57 results about "Biphenylol" patented technology

A polyethersulfone composition is disclosed which comprises structural units derived from a monomer mixture comprising fluorenylidene bisphenol-A and at least 50 mole percent of 4,4′-biphenol based on total moles of diphenolic monomers, wherein the polyethersulfone has a minimum glass transition temperature of 235° C. and a notched Izod impact value of 1 ft-lb / in. as measured by ASTM D256.

The invention belongs to the technical field of medicines and mainly relates to application of 2-phenylphenol and derivatives thereof to a medicine for treating epilepsia. The structural formula of the 2-phenylphenol derivatives is shown in the specification of the invetion, wherein R1 and R2 can be hydroxide groups, sulfhydryl groups at the same time or one is hydroxide radical and the other is sulfhydryl group; and R1 and R2 can be alkyls of C1-C6, alkenyls of C2-C6, alkyls and aryls of C2-C6 or acyls or alkenyls of C2-C6 and at least one of R1 and R2 is hydroxide group.

Polycarbonates containing low or undetectable levels of Fries rearrangement products and comprising repeat units derived from one or more of resorcinol, hydroquinone, methylhydroquinone, bisphenol A, and 4,4′-biphenol have been prepared by the melt reaction of one or more of the aforementioned dihydroxy aromatic compounds with an ester-substituted diaryl carbonate such as bis-methyl salicyl carbonate. Low, or in many instances undetectable, levels of Fries rearrangement products are found in the product polycarbonates obtained as the combined result of a highly effective catalyst system which suppresses the Fries reaction and the use of lower melt polymerization temperatures relative to temperatures required for the analogous polymerization reactions using diphenyl carbonate.

The invention relates to preparation and application of a zinc ion fluorescence probe based on Schiff base. A zinc ion fluorescence probe compound has the structure shown by a formula I. The preparation method comprises the steps that 2-aminobenzoic acid (methyl anthranilate) and hydrazine hydrate are subjected to heating reflux in ethyl alcohol to obtain a white solid II, cyanophenyl phenol, anhydrous magnesium chloride and paraformaldehyde are subjected to heating reflux in a triethylamine-containing acetonitrile solution to obtain a white solid III, the white solid II and the white solid III are subjected to heating reflux in ethyl alcohol to a yellow solid I. The probe compound has very good selectivity and sensitivity on zinc ions, is low in detection limit and can be applied to determination of the content of zinc ions in a water body.

The invention relates to a novel fluorescence-enhanced probe compound preparation method and a trivalent chromium ion detection method. The chromium ion fluorescence-enhanced probe compound has a structure shown in the formula I. The preparation method comprises mixing 4'-Hydroxy-4-biphenylcarbonitrile, anhydrous magnesium chloride and anhydrous triethylamine in an acetonitrile solvent in a nitrogen protective atmosphere, adding paraformaldehyde into the mixture, carrying out reflux to obtain an intermediate product, carrying out reflux on the intermediate product, 2-chloropyridine hydrochloride, anhydrous potassium carbonate and potassium iodide in an acetonitrile solvent to obtain a second intermediate product, mixing the second intermediate product, phenanthraquinone and ammonium acetate in an ethanol solvent, and carrying out a reaction process in the presence of acetic acid as a catalyst to obtain a desired product probe. The fluorescence-enhanced probe compound has good selectivity and sensitivity to trivalent chromium ions and has a fast response speed. The trivalent chromium ion detection method has a simple sample pretreatment process and is suitable for detection of a trace amount of trivalent chromic ions in water and in the environment.

Liquid crystalline polymer having repeat units derived from 4,4'-biphenol, terephthalic acid, 2,6-naphthalenedicarboxylic acid, and 4-hydroxybenzoic acid in a limited compositional range have melting points of 400° C. or more, and are useful for molded articles and for films, particularly for uses where good high temperature resistance is needed.

