50results about How to "High industrial production value" patented technology

The invention discloses a synthetic method of steroidal gestagen and key medium I, II, III, IV in the drug chemical technological domain, which adopts 13 ethyl- 1,3,5(10),8(9)- estrange tetraenes-17-alcohol as raw material to synthesize deoxidation pregnancy and depending pregnancy.

The invention provides a honeycomb-shaped wet-method black-silicon texturing structure and a preparing method thereof and a black-silicon cell and a preparing method thereof, and relates to the technical field of black-silicon cell preparing. The preparing method of the honeycomb-shaped wet-method black-silicon texturing structure includes the steps that a diamond-wire polycrystalline silicon slice is subjected to hole digging operation through a wet-method black-silicon-tank hole digging device; products after hole digging operation is completed are subjected to hole expanding operation through a RENA chain-type device, NH3.H2O and H2