73results about How to "Has aggregation-induced luminescent properties" patented technology

The invention belongs to the technical field of organic photoelectric materials, and discloses a tetraphenylethylene-containing organic semiconductor material and a preparation method thereof, and application of the material in organic photoelectric devices. The tetraphenylethylene-containing organic semiconductor material is disclosed as Formula I or II, wherein R1, R2, R3, R4 and R5 can be identical or different aromatic ring derivative groups. Different modification groups can be connected to the tetraphenylethylene to regulate the electronic or hole transmission performance of the tetraphenylethylene derivatives, so that the organic semiconductor material not only can be used as a luminescent layer, but also can be used as a luminescent layer and current carrier transmission layer, thereby obtaining the electroluminescent devices with favorable photoelectric properties, simple structure and low cost; and the organic semiconductor material has wide application prospects in the fields of organic electroluminescence, organic field-effect transistors, organic solar cells and other organic electronics.

The invention discloses a luminescent material having aggregation-induced emission, a method of making and an application thereof. The luminescent material herein has properties of aggregation-induced emission/aggregation-enhanced emission with the maximum absorption wavelength red shift to a visible area so that this type of luminescent material has potential applications in the field of biology. The luminescent material allows the formation of transfer of electric charges in a molecule and exhibits strong polar dependent emission in different solvents. The luminescent material does not emit due to strong dipoalr interaction in a molecule, but emits in a weak-polar environment with a cell. The luminescent material can serve as intracellular lipid droplet and intramicroalgae lipid droplet, and has the advantages of high selectivity, high emission stability and high biological compatibility.

The invention discloses a preparation method of polyene ether compounds. The method includes: organic small-molecule 4-dimethylamino pyridine (DMAP) is used as the catalyst, binary alkynyl compounds and binary hydroxy compounds are mixed with organic solvent, and the polyene ether compounds are obtained by using the click polymerization reaction of alkynyl-hydroxy. The polyene ether compounds comprise an inner unit indicated by formula (I). The polymerization step is showed in the formula (V), wherein n is larger than 1, and R1 and R2 are selected from organic groups. The method has the advantages that water and oxygen do not need to be removed during reaction, polymerization temperature is low, polymerization efficiency is high, and no metal residues exist in products; the prepared polyene ether compounds are high in steric regularity, good in machinability, and high in heat stability, degradability and aggregation-induced emission performance.

The invention discloses a tetravinyl-based Gemini type amphiphilic compound as well as a preparation method and application thereof. The compound disclosed by the invention is mainly prepared through McMurry coupling reaction, nucleophilic substitution reaction and Click reaction; the structure of the compound is also confirmed through infrared, nuclear magnetic and mass-spectrum ways; in an aqueous solution, molecules of a derivative of the compound disclosed by the invention self-assemble to form aggregation-induced fluorescence-enhanced micelles (AIE micelles); the compound acts with a nucleic acid, and then can co-aggregate to form nano particles easy for cellular uptake; green fluorescent protein (GFP) and luciferase (Luciferase) expression assays prove that the compound self and a liposome formed with dioleoyl phosphatidyl ethanolamine (DOPE) can be used as non-viral gene vectors; meanwhile, the derivative is successfully used for tracing the cellular uptake and release processes of pGL-3 and FAM-DNA by utilizing the reversible transformation between the self-assembly of the compound and the co-assembly with DNA (Deoxyribonucleic Acid).

The invention discloses an aggregation-induced emission type diarylethene fluorescent molecular switch and a preparation method and application thereof. The aggregation-induced emission type diarylethene fluorescent molecular switch is characterized in that an AIE radical is introduced to gain solid or aggregation strong emission capacity; two diarylethene can be used for quickly quenching fluorescence of fluorescent radicals which aggregate in the surrounding under the irradiation of ultraviolet rays or visible light, thus achieving the purpose of high fluorescent switch ratio. According to the light control type AIE-effect fluorescent molecular switch, the limitation that traditional fluorescent chromophore leads to fluorescence quenching is broken; in addition, the fluorescent molecularswitch in solid and aggregation state has the advantages of being high in switch ratio and high in fluorescence quenching efficiency by being compared with the fluorescent molecular switch in solution state; the fluorescent molecular switch is applicable to information storage under solid state and photoelectric devices and has potential application in biosensing and fluorescence imaging.

