoxymethyl ether compounds of the following general formula (1): R 1 CH2OCH2OCH2CH2CH=CH(CH2) a X 1 (1), wherein R 1 represents a hydrogen atom, a n-alkyl group having 1 to 9 carbon atoms, or a phenyl group, X 1 represents a halogen atom, and a represents an integer of 3 to 14. The present invention also relates to a method for producing terminal conjugated alkadien-1-yl acetate compounds of the following general formula (5): CH2=CHCH=CH(CH2) a OAc (5), wherein a is defined as above, and Ac represents an acetyl group, and a method for producing terminal conjugated alkadien-1-ol compounds of the following general formula (6): CH2=CHCH=CH(CH2) a OH (6), wherein a is defined as above.

The present invention provides a composite catalyst and a preparation method thereof and a synthesis method of p-methoxycinnamate compounds, wherein the composite catalyst includes a carrier modified by a modifier and a metal salt and a choline substance supported by the carrier. In the presence of the composite catalyst of the present invention, a Claison-Schmidt condensation reaction is catalyzed between aromatic aldehyde compounds and acetate compounds to obtain p-methoxycinnamate. The composite catalyst provided by the present invention has high reactivity and selectivity, a stable catalyst structure, and active ingredients are not easily lost, and the recycling of the catalyst can be achieved without frequent replacement of the catalyst. The operation is simple, and the operation is conducive to continuous industrial production, significantly improving equipment utilization. The use of the composite catalyst provided by the present invention can make the preparation of p-methoxycinnamate compounds react under relatively mild reaction conditions, without corrosion to the equipment, and without wastewater or waste salt generation, which is green and environmentally friendly.

The invention discloses a chiral alpha-aryloxy benzoxazole acetate compound and a synthesis method thereof, and the chiral alpha-aryloxy benzoxazole acetate compound is an optically active compound with a structure as shown in the following formula I, and comprises a stereoisomer with the same chemical general formula. According to the method, a complex formed by a chiral ligand and metal is used as a catalyst, an electrochemical catalysis asymmetric aryloxylation reaction is used as a key step, and the target chiral compound is accurately and efficiently synthesized with high yield and high stereoselectivity. The preparation method is simple, reaction conditions are mild, atom economy is excellent, and the prepared chiral alpha-aryloxy benzoxazole acetate compound has good biological activity potential, can be widely applied to the field of drug intermediate synthesis and has remarkable biomedical practicability and industrial large-scale production prospects.

The invention belongs to the technical field of medicine synthesis, and provides a preparation method of compounds as shown in formulas 5 and 2 and a preparation method of cannabidiol. The preparation method of the compound as shown in the formula 5 comprises the following steps: in the presence of an imide catalyst and a cocatalyst, oxidizing a compound as shown in a formula 4 by oxygen-containing gas to obtain a product containing the compound as shown in the formula 5; the co-catalyst is selected from at least one of an aldehyde compound, an acetic acid metal compound and an acetylacetone metal compound. According to the preparation method, the reaction efficiency can be remarkably improved and the production cost can be reduced under a milder oxidation condition.

The invention discloses a catalyst component for olefin polymerization as well as a preparation method, a catalyst and application thereof, and relates to the technical field of olefin polymerization. The catalyst component for olefin polymerization comprises reaction products of the following components: a magnesium compound, an organic anhydride compound, an acetate compound, an alcohol compound, a titanium-containing compound and an internal electron donor, the molar ratio of the magnesium element in the magnesium compound to the organic acid anhydride compound to the acetate compound to the alcohol compound to the titanium-containing compound to the internal electron donor is 1: (0.03-1.0): (0.01-5): (0.1-10): (0.5-120): (0.01-1). According to the invention, when an organic anhydride compound, an acetate compound, an alcohol compound and the internal electron donor are introduced into an N-series polyolefin catalyst preparation system as a compound electron donor, spherical or sphere-like solid particles (solid catalyst components) containing magnesium and titanium can be prepared. The catalyst particles are high in polymerization activity and narrow in particle size distribution, and polyethylene powder with high bulk density can be obtained through polymerization. Under further preferable conditions, the powder obtained through polymerization is high in sphericity degree, high in molecular weight and good in fluidity.

