This invention discloses a medical gel for
skin damage repair and its application, belonging to the field of
skin repair technology. The medical gel is a
gelatin-based gel containing a low molecular weight complex
polysaccharide. This low molecular weight complex
polysaccharide is obtained by mixing
Dendrobium nobile,
Dryopteris crassirhizoma, and Spartina alterniflora in a specific ratio, followed by
degreasing with
petroleum ether and
ethanol, ultrasonic extraction,
ethanol precipitation, and
ultrafiltration purification to obtain a low molecular weight complex
polysaccharide with a molecular weight less than 5000 Da. This invention also discloses the application of the aforementioned low molecular weight complex polysaccharide in the preparation of
skin repair-promoting drugs or medical gels, which is particularly suitable for repairing full-thickness
skin damage caused by mechanical injury. Its
mechanism of action includes promoting the proliferation and migration of skin fibroblasts and
angiogenesis of vascular endothelial cells. Therefore, the medical gel prepared by this invention has a significant wound-healing effect and can effectively accelerate the repair process of full-thickness
skin damage.