The invention discloses a pyridine-triphenylamine-anthracene conjugated molecule with an aggregation-induced emission property and a preparation method thereof. The conjugated molecule comprises a pyridine group, a triphenylamine group and an anthracene group at a ratio of 4:2:1. The pyridine-triphenylamine-anthracene conjugated molecule emits red light in solid state, and emits green fluorescence in a tetrahydrofuran dilute solution; in the mixed solvent of water and tetrahydrofuran, the emission wavelength of aggregative state nono particles covers the broadband from green light to yellow light along with the increase of content of poor solvent water. The pyridine-triphenylamine-anthracene conjugated molecule has the aggregation-induced emission property.

The present invention discloses an aggregation induced luminescence nanofluorescent probe which coats a chitosan fluorescent molecule with the characteristic of aggregation induced luminescence on the surface of a hydroxyl apatite nanoparticle, and the structural formula of the chitosan fluorescent molecule is shown in a formula (1). The aggregation induced luminescence nanofluorescent probe is prepared by a chemical co-precipitation process. The size of the aggregation induced luminescence nanofluorescent probe is about 110 nm, the dispersion is stable, positive changes are formed on the surface thereof, and the aggregation induced luminescence nanofluorescent probe has the feature of the aggregation induced luminescence. Compared with a traditional fluorescent probe, the aggregation induced luminescence nanofluorescent probe has the advantages that the sensitivity is high, the light stability is good, and quenching does not exist during high concentration and a fluorescence spectrum is not drifted, so that the aggregation induced luminescence nanofluorescent probe can be applied to the fields of bioimaging, fluorescent tracing detection and the like. The aggregation induced luminescence nanofluorescent probe is shown in the figure below.

The invention discloses a fluorescent probe for rapidly responding to hydrogen peroxide as well as a preparation method and application thereof. The structural formula of the fluorescent probe is shown in the specification. A raw material TPE-Br and bis(pinacolato)diboron are dissolved in a solvent, a reaction is carried out under a heating condition with a catalyst, the probe is obtained, and the probe is named TPE-BO. The probe molecule has an aggregation-induced emission property, and response time between the fluorescent probe and hydrogen peroxide is effectively reduced by 10 minutes. The dyeing effect for living cells is good, the dyeing time is short, and the dyeing efficiency is high. The synthesis steps are relatively simple, the yield is high and purification is easy.

A low-power white-light-driven mitochondrial-targeting fluorescent probe photosensitizer as well as a synthesis method and application thereof are disclosed. The molecular formula of the photosensitizer is shown in the description, and is short for AIE-FR-TPP. The photosensitizer has the advantages that the photosensitizer has aggregation-induced luminescence characteristics and zebrafish mitochondrial targeting characteristics, generates reactive oxygen for photodynamic therapy under low-power white light irradiation, and can monitor the morphological changes of zebrafish mitochondria on reactive oxygen species damage in real time, and is taken as a favorable research tool for real-time monitoring of zebrafish mitochondrial fluorescence imaging and photodynamic therapy. The probe photosensitizer not only has zebrafish mitochondria specific imaging capabilities and photodynamic therapy properties, but also can monitor mitochondrial reactive oxygen species damage in situ in real time.

The invention discloses a quaternized chitosan fluorescent probe with the aggregation-induced emission property. A preparation method of the probe mainly comprises the steps that 2,3-glycidyl trimethyl ammonium chloride (GTA) is inoculated onto a chitosan chain to obtain quaternized chitosan (TMC) with excellent water solubility; tetraphenylethylene (TPE) fluorescent molecules are marked on TMC to obtain TPE-TMC with the aggregation-induced emission (AIE) property. The prepared fluorescent probe has the excellent water solubility and the aggregation-induced emission property, and has the advantages of being high in sensitivity and good in light stability and not drifting in fluorescence spectrum compared with a traditional fluorescent probe. In addition, due to the intrinsic property of quaternized chitosan, and the probe has a positive charge, has the good water solubility and biocompatibility, and is expected to be used for the fields of periodic cell tracing, pathological monitoring, drug metabolism detection and the like.

The invention discloses an Hg2+ detecting aggregation-induced emission type fluorescent sensor and a production method and application thereof. The structural formula of the fluorescent sensor is as shown in specification. The fluorescent sensor is of aggregation-induced emission property and is nonluminous in solution, and its fluorescent light is enhanced in an aggregation state, accordingly, the fluorescent sensor can be applied to recognition of highly specific selectivity and anti-interference performance of Hg2+. Besides, the fluorescent sensor has high biocompatibility and cellular permeability, can target mitochondria in cells and light the Hg2+ in mitochondria by fluorescent light, and accordingly can realize detection of Hg2+ in the mitochondria.

