26 results about "Propanoyl chloride" patented technology

The invention relates to the field of pipes, and discloses a high-strength CPVC pipe and a preparation method thereof.The pipe comprises CPVC resin, modified multi-walled carbon nanotubes, modified nano silicon dioxide and auxiliaries; the modified multi-walled carbon nanotubes are prepared by grafting phosphorus-containing cardanol derivative based benzoxazine and oxidized multi-walled carbon nanotubes; phosphorus-containing cardanol derivative benzoxazine reacts with 1, 5-naphthylenediamine to prepare an aldehyde cardanol intermediate, the aldehyde cardanol intermediate is prepared by reacting paraformaldehyde with hydrogenated cardanol, the obtained cardanol derivative and DOPO are subjected to addition, and then the obtained phosphorus-containing cardanol derivative reacts with paraformaldehyde and 3-aminopropyltriethoxysilane to prepare the flame retardant. The modified nano silicon dioxide is prepared by introducing polyethylene glycol into the surface of isocyanated nano silicon dioxide and grafting with 3, 5-bis (tert-butyl)-4-hydroxybenzene propionyl chloride, and the pipe prepared by the invention is high in tensile strength and impact strength and has good long-acting oxidation resistance, high temperature resistance and flame retardance.

The application discloses a triazolinone compound, and a preparation method thereof. The structural general formula (I) of the triazolinone compound is as follows: the preparation method is to perform esterification or amidation reaction on a compound containing a hydroxyl group or an amino group as raw material in a solvent and 2-chloro-3-(2-chloro-5-(4-difluoromethyl-3-methyl-5-oxo-1,2,4-triazol-1-yl)-4-fluorophenyl) propionyl chloride prepared through acyl chloride reaction, so as to obtain a triazolinone structure-containing herbicidal compound. The preparation method is simple, the reaction process is short, and the triazolinone structure-containing herbicidal compound has the advantages of novel structure, high herbicidal activity and the like.

Disclosed are a pyrethroid compound containing a cyano group and a double bond, a synthesis method therefor and an application thereof. In the synthesis method, t-butyl 3-formyl-2,2-dimethyl-cyclopropanoate and cyanomethyl phosphonate are used as raw materials, undergo Witting-Horner reaction, undergo column chromatography to obtain t-butyl (Z)-3-(2-cyanovinyl)-2,2-dimethyl-cyclopropanoate ester, undergo deprotection to obtain (Z)-3-(2-cyanovinyl)-2,2-dimethyl-cyclopropanoic acid, undergo acyl chlorination reaction to produce (Z)-3-(2-cyanovinyl)-2,2-dimethyl-cyclopropanoyl chloride, and are esterified with corresponding alcohol to obtain the pyrethroid compound. The compound can be used as an insecticide against pests such as mosquitoes, flies, German cockroaches and the like.

The invention belongs to the technical field of chemical synthesis, and particularly relates to a synthetic method of butylphenylmorpholine, which comprises the following steps of: reacting tert-butylbenzene with propionyl chloride to obtain tert-butylpropiophenone, reacting the product with cis-2, 6-dimethylmorpholine and paraformaldehyde to obtain 4-tert-butyl-1-(2-methyl-1-oxy-3-(cis-2, 6-dimethylmorpholine-4-) propyl) benzene, and reacting the 4-tert-butyl-1-(2-methyl-1-oxy-3-(cis-2, 6-dimethylmorpholine-4-) propyl) benzene with the product to obtain the butylphenylmorpholine. And reducing hydrogen under the action of a catalyst to obtain the butylphenylmorpholine. By optimizing a raw material route and process conditions, the defects of high cost, low purity and dependence on an acid-binding agent in the prior art are overcome, special equipment is not needed, and the method is suitable for industrial continuous production.

This invention belongs to the field of pharmaceutical synthesis, specifically relating to a method for preparing etorizine hydrochloride and its intermediates. Specifically, it involves reacting propionyl chloride and ethylbenzene at -80 to -50°C to obtain p-ethylphenylacetone, which is then reacted with piperidine and paraformaldehyde to form a salt, yielding etorizine hydrochloride. The method for preparing p-ethylphenylacetone provided by this invention can obtain a product with a low content of compound II. Using this as a raw material to prepare etorizine hydrochloride simplifies post-processing, improves yield, and ensures that the content of compound III meets pharmacopoeia standards, making it suitable for industrial production.

