11 results about "Butyric acid ester" patented technology

The application provides a preparation method of 4-(hydroxymethyl phosphinyl)-2-oxobutanoic acid, comprising the following steps: a) adding 4-halogen-2-oxobutanoate into dialkyl methyl phosphite dropwise and controlling the temperature to be-30-40 DEG C, and performing a reaction under vacuum to obtain an intermediate liquid; b) mixing the intermediate liquid obtained in the step a) with an acid, performing a hydrolysis reaction, and then performing a purification treatment to obtain 4-(hydroxymethyl phosphinyl)-2-oxobutanoic acid. Compared with the prior art, the preparation method provided by the application uses dialkyl methyl phosphite and 4-halogen-2-oxobutanoate as raw materials, utilizes the SN2 intramolecular rearrangement mechanism, can realize high-efficiency construction of a P-C bond, and the one-step yield of the Arbuzov reaction can be more than 95%, and the final target product 4-(hydroxymethyl phosphinyl)-2-oxobutanoic acid can be obtained through subsequent acidic hydrolysis of the skeleton structure, and the overall yield can be close to 90%; compared with other methods, the preparation method provided by the application is simple in steps, has few reaction by-products, and has a great improvement in yield.

A foodstuff can include a free acid β-hydroxybutyrate, and a base. The β-hydroxybutyrate, and base, are present at a less than 1:1 molar equivalence. Ketone Ester may also be incorporated as a component of the foodstuff.

The application discloses cupriavidus capable of producing polyhydroxyalkanoate by using various carbon sources such as ethanol and application thereof. Cupriavidus The strain sp.ZWJ01 has a preservation number of CGMCC No.37462 in the China General Microbiological Culture Collection Center. The strain can grow and accumulate poly-3-hydroxybutyric acid ester by using various substances such as ethanol, volatile fatty acid and sugar as carbon sources; can grow by using mixed carbon sources of ethanol+propionic acid or ethanol+valeric acid and accumulate poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid ester) in cells; and can grow by using mixed carbon sources of ethanol+gamma-butyrolactone or ethanol+1,4-butanediol and accumulate poly(3-hydroxybutyric acid-co-4-hydroxybutyric acid) in cells, and has a good application prospect.

The present disclosure relates to biomedical and nutritional uses of highly purified (R)-3′-hydroxybutyl (R)-3′-hydroxybutyrate and (R)-3-hydroxybutyrate. In some embodiments, these compounds are employed for enhancing bodily functions and treating various disease states, including cognitive function, muscle power output, inflammation reduction, metabolic disorders, and mitochondrial function. The methods involve combining these ketone esters with natural supplements or medications to improve health outcomes. The disclosure further includes processes for manufacturing and purifying these compounds to ensure high specificity and efficacy in therapeutic applications, providing a comprehensive and enhanced strategy for advancing health and treating diseases.

A foodstuff can include a free acid β-hydroxybutyrate, and a base. The β-hydroxybutyrate, and base, are present at a less than 1:1 molar equivalence. Ketone Ester may also be incorporated as a component of the foodstuff.

The present invention discloses the prodrugs of hexahydro-β-acid compounds, feed composition and use thereof, and a prodrug of hexahydro-β-acid compound of formula (I), or solvates thereof, or feed-acceptable salts thereof, wherein R1 is selected from a substituted or unsubstituted C1-C2 alkyl, and each of R2 and R3 is independently selected from H and a linear or branched C2-C4 carbonyl, wherein the C2-C4 carbonyl is substituted or unsubstituted. Disclosed herein is that the prodrug of a hexahydro-β-acid compound from esterification by aliphatic acid exhibits excellent stability at high temperature to overcome the problem resulting from the degradation of hexahydro-β-acid compound in a high-temperature pelleting process. Furthermore, disclosed herein is that, both propionate and butyrate, the prodrugs of a hexahydro-β-acid compound from esterification by aliphatic acid, and feed-acceptable salt thereof and solvate thereof, are stable in high-temperature feed processing and achieve effects substantially equal to the hexahydro-β-acid compound in farm breeding.

The present invention relates to a novel additive, and to a non-aqueous liquid electrolyte and a gel-type or solid polymer electrolyte containing same. More specifically, the present invention relates to a novel additive and a non-aqueous liquid electrolyte and a gel-type or solid polymer electrolyte containing same, the novel additive comprising a siloxane compound that includes an amine group substituted with an electron-withdrawing functional group, or an isocyanate group, a boronate pinacol ester group, a butylate group, a hexanoate group, a heptanoate group, a cyclohexanopropionate group, and a diethyl phosphate group, and improving electrochemical stability, thermal stability, flame retardancy, and cycle life of an alkali metal battery to which the additive is added.

The application provides a polyhydroxyaliphatic ester composition and a preparation method thereof, a biodegradable plastic product and application thereof. The biodegradable plastic product is prepared by the following method, which comprises the following steps: mixing at least two kinds of 3-hydroxybutyrate and 4-hydroxybutyrate copolymers, melting, extruding and granulating to obtain polyhydroxyaliphatic ester particles; the at least two kinds of 3-hydroxybutyrate and 4-hydroxybutyrate copolymers at least include a block copolymer with a mass percentage of 4-hydroxybutyrate structural unit of 0-20%, and at least include a random copolymer of 3-hydroxybutyrate and 4-hydroxybutyrate; the polyhydroxyaliphatic ester particles are formed to obtain a preformed part; and the preformed part is post-processed to obtain the biodegradable plastic product. The biodegradable plastic product has excellent toughness, low migration, good processing and forming performance and low odor.

Use of a ketone body and a ketone body ester for preserving glycogen and / or protein, thereby reducing muscle breakdown and improving endurance during exercise and promoting muscle recovery following exercise. Also for retarding muscle wasting in aging and disease. (R)-3-hydroxybutyl (R)-3-hydroxybutyrate for use in reducing muscle glycogen and protein breakdown during exercise or decreasing muscle wasting in aging and disease. Certain esters of hydroxybutyrate monomers, particularly a monoester of D-β-hydroxybutyrate with R-1,3-butanediol or with glycerol to reduce muscle breakdown and aid muscle recovery after exercise or retard muscle wasting. Compositions containing the ketone bodies or ketone body esters are also described.

A beverage can include D ethyl 3-hydroxybutyrate, D 1,3-butanediol, D Beta hydroxybutyrate salts, D Beta hydroxybutyrate / D 1,3-butanediol monoester, D ethyl hydroxybutyrate, hydroxybutyrate, and / or D hydroxybutyric acid of at least 0.5 percent by volume. The percentage of D ethyl 3-hydroxybutyrate, D 1,3-butanediol, D Beta hydroxybutyrate salts, D Beta hydroxybutyrate / D 1,3-butanediol monoester, D ethyl hydroxybutyrate, hydroxybutyrate, and D hydroxybutyric acid can be between 5 and 19 percent, or can be higher than 19 percent. The beverage can be improved by the incorporation of flavor from hops and / or from other ingredients.