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1 results about "Nitrobenzoates" patented technology

Benzoic acid or benzoic acid esters substituted with one or more nitro groups.

Taraxasterol nitrobenzoate derivatives and their anti-tumor applications

This invention relates to a taraxasterol nitrobenzoate derivative in the field of medicinal chemistry, with the following structural formula: Compound B is obtained by reacting taraxasterol 1 with 4-nitrophthalic anhydride in a suitable alkaline catalyst and organic solvent. This synthetic route offers high yield and is easy to implement. Activity tests demonstrate that the taraxasterol nitrobenzoate derivative shown as B, designed and synthesized in this invention, is a suitable antitumor drug candidate, particularly as a candidate drug for lung cancer.
Owner:ZUNYI MEDICAL UNIVERSITY