The invention relates to an application of 3,3',5,5'-tetraisopropyl-4,4'-diphenol and pharmaceutical salts, ester compounds or solvent compounds thereof in preparation for traditional Chinese medicines for preventing and treating ischemic stroke. The structure of the diphenol structure is specified in the description.

Stable, homogeneous melt solutions are prepared at temperatures of 200° C. or less from solid mixtures comprising at least one diaryl carbonate, at least one high melting dihydroxy aromatic compound (mp>200° C.), a transesterification catalyst, and optionally a lower melting dihydroxy aromatic compound. Thus, a stable, homogeneous melt solution is obtained from a solid mixture comprising 4,4′-biphenol (mp 282-284° C.) at a temperature of about 200° C. using either diphenyl carbonate or bis(methyl salicyl) carbonate as the diaryl carbonate component. It is shown that formation of the stable, homogeneous melt solutions requires the presence of the transesterification catalyst when substantial amounts of the high melting dihydroxy aromatic compound are present in the initial solid mixture. Solid mixtures comprising a variety of high melting bisphenols; 4,4′-biphenol; 3,3,3,3′-tetramethylspirobiindanbisphenol, and 4,4′-sulfonyidiphenol are converted to stable, homogeneous melt solutions at 200° C., a temperature substantially below the melting points of the high melting bisphenols in their pure states.

Stable, homogeneous melt solutions are prepared at temperatures of 200 DEG C or less from solid mixtures comprising at least one diaryl carbonate, at least one high melting dihydroxy aromatic compound (mp>200 DEG C), a transesterification catalyst, and optionally a lower melting dihydroxy aromatic compound. Thus, a stable, homogeneous melt solution is obtained from a solid mixture comprising 4,4'-biphenol(mp 282-284 DEG C) at a temperature of about 200 DEG C using either diphenyl carbonate or bis(methyl salicyl) carbonate as the diaryl carbonate component. It is shown that formation of the stable, homogeneous melt solutions requires the presence of the transesterification catalyst when substantial amounts of the high melting dihydroxy aromatic compound are present in the initial solid mixture. Solid mixtures comprising a variety of high melting bisphenols; 4,4'-biphenol; 3,3,3,3'tetramethylspirobiindanbisphenol, and 4,4'-sulfonydiphenol are converted to stable, homogeneousmelt solutions at 200 DEG C, a temperature substantially below the melting points of the high melting bisphenols in their pure states.

The invention provides an aqueous dispersion for chemical mechanical polishing that can limit scratches of a specific size to a specific number, even with interlayer insulating films with small elastic moduli (silsesquioxane, fluorine-containing SiO2, polyimide-based resins, and the like.). When using the aqueous dispersion for chemical mechanical polishing of an interlayer insulating film with an elastic modulus of no greater than 20 GPa as measured by the nanoindentation method, the number of scratches with a maximum length of 1 μm or greater is an average of no more than 5 per unit area of 0.01 mm2 of the polishing surface. An aqueous dispersion for CMP or an aqueous dispersion for interlayer insulating film CMP according to another aspect of the invention contains a scratch inhibitor agent and an abrasive. The scratch inhibitor may be biphenol, bipyridyl, 2-vinylpyridine, salicylaldoxime, o-phenylenediamine, catechol, 7-hydroxy-5-methyl-1,3,4-triazaindolizine, and the like. The abrasive may consist of inorganic particles, organic particles or organic / inorganic composite particles. The organic / inorganic composite particles may be formed by polycondensation of an alkoxysilane, aluminum alkoxide, titanium alkoxide, and the like in the presence of polymer particles of polystyrene or the like, and bonding of polysiloxane, and the like, on at least the surface of the polymer particles.

The invention discloses synthesis and application of a Pt / BiVO4 composite photocatalyst adopting a laminar structure. The synthesized photocatalyst is a heterogeneous composite photocatalyst which is formed by supporting Pt on laminar BiVO4 surface and has good photocatalytic activity. A Pt / BiVO4 composite adopting the laminar structure is taken as the photocatalyst, a xenon lamp with light emission wavelength lambda larger than 400 nm and the power being 300 W is used for irradiating 2,6-disubstituted phenol at the room temperature, a coupling reaction is performed, and a corresponding biphenol compound is synthesized; or 2,4-disubstituted phenol is irradiated, the coupling reaction is performed, and a corresponding xenol compound in a hydroxy ortho-position is synthesized.

