68 results about "Polypropyleneimine" patented technology

A method for reducing odor is provided. The method comprises forming a coordination complex between a transition metal and a polydentate compound, and contacting the coordinated complex with an odorous compound. The transition metal provides one or more active sites for capturing the odorous compound. In some embodiments, the polydentate compound may be a polyalkylimine, such as polyethyleneimine, polypropyleneimine, or a dendrimer thereof.

A water-based drilling fluid and method of using same are presented in this disclosure, which fluid is used in drilling wells through a formation containing a shale that swells in the presence of water. The drilling fluid comprises an aqueous based continuous phase; a weighting material; and a shale hydration inhibition agent (SHIA) selected from the group consisting of propylamine derivatives, hydrogenated poly(propyleneimine) dendrimers (HPPID), and polyamine twin dendrimers (PTD). In some embodiments, the SHIA of this disclosure is not hydrolyzed at a temperature in the range of from about 100° F. to about 500° F. The drilling fluid may further comprise a fluid loss control agent, an encapsulating agent, other additives, and combinations thereof. A method of reducing shale swelling during wellbore drilling is also described. The method comprises circulating in the subterranean well a water-based drilling fluid comprising an aqueous based continuous phase, a weighting material, and a SHIA.

The invention provides a dendrimer gene transfection carrier modified by a fluorine-containing aromatic ring compound as shown in a formula (I) or a formula (I'). The dendrimer gene transfection carrier comprises a dendrimer skeleton and a fluorine-containing aromatic ring compound functional group which is covalently linked to the surface of the dendrimer; and the dendrimer comprises a polyamide-amine dendrimer and a polypropyleneimine dendrimer. The invention also provides a preparation method of the gene transfection carrier and an application of a composition of the gene transfection carrier as a nucleic acid molecule transporting carrier. The preparation method is characterized in that the dendrimer is modified by a brand-new modification method and a functional group, the reaction is simple and efficient and the yield is high, an efficient transfection effect can be achieved in a cell transfection process, the material is simple to produce and low in cost, the toxicity caused by the transfection process on cells is low, and gene molecules can be transported to cells efficiently and safely; and the gene transfection carrier has the advantages of high efficiency, low toxicity, low price, simple synthesis and the like.

The invention provides a bromine-substituted aromatic compound modified cationic polymer material represented by formula (1). The bromine-substituted aromatic compound modified cationic polymer material comprises a cationic polymer skeleton and a bromine-substituted aromatic compound function group covalently connected to the surface of the cationic polymer; the cationic polymer skeleton comprises polyamidoamine dendrimer, polypropyleneimine dendrimer, linear polyethyleneimine cationic polymer, a branched polyethyleneimine cationic polymer and a derivative thereof; and the polymer material is can be used as a carrier for medicines, nucleic acids and proteins. The bromine-substituted aromatic compound modified polymer has the advantages of low synthesis cost, small cytotoxicity and high transfection efficiency, and is a carrier material with good application prospect.

The present invention is concerned with modified poly-(propylene imine) dendrimers, comprising cationic internal ammonium groups and external non-toxic endgroups, pharmaceutical compositions comprising said dendrimers, methods for the production of said dendrimers and their use as transfections agents for anionic bioactive therapeutic factors, for use in gene therapy, in particular for the treatment of cancer. The modified poly-(propylene imine) dendrimer of generation 1, 2, 3, 4 or 5, also comprising incomplete dendrimers and mixtures thereof, comprising external end groups and internal amine functions are characterized in that:

• (a) substantially all external endgroups are groups of formula (I)

The invention discloses a method of preparing a primary amine compound by reducing a cyano group. The method is characterized in that the primary amine compound is integral generation PPI (Polypropyleneimine) dendrimer. The method comprises a step of reducing half generation PPI dendrimer in alkaline solution with sodium borohydride under normal pressure by taking Raney Ni as a catalyst under an alkaline condition, wherein the reaction is performed in the solution; the mass ratio of the Raney Ni to the half generation PPI is 1:1-7.5:1; and the molar ratio of the sodium borohydride to the cyano group in the half generation PPI is 1.5:1-4:1. The preparation method can be performed under normal pressure; and a product has the advantages of high yield and high primary amine content.

The invention provides an application of a phenylboronic acid-containing modified high polymer material in intracellular delivery of proteins and polypeptides, the phenylboronic acid-containing modified high polymer material is composed of a cationic polymer and a phenylboronic acid-containing functional group, and the phenylboronic acid-containing functional group is covalently connected to the cationic polymer; the cationic polymer comprises a polyamide-amine dendrimer, polypropyleneimine, polylysine and the like; the phenylboronic acid-containing modified high polymer material can be used as an intracellular delivery carrier for proteins and polypeptides, i.e., protein and polypeptide molecules are delivered from extracellular to intracellular carriers. The method for using the phenylboronic acid-modified polymer material as a protein and polypeptide intracellular delivery carrier can achieve high efficiency, is effective to proteins with different molecular weights and isoelectricpoints, can maintain the biological activity of the proteins, has low toxicity to cells, and has good biocompatibility.