The present invention relates to 3-chloropropionyl chloride, and in particular to a 3-chloropropionyl chloride synthesis method and a continuous reaction device. After 3-chloropropionic acid and benzyl chloride enter a tubular reactor for reaction, they enter a thin film tubular reactor at the bottom of a reactive distillation tower for reaction aging, and benzoyl chloride is discharged from the bottom. The top 3-chloropropionyl chloride and hydrogen chloride gas are cooled by a primary and a secondary condenser to recover 3-chloropropionyl chloride in a 3-chloropropionyl chloride gas-liquid separator. Hydrogen chloride and acrylic acid react to generate 3-chloropropionyl chloride, and a continuous reaction is carried out. The reaction route of the present invention is simple, free of waste gas, waste water, and solid waste, and the cost is low and safe and controllable. Specifically, the present invention has an atomic utilization rate of 100%, and the cost is reduced from 35,000 yuan / ton to 10,000 yuan / ton; the continuous reaction is adopted to reduce the risk; there is basically no three wastes, and the subsequent treatment problem of by-products such as sulfoxide or phosphorus trichloride is avoided. The invention is a green, environmentally friendly, safe and efficient synthesis model.

The application discloses a method for preparing 4-hexen-3-one by using an aluminum chloride ionic liquid combined with a high gravity reactor, and belongs to the technical field of compound preparation. The method comprises the following steps: adding dichloromethane and an aluminum chloride ionic liquid into a storage tank, stirring and cooling; pumping propionyl chloride into a high gravity reactor, introducing propylene gas, and controlling the reaction temperature; after the reaction is completed, the reaction liquid is separated into layers, and the ionic liquid layer is separated out and recycled; the dichloromethane layer is washed by a sodium carbonate aqueous solution, and then is transferred to a rectifying column; dichloromethane is recovered by normal pressure distillation, and 4-hexen-3-one products are collected by reduced pressure distillation. Compared with the prior art, the application significantly improves the yield of 4-hexen-3-one by optimizing the catalyst system and the reaction conditions, and the catalyst system of the application shows a relatively low activity decline rate in multiple cycles, thereby reducing the production cost and environmental pollution, and having a good industrial application prospect.

The invention provides a preparation method of osimertinib, which belongs to the field of chemical synthesis and comprises the following steps: performing palladium-carbon catalytic hydrogenation reduction on a compound I serving as a raw material; after reduction is finished, hydrogen protection is replaced by nitrogen protection, then 3-chloropropionyl chloride and organic alkali are added, after acylation reaction is finished, direct heating is performed to generate elimination reaction, and a compound II osimertinib is obtained through refining. According to the process, reduction acylation elimination is carried out in the same reaction system, meanwhile, 3-chloropropionyl chloride which is cheaper and easier to obtain is used, acryloyl is eliminated and introduced after acylation, and the whole synthesis process is efficient, economical and environmentally friendly. According to the method, a one-pot strategy is utilized for the first time to combine multiple steps of reactions into one step, the reductive acylation elimination reaction of the compound I is simply and efficiently achieved, and synthesis of osimertinib is completed.

The invention discloses rosin resin and a preparation method thereof, and relates to the technical field of rosin resin, and the rosin resin is prepared from the following components in parts by weight: 100 parts of rosin, 4.2 to 8.4 parts of triphenylphosphine, 40 to 50 parts of allyl glycidyl ether, 18 to 27 parts of p-hydroxyanisole, 500 to 1000 parts of dichloromethane, 34 to 64 parts of triethylamine and 35 to 45 parts of pentafluoropropionyl chloride. The rosin resin prepared by the invention effectively solves the key technical problems of high acid value, poor thermal stability, easy oxidation and crystallization and the like of traditional rosin, the softening point is obviously improved, the acid value is reduced, and the thermal stability and the chemical stability are enhanced; the mechanical strength, toughness, water resistance and corrosion resistance of the modified resin are greatly improved on the basis of maintaining good film-forming property and adhesion of rosin.