The invention discloses a synthesis method of a chiral propargyl-containing alpha-fluoro-substituted pyridine acetate compound, which comprises the following steps: in an organic solvent, under the catalysis of a nickel / copper bimetallic system and in the presence of alkali, carrying out asymmetric propargylation reaction on an alpha-fluoro-substituted pyridine acetate compound I and a propargyl alcohol ester compound II to obtain the chiral propargyl-containing alpha-fluoro-substituted pyridine acetate compound with high yield. The chiral propargyl-containing alpha-fluoro-substituted pyridine acetate compound III is obtained through high enantiomer and diastereomer selectivity, and has good functional group tolerance; the nickel catalytic system is composed of metal nickel and a chiral ligand, and the chiral ligand has a structure as shown in a formula IV; the copper catalyst system is composed of a copper salt and a chiral ligand, and the chiral ligand has a structure as shown in a formula V.

An ethyl 2-[9-(2-hydroxypyridin-3-yl)-3,6-diphenyl-1,8-dioxo-3,4,9,10-tetrahydroacridine-10-yl]-acetate compound, its synthesis, and its use as an antimicrobial agent.

The invention belongs to the technical field of synthesis of organic compounds, and particularly relates to a synthesis method of an amino-protected fluorine-containing methyl crotonate compound. The fluorine-containing methyl butenoic acid ester compound can be obtained by reacting the fluorine-containing methyl butenoic acid ester compound with an amino-protected phosphoryl acetate compound in the presence of an organic solvent and a specific alkali, and the fluorine-containing methyl butenoic acid ester compound has the advantages of high yield, few steps, low cost and the like, and is suitable for industrial production.

The invention provides a catalyst component for olefin polymerization, a preparation method of the catalyst component, a catalyst and application of the catalyst component. The catalyst component comprises a magnesium compound, an organic anhydride compound, an acetate compound, an alcohol compound, a titanium-containing compound and a reaction product of an internal electron donor. The magnesium compound is a compound formed by dissolving magnesium halide in a solvent system containing an organic epoxy compound and an organic phosphorus compound. The catalyst particles are high in polymerization activity and narrow in particle size distribution, polyethylene powder which is high in stacking density, good in particle morphology, high in molecular weight and narrow in molecular weight distribution can be obtained through polymerization, and the requirement of an industrial production device for the catalyst is met.

The present invention relates to a copolymer containing, based on 100% by weight of the total weight of the copolymer, vinyl acetate monomer units of 15% by weight or less, acrylate monomer units of 10% by weight or more and 55% by weight or less, and acrylic acid monomer units bonded to one or more selected from the group consisting of alkali metals and acetate salt compounds containing alkali metals of 1% by weight or more and 10% by weight or less, a slurry composition containing the same, a separation membrane, and a secondary battery.

The invention belongs to the field of organic synthesis, and particularly relates to a synthesis method of a polysubstituted indole propionate derivative. According to the invention, an aryl acetate compound and a sulfonyl indole compound are used as raw materials, and an organic small molecule catalyst such as isothiourea is used for reaction to obtain the compound. The reaction raw materials are simple and easy to obtain, the reaction condition is mild, the operation is simple and convenient, the reaction time is short, and good diastereoselectivity and high yield are achieved; the defects and deficiencies of the existing synthesis method for preparing the polysubstituted indole propionate derivative in a noninvasive manner are overcome, and the method has the characteristics of high efficiency, simplicity, convenience and wide universality.

The invention belongs to the technical field of cellulose acetate preparation, and discloses cellulose monoacetate, cellulose diacetate or cellulose triacetate and a low-cost rapid preparation method thereof. The low-cost rapid preparation method of cellulose monoacetate, cellulose diacetate or cellulose triacetate comprises the following steps: adding a cellulose raw material, an alcohol substance, toluene and deionized water into zirconium oxide balls to obtain a prepared product, carrying out ball milling treatment on the prepared product under the protection of nitrogen, adjusting ball milling parameters to obtain a ball milling product with a low substitution degree or a high substitution degree, and carrying out high-speed ball milling on the ball milling product with the low substitution degree or the high substitution degree to obtain the cellulose monoacetate, cellulose diacetate or cellulose triacetate. Washing a ball-milled product, then performing vacuum drying to obtain carboxylated cellulose with low substitution degree or high substitution degree, sequentially adding the carboxylated cellulose with low substitution degree or high substitution degree into an alkaline aqueous solution and an acetate compound to perform transesterification, and sequentially performing washing, vacuum filtration and vacuum drying on a transesterification product to obtain carboxylated cellulose with low substitution degree or high substitution degree. The cellulose monoacetate, the cellulose diacetate or the cellulose triacetate is obtained; the production cost can be reduced, and the preparation efficiency is remarkably improved.

