39results about How to "Efficient reaction conditions" patented technology

The invention belongs to the technical field of food processing and relates to sea worm seasoning and a manufacturing method thereof. The sea worm seasoning comprises, by weight parts, 70-105 parts of refined salt, 20-30 parts of natural yeast extract, 8-12 parts of clam nectar, 20-28 parts of youxiantai, 25-35 parts of white sugar, 4-6 parts of natural HVP, 0.3-0.6 part of allicin, 20-30 parts of corn starch, 12-18 parts of bonito powder, 6-12 parts of sea worm juice and 0.4-0.8 part of sodium glutamate and further comprises 60-120 parts of sauce. The sea worm seasoning is in a powder or sauce shape. The sea worm powder is formed by raw material pretreatment, enzymolysis, reaction and spray drying; and the sea worm sauce is formed by raw material pretreatment, mixing, reaction and forming. The product is free of any abnormal smell and fishy smell and is particularly outstanding in delicious taste; all natural young seafood raw materials are adopted, no chemical substance is added in the production process, and the sea worm seasoning is all natural and healthy.

The invention relates to non-animal-derived LMW (low molecular weight) heparin, a preparation method therefor and application of the non-animal-derived LMW heparin. The preparation method disclosed bythe invention comprises the steps of performing a one-step chemical method and a variety of enzyme catalysis methods in order: extracting an exopolysaccharide K5CPS, subjecting the exopolysaccharideK5CPS to chemical-method N-deacetylation / N-sulfation modification, and then, carrying out partial depolymerization in a buffer solution through heparinase III; and subjecting obtained LMW products toenzyme-method C-5 epimerization / 2-O-sulfation modification, 6-O-sulfation modification and 3-O-sulfation modification sequentially, thereby obtaining a product with anti-FXa and anti-FIIa activity. The invention provides a novel method for preparing the LMW product with typical structure characteristics of the heparin and remarkable anticoagulation activity. According to the method, raw materialsare non-animal-derived, the quality is controllable, the risk of contamination is low, adopted reaction conditions are mild and efficient, the obtained product is easy to separate, and large-scale preparation of the LMW heparin with good structural homogeneity and high anticoagulation activity can be achieved.

The invention belongs to the field of nitrate reduction in water, and particularly relates to a nitride catalyst for efficient photocatalytic reduction of nitrate in water and a water treatment methodthereof. The method comprises the following steps of preparing the nitride catalyst for the photocatalytic reduction of the nitrate in the water by adopting different methods; putting the prepared catalyst into nitrate-containing industrial wastewater to be treated, and conducting photocatalytic reduction of the nitrate in the water under ultraviolet light irradiation. The catalyst for the photocatalytic reduction of the nitrate in the water is a nitride type, and includes transition type nitride, covalent type nitride, nitride of different morphologies, defect nitride, nitride loaded with ametal and a metal quantum dot, a composite of nitride and a metal oxide and nitride loaded on different carriers. The method has the advantages of simple equipment, easy control, mild reaction conditions and the like; the prepared nitride catalyst can efficiently and stably remove the nitrate in sewage, and have good stability.

The invention belongs to the technical field of tissue engineering, and discloses a method for building a biological activity gel film layer on the surface of a biological material containing alkynyl.The method comprises the following steps that (1) performing reaction on a high molecular material containing alkynyl and biological active macromolecules containing azide groups to obtain a high molecular material with biological active macromolecules; (2) performing reaction on the biological active macromolecules containing alkynyl and a high molecular material bonded with biological active macromolecules to obtain a high molecular material bonded with an active layer; (3) repeating the step (1) or the steps (1) to (2) to obtain the high molecular materials bonded with active layers with different thickness on the surface; (4) performing reaction on micromolecules containing azide groups or alkynyl and the high molecular materials in the step (3) to obtain a product. The method provided by the invention is simple, flexible and efficient; the reaction conditions are mild; the thickness of the biological active layer can be controlled; no limitation exists on the material form morphological structure; the application range is wide; the combination of the biological active layer and the high molecular materials is stable and firm.

The invention discloses a catalyst for one-step preparing cyclohexanone by hydrogenation of water phase phenol, and its preparation method. The preparation method comprises the following steps: adding Cr(NO3)3.9H2O, HF and terephthalic acid into deionized water, then adding into a hydrothermal reaction vessel to react for 7-9 hours at the temperature of 210 DEG C-230 DEG C; cooling to the room temperature and filtering, vacuum drying to obtain an activated organometallic framework structure material; taking the framework structure as a carrier, loading the reduction state metal Pd nano particles to obtain a catalyst for one-step preparing cyclohexanone by hydrogenation of water phase phenol; the catalyst possesses two functions of Lewis acid sites and hydrogenation active sites. The preparation method of the invention has the characteristics of environmental protection, mild reaction condition, high activity and selectivity, good stability, simple products separation and the like. Thepreparation method for the catalyst is simple, and a reaction solution and the catalyst are easy to separate.

The invention discloses a supported cyclometalated iridium catalyst, a preparation method thereof and application of the supported cyclometalated iridium catalyst in dehydrogenation reaction of dihydroindolines compounds; the catalyst is loaded with a pyrene-loaded cyclometalated iridium complex by taking a multiwalled carbon nanotube as a carrier; in the cyclometalated iridium complex, an iridium atom is taken as a coordination center and 4-methoxy-n-[1-(4-hydroxyphenyl)]-phenylamine and pentamethylcyclo penta dience as ligands. The catalyst disclosed by the invention is simple in preparation method and short in preparation cycle and is capable of realizing the dehydrogenation reaction of the dihydroindolines compounds in green solvent (mixed solvent of water and trifluoroethanol); the reaction condition is mild, safe, green and efficient; the catalyst disclosed by the invention can be recovered through simple centrifugal separation, and the excellent catalytic performance of the catalyst is still kept after the catalyst is reused for multiple times.

