The invention discloses a 3D printing bionic porous biological
ceramic artificial bone and a preparation method thereof. A porous biological
ceramic artificial bone model is designed through a TPMS and CSG
combined method,
slurry capable of being used for printing is prepared through biological
ceramic powder and a binding agent, macropores and micropores are distributed in the porous biological ceramic
artificial bone prepared through the combination with the 3D filament-free printing process, the
pore diameter of the micropores is smaller than 100 micrometers, the
pore diameter of the macropores is 200-800 micrometers, the total
porosity is 20% to 80%, the communicating rate between the macropores is not lower than 99%, precise design of
porosity, communication and homogeneity in the artificial bone is achieved, and meanwhile good pore communication is ensured. Adopted raw materials have good
biocompatibility, entry passageways of cells and
tissue fluid are provided by the macropores, the micropores can better adsorb
tissue fluid nearby for
cell growth, the
cell growth speed and the new bone generation speed can be increased by combining the micropores with the marcropores, and application of the porous biological ceramic artificial bone in
human body large
bone defect repair clinic treatment is facilitated.