The invention provides an anhydrous dyeing process and production line of high-end environment-friendly PU leather base cloth. The process includes the following step that greige cloth is sequentiallyand continuously subjected to cloth feeding, desizing, water washing, drying, rolling at room temperature, drying, color development and cropping. The process improves many problems caused by batch production of traditional leather base cloth with a dyeing cylinder. The anhydrous dyeing process and production line of high-end environment-friendly PU leather base cloth are ideal in design, each link is operated separately and independently, a production mode of an assembly line is formed, the production efficiency is greatly improved, and 50% labor can be saved. The water consumption is small,operation is performed just at room temperature, energy conservation and environment protection are achieved, energy consumption of dyeing is basically equal to zero, the dyeing rate is high, the prepared PU leather base cloth is high in strength, has no color difference, and the product quality is excellent. Meanwhile, the labor intensity of workers is reduced, operation is more convenient, flying nap, a dirty floor and dirty water can be effectively controlled, and the production environment in a workshop can be cleaner.