The invention belongs to the technical field of high-molecular polymers, and particularly relates to a liquid crystal polymer film for a flexible copper-clad plate applied to 5G communication and a preparation method of the liquid crystal polymer film. The liquid crystal polymer film provided by the invention comprises a liquid crystal polymer, and the liquid crystal polymer is prepared from the following monomers: p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic acid, biphenol, biphenyl dicarboxylic acid and octafluoro-4,4'-diphenol. The preparation method comprises the steps of prepolymerization, solid phase polycondensation, mixing, melt extrusion, lamination, stretching and winding. According to the invention, binding force between metal copper foil and the liquid crystal polymer film prepared by introducing the novel monomer octafluoro-4,4'-diphenol, the p-hydroxybenzoic acid, the 6-hydroxy-2-naphthoic acid, the biphenol and the biphenyl dicarboxylic acid through copolymerization is substantially improved, peel strength can achieve 1.9 KN / m or more, and the use requirement of the FPC on the high-quality flexible copper-clad plate applied to 5G communication can be met.

A polycarbonate copolymer contains: 0.1 to 50 mol % of a monomer unit represented by the following formula (1); and a monomer unit represented by the following formula (2). In the polycarbonate copolymer, the content of biphenols having a structure represented by the following formula (3) is 90 mass ppm or less.In the formula, R1 and R2 each independently represent a hydrogen atom, an aliphatic hydrocarbon group having 1 to 6 carbon atoms, an aryl group having 6 to 12 carbon atoms or a halogen atom.In the formula: R3 and R4 each independently represent a hydrogen atom, an aliphatic hydrocarbon group having 1 to 6 carbon atoms, an aryl group having 6 to 12 carbon atoms or a halogen atom; and X represents any one of bonding groups represented by —O—, —S—, SO—, —SO2—, —CO— and 9,9-fluorenylidene group.In the formula, R1 and R2 each independently represent a hydrogen atom, an aliphatic hydrocarbon group having 1 to 6 carbon atoms, an aryl group having 6 to 12 carbon atoms or a halogen atom.

The invention relates to a preparation method of novel phosphorus-containing biphenyl novolac epoxy resin and condensate of the novel phosphorus-containing biphenyl novolac epoxy resin. The preparation method of the resin comprises the following steps of: dissolving 4,4'-bipheyl dimethyl dimethyl ether and p-phenylphenol in an organic solvent; heating to reach the temperature of between 60 DEC and 180 DEG C to react for 3 to 8 hours so as to prepare biphenyl novolac resin; performing epoxidation under the action of a base catalyst and keeping a reaction temperature at 50 DEG C to 80 DEG C for 2 to 3 hours to prepare biphenyl novolac epoxy resin; and reacting the biphenyl novolac epoxy resin with a phosphorus-containing activated monomer to prepare the novel phosphorus-containing biphenyl novolac epoxy resin. The phosphorus-containing biphenyl novolac epoxy resin has superior flame retardant property, heat resistance and water resistance; and the preparation method is simple and feasible. The epoxy resin is suitable to be used as a sealing material and an adhesive used in electronic elements and an electric insulating material used in an electronic circuit substrate.