The invention discloses a carboxylation chitosan nano-fluorescence probe with aggregation-induced emission characteristic. A preparation method of the probe comprises the following main steps: labeling tetraphenylethylene fluorescence molecule (TPE) to a carboxylation chitosan chain (NCS) to obtain TPE-NCS with aggregation-induced emission (AIE) characteristic; and using sodium polyphosphate by an ion-crosslinking method to prepare TPE-NCS nanoparticles. The prepared nano-fluorescence probe has good dispersity in an aqueous solution, and has aggregation-induced emission characteristic. In comparison with a traditional fluorescence probe, the nano-fluorescence probe has advantages of high sensitivity, good light stability, no fluorescence spectra shift, stable and uniform nanoparticle size, easy storage and the like. Due to inherent characteristics of carboxylation chitosan, the probe of the invention has good biocompatibility, long retention of body circulation and good dispersity within a wide pH range, and could be used in fields of long-period cell tracking, pathological monitoring, drug metabolism detection, etc.

The invention relates to a sound-sensitive agent with aggregation-induced emission characteristics and a preparation method thereof. The sound-sensitive agent has a core-shell structure: the inner core is fluorophore molecules with aggregation-induced emission characteristics, and the outer shell is a hydrophilic substance. The preparation method of the sound-sensitive agent comprises the following steps: 1) dissolving the fluorophore molecules with aggregation-induced emission characteristics in an organic solvent, then adding the hydrophilic substance, and uniformly mixing to obtain a mixedsolution; and 2) adding the mixed solution into water, stirring to form a core-shell structure, and separating to obtain the sound-sensitive agent with aggregation-induced emission characteristics. Compared with the prior art, the prepared sound-sensitive agent has no fluorescence quenching effect, so that more singlet oxygen can be generated in the sonodynamic therapy process to inhibit tumor growth; due to the characteristics of the AIE molecules, fluorescence navigation interventional therapy can be introduced; meanwhile, the AIE molecules are various in variety, so that the range of the sound-sensitive agent can be expanded.

The invention relates to the technical field of photochemical detection and analysis, and discloses a fluorescent compound for detecting viscosity of oil displacement of tertiary oil recovery, and a preparation method and application of the fluorescent compound. The fluorescent probe is 2-(4-bis(4-methoxyphenyl)amino)phenyl)anthracene-9,10-dione (TPAMD). The probe compound disclosed by the invention is composed of groups with an aggregation-induced emission characteristic and anthraquinone groups with an electron-withdrawing effect, and thus has an aggregation-induced emission characteristic and an intramolecular charge transfer characteristic simultaneously. The probe is easy to prepare, is high in yield, has good viscosity responsiveness, and has relatively good linear response. The probe can be used in complex solvent environments, has good resistance to solvent perturbation, can be used to achieve detection of viscosity of chemical displacement agents in the oil production field, and the method has an analysis and detection potential for various viscosity-sensitive fields such as chemistry, food, environment and the like.

The invention provides an aminohexose enzyme fluorescent probe and a preparation method and application thereof, and relates to the field of biochemical materials. The aminohexose enzyme fluorescent probe provided by the invention has a structure as shown in a formula I. The aminohexose enzyme fluorescent probe has the advantages of few synthesis steps, simple separation and purification operationand good stability, has aggregation induced luminescence characteristic and strong photobleaching resistance, avoids the defect that traditional fluorescent dye is not suitable for detection at highconcentration or cannot be tracked for a long time due to fluorescence quenching caused by aggregation after entering cells, and can be applied to detection of over-expressed aminohexose enzyme in cancer cells.

The invention discloses a hyperbranched polymer and a preparation method and application thereof, and belongs to the technical field of high polymer materials. The hyperbranched polymer comprises a structural unit with a structural formula shown as a formula (I). The preparation method comprises the following steps: carrying out Barbier polycondensation reaction on a mixture containing a reactionmonomer, metal and an initiator at the temperature of 10-100 DEG C in an inert atmosphere, and hydrolyzing. The hyperbranched polymer has the aggregation-induced emission property, and the preparationmethod of the hyperbranched polymer is simple in process, mild in condition, high in operability, low in cost, non-toxic and harmless. The hyperbranched polymer has emission in a yellow fluorescent region, and a white light LED is obtained by converting a blue light wafer.

