The invention discloses a carbon fiber-based mine wastewater treatment system and a groundwater decontamination process. The mine wastewater treatment system comprises a falling water aeration tank, a dosing tank, a primary sedimentation tank and multiple stages of carbon fiber contact oxidation tanks which are connected in series, wherein the falling water aeration tank, the dosing tank, the primary sedimentation tank and the carbon fiber contact oxidation tanks are connected sequentially, the dosing tank is used for adding a pH adjusting agent, the water inlet of the first-stage carbon fiber contact oxidation tank is connected with the water outlet of the primary sedimentation tank, and is provided with a decanter, and the water outlet of the last-stage carbon fiber contact oxidation tank is connected with a river channel or ditches; and the carbon fiber contact oxidation tanks are also provided with sludge discharge pipes and gates, each stage of the carbon fiber contact oxidation tanks is provided with a carbon fiber water purification system, and biofilm and algae fields which are formed by the carbon fiber water purification systems have the functions of retention, adsorption, adhesion, bridging, flocculation, bio-oxidation and bio-enzyme catalytic oxidation of wastewater. Iron manganese oxide which is a product of carbon fiber purification and treatment of wastewater is adopted as a catalyst, the operation cost is low, the decontamination effect is good, and the system is suitable for treatment of large-scale mine wastewater and groundwater sewage.