The invention discloses a preparation method of an indoxacarb high-purity intermediate, and belongs to the technical field of pesticide synthesis. Mixing chlorobenzene, 3-chloropropionyl chloride and the modified charcoal, stirring and reacting to obtain a first mixed solution; heating and stirring the first mixed solution for reaction to obtain a second mixed solution; adding dimethyl carbonate and anhydrous potassium carbonate into the second mixed solution, mixing and performing reflux reaction to obtain a third mixed solution; and sequentially carrying out reduced pressure distillation and ethanol recrystallization on the third mixed solution to obtain the high-purity indoxacarb intermediate. According to the invention, a molecular imprinting-coordination-sulfur doping synergistic catalysis system is constructed through three-step modification, so that precise recognition and efficient catalysis cooperation are realized, and the reaction selectivity and the product purity are improved. The modified charcoal has excellent stability and can be recycled, the production process is simplified, and the separation difficulty is reduced.

The present invention belongs to the field of high-value conversion of lignin, and specifically relates to the preparation and application of a modified lignin cellulose composite microsphere, comprising adding a phenylpropionyl chloride solution to a low-temperature aminated lignin solution, mixing uniformly, reacting under the protection of an inert gas, collecting the product, and dialyzing to obtain a modified lignin; dissolving the modified lignin in water to obtain an aqueous solution of the modified lignin, then adding sodium carboxymethyl cellulose, mixing uniformly, and then adding dropwise to a low-temperature aluminum chloride aqueous solution to obtain the product. The microspheres prepared by the present invention have uniform lignin dispersion and uniform particle size distribution; the prepared modified lignin cellulose composite microspheres have good adsorption effect on organic dyes in wastewater, and are easy to separate from the wastewater after adsorption; the process is simple, easy to operate, and convenient for industrial application.

The invention belongs to the technical field of pharmaceutical analysis, and particularly relates to a method for separating, detecting and determining an initial raw material SM3 and impurities thereof of ibrutinib. The impurities comprise one or more of propionyl chloride, 3-chloropropionyl chloride and benzoyl chloride. A mobile phase is a phosphate buffer solution as a mobile phase A, acetonitrile is a mobile phase B, a chromatographic column adopts octadecylsilane chemically bonded silica as a filler, and linear gradient elution of high performance liquid chromatography is carried out after pre-column derivatization. And then, according to a chromatogram, an external standard method is adopted to calculate the impurities according to a peak area. The method has the characteristics of good separation degree, good durability, high sensitivity and good reproducibility.

The invention provides a synthetic method of a gemfibrozil impurity A, and belongs to the technical field of chemical synthesis. According to the technical scheme, gemfibrozil is used as an initial raw material and firstly reacts with propionyl chloride in a 1, 2-dichloroethane environment under the catalysis of aluminum trichloride, a product reacts with benzyl bromide in a DMF environment by taking potassium carbonate as an acid-binding agent, an organic phase is collected and dissolved with methanol, and then reduction reaction is performed with sodium borohydride under the catalysis of cerium chloride heptahydrate to obtain gemfibrozil. Collecting to obtain an oily liquid compound, dissolving the oily liquid compound in toluene, carrying out a dehydration reaction under the catalysis of TsOH.H2O, carrying out a hydrolysis reaction on the reaction product in an isopropanol and sodium hydroxide system, carrying out reduced pressure distillation to remove isopropanol, carrying out acid adjustment, extracting with ethyl acetate, drying with sodium sulfate, filtering, concentrating to obtain a white solid, and finally refining and purifying to obtain the 2-(2, 4-dichlorophenyl)-1, 2, 3, 4, 5-tetramethyl-1, 3-pentanediol. A gemfibrozil impurity A finished product is obtained. The method is short in synthetic route, high in process efficiency, convenient to refine and purify and high in yield and purity, and has outstanding technical advantages.

The invention provides a preparation method of prohexadione calcium, and belongs to the technical field of organic synthesis. According to the method, 3, 5-dihydroxybenzoic acid is taken as a raw material, prohexadione calcium is synthesized through four steps of reactions including catalytic hydrogenation reaction, acylation reaction, rearrangement reaction and calcification reaction, and in the acylation reaction, impurities are reduced by controlling the dosage and adding mode of propionyl chloride; the reaction time and temperature are controlled, and the product yield is improved. In the rearrangement reaction, the yield is increased by limiting the pH value, and meanwhile, the industrial production cost can be remarkably reduced by adopting a compound transposition catalyst triethylamine / DMAP; by researching the stability of the compound 3, the reaction conditions of transposition isomerization are determined, and the reaction yield is ensured. Through the reaction and conditions, the yield of the prohexadione calcium in the whole process reaches 65.6%.

