33 results about "Hydrophobic ion" patented technology

Methods for encapsulating water-soluble biologic and small molecule active pharmaceutical ingredients (APIs) into nanoparticles by applying nanoprecipitation techniques and ion-pairing the nanoparticles with hydrophobic counterions to produce new API salts that exhibit altered solubilities are presented.

The invention discloses a novel liquid-holding particle type iodine-loaded antibacterial agent-ionic liquid gel iodine-loaded microsphere preparation method, which comprises the following steps: by taking polymethyl methacrylate as a network, a hydrophobic ionic liquid as a dispersion medium, methyl methacrylate as a monomer and azodiisobutyronitrile as an initiator, embedding molecular iodine in situ in the network, and preparing the novel liquid-holding particle type iodine-loaded antibacterial agent-ionic liquid gel iodine-loaded microsphere. The ionic liquid gel iodine-loaded microspheres are prepared. The ionic liquid cation imidazolyl group in the microbial agent can vertically act on a phospholipid bilayer on a bacterial cell membrane, and the hydrophobic end can destroy the complete structure of the cell membrane due to electrostatic interaction, so that substances outside the cell enter the cell or substances inside the cell leak out, and the cell is inactivated. Meanwhile, surface iodine in the ionic liquid gel iodine-loaded microspheres has an antibacterial effect, and the ionic liquid gel iodine-loaded microspheres and the surface iodine jointly inhibit growth of bacteria. The novel liquid-holding particle type iodine-loaded antibacterial agent-ionic liquid gel iodine-loaded microsphere is a novel solid-liquid composite polymer antibacterial material, and has the characteristics of simple preparation method, wide application range, excellent antibacterial performance and the like.

The invention discloses a method for separating rhenium from a rhenium-rich solution containing molybdenum and tungsten. The method comprises the following steps: extracting a rhenium-rich raw material solution containing ReO4 <-> and impurity ions by using an extraction agent containing hydrophobic ionic liquid to obtain an organic extraction phase containing ReO4 <-> and a raffinate phase containing the impurity ions; wherein the solvent of the raw material solution is water, and the impurity ions comprise one or two of MoO4 < 2-> and WO4 < 2->; the hydrophobic ionic liquid is composed of positive ions and negative ions, the anions are selected from one or more of halide ions, borate anions, carboxylate anions, carbonate anions, nitrate ions, nitrite ions, sulfate anions, sulfite anions, sulfonate anions, phosphate anions, phosphite anions, thiocyanate anions and amino acid ions. The method is high in separation efficiency, simple in technological process, easy to amplify, small in extraction agent loss, capable of being recycled and suitable for industrial production.

The application discloses a composite gel and a preparation method thereof, a strain sensor and application of the strain sensor. The preparation method of the composite gel comprises the following steps: mixing and matching raw materials including a hydrophilic polymerizable monomer, an initiator, a crosslinking agent, water, a hydrophobic ionic liquid and an amphiphilic metal salt into a precursor solution, and preparing the composite gel through a polymerization reaction. By introducing the amphiphilic metal salt as a molecular bridge, the compatible connection of the hydrophilic network and the hydrophobic ionic liquid can be realized. By introducing the relatively inexpensive water phase, the use amount of the hydrophobic ionic liquid can be reduced, and the cost can be effectively controlled. By adjusting the ratio of the hydrophobic ionic liquid and the water, the Young's modulus can be accurately controlled in a wide range to match different human tissues. The obtained composite gel has excellent anti-drying, anti-freezing and environmental stability, and simultaneously has low hysteresis and self-adhesion characteristics. The composite gel is suitable for the strain sensor, and stable and reliable dynamic monitoring can be realized. Moreover, the process is simple, the conditions are mild, and the composite gel is easy to produce on a large scale.

The invention relates to a composite electrostatic eliminator and a preparation method thereof, and relates to the technical field of chemical assistants, the composite electrostatic eliminator comprises isopropanol, cetrimonium chloride, fatty alcohol-polyoxyethylene ether, polyvinyl alcohol, polyethylene glycol, triethanolamine, isothiazolinone, propylene glycol, disodium ethylene diamine tetraacetate, essence, modified carbon nanotubes, and a hydrophobic ionic liquid. The water-based polyurethane resin is prepared from water-based furan polyurethane, non-ionic water-based furan polyurethane, bismaleimide and the balance deionized water. Modified carbon nanotubes and hydrophobic ionic liquid are uniformly dispersed in a coating through electrostatic anchoring of cetrimonium chloride and emulsification of fatty alcohol-polyoxyethylene ether, an electron tunneling network in a low-humidity environment is formed, and it is ensured that the electrostatic dissipation capacity of the coating of the electrostatic elimination agent in the low-humidity environment is improved; a dynamic cross-linked network is formed through a Diels-Alder reaction generated by the nonionic waterborne furan polyurethane and the bismaleimide, a conductive path in a damaged area can be rebuilt under external thermal excitation, and the functional durability is improved.