Provided is a reagent for assaying a thrombin-antithrombin complex (TAT) in a blood sample from a subject by latex agglutination assay. The reagent includes a polycation. As a result, TAT complexes can be precisely assayed while circumventing the effect of heparin. The polycation is, for example, hexadimethrine bromide, chitosans, modified dextran, aminodextran, hydroxymethyl cellulose trimethylamine, lysozyme, spermine, spermidine, polylysine, polyarginine, polyornithine, protamine sulfate, hydroxyethyl cellulose trimethylamine, heparin-binding protein, polyallylamine, polyallylamine hydrochloride, poly(diallyl dialkyl amine), polyamideamine, polyamine, polyvinylbenzyltrimethylammonium chloride, polydiallyldimethylammonium chloride, polyethyleneimine, polypropyleneimine, polypropylethyleneimine, polyimidazoline, polyvinylamine, polyvinyl pyridine, poly(acrylamide/methacryloxypropyltrimethylammonium bromide), poly(diaryldimethylammonium chloride/N-isopropylacrylamide), poly(dimethylaminoethyl acrylate/acrylamide), poly(dimethylaminoethyl methacrylate), polydimethylaminoepichlorohydrin, polyethyleneiminoepichlorohydrin, polymethacryloxyethyl-trimethylammonium bromide, hydroxypropylmethacryloyloxyethyl dimethyl ammonium chloride, poly(methyldiethylaminoethylmethacrylate/acrylamide), poly(methyl/guanidine), polymethylvinylpyridinium bromide, poly(vinylpyrrolidone-dimethylaminoethyl methacrylate), or polyvinylmethylpyridinium bromide.

The invention discloses a method for preparing an anti-flaming silk. The method comprises the following steps: preparing dioscorea cirhosa extract; utilizing a dipping adsorption method to absorb thecondensed tannin in the dioscorea cirhosa extract to a silk fabric, thereby acquiring a dioscorea cirhosa extract modified silk fabric; utilizing the dipping adsorption method to absorb a polypropylene imine dendrimer to the dioscorea cirhosa extract modified silk fabric under a weak alkaline condition, thereby acquiring the anti-flaming silk. According to the invention, the cross-linking reactionof the condensed tannin in the dioscorea cirhosa extract and the polypropylene imine dendrimer on the silk fabric under the weak alkaline condition is utilized to effectively promote the flame resistance of the silk fabric. The silk fabric finished according to the method provided by the invention has a durable anti-flaming function.

The invention discloses a surface amine functionalized rare earth doped barium fluochloride nanometer fluorescence labeling material and a preparation method thereof, and relates to a surface functionalized water soluble nanometer fluorescence labeling material preparation. The formula of the barium fluochloride nanometer fluorescence labeling material prepared by the method of the present invention is XLn<3+>-(1-x)BaFCl (Ln=Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb; X=0-60 mol% ). According to the preparation method, polypropylenimine is adopted as a surfactant, and a one-step reaction is performed to prepare the surface amine functionalized water soluble rare earth doped barium fluochloride nanometer fluorescence labeling material, wherein the results of transmission electron microscope, infrared absorption spectrum, gravitational thermal analysis and other test methods show that the polypropylenimine is effectively coated on the surfaces of the nanoparticles. The prepared nanometer powder has good solubility; with the amino groups on the surface, the basis is established for the further combination of the biological molecules; with the rare earth ion doping, the material can achieve the purposes of strong luminous intensity, and rare earth ion fluorescence emission with long fluorescence lifetime.

The invention relates to a preparation method of caramel inflaming retarding liquid and a method for inflaming retarding finishing of a wool fiber product. The preparation method of the caramel inflaming retarding liquid comprises the steps that after the pH value of a micromolecule sugar solution is adjusted through a poly propylene imine polymer, caramelization is carried out under the alkalinecondition, the caramel inflaming retarding liquid is prepared, and micromolecule sugar is monosaccharide or disaccharide. The method for inflaming retarding finishing of the wool fiber product comprises the steps that after the pH value of the caramel inflaming retarding liquid is adjusted to be acid, the caramel inflaming retarding liquid is used as inflaming retarding finishing liquid, the woolfiber product is finished through a dipping-roasting method, and the roasting temperature is not lower than the temperature that the poly propylene imine polymer and the wool fiber product generate achemical reaction. In the method, the raw materials monosaccharide and disaccharide are natural materials, and the prepared caramel inflaming retarding liquid is an environment-friendly inflaming retarding system. In the method, the raw materials are easy to obtain, the preparation process is simple, the prepared inflaming retarding wool fiber product has good inflaming retarding performance and washing resistance, and important inflaming retarding value is achieved.

The invention provides a method for separating RBCs (Red Blood Cell) from whole blood, wherein the core of the method is an RBC separating agent which comprises the following components: carboxyl polystyrene microspheres, active group dendritic polymers and anti-human RBC antibodies; wherein the active group dendritic polymer is polylysine, dendritic polyamidoamine or polypropylenimine n-dotriacontane amine. The RBC separating agent is realized by utilizing a polylysine modified polystyrene microsphere-antihuman RBC antibody compound, the RBC separating agent is added into a sample diluent ofan immunochromatography kit or a specific blood processing tube thereof in advance, the RBC separating agent can be quickly combined with RBCs in a test sample in the testing process to quickly form ahuge reticular structure, and quick sedimentation is realized under the action of gravity, so that a supernatant required by reaction is obtained.

The invention discloses a method for quickly detecting tert-butylhydroquinone in food, which comprises the following steps: reducing chloroauric acid by using copper iodine doped carbon dots as a reducing agent and polypropyleneimine as a protective agent to obtain gold nanoparticles, forming a mixed nano-enzyme system by using excessive Cu-I/CDs and AuNPs, and establishing a novel high-sensitivity and high-selectivity TBHQ detection method by using tert-butylhydroquinone as a substrate and oxidized TBHQ as a red oxidized quinones substance based on the linear relationship between the TBHQ concentration and the red oxidized TBHQ, wherein the detection limit is 0.5 mg/kg; the method is applied to the detection and analysis of TBHQ in food, and the result conforms to the determination methodof nine antioxidants in food of the national food safety standard GB5009.32-2016; the method can only selectively oxidize TBHQ, other antioxidants do not have the reaction, and the method has the characteristics of high sensitivity, strong specificity, simplicity and rapidness in operation and the like.

The invention relates to the technical field of molecular imprinting, and discloses a preparation method of magnetic attapulgite surface imprinted polymer modified by dendritic macromolecules. The preparation method comprises the following steps: 1) preparing magnetic attapulgite nanoparticles; 2) alkylating that magnetic attapulgite nanoparticles; 3) grafting: adding alkylate magnetic attapulgitenanoparticles into polypropylene imine solution, stirring and reacting to obtain polypropylene imine magnetic attapulgite nanoparticles; 4) preparing imprinted polymer: mixing template molecules, polypropylene imine magnetic attapulgite nanoparticles and acetonitrile, standing, separating solid particles, adding solid particles, functional monomer, crosslinking agent and initiator into acetonitrile, stirring, reacting, magnetically separating and drying, washing template molecules through Soxhlet extraction, separating and drying. The magnetic attapulgite surface imprinted polymer prepared bythe invention has the characteristics of large adsorption capacity and no easy desorption.

The invention relates to the technical field of imprinted polymers, and discloses a preparation method of a polypropylene imine modified magnetic nanocrystalline cellulose molecular imprinted polymer.The preparation method comprises the following steps: 1) preparing magnetic nanocrystalline cellulose; 2) carrying out alkylation treatment; 3) adding alkylated magnetic nanocrystalline cellulose into a polypropylene imine solution to obtain polypropylene imine grafted nanocrystalline cellulose; and 4) adding the polypropylene imine grafted nanocrystalline cellulose, paclitaxel and a methacrylicacid monomer into an acetone solvent to carry out stirring and dissolving, adding ethylene glycol dimethacrylate and azobisisobutyronitrile, and carrying out heating for reacting to obtain the polypropylene imine modified magnetic nanocrystalline cellulose molecular imprinted polymer. According to the invention, nanocrystalline cellulose is use as a carrier, and the functional monomer methacrylicacid is crosslinked on the surface of a carrier to form spherical imprinted polymer microspheres. The spherical imprinted polymer microspheres have a high specific surface area, binding sites with template molecules are increased, and thus the utilization rate of imprinted polymer molecules is increased.

The invention discloses a geogrid resistant to heat and humidity, which is composed of the following raw materials in parts by weight: zinc dihydrogen phosphate 4-5, phosphite 2-3, dimethyl diallyl chloride Ammonium 0.6‑1, polypropylene imine 10‑17, tert-butyl acrylate 6‑8, lithium aluminum hydride 0.1‑0.3, 4‑dimethylaminopyridine 0.3‑1, antioxidant 10100.4‑1, multi-walled carbon nanotubes 10-15, antioxidant 1680.6-1, high-density polyethylene 140-160, chlorinated paraffin 4-6, titanium dioxide 10-12, butyltin trioctoate 0.4-1, amino trimethylene phosphonic acid 0.1-0.2, di Phenylsilanediol 2‑3, calcium hexafluoroacetylacetonate 0.4‑1. The geogrid of the invention has good resistance to heat and humidity, good impermeability, and is not easy to corrode.

The invention discloses a hybrid dendritic polymer supported metal catalyst and a preparation method and application thereof. The catalyst is characterized in that polyacrylic imide modified by a 15-membered triolefinic macrocycle is taken as a carrier; one or two of Ru<3+>, Rh<3+>, Pd<2+>, Pt<2+> and Pt<4+> are taken as compounds of metal ions. In the preparation method, Gn1-M is taken as a carrier, and a way of complexing the carrier with the metal ions is adopted to prepare the metal catalyst. The metal catalyst is applied to catalytic hydrogenation on an unsaturated dialkene polymer. The catalyst prepared by the method has superior catalytic activity and selectivity, and efficient recovery of noble metal catalysts can be realized.