76results about How to "No metal residue" patented technology

The invention discloses a preparation method of polyene ether compounds. The method includes: organic small-molecule 4-dimethylamino pyridine (DMAP) is used as the catalyst, binary alkynyl compounds and binary hydroxy compounds are mixed with organic solvent, and the polyene ether compounds are obtained by using the click polymerization reaction of alkynyl-hydroxy. The polyene ether compounds comprise an inner unit indicated by formula (I). The polymerization step is showed in the formula (V), wherein n is larger than 1, and R1 and R2 are selected from organic groups. The method has the advantages that water and oxygen do not need to be removed during reaction, polymerization temperature is low, polymerization efficiency is high, and no metal residues exist in products; the prepared polyene ether compounds are high in steric regularity, good in machinability, and high in heat stability, degradability and aggregation-induced emission performance.

The invention discloses a 3, 3'-disubstituted 3-pyrrole oxoindole compound and an asymmetric synthetic method thereof and belongs to the fields of organic chemistry and medicines. The structure of the compound takes the 3, 3'-disubstituted 3-pyrrole oxoindole compound as a framework, and the type of indole alkaloid is enriched so as to provide a sufficient compound source for screening pharmaceutical activity. Meanwhile, a synthetic method of the compound is provided. The asymmetric synthetic method comprises the following steps: dissolving 3-pyrrole oxoindole, an electrophilic reagent and a chiral catalyst in an organic solvent; carrying out a reaction at (-20)-25 DEG C; after reaction, separating and purifying to obtain the compound. The method is mild in reaction condition, easy in obtaining of raw materials and catalyst, free from metal residues, simple to operate, high in yield and further high in stereoselectivity.

The invention discloses a method for cyclic compound ring opening polymerization and belongs to the technical field of organic catalytic and high polymer materials. According to the method disclosed by the invention, a cyclopropene salt is utilized to catalyze cyclic compound ring opening polymerization in the presence of an initiator to obtain polyester compounds. By means of the method disclosed by the invention, a macromolecular biodegradable material with large molecular weight, narrow dispersity and no metallic impurities can be obtained. A novel catalyst system is stable and general and is effective for a long time in a storage aspect. The macromolecular material prepared by the method can be applied to aspects of medicine carriers, nano reactors, films, material connectors and the like, further has biodegradability and is an environment-friendly material.

The invention discloses a method for preparing polylactone, and relates to the technical field of polymer materials. An initiator alcohol or amine is used to initiate ring opening of a cyclic lactonemonomer or a cyclic lactide monomer or a cyclic carbonate monomer, ring-opening polymerization of a small molecule monomer is initiated under the catalysis of an organic catalyst to obtain polylactone, and the organic catalyst is a hydantoin derivative and tertiary amine catalyst system. The method has the advantages of high catalytic efficiency, mild reaction, and high-efficiency synthesis of pure polylactone, and the product has the advantages of no metal residue, narrow molecular weight distribution, high product yield, no monomer residue and white color.

The invention belongs to the technical field of green catalytic synthesis, and particularly relates to a preparation method of cyclic carbonate. Epoxide and carbon dioxide are catalyzed by using a catalyst provided by the invention to obtain the cyclic carbonate. According to the invention, the synthesis method is simple, cost is low, the catalyst has high activity and high selectivity, a reactioncondition is mild, and good reusability is realized.

The invention belongs to the field of organic synthesis, fine chemicals and daily chemicals, and particularly relates to a synthetic method of hydroxypropyl tetrahydropyrantriol catalyzed by a biological enzyme. According to the method, a double-enzyme circulating catalysis system containing aldoketo reductase (AKR) and ethanol dehydrogenase (ADH) is used, and in the presence of oxidized coenzyme II (NADP), isopropanol is used as a reducing agent, so that the synthesis of the hydroxypropyl tetrahydropyrantriol is realized. As biological enzyme catalysis is adopted, the method is mild in condition, simple and convenient to operate, small in pollution, green, safe, free of metal residues and high in product purity, and is particularly suitable for synthesis of active matters of medicines and cosmetics.