The present invention relates to a depot composition comprising calcium chloride in the interior of microspheres. The depot composition according to the present invention can control the excessive release of the effective ingredient contained in the interior of the microspheres at the initial stage of the depot injection by using calcium chloride as a cationic salt. In addition, the composition has excellent suspendability and a very small amount of residual solvent, and thus the effect of the effective ingredient can be uniformly and continuously obtained even if the user administers it in the form of an injection. In addition, an improved medical therapy of semaglutide can be provided by adjusting the dose of semaglutide or tirzepatide through the depot dosage form.

The application belongs to the technical field of sensors, and discloses a composite gel material, a preparation method thereof and an ion electric sensor. The composite gel material comprises an upper hydrophobic ion gel layer, a lower hydrophobic ion gel layer and a hydrogel layer; the hydrogel layer is located between the upper hydrophobic ion gel layer and the lower hydrophobic ion gel layer, forming a sandwich structure. The composite gel material can effectively slow down the water loss of the core hydrogel layer, maintain the high sensitivity of the hydrogel layer as a sensing medium, and has good interface bonding force between the layers of the material.

The invention relates to an octreotide deoxycholate hydrophobic ion pair solid dispersion and a preparation method thereof, and belongs to the technical field of medicines. The octreotide deoxycholate hydrophobic ion pair solid dispersion is composed of a compound formed by octreotide acetate and an anionic surfactant and a solid dispersion carrier material, the anionic surfactant is deoxycholate, and the solid dispersion carrier material is one of an enteric-coated carrier and a hydrophilic carrier. The octreotide and deoxycholate form hydrophobic ion pairs, so that the lipophilicity and transmembrane permeability of the octreotide are improved, the stability and bioavailability of the octreotide in an oral administration system are enhanced, meanwhile, the preparation process is simple, the cost is low, and compared with a self-emulsifying preparation, the preparation process is simplified, the dosage is flexible, and the preparation cost is low. And meanwhile, the product has better stability, is easier to store and transport, and is suitable for industrial production.

The phencynonate hydrochloride sustained release tablet comprises the following components: phencynonate hydrochloride, a sustained release material, dodecanal, a 40% dimethylamine aqueous solution, sodium triacetoxyborohydride, an adhesive, a filler and a lubricant, the invention also relates to a preparation method of the phencynonate hydrochloride sustained release tablet. The sustained-release material is added to delay the release of the water-soluble phencynonyl hydrochloride, then lauric aldehyde and dimethylamine are further added to react in the presence of a reducing agent sodium triacetoxyborohydride to generate high-fat-solubility, low-toxicity and stable tertiary amine, and the tertiary amine and phencynonyl ester cations in the phencynonyl hydrochloride can form hydrophobic ion pairs; the release rate from the preparation to a water phase is slowed down, slow release of the medicine is realized, the action time is prolonged, the administration frequency is reduced, and the compliance to people taking vehicles for a long time is improved.

The invention discloses a cathode material and a preparation method thereof, a cathode and a method for recovering metals in copper anode slime. The cathode material is prepared from a hydrophobic ionic liquid, a porous conductive material and a packaging material, pore channels of the porous conductive material are filled with the hydrophobic ionic liquid; the packaging material is coated on the outer side of the porous conductive material and is used for packaging the hydrophobic ionic liquid in pore channels of the porous conductive material. The cathode material disclosed by the invention is used for preparing a cathode, the capacitance is large, the cathode material can be used for recovering metal ions in copper anode slime, the operation is simple, the adsorption capacity is large, the cathode material can be recycled, and the operation cost is low.

A photocatalytic method for removing antibiotics from wastewater, belonging to the field of wastewater treatment technology, addresses the technical problems of complex photocatalyst recovery processes, poor catalyst stability in water, and low degradation efficiency under visible light during the photocatalytic degradation of antibiotics in wastewater. This invention uses a hydrophobic ionic liquid as the organic component, forming a hybrid material (photocatalyst) through ionic bonds with inorganic components such as organometallic frameworks and polyoxometalates. This material can extract antibiotics from wastewater, and through the synergistic effect of the organometallic framework, polyoxometalates, and ionic liquid, photodegradation of antibiotics is achieved under visible light. The photocatalyst exists in a water-insoluble liquid state, thus allowing for sedimentation and stratification; the lower layer can be collected for recovery and reuse. This invention achieves effective degradation of antibiotics under visible light and features a simple preparation process, reusable catalyst, and no secondary pollution of water bodies by the reaction system.