The invention relates to a fluorescence sensing material based on rhodamine B and hydroxy-4-biphenylcarbonitrile, and a preparation method and application thereof, and belongs to the technical fieldsof a fluorescence chemical sensing material and chemical analysis and detection. The preparation method comprises the following steps: dissolving rhodamine diethylenediamine and 3-formyl-4-hydroxy-4-biphenylcarbonitrile into absolute ethanol, adding a proper amount of glacial acetic acid, stirring and refluxing in an oil bath pot, cooling to room temperature after the reaction, reducing pressure and removing the solvent to obtain a crude product, and performing recrystallization in ethanol to obtain the fluorescence sensing material. The fluorescence sensing material prepared by the method hasmultiple responsiveness on four metal ions such as Zn<2+>, Al<3+>, Fe<3+> and Cr<3+>, can realize effective detection on the trace amount of the target metal ions in the environment water sample wellby taking out different fluorescence signals, and has the characteristics of easily available raw materials, simple preparation process, high product stability, high detection sensitivity and the like.

The invention relates to preparation and application of a fluorescent probe capable of rapidly detecting cysteine. The structure of a probe compound is as shown in a formula I in the specification. A preparation method for the probe compound comprises the following steps: introducing an aldehyde group to position 3 of 4-cyanodiphenol in virtue of paraformaldehyde so as to obtain a compound II; subjecting the compound II and pyrrole to nucleophilic addition so as to produce a compound III; reacting the compound III with DDQ and boron trifluoride-diethyl ether successively so as to obtain a compound IV; and subjecting the compound IV and chloroacetyl chloride to a substitution reaction so as to produce the probe compound I. The probe compound can be used for rapid analysis and detection of cysteine and has the characteristics of high sensitivity, low detection limits, etc.

The present invention belongs to the field of chemical medicine, and particularly relates to 3-allyl-[1,1'-biphenyl]-4-phenol, derivatives, preparation methods and uses thereof. A technical problem solved by the present invention is to provide a new class of compounds: 3-allyl-[1,1'-biphenyl]-4-phenol represented by a formula I and derivatives thereof. Experiment results of the present invention show that 3-allyl-[1,1'-biphenyl]-4-phenol represented by the formula I and the derivatives thereof have good effects of anti-tumor, anti-angiogenesis, anti-oxidation and other disease resistance, and provide a new selection for drug preparation.

A polymer composition including a polyetherimide comprising repeating units of formula (1) and formula (2) [Formula should be inserted here] wherein the repeating units of formula (1) are present in an amount of at least 10 mole %, preferably 20 to 100 mole %, Z is independently at each occurrence derived from a biphenol; Z′ is independently at each occurrence a group of formulas (3) to (13) as defined herein, preferably bisphenol A, 1,2-dihydroxybenzene, 1,1-bis(4-hydroxyphenyl)-1-phenyl-ethane, isophorone bisphenol (1,1-bis(4-hydroxyphenyl)-3,3,5-trimethylcyclohexane), spirobiindane bisphenol, dimethylindanone bisphenol, 3,3′-dimethylbisphenol cyclohexane, or fluorenone bisphenol; and R is independently at each occurrence as a C6-20 aromatic hydrocarbon group or a halogenated derivative thereof, a straight or branched chain C2-20 alkylene group or a halogenated derivative thereof, a C3-8 cycloalkylene group or halogenated derivative thereof; wherein the polyetherimide has a Tg of greater than 200° C.

Compositions and methods for a semicrystalline poly(aryl ether ketone) copolymers incorporating 2-benzimidazolinone and 4,4′-biphenol as comonomer units with 4,4′-dihalobenzophenone, and compositions and methods for semicrystalline poly(aryl ether ketone) copolymers incorporating 2-benzimidazolinone and 4,4′-biphenol as comonomer units with 1,4-bis(4-dihalobenzoyl)benzene are described herein. The Copolymers have advantageous properties, particularly in terms of high glass transition temperatures (Tg), high melting temperatures (Tm), crystallinity and chemical resistance. The copolymers are suitable for manufacturing high temperature and chemical resistance molded systems and other articles of manufacture via injection molding, extrusion, compression molding, coating, and additive manufacturing.

The present invention relates to an antimicrobial composition. More particularly the present invention relates to an antimicrobial composition for malodor and oral biofilm inhibitions benefits. Accordingly, the present invention provides an antimicrobial composition comprising: a. 0.1 to 10% by weight of tetrahydroxypropyl ethylenediamine (THPE) and, b. 0.001 to 10% by weight of at least one compound selected from a biphenol.