The invention discloses an assembly adjustment fluorescence enhancement aggregation-induced emission material, a micro-nano sphere, a preparation method and application. The molecular formula of the luminescent material is formula I. The material disclosed by the invention is stable in structure, has aggregation-induced emission and mechanochromic properties, and is good in luminescence property, the powder state fluorescence quantum yield can reach 45.5%, and the powder fluorescence quantum yield after grinding can reach 65.6%; by adopting an aggregation method in an evaporation solvent and a poor solvent, the luminescent material can be prepared into micro-nano spheres with different sizes through self-assembly, and the fluorescence quantum yield of the nano-scale spherical assembly can reach 85.3%; the synthesis and preparation method of the aggregation-induced emission material is simple to operate, mild in reaction condition and high in yield; the aggregation-induced emission material and the assembled micro-nano spheres are insoluble in water and most of organic solvents, have high fluorescence efficiency and mechanochromic performance, and can be used in the fields of counterfeiting prevention, real-time monitoring of pressure change, biological fluorescent probes, biological imaging and the like.

The invention discloses a tetraphenyl ethylene functionalized oligothiophene derivative and a preparation method thereof, and provides application of the oligothiophene derivative in detection of nitroaromatic explosives. The oligothiophene derivative prepared by the method is low in cost, good in crystallinity and beneficial to purification, and the structure of the oligothiophene derivative is characterized by 1H NMR. Along with the increase of the concentration of a nitroaromatic compound solution, the fluorescence intensity of the oligothiophene derivative is gradually quenched, and the quenching percentage is as high as 98% or above. The sensing test paper prepared by the method of natural air drying after soaking can quantitatively detect explosives such as nitrobenzene, dinitrobenzene, picric acid and the like. Reliable technical support is provided for rapid, cheap and visual detection of explosives.

The invention relates to an aggregation-induced luminescent polyphosphate and a synthesis method thereof. The hydroxyl-terminated hyperbranched polyphosphate or linear polyphosphate is obtained by reacting a phosphate or phosphite with a dihydric alcohol or a trihydric alcohol according to a certain molar ratio through a simple ester exchange polycondensation method. The synthesized polyphosphatecan emit bright blue fluorescence under irradiation of ultraviolet light. Under irradiation of light with different wavelengths, fluorescent light with different wavelengths can be emitted, and the fluorescent light emitted by the synthesized polyphosphate can cover almost the whole range of visible light. The synthesized hyperbranched polyphosphate has a property of delaying fluorescence, and thefluorescence lifetime reaches a microsecond level. The synthesized hyperbranched polyphosphate has an aggregation-induced luminescence characteristic. The method has the characteristics of simple process, controllable structure, no need of solvents, environmental friendliness and the like. The synthesized polyphosphate has good biocompatibility, biodegradability, easy modification and the original aggregation-induced luminescence characteristic, so that the synthesized polyphosphate has wide application prospects in the aspects of DNA/RNA transport, cell imaging, drug delivery and the like.

The invention discloses a preparation method of near-infrared fluorescent molecules with aggregation-induced emission characteristics. The molecular formula of the compound is shown in the specification. The invention discloses a preparation method and application of the solid-state near-infrared fluorescence emission molecule. The compound disclosed by the invention has the characteristic of aggregation-induced emission, the unique chemical structure of the compound enables the compound to emit near-infrared light, and the solid-state maximum fluorescence peak position is 770nm. Therefore, the molecule has a wide application prospect.

The invention provides a naphthalimide compound with an active end and a preparation method and application thereof. The naphthalimide compound takes 1, 8-naphthalimide as an electron withdrawing body and 9, 9-dimethyl fluorene as an electron donor, the compound has aggregation-induced emission performance by changing groups at molecular amide sites, and the structural formula of the naphthalimide compound is shown in the specification, wherein R is selected from phenols or amino alcohols, the series of compounds emit weak light in a solution, but show strong green fluorescence in an aggregation state, and show an obvious aggregation-induced emission property; meanwhile, the series of compounds show fluorescence with different colors in solvents with different polarities and have an obvious solvent effect; the structure of the series of compounds has a hydroxyl active end, a probe recognition unit, a subcellular localization unit and the like can be introduced through esterification and etherification reactions, expansion in the application fields of fluorescent probes, subcellular imaging and the like is achieved, and therefore the compounds can be used for cell imaging.