The invention is directed to a process to prepare aluminium diacetate chloride starting by reacting aluminium trichloride with an acetate compound in a solvent, wherein the acetate compound is alkali acetate and wherein the solvent is a mixture comprising an alcohol and an organic acetate, wherein the molar ratio of aluminium trichloride and the alkali acetate compound is between 1:1.5 and 1:3 and wherein a corresponding alkali chloride salt is obtained as a by-product.

This invention relates to a recycled raw material composition and its preparation method. The recycled raw material composition comprises recycled bis(2-hydroxyethyl) terephthalate formed by the depolymerization of waste polyester, wherein the peak area ratio of acetate compounds is 1.0% or less when analyzed by high performance liquid chromatography (HPLC). Due to the reduced impurity content, this recycled raw material composition can exhibit high purity and high quality.

The invention discloses a fluoride-free water repellent synthesized based on an acrylic acid docosyl ester compound. The fluoride-free water repellent is prepared by the following steps: step 1, emulsifying the acrylic acid docosyl ester compound, a functional acrylic monomer, a polar olefin compound, a thiol compound, an acetate compound, a surfactant and water; 2, introducing inert gas into the reactant emulsion, heating to a reaction temperature, adding an initiator, and reacting for a preset time to obtain a fluoride-free water repellent emulsion; and the docosyl acrylate compound is docosyl acrylate or docosyl methacrylate. The water repellent is synthesized by adopting the docosyl acrylate compound as a main monomer, the fluorine-free water repellent emulsion synthesized by adopting an emulsion polymerization method has the solid content of more than 30%, and the fluorine-free water repellent emulsion has excellent storage stability and more excellent hydrophobicity and water repellency.

A cleaning composition includes an alkanol having 1 to 6 carbon atoms, an acetate compound and water. A content of water may be 50 wt % to 95 wt % based on a total weight of the cleaning composition. In a method of forming a photoresist pattern, a photoresist film is formed on a substrate, the photoresist film is partially removed to form a photoresist pattern, and the substrate on which the photoresist pattern is formed is cleaned using the cleaning composition.

The invention discloses a synthesis method of a hexadecatrienol acetate compound and application of the hexadecatrienol acetate compound as a conopomorpha sinensis sex pheromone attractant. By adopting a convergent synthesis strategy, two key pheromone compounds, namely 4-trans, 6-cis, 10-cis-hexadecatrienol acetate and 4-trans, 6-cis, 10-cis-hexadecatrienol acetate, are successfully prepared, so that not only is the synthesis efficiency remarkably improved, but also the characteristics of greenness and cleanness are achieved; the invention also provides an application of the hexadecatrienol acetate compound as a sex pheromone attractant for conopomorpha sinensis, and the hexadecatrienol acetate compound can be effectively used for monitoring and green prevention and control of conopomorpha sinensis, so that the use of chemical pesticides is reduced, and the quality safety of fruits and the sustainable development of the ecological environment are guaranteed.

Described herein are methods for the acetyl transferase-catalyzed production of drimanyl-acetate compounds by the acetylation of the respective drimanyl alcohol sources performed in vitro or in vivo. Also described herein is the identification of enzymes having corresponding acetyl transferase activity from different microbial and plant sources. Also described herein is the provision of enzyme mutants derived from the newly identified enzymes. Further described herein is the provision of corresponding coding sequences of such enzymes and mutants, recombinant vectors, and recombinant host cells suitable for the production of such acetyl transferases and mutants and for performing the novel production methods of drimanyl acetate compounds. Still further described herein is a method of using such drimanyl acetates as intermediates for the production of odorant, flavor or fragrance or insect / pest control ingredients.

The present invention belongs to the field of catalyst technology and discloses a catalyst component for ethylene polymerization, its preparation method, catalyst, and application. The catalyst component comprises the reaction product of the following components: 1) a spherical or quasi-spherical solid catalyst component B; 2) an alcohol compound; 3) a second organic epoxy compound; and 4) a second titanium compound. The spherical or quasi-spherical solid catalyst component B comprises the reaction product of a magnesium complex, an organic anhydride compound, an acetate compound, and the first titanium compound. The catalyst exhibits high polymerization activity and hydrogen modulation sensitivity for ethylene polymerization.