The invention discloses a compound to induce structure to generate crosslinking action of nucleic acid, which comprises the following steps: transmitting phenolic hydroxyl group in the 2, 6-dimethyl phenol, diphenol or hydroquinone into benzyl bromine under alkaline condition; substituting benzyl bromine group into selenium benzene group acted by sodium borohydride and diphenyl sulphone diselenide; stripping protection to obtain compound 1, compound 2 or compound 3.

The present invention relates to a compound of formula I or a pharmaceutically acceptable salt thereof. In formula (I), R 1 and R 2 Each independently is H or alkyl; Y is alkyl, CONR 3 R 4 、COOR 5 , SO 2 NR 16 R 17 , NHSO 2 R 18 or CN; X is aryl or heteroaryl, each of which may optionally be substituted by one or more substituents selected from (CH 2 ) m Z, where Z is halogen, OH, CN, alkyl, alkoxy, NO 2 、CF 3 、CONR 6 R 7 , CN, NR 8 R 9 、COOR 10 or NHCOR 11 , m is 0 to 3; R 3 to R 11 Each is independently H, alkyl or aryl, wherein the alkyl and aryl are optionally substituted by one or more substituents selected from halogen, OH, CN, alkyl, alkoxy , NO 2 、CF 3 、CONR 12 R 13 , CN, NH 2 、COOR 14 , NHCOR 15 and CN; R 12 to R 18 Each independently is H or alkyl, more preferably H or Me; n is 1 to 6; wherein the compound is not 3',5'-dimethyl-4-(1,1-dimethylheptyl)- 1,1'-biphenyl-2-phenol. Another aspect of the invention relates to the use of such compounds for the manufacture of a medicament for the treatment of muscular disorders, gastrointestinal disorders or for the control of spasticity or tremor.

The invention discloses an ionic phosphoramidite ligand, a preparation method and application of the ionic phosphoramidite ligand in hydroformylation reaction. A general formula of the ligand is shownin the specification. The preparation method comprises the following steps: dissolving phosphorus trichloride and imidazole in a solvent, conducting stirring for reaction, conducting filtering, dissolving substituted biphenol in a solvent, dropwisely adding the formed solution into the filtrate for reaction, and purifying the obtained product to obtain phosphoramidite; and reacting phosphoramidite with a quaternization reagent in a solvent to obtain a product, and purifying the product to obtain the ionic phosphoramidite. Through the method provided by the invention, a series of neutral phosphoramidite ligands can be conveniently synthesized, and a series of ionic phosphoramidite ligands with different physicochemical properties can be efficiently synthesized through a quaternization method.

The invention relates to the field of plastic, in particular to corrosion resistant and heat resistant modified plastic applied to preparation of special pipelines, with excellent chemical reagent tolerance and high temperature tolerance, and a preparation technology thereof. The plastic comprises the following preparation materials in parts by weight: 400 to 600 parts of epoxy-modified organic silicon resin, 720 to 1150 parts of emery powder, 280 to 350 parts of titanium dioxide, 55 to 85 parts of glass powder, 360 to 525 parts of modified epoxy resin, 290 to 370 parts of biphenyl novolac, 180 to 310 parts of benzoxazine, 110 to 135 parts of a modifier, 215 to 315 parts of industrial pure aluminum powder, 95 to 130 parts of industrial pure magnesium powder, 15 to 25 parts of high purity aluminum powder, 40 to 75 parts of aluminum copper alloy powder, 15 to 32 parts of aluminum manganese alloy powder, and 11 to 19 parts of aluminum zirconium alloy powder.