The invention relates to the technical field of propionyl chloride production, in particular to an efficient purification device for propionyl chloride production, which comprises a support plate, the lower end of the support plate is fixedly connected with a plurality of support legs, the upper end of the support plate is fixedly connected with a reaction furnace, and the side wall of the reaction furnace is provided with an air inlet and an air outlet. The gas inlet is communicated with an inert gas pipe, a purifying box is fixedly connected to the position, at the gas outlet, of the outer side of the reaction furnace, a plurality of collecting openings are formed in the side wall of the purifying box, and a circulating box is fixedly connected to the lower end of the purifying box. Through the stirring assembly and the water curtain nozzle, the contact efficiency of gas and an alkaline solution is enhanced, the adsorption and dissolution speed of HC gas is increased, efficient gas purification is ensured, a liquid circulation system between the circulation box and the purification box effectively reduces consumption of the solution, cyclic utilization of resources is achieved, the operation cost is reduced, and the device is suitable for popularization and application. The operation is simple, and the occupied area of equipment is small.

This invention belongs to the field of functional coatings technology, specifically relating to a waterborne graphene electrothermal coating. The waterborne graphene electrothermal coating comprises component A, component B, and component C. Component A comprises: waterborne hydroxyl acrylic dispersion, deionized water, wetting and dispersing agent, leveling agent, and defoamer. Component B comprises: waterborne isocyanate curing agent and cosolvent. Component C comprises: amino-modified reduced graphene oxide, composite additive, dispersant, and deionized water. The composite additive is prepared by reacting 3,5-bis(tert-butyl)-4-hydroxyphenylpropionyl chloride sequentially with triethylenetetramine and epoxy-modified carbon nanotubes. The amino-modified reduced graphene oxide is prepared by reacting graphene oxide with N-aminoethyl-3-aminopropylmethyldimethoxysilane followed by reduction. The waterborne graphene electrothermal coating prepared by this invention exhibits excellent electrothermal performance and weather resistance.

The invention relates to the technical field of chemical synthesis, and particularly discloses a cresol trozole trisilane synthesis process, which comprises the following steps: by taking easily available UV-P in the market as a raw material, reacting with cheap and easily available propionyl chloride, reacting with triphenylphosphine to obtain alkene, and finally silanizing to obtain a target product. The whole reaction process has the advantages of cheap and easily available raw materials, low raw material cost, mild reaction conditions, no high-temperature 200 DEG C transposition reaction, strong reaction operability, high conversion rate, few by-products, almost equivalent reaction, no waste of raw materials, high conversion rate, total product yield of more than 80%, conventional three-step reaction, low industrialization requirement and high product yield, and is suitable for industrial production. The method has the advantages of no special requirements on production equipment, high production feasibility, less three wastes and low energy consumption, and is a synthetic route suitable for industrial production.

The invention relates to the field of medicinal chemistry, in particular to a preparation method of efinaconazole. The preparation method comprises the following steps: (1) adding 1, 3-difluorobenzene, S-2-chloropropionyl chloride and a catalyst into an organic solvent A, uniformly mixing, and heating for reaction to obtain a compound 1; (2) adding a compound 1, 4-methylene piperidine into an organic solvent B, and reacting to obtain a compound 2; and (3) adding the compound 2, trimethyl sulfoxide iodide, alkali and 1H-1, 2, 4-triazole into an organic solvent C, mixing, and reacting to obtain the efinaconazole. The preparation method has the advantages of easily available raw materials, simple process and mild reaction conditions, and is suitable for industrial production.

The invention discloses a synthesis method of 3-chloropropionyl chloride, and relates to the field of fine chemical engineering. Acrylic acid and bis (trichloromethyl) carbonate are used as raw materials and react under the action of a catalyst to generate acryloyl chloride, meanwhile, generated hydrogen chloride and double bonds in the acryloyl chloride are subjected to an addition reaction, and finally 3-chloropropionyl chloride is obtained. Acrylic acid and triphosgene are adopted as raw materials, the price is low, safety is high, and the method is suitable for industrial production; the reaction is a one-pot method, and the operation is simple. The hydrogen chloride gas generated in the synthesis method is directly recycled, so that the emission of waste gas is reduced, the method is economical and environment-friendly, the atom utilization rate is high, the unique by-product carbon dioxide of the reaction can be directly discharged after being simply treated, no by-products such as sulfur dioxide and phosphorous acid are generated, and the environment-friendly cost is low. After the synthetic product is simply distilled, the content of the product reaches 99% or above, the yield is close to 90%, and the purpose of simply synthesizing the high-purity 3-chloropropionyl chloride with high yield is achieved.