The application belongs to the technical field of medicine, and particularly relates to a styrene acetate compound, a preparation method and application thereof. The application provides a styrene acetate compound with a structure shown in formula 1. The styrene acetate compound with the structure shown in formula 1 provided by the application can play a role of inhibiting RAC1 activity by being combined with RAC1 protein, and is suitable for treating diseases related to RAC1 protein, including Alzheimer's disease, atherosclerosis, tumor cell migration and tumor cell invasion, etc. The results of the examples also show that the styrene acetate compound with the structure shown in formula 1 provided by the application can significantly inhibit the formation of cytoskeleton of tumor cells such as breast cancer and gastric cancer, thereby playing a role of inhibiting the migration and invasion activity of tumor cells.

The invention belongs to the field of organic chemistry and biosynthesis, and particularly relates to a specific high-activity hydrolase, a gene, an engineering bacterium and application, the specific high-activity hydrolase is obtained by mutation of an original hydrolase, the sequence of the original hydrolase is SEQ ID NO.1, the mutation is as follows: the 160th site is mutated from A to D, the 254th site is mutated from V to S, or the 160th site is mutated from A to D, and the 254th site is mutated from V to S; the 160th site is mutated from A to D, and the 254th site is mutated from V to S; the method is used for catalyzing hydrolysis of a substrate, and the substrate is a steroid 21-hydroxy acetate compound; the conversion condition is mild, and no organic solvent needs to be added; the conversion specificity is high, and no by-product is generated; and the product purity and yield are high.

The invention relates to a catalyst component for olefin polymerization, a preparation method of the catalyst component, a catalyst and application of the catalyst component. The catalyst component for olefin polymerization comprises reaction products of the following components: a magnesium compound, an organic anhydride compound, an acetate compound, a first alcohol compound, a titanium-containing compound and an organosilicon compound, the magnesium compound is a compound formed by dissolving magnesium halide in a solvent system containing an organic epoxy compound and an organic phosphorus compound. According to the present invention, the performance of the existing Ziegler-Natta type olefin polymerization catalyst particle is improved through the simple raw materials, the cost is low, and the prepared catalyst component is spherical / sphere-like, has advantages of excellent polymerization activity, excellent hydrogen regulation sensitivity, excellent stacking density, excellent particle size distribution, excellent viscosity average molecular weight, and extremely high promotion and application values.

The invention relates to a catalyst component for olefin polymerization, a preparation method of the catalyst component, a catalyst and application of the catalyst component. The catalyst component comprises a reaction product of a magnesium compound, an organic anhydride compound, an acetate compound, a first alcohol compound, a titanium-containing compound and an organosilicon compound, the general formula of the organic silicon compound is R1aR2b (OR3) cSi-M-Si (OR3 ') dR1'eR2'f. According to the invention, the performance of the existing Ziegler-Natta type olefin polymerization catalyst particles is improved, and the prepared catalyst component is spherical / sphere-like, has better polymerization activity, hydrogen regulation sensitivity, stacking density, particle size distribution and fluidity, and has extremely high popularization and application values.

The present invention provides a trans-trans dioxime acetate compound having the structure shown in Formula I: where, in Formula I, the symbol E indicates that the O-N bond distribution in the oxime group is trans; R1 is selected from C1-C6 alkyl, C1-C2 alkylene substituted with C5-C7 cycloalkyl, and ethylene substituted with C1-C4 alkoxy; R2 and R2' are each independently selected from C1-C7 alkyl, C1-C2 alkylene substituted with C5-C7 cycloalkyl, and C5-C7 cycloalkyl. The compound of the present invention exhibits high sensitivity performance in photocurable composition formulations, especially in photoresists, with performance markedly superior to that of the existing technology.

The application discloses a method for catalytically synthesizing optically pure (S)-alpha-fluorophenylacetate compounds by P450 enzymes and belongs to the technical field of biological catalysis and chiral synthesis. In view of the problem that (S)-configuration fluorine-containing compounds are difficult to synthesize, the method uses alpha-fluorophenylacetate derivatives as substrates, uses a P450 BM3 mutant (F87V-L188G-R47L-Y51F) obtained through directional evolution as a catalyst, and performs an oxidative defluorination reaction in the presence of a coenzyme regeneration system to obtain a target product through kinetic resolution. The optically pure (S)-alpha-fluorophenylacetate compound has an optical purity ee>96% and can be used for preparing chiral fluorine-containing medical intermediates.