The invention provides a purification method and application of a 2, 2 '-biphenoxy phosphorus-chlorine compound, and the purification method comprises the following steps: after the reaction of a 2, 2'-biphenol compound and phosphorus trichloride is finished, adding a composition of organic amine and a mixed solvent to carry out program temperature control distillation purification to obtain the 2, 2 '-biphenoxy phosphorus-chlorine compound; the purification method can effectively reduce the concentration of residual hydrogen chloride, phosphorus trichloride and incompletely reacted aryloxy phosphorus dichloride in reactants, improves the yield and purity of the 2, 2 '-biphenoxy phosphorus-chlorine compound, can effectively improve the yield and purity of bisphosphite when being used in the synthesis of bisphosphite, can effectively reduce content of phosphorus impurities, acid and chloride ions in the bisphosphite is effectively reduced, and meets various requirements of industrial application control indexes.

The invention belongs to the technical field of diphenol preparation, and particularly relates to a preparation method and application of p-phenylacetophenone. The invention provides a preparation method of p-phenylacetophenone, wherein the method comprises the following step: in an organic solvent, dehydrating biphenyl and acetic acid under the action of an H-type molecular sieve catalyst under the conditions of high temperature and high pressure to generate p-phenylacetophenone. According to the invention, an H-type molecular sieve catalyst is introduced into a p-phenylacetophenone generation process for the first time, the purpose of producing p-phenylacetophenone by using cheaper acetic acid as a raw material is achieved by utilizing the structural characteristics of the H-type molecular sieve catalyst, and the production cost of p-phenylacetophenone is greatly reduced; the production process has few reaction steps, and the product purity and yield are obviously improved; and the process solves the problem that a large amount of aluminum trichloride wastewater is generated in the existing p-phenylacetophenone generation process.

The invention discloses a biphenol-based organic solvent composite nanofiltration membrane and a preparation method thereof, and belongs to the technical field of separation membranes. The preparation method comprises the following steps: by taking a polyacrylonitrile or polyimide ultrafiltration membrane as a base membrane, removing a surface pore-retaining agent, firstly soaking in an aqueous solution containing a 2, 2 '-diphenol compound, then soaking in an organic solution containing multi-acyl chloride to carry out interfacial polymerization reaction, and finally, carrying out thermal crosslinking drying to obtain the composite nanofiltration membrane. The composite nanofiltration membrane disclosed by the invention has relatively high stability in various polar organic solvents, has high selectivity and permeability to organic molecules, and has relatively high economic value in separation of an organic solvent system in industry.

The present disclosure relates to a liquid crystal polyester composition that can be injection molded into an ultra-thin film and has improved fluidity, and a manufacturing method thereof. The polyester resin composition for ultra-thin injection molding includes 60 to 85% by weight of a liquid crystal polyester resin and 15 to 40% by weight of an inorganic filler having an average cross-sectional aspect ratio of 2 to 6, based on the total weight of the composition, wherein the liquid crystal polyester resin includes 0.1 to 10 mol % of hydroxybenzoic acid (HBA), 40 to 60 mol % of hydroxynaphthoic acid, 20 to 30 mol % of biphenol, and 20 to 30 mol % of terephthalic acid. The liquid crystal polyester resin composition for ultra-thin injection molding according to the present disclosure not only has excellent mechanical strength and heat resistance, but also can exhibit very excellent fluidity in a high-speed injection process.

A multifunctional naphthol-based epoxy resin composition which is a reaction product of a) a naphthol which is a reaction product of i) from 1 to 99 weight percent 1-naphthol and ii) from 1 to 99 weight percent 2-naphthol; and b) an epihalohydrin, is disclosed. Also disclosed is a curable composition comprising: a) an epoxy component comprising the multifunctional naphthol-based epoxy resin composition; and b) a hardener component comprising i) a phenolic resin component selected from the group consisting of phenol novolac resins, triphenolalkane phenolic resins, aralkyl phenolic resins, biphenyl phenolic resin, biphenyl aralkyl phenolic resins, substituted naphthalene phenolic resins unsubstituted naphthalene phenolic resins, and combinations thereof; and ii) a phosphorus-containing composition which is the reaction product of an etherified resole with 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO). The curable composition can be used to prepare prepregs, electrical laminates, printed circuit boards, and printed wiring boards.