The invention belongs to the technical field of pharmaceutical analysis, and particularly relates to a method for separating and determining ibrutinib SM3 and impurities thereof based on gas chromatography. The impurities comprise any one or more of acrylic anhydride, trichlorotoluene, propionyl chloride, 3-chloropropionyl chloride, benzoyl chloride, acrylic acid and benzoic acid; the ibrutinib SM3 and impurities jointly form a composition to be detected. According to the method, (5% phenyl)-diphenylmethylsiloxane is adopted as a chromatographic column of a stationary liquid, or other stationary liquids with the same polarity are adopted; the ibrutinib SM3 and impurities of the ibrutinib SM3 are separated by adopting temperature programming; the temperature programming setting is as follows: the initial temperature is 35 + / -5 DEG C and is maintained for 5 + / -1 minutes, and the temperature is raised to 210 + / -10 DEG C at the rate of 30 + / -5 DEG C / min and is maintained for 8 + / -2 minutes. The method provided by the invention can effectively separate, identify and quantify various related substances in ibrutinib SM3, and has the advantages of short separation time, strong specificity, high sensitivity and good durability.

The invention discloses an anti-aging rubber material and a preparation method thereof, and relates to the technical field of high polymer materials. When the anti-aging rubber material is prepared, 4, 4 '-diaminodiphenylamine and 3, 5-bis (tert-butyl)-4-hydroxybenzene propionyl chloride are subjected to a reaction to prepare an anti-aging agent; reacting the maleic anhydride grafted ethylene propylene diene monomer with an anti-aging agent to obtain modified ethylene propylene diene monomer; reacting the carboxylated carbon nano tube with 3-(diphenylphosphino) propylamine to prepare a pre-modified carbon nano tube; reacting the pre-modified carbon nano tube with 2-(3-chloropropyl)-4, 6-dimethyl-1, 3, 5-triazine, so as to obtain a modified carbon nano tube; mixing the modified ethylene propylene diene monomer, the modified carbon nanotubes, zinc oxide, stearic acid, carbon black, paraffin oil, sulfur, an accelerant TMTD and an accelerant M, and performing hot pressing to obtain the anti-aging rubber material. The anti-aging rubber material prepared by the invention has good anti-aging, flame-retardant, antistatic and mechanical properties.

The invention discloses a method for detecting a related substance 3-chloropropionic acid in osimertinib starting material 3-chloropropionyl chloride, which comprises the following steps: reacting a sample with C1-C6 alkyl primary amine to preferentially convert 3-chloropropionyl chloride into an amide derivative; then adding an acyl chloride reagent and an alcohol esterification reagent, so that 3-chloropropionic acid is subjected to esterification reaction; then adding organic alkali for neutralization to obtain a stable test solution; and finally analyzing and quantifying through gas chromatography. Through step-by-step derivatization design, the interference of the main component 3-chloropropionyl chloride is thoroughly eliminated by using the preferential reaction of C1-C6 alkyl primary amine, then 3-chloropropionic acid is subjected to esterification reaction, and hydrochloric acid generated in the reaction is completely neutralized by adding organic alkali, so that the hydrolysis of the target derivative methyl 3-chloropropionate is effectively inhibited, and the stability of the target derivative methyl 3-chloropropionate is ensured. The method has the advantages of strong anti-interference performance, high accuracy, high sensitivity (the limit of quantitation is less than or equal to 0.03%), simple operation and easy industrial application.