The present disclosure provides a solution containing a high-purity ion pair [EDMPC]+[anionic surfactant]-. The solution containing a high-purity ion pair [EDMPC]+[anionic surfactant]- can be obtained by introducing a salt of [EDMPC]+ into an anion exchange resin that has adsorbed the [anionic surfactant]-.

The invention relates to the field of polyolefin materials, in particular to double modified talcum powder, conductive polyolefin master batch and a preparation method. The preparation method comprises the following steps: modifying talcum powder with a silane coupling agent to obtain silane modified talcum powder, and then modifying the silane modified talcum powder with a hydrophobic ionic liquid to obtain the dual modified talcum powder. The dual-modified talcum powder is used for a polyolefin matrix containing a carbon nanotube (CNT), so that the electrical conductivity of polyolefin cannot be reduced, and the electrical conductivity of polyolefin can be improved.

This application relates to the field of traditional Chinese medicine pharmaceutical technology, and discloses a traditional Chinese medicine for treating diabetic neuropathy and its preparation method. The traditional Chinese medicine is prepared from Coptis chinensis, Corydalis yanhusuo, Schisandra chinensis, Cornus officinalis, Astragalus membranaceus, and Cinnamomum cassia. The preparation method includes: low-temperature differential pretreatment of the raw materials; gas-phase assisted mechanical activation of components A and C under pressurized carbon dioxide environment, utilizing in-situ generation of carbamate intermediates in the gas phase to reduce lattice energy; subsequently, component B is added and pulsed milling is performed, directionally assembling into a hydrophobic ion-pair complex through a thermodynamically driven ligand substitution reaction; finally, the pressure and temperature are increased in situ to convert the reaction medium into a supercritical fluid for integrated extraction. This invention achieves the transformation of the active ingredient from a hydrophilic to a lipophilic chemical form through a gas-phase activation and stepwise substitution strategy, enabling it to effectively penetrate the blood-nerve barrier. Simultaneously, the low-temperature, anaerobic environment throughout the process effectively avoids the degradation of heat-sensitive components.

The application discloses an electrically activated cyclic flow membrane electrically controlled ion selective separation system and method. A water solution containing target ions and a hydrophobic ion extractant with ion selective separation function are simultaneously flowed through a tilted tube type extraction separator in a double-layer parallel flow mode, a directional electric field between upper and lower inner wall electrode plates of the extraction separator is used to drive the target ions in the water solution to selectively diffuse to the side of the hydrophobic ion extractant, separation of the target ions is realized, then the extractant extracting the target ions and a regenerated water solution are flowed through another tilted tube type extraction separator in a double-layer parallel flow mode, and under the action of a reverse electric field, the target ions are driven to diffuse into the regenerated water solution, regeneration of the ion extractant is realized, and the above-mentioned cyclic flow membrane system is used to realize selective continuous separation of the target ions in the water solution. The application has the advantages of small ion diffusion resistance, fast separation rate, high selectivity and low cost.

The invention discloses a semeglutide self-emulsifying composition and application thereof, and belongs to the technical field of biological medicine. According to the invention, a hydrophobic ion pairing (HIP) technology is utilized, the semeglutide and counter ions are firstly prepared into a hydrophobic ion pair compound to improve the lipid solubility of the semeglutide, and then the semeglutide hydrophobic ion pair compound is loaded into the self-microemulsion as an active component to realize efficient oral delivery of the semeglutide. Based on a hydrophobic ion pairing technology and a self-microemulsion delivery technology, a novel simple and cost-effective semeglutide oral delivery method is constructed, and the method has a good application prospect.

The application provides a method for synthesizing ionic liquid nanodroplets through solute-induced phase separation, and relates to the technical field of nanomaterials. The method generates a hydrophobic ionic liquid in situ through an ion exchange reaction in a homogeneous system, and constructs nanodroplets by using the nucleation and growth law of the ionic liquid from nothing to something. The method effectively solves the technical problems of wide droplet distribution, large size and easy coalescence of droplets in the traditional "top-down" method.

