73results about How to "Has aggregation-induced luminescent properties" patented technology

A low-power white-light-driven mitochondrial-targeting fluorescent probe photosensitizer as well as a synthesis method and application thereof are disclosed. The molecular formula of the photosensitizer is shown in the description, and is short for AIE-FR-TPP. The photosensitizer has the advantages that the photosensitizer has aggregation-induced luminescence characteristics and zebrafish mitochondrial targeting characteristics, generates reactive oxygen for photodynamic therapy under low-power white light irradiation, and can monitor the morphological changes of zebrafish mitochondria on reactive oxygen species damage in real time, and is taken as a favorable research tool for real-time monitoring of zebrafish mitochondrial fluorescence imaging and photodynamic therapy. The probe photosensitizer not only has zebrafish mitochondria specific imaging capabilities and photodynamic therapy properties, but also can monitor mitochondrial reactive oxygen species damage in situ in real time.

The present invention discloses an aggregation induced luminescence nanofluorescent probe which coats a chitosan fluorescent molecule with the characteristic of aggregation induced luminescence on the surface of a hydroxyl apatite nanoparticle, and the structural formula of the chitosan fluorescent molecule is shown in a formula (1). The aggregation induced luminescence nanofluorescent probe is prepared by a chemical co-precipitation process. The size of the aggregation induced luminescence nanofluorescent probe is about 110 nm, the dispersion is stable, positive changes are formed on the surface thereof, and the aggregation induced luminescence nanofluorescent probe has the feature of the aggregation induced luminescence. Compared with a traditional fluorescent probe, the aggregation induced luminescence nanofluorescent probe has the advantages that the sensitivity is high, the light stability is good, and quenching does not exist during high concentration and a fluorescence spectrum is not drifted, so that the aggregation induced luminescence nanofluorescent probe can be applied to the fields of bioimaging, fluorescent tracing detection and the like. The aggregation induced luminescence nanofluorescent probe is shown in the figure below.

The invention discloses a copper (I) alkyne cluster with aggregation-induced luminescence and circularly polarized luminescence, which belongs to the cross field of coordination chemistry and nanometer materials. The enantiomer of the chiral nano-copper cluster uses the chiral ligand (R / S)-2-diphenyl-hydroxymethylpyrrolidine-1-propyne (R / S-DPM) as a protective ligand, through a simple It is synthesized by room temperature volatilization in one pot, with high yield and excellent luminescent properties. The chemical formula of this enantiomeric cluster is: C 160 h 160 P 6 Cu 14 f 36 o 8 (Abbreviated as: R / S‑DPM‑Cu 14 ), belongs to the orthorhombic crystal system, and the space group is the chiral space group P 2 1 2 1 2 1 . The copper nanocluster has red fluorescence at room temperature; its chiral structure and luminescent properties endow the cluster with strong circularly polarized luminescence (CPL) properties, which makes it very good in luminescent materials and chiral optical materials. Application prospects; the copper nanocluster has aggregation-induced emission (AIE) properties, and its fluorescence increases with the increase of poor solvent content, and realizes strong circularly polarized luminescence (CPL) properties, and its fluorescence asymmetry factor reaches 1.0× 10 ‑2 , its aggregation-induced luminescent properties, ultra-small size and low toxicity can be used for bright cell imaging.