The invention belongs to the technical field of organic chemistry and photocatalysis and discloses a method for synthesizing 3,4-dihydroisoquinoline by semi-dehydrogenation oxidation of 1,2,3,4-tetrahydroisoquinoline. According to the method, by adoption of MoS2/ZnIn2S4 as a photocatalyst, semi-dehydrogenation oxidation of 1,2,3,4-tetrahydroisoquinoline is realized in an N2 atmosphere under the visible light condition to obtain a product namely 3,4-dihydroisoquinoline, and high conversion rate and selectivity are achieved. In addition, the method is simple, convenient and feasible and is beneficial to large-scale industrial popularization.

The invention discloses a method for preparing polylactone through ring-opening polymerization and belongs to the high-molecular material synthesis field. The preparation method is as follows: in presence of an organic sulfonic acid catalyst in an organic solvent, lactone is employed as reaction monomers, a reaction is carried out with organic alcohol as an initiator, the monomers are subjected to ring-opening polymerization, and polylactone prepared. The organic sulfonic acid is 2,4-Dinitrobenzenesulfonic acid. The polylactone prepared through catalysis of organic sulfonic acid has no metal residues, restriction of medical material aspect applications is avoided, and the high-efficiency polymerization reaction without high temperature shows green low energy consumption.

The invention belongs to the field of organic synthesis, and particularly relates to a method for synthesizing cyclic carbonate and derivatives thereof, which comprises the following step of: reactingan epoxy compound shown in a formula I with carbon dioxide under the catalysis of a catalyst shown in a formula II to obtain a target product. The product prepared by the method has the advantages ofhigh yield, high purity, low catalyst cost and mild synthesis conditions, and the obtained product has no metal residue.

The invention provides a high-conductivity metal electrode patch production method. The method includes: selecting a support substrate with at least the surface layer being nitride, and subjecting the support substrate to polishing treatment or surface hydrophilia treatment. The substrate comprises a silicon wafer or refractory ceramics; the silicon wafer comprises a monocrystalline silicon wafer or polycrystalline silicon wafer, and the refractory ceramics comprise oxide-free nitrogen ceramics and oxide ceramics. The suitable materials are selected, a method combining surface coating and surface treatment is utilized, binding force between the electrode and the substrate is lowered greatly, the electrode can be stripped directly with adhesive tape, the stripped surface is quite smooth, and no metal residual is left on the substrate. No organic solution process is related, electrode patches with shapes unlimited can be formed, and the shortcomings of complex procedures and low electric conductivity due to the fact that the electrode is produced on a device directly are overcome.

The invention discloses a synthetic method of gradient polyester. The invention belongs to the field of polymer synthetic materials. The invention aims to solve the technical problems of lack of research on chirality of a polymer chain and difficulty in synthesis and characterization in research on a chiral polymer in the prior art. The synthetic method of the gradient polyester comprises the following steps: under normal pressure and inert gas protection, in an organic solvent, racemic substituted lactone is used as a polymeric monomer, chiral phosphoric acid is used as a catalyst, and an alcohol compound is used as an initiator; and ring-opening resolution polymerization is realized by utilizing the difference of the reaction rates of two enantiomers in the polymeric monomer, so that the gradient polyester is obtained. According to the asymmetric resolution polymerization method for racemic substituted lactone, novel polyester with a gradient structure can be obtained, the types and application fields of polyester materials are expanded, and development of chiral polymer functional materials is promoted. The method is simple and convenient to operate, mild in condition and controllable in polymerization activity, and the generated polymer is free of metal residues.