This invention provides an electrolyte, its preparation method, and a metal-air battery, specifically relating to the field of metal-air battery technology. The electrolyte comprises a hydrophobic ionic liquid solution containing a first metal salt and a hydrophilic ionic liquid solution containing a second metal salt; the volume ratio of the hydrophobic ionic liquid solution containing the first metal salt to the hydrophilic ionic liquid solution containing the second metal salt is 1:(1-5). This electrolyte effectively regulates the solubility and stability of the metal salt, ensuring the conduction of metal ions during the electrochemical reaction. During the electrochemical reaction, the electrolyte facilitates gas diffusion and redox reactions at the positive electrode, ensuring electrode wettability and catalyst stability; simultaneously, it promotes metal deposition and dissolution, reducing uneven metal ion deposition and dendrite growth, improving battery cycle stability, suppressing side reactions, reducing metal electrode corrosion and oxidation, and extending battery life.

Composition for heat storage, comprising at least one hydrophobic ionic liquid containing an organic cation and a tetrafluoroborate anion, wherein the cation is selected from the group of heterocyclic, nitrogen-containing cations with alkyl substituents, whose chain lengths lie between two and eight carbon atoms, and wherein the composition has a specific heat capacity of more than 0.9 joules per gram and kelvin within a temperature range of seventy-five to six hundred kelvin.

The invention provides a method for separating 1, 3-dihydroxyacetone and glycerol. The method provided by the invention comprises the step of performing multi-stage extraction on a raw material solution containing 1, 3-dihydroxyacetone and glycerol by using a hydrophobic extraction agent, wherein a solvent in the raw material solution comprises water; the hydrophobic extraction agent comprises a hydrophobic ionic liquid and / or a hydrophobic polar organic solvent. The method provided by the invention has a better separation effect on 1, 3-dihydroxyacetone and glycerol with similar structures, and the two separated substances have higher yield and purity.

The present invention relates to a hydrophobic ion pairing complex composition for oral administration, the composition comprising a peptide drug and a counterion, and a method for preparing same. More specifically, the present invention relates to a hydrophobic ion pairing (HIP) complex composition comprising two or more kinds of counterions bound to a peptide drug, and a method for preparing same.

This invention discloses a gas-sensitive hydrogel electrolyte, its preparation method, a gas-sensitive sensor, and its application. The gas-sensitive hydrogel electrolyte comprises a polymer network and zinc trifluoromethanesulfonate, a hydrophobic ionic liquid, and water distributed within the polymer network. The hydrophobic ionic liquid has hydrophobic groups, and at least some of these hydrophobic groups are distributed on the surface of the gas-sensitive hydrogel electrolyte. This effectively suppresses the disproportionation side reaction between NO2 and water, thereby guiding more NO2 molecules directly to the electrode surface to participate in electrochemical reduction. This structure also improves electrode interface compatibility and charge transport efficiency. The addition of zinc trifluoromethanesulfonate enhances the stability of the ion-conducting network. Therefore, the gas-sensitive hydrogel electrolyte can achieve highly sensitive detection of NO2 at the ppb level, possessing a high signal-to-noise ratio, fast response recovery, and good stability, and can be used to construct a high-performance nitrogen dioxide gas sensor.

The application discloses a kind of vanadium residue extraction gallium processes based on microwave intensification selective precipitation-ion liquid circulation, belong to metal resource recovery technical field.The present application provides a kind of vanadium residue extraction gallium processes based on microwave intensification selective precipitation-ion liquid circulation to solve the problems such as high energy consumption, low selectivity of existing process, comprising: the gallium-containing vanadium residue is roasted under microwave, then low eutectic solvent is added to leaching, the obtained gallium-containing leaching solution is extracted with hydrophobic ionic liquid as extractant, the obtained gallium-loaded ionic liquid phase is used as electrolyte, and constant potential electrodeposition is carried out to obtain metallic gallium.The present application uses microwave to rapidly and selectively heat the gallium-containing mineral phase, which allows gallium to concentrate at the easily dissociated grain boundaries, then mild leaching is carried out by low eutectic solvent, and green recovery of gallium is achieved by ionic liquid electrodeposition, solving the problems of high temperature and high pressure, high pollution in traditional process.

A method for constructing antibiotic desalination nanofiltration membrane based on doctor-blade assisted interfacial polymerization relates to the field of antibiotic desalination separation membrane. The COFs separation membrane is composed of a hydrolyzed polymer membrane support layer and a continuous COFs selective membrane; the COFs separation membrane is prepared by uniformly coating a hydrophobic ionic liquid solution containing COFs A monomers on a hydrolyzed polymer membrane rich in COFs B monomer aqueous solution by using a doctor blade, so that the COFs A and COFs B monomers perform Schiff base reaction between the ionic liquid-water interface; the COFs separation membrane has a uniform pore size distribution; the COFs separation membrane has pore size adjustability, the COFs separation membrane can be prepared in a short time (less than or equal to 2 min), and has good crystallization performance. The separation membrane can realize rapid and efficient separation of different antibiotic molecules and salts.

