The invention relates to a large-area X-ray pulse detection device based on microchannel plate split joint. The large-area X-ray pulse detection device comprises an X-ray photoelectric cathode, a first insulating layer, a microchannel plate (MCP) input electrode press ring, a second insulating layer, an MCP input electrode, a first MCP layer, an intermediate electrode, a second MCP layer, a third insulating layer, an MCP output electrode, a fourth insulating layer, and an anode which are sequentially stacked up, wherein the first MCP layer and the second MCP layer are both large-area MCP detectors, and each MCP detector comprises a detector body, a split-joint framework and a processing circuit. The large-area X-ray pulse detection device resolves the technical problems that an existing MCP detector is adopted to detect the X-ray pulse, extremely long observation time is needed, and detection efficiency of the whole system is low, a detection method and a device which are high in detection efficiency are provided for an X-ray pulsar navigation system, photon measurement information with high time resolution and high time accuracy is provided for X-ray pulsar navigation, and guarantee is provided for high precision of navigation positioning.