The invention discloses a method for preparing quinazolone and derivatives thereof by using a chitosan-loaded copper catalyst, which comprises the following steps of replacing residual gas in a reaction container with inert gas, adding a catalytic amount of copper ion-loaded chitosan catalyst, substituted 2-halogenated benzoic acid, substituted amidine hydrochloride, inorganic alkali and a mixed solvent into the reaction container, and heating for reaction, after the reaction time is 2-18 hours, extracting the product by using ethyl acetate, filtering and recovering the copper ion-loaded chitosan catalyst, concentrating the filtrate under reduced pressure, and purifying the product by column chromatography. The method has the advantages of low catalyst dosage, recoverability, easy separation after reaction, no metal residue, simple post-treatment, and suitableness for large-scale production.

The invention belongs to the technical field of biodegradable materials, and particularly relates to a preparation method of hydrolysis-resistant hyperbranched polycaprolactone. The preparation method comprises the steps of (1) mixing a hydroxyl-containing compound with a phosphazene catalyst, and then reacting with an epoxy compound to prepare hyperbranched polyether polyol; and (2) taking the hyperbranched polyether polyol as a macromolecular initiator, and continuously initiating a ring-opening polymerization reaction of caprolactone under the action of a phosphazene catalyst to prepare the hyperbranched polycaprolactone. The synthesis process is simple, the reaction activity is controllable, the prepared hyperbranched polycaprolactone has the advantages of no metal residue, excellent processability, controllable branching degree and hydrolysis resistance, and the application of the polycaprolactone material in the biomedical field is further widened.

The invention belongs to the field of organic synthesis, and particularly relates to a ring-opening polymerization method of a cyclic monomer, which adopts the specific scheme that ring-opening polymerization of the cyclic monomer is catalyzed by Lewis acid-base pairs in the presence of an initiator. Lewis acid-base pairs are used as a catalyst; on one hand, the range of the ring-opening polymerization catalyst is expanded; on the other hand, compared with a strong acid or strong alkali catalyst reported before, the catalyst has the characteristics of high catalytic efficiency and mildness, and the catalytic system activates the monomer and activates the initiator or chain end at the same time through a bifunctional activation mechanism, and has the characteristic of high efficiency compared with a reported monomer activation mechanism or chain end activation mechanism. By adopting the catalyst, the polyester product with the target molecular weight can be synthesized in a controlled manner as required, the molecular weight distribution index is relatively narrow, the product yield is high, the product conversion rate is high, and no monomer or metal residue exists.

An environment-friendly flocculant and application thereof belong to the technical field of environment-friendly flocculants. At present, the most widely applied flocculants are mainly inorganic flocculants (such as polyaluminum chloride) and synthetic organic flocculants (such as polyacrylamide), the flocculants have certain toxicity and are difficult to degrade, secondary pollution can be caused when the flocculants are widely used, and waste residues cannot be treated. The invention provides an environment-friendly flocculating agent which is non-toxic, harmless, free of secondary pollution and good in performance and application of the environment-friendly flocculating agent. The main component of the environment-friendly flocculating agent is a dextran-citric acid anionic polymer. The preparation method comprises the following steps of: adjusting the pH value of a citric acid solution to 7-9 by using sodium hydroxide, well mixing and stirring the citric acid solution with a dextran solution, adding 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, and reacting for 12-36 hours, the molar ratio of edc to citric acid being (1-2): 1; and adding ethanol for precipitation, and washing and drying the precipitate to obtain the flocculant. Soybean meal waste liquid can be used for livestock breeding after being flocculated, the preparation is simple, and the efficiency is high.

The invention discloses a method for synthesizing a five-membered oxygen-containing heterocyclic compound, which is characterized in that epoxide and hetero-accumulated diene are used as raw materials, and the five-membered oxygen-containing heterocyclic compound is obtained by reaction with a catalyst of formula I provided by the invention. Reagents used in the method are cheap and easy to obtain, the product can be synthesized through a one-step method, conditions are mild, no metal residues exist in the whole reaction system, no by-products are generated, and a single product is obtained with high selectivity.