The invention provides a solid electrolyte, a preparation method thereof and an all-solid-state lithium battery, the solid electrolyte comprises an inner core and a hydrophobic ion conductor coating coated on the surface of the inner core, the inner core comprises a sulfide inorganic solid electrolyte, and the hydrophobic ion conductor coating comprises a lithium salt I of perfluoroalkyl phosphate as shown in formula I; in the formula I, R1, R2 and R3 are respectively selected from one of hydrogen, and at least one of R1, R2 and R3 is selected from hydrogen; wherein m is an integer greater than or equal to 0, n is an integer greater than or equal to 5, and m + n is greater than 5. Based on the solid electrolyte provided by the invention, the air stability and cycle performance of the sulfide solid electrolyte are improved, and meanwhile, the solid electrolyte has relatively high ionic conductivity.

The present invention relates to a depot composition comprising calcium chloride inside microspheres. The depot composition according to the present invention can control excessive release of an active ingredient contained inside microspheres at the initial stage of depot injection by using calcium chloride as a cationic salt. In addition, the composition has excellent suspendability and a significantly small amount of residual solvent, and thus even when administered as an injection by a user, the effect of the active ingredient can be uniformly and continuously obtained. In addition, an improved medical therapy of semaglutide can be provided by adjusting the dose of semaglutide or tirzepatide by means of the depot formulation.

The invention discloses a process method for preparing high-purity rare earth metal through low-temperature electrolysis, and belongs to the technical field of rare earth metal metallurgy. The method comprises the following three steps: firstly, adopting a hydrophobic ionic liquid-supercritical CO2 composite medium, adding a responsive ligand, and triggering phase separation by adjusting temperature or pressure to realize high-selectivity separation and enrichment of target rare earth ions; secondly, the enriched rare earth salt solution is subjected to low-temperature plasma assisted fluorination conversion, and high-purity nano rare earth fluoride powder is obtained; and finally, dissolving the powder in a multi-element eutectic fluoride molten salt with the temperature of 580-650 DEG C, taking a composite cathode containing a hexagonal boron nitride interface release layer as a working electrode, applying programmed potential, coupling ultrasonic waves to perform electrolytic deposition, and rapidly cooling and stripping to obtain the high-purity rare earth metal. According to the method, low-temperature, efficient and green preparation of the rare earth metal is realized, the product purity is high, the energy consumption is obviously reduced, and the cathode can be recycled.

The present invention provides a method for preparing an electrolyte for an aqueous zinc battery with a wide temperature range. By utilizing the characteristic that the amphiphilic anions of zinc ion salts can cause the aqueous phase and the hydrophobic ionic liquid to change from phase separation to mutual solubility, a hydrophobic ionic liquid is introduced into the aqueous electrolyte, greatly improving the thermal stability, chemical stability, and electrochemical stability window of the aqueous electrolyte. The ionic liquid also achieves a highly reversible and long-life zinc deposition / stripping cycle through the tip effect of the cation inhibition zinc deposition process, and inhibits the dissolution of transition metal elements from the zinc battery positive electrode, thereby improving the cyclic stability of the positive electrode. The electrolyte prepared by the present invention can be removed by simple heating and / or vacuum treatment to cause the zinc ion salt and the ionic liquid to spontaneously phase separate, thereby achieving rapid recovery of high-value components in the electrolyte. Aqueous zinc batteries containing the above-mentioned electrolyte have the advantages of long service life and a wide operating temperature range. At the same time, the electrolyte components are easy to recycle, and have important application potential.

The invention is suitable for the technical field of elastomer materials, and provides an ionic conductive elastomer, a preparation method thereof and application of the ionic conductive elastomer in the field of underwater sensing. The ionic conductive elastomer P (EGPEA-co-AA)-IL takes a poly (acrylic acid-2-phenoxyethyl ester-co-acrylic acid) copolymer as a main body material; and hydrophobic ionic liquid 1-ethyl-3-methylimidazoline bis (trifluoromethylsulfonyl) imine is used as a conducting medium. The ionic conductive elastomer provided by the embodiment of the invention has ultrahigh underwater adhesive force, can immediately and spontaneously repair mechanical damage at room temperature, and is good in underwater stability, excellent in sensing performance, controllable in mechanical property and conductivity, simple in preparation method, and only needs one-step photo-initiated polymerization.