The invention discloses an antibacterial dressing based on
gallic acid-
copper coated gamma-
polyglutamic acid and a preparation method and application thereof, and belongs to the technical field of biomedicines.The preparation method comprises the steps that
gallic acid and
copper chloride dihydrate are dissolved in pure water according to the
mass ratio of 3: 1, and stirring is conducted to form a solution I; stirring and reacting the solution I at 40 DEG C for 24 hours, centrifuging, collecting precipitate, washing with pure water, and freeze-
drying to obtain
gallic acid-
copper nanoparticles; the gallic acid-copper nanoparticles and gamma-
polyglutamic acid powder are mixed and dissolved in pure water according to the
mass ratio of 3: 20, and after
freeze drying, gallic acid-copper coated gamma-
polyglutamic acid hydrogel
powder is obtained. The gallic acid-copper coated gamma-polyglutamic acid hydrogel
powder disclosed by the invention can absorb
exudate near a wound and is subjected to in-situ gelation to form a hydration layer, so that damage to newborn tissues caused by frequent dressing replacement is avoided; it is verified that the healing promoting effect of the hydrogel can be remarkably enhanced through
blue light adjuvant therapy, and the healing speed of infected wounds is remarkably increased.