The invention discloses a preparation method of a coupling aromatic compound, which comprises the following steps of taking non-functional aromatic hydrocarbon and / or halogenated aromatic hydrocarbon as a raw material, taking an oxime ether cyclopalladated complex as a catalyst, reacting for 6-48 hours in an organic solvent at a temperature of 100-160 DEG C under the inert atmosphere under the action of alkali, and post-processing reaction liquid after the end of reaction to obtain the coupling aromatic compound. The oxime ether cyclopalladated complex is a complex formed by reacting metal palladium salt with an organic nitrogen ligand in a methanol solvent at a room temperature; and the metal palladium salt is lithium tetrachloropalladate; and the organic nitrogen ligand is 4-hydroxy acetophenone oxime. The preparation method has the beneficial effects that when the oxime ether cyclopalladated complex is selected as the catalyst to replace a traditional palladium / phosphorus composite catalyst, the reaction condition can be milder and more efficient, so that the use of the ligand is greatly reduced; and the halogenated aromatic hydrocarbon which is lower in activity and cost and is easily obtained can also be used as a substrate in the reaction.

The preparation method of α,α-disubstituted isochroman compounds, adopts easily synthesized α-monosubstituted isochroman compounds with various structures as raw materials, and directly synthesizes them with nitromethane in one step to obtain α,α-disubstituted isochromans Chromatic compounds. The method used in the invention has short reaction steps, mild reaction conditions, high efficiency and simple operation. In the preparation method, the α-position carbon C-H bond of the α-monosubstituted isochroman compound is directly formed into a C-C bond, which avoids the use of intermediates with lengthy synthesis steps. It is consistent with the current pursuit of the idea of ​​atom economy and sustainable green synthetic chemistry. The preparation of α, α-disubstituted isochroman compounds can undergo a series of chemical transformations to generate various substituted isochroman derivatives, which have great application potential in the preparation of drugs and active natural products.

The invention belongs to the technical field of organic chemistry, and discloses a polyacetylenic compound and a preparation method thereof. The method comprises the following steps: (1) under the protection of an inert gas, mixing a diacetylene halide compound and a binary sulphonamide compound in a catalytic system and an organic solvent, reacting, and cooling to obtain a reaction mother liquid; (2) adding the reaction mother liquid into a precipitator for precipitating, collecting a precipitated, and drying to constant weight to obtain a polyacetylenic compound. The preparation method disclosed by the invention is simple; the reaction is efficient; the group tolerance is high; a plurality of functional groups can be intruded into monomers; the prepared polyacetylenic compound contains a carbon-carbon triple bond, and has important application to serving as an intermediate in a further reaction; moreover, the compound is easy to hydrolyze, and has a very promising prospect in the aspects of environmentally friendly chemistry, green chemistry and the like, such as a degradable material.

The invention discloses a ferrocene bonding chromatographic stationary phase and a preparing method thereof. The ferrocene bonding chromatographic stationary phase is obtained in the way that under the protection of inert atmosphere in an organic solvent, azodiisobutyronitrile is added dropwise to 3-mercaptopropyl silanized inorganic matrix microspheres and vinylferrocene to serve as the initiator, reaction is conducted for 18-36 h at 80-120 DEG C, and then cooling, filtration, washing and drying are conducted. The preparing process is simple, cost is low, reaction materials are easy to obtain and have wide sources, and the ferrocene bonding chromatographic stationary phase can be directly used without any modification; the prepared ferrocene bonding chromatographic stationary phase is a universal hydrophobic interaction chromatographic stationary phase, has high separation selectivity for most compounds, and has high application value and potential.

The invention belongs to the technical field of preparation of selenium-containing polymers, and discloses a method for preparing polyselenourea / polyselenoamide through multi-component polymerizationof elemental selenium, isonitrile / alkyne and amine. The method comprises: carrying out a reaction on elemental selenium, a binary triple bond compound and a diamine in an organic solvent under an inert atmosphere, and subsequently treating to obtain a selenium-containing polymer, wherein the binary triple bond compound is binary isonitrile or binary alkyne, and the selenium-containing polymer is polyselenourea or polyselenoamide. According to the present invention, the method has characteristics of mild reaction conditions, high efficiency, energy saving, no catalyst, no by-product generation,atomic economy, green chemistry, low monomer toxicity, high atom utilization rate and high yield (more than or equal to 90%); the group has strong tolerance, and a variety of functional groups can beintroduced into the monomer; and the polyselenourea / polyselenoamide is stable, and can be degraded under specific conditions.

The invention discloses a highly-hyperbranched cationic polysaccharide derivative containing a dendritic polyamidoamine group and a preparation method of the highly-hyperbranched cationic polysaccharide derivative. The highly-hyperbranched cationic polysaccharide derivative containing the dendritic polyamidoamine group has a structural formula shown by a formula (I); and the highly-hyperbranched cationic polysaccharide derivative is synthesized by selectively coupling dendritic polyamidoamine (PAMAM D3 or D4) to a hyperbranched polysaccharide chain through an efficient nitrine-alkyne click reaction method. The preparation method disclosed by the invention is mild in reaction condition and has high reaction efficiency and selectivity at the same time. The prepared cationic polysaccharide derivative containing the dendritic polyamidoamine group has a characteristic of a highly-hyperbranched structure, can well form an electropositive nano-composite with siRNA, is favorable for carrying siRNA to enter cells, can improve the transfection efficiency of siRNA to genes, is expected to be used as a gene carrier and has a great prospect of application.