The invention discloses a hydrogen peroxide and salicylic acid double-response fluorescent probe as well as a preparation method and application thereof, and belongs to the technical field of fluorescent probes. The preparation method comprises the following steps: dissolving (E)-2-amino-6 '-(diethylamino)-4'-[2-((E)-1, 3, 3-trimethylindoline-2-subunit) ethylidene]-1 ', 2', 3 ', 4'-tetrahydrospiro [isoindoline-1, 9 '-xanthene]-3-ketone in anhydrous acetonitrile, adding NaH and DMAP, uniformly stirring, then adding 3-[6-(4, 4, 5, 5-tetramethyl-1, 3, 2-boron dioxolane-2-yl)-1, 2, 4-triazole-2-yl)-1, 3, 4-triazole-2-yl]-1, 3, 4-triazole-2-yl]-1, 3, 4-triazole-2-yl]-1, 3, 4-triazole-2- adding 2, 3-dioxo-1H-benzo [de] isoquinoline-2 (3H)-yl] propionyl chloride, and reacting to obtain the target fluorescent probe. According to the probe, H2O2 and SA recognition sites are orthogonally coupled to the same parent nucleus, so that it is ensured that all recognition units synchronously reach a target microenvironment at a constant stoichiometric ratio, high sensitivity and near-infrared emission characteristics are achieved, autofluorescence interference of plant tissues is effectively avoided, and the detection sensitivity is high. Accurate in-situ imaging and dynamic analysis of the space-time evolution process of H2O2 and SA in plant cells are achieved, and the method has wide application prospects in the fields of plant immunology, analytical chemistry, life science and the like.

The invention provides a method and a device for continuously producing propionyl chloride, the device comprises two-stage reaction and phase-splitting steps and equipment, the heavy-phase byproduct phosphorous acid of the two-stage phase splitting is refluxed to the first-stage reaction, propionic acid generated in the propionyl chloride rectification byproduct refining step is refluxed to the second-stage reaction, the first-stage propionic acid is fed from a tail gas absorption tower, and the second-stage propionic acid is fed from a tail gas absorption tower. Absorbing phosphorus trichloride volatilized in the first-stage reaction and the second-stage reaction, and then entering a first-stage reaction kettle; the first-stage phosphorus trichloride is excessive, propionic acid can completely react, and the problem that phosphorous acid contains propionic acid is solved; the second-stage propionic acid is excessive relative to the residual phosphorus trichloride in the first-stage reaction, so that the phosphorus trichloride can react completely, and the problem that the phosphorus trichloride and the propionyl chloride are difficult to separate is solved. Phosphorus trichloride volatilized by the two sections of reaction kettles reacts with fed propionic acid in the tail gas absorption tower to achieve the purpose of chemical absorption, so that the loss of phosphorus trichloride is reduced, the yield of phosphorus trichloride is improved, and the production cost of labor, energy consumption and the like is reduced.

This invention relates to a method for preparing the CYP11B2 inhibitor BAXDROSTAT. Specifically, this invention provides two preparation methods. Method 1: Baxdrostat is obtained by condensing 4-halo-6,7-dihydroisoquinoline-8(5H)-one with S-tert-butylsulfinamide aldehyde ketone, followed by reduction with sodium borohydride, then reaction with pinacol diboronate, followed by Suzuki coupling reaction, deprotection, and reaction with propionyl chloride. Method 2: The product (S)-N-(4-halo-6,7-dihydroisoquinoline-8(5H))-tert-butylsulfonylimide from step 2 of Method 1 is first deprotected, then reacted with 6-bromo-1-methyl-3,4-dihydroquinoline-2(1H)-one via Suzuki coupling reaction, and then reacted with allyl chloride.

The invention relates to the technical field of wet tissues, in particular to a wiping wet tissue for rust-proof maintenance, which is sequentially provided with a rust-proof wiping layer, a middle functional layer and a clean wiping layer from top to bottom, the preparation process of the modified paraffin comprises the following steps: dissolving 3, 5-bis (tert-butyl)-4-hydroxybenzene propionyl chloride in a xylene solution to obtain a hindered phenol xylene solution, mixing the hindered phenol xylene solution and 3-aminopropyltriethoxysilane, heating to 80 DEG C, carrying out heat preservation reaction for 6 hours, and purifying to obtain a coupling agent grafted hindered phenol antioxidant; grafting polyethylene glycol: mixing the coupling agent grafted hindered phenol antioxidant, polyethylene glycol and deionized water, carrying out ultrasonic reaction at 50 DEG C for 6 hours, evaporating to remove a solvent, and drying to obtain a modified additive; paraffin and the modified additive are blended for 1-3 hours at the temperature of 60-80 DEG C, modified paraffin is obtained, and the use performance of the anti-rust additive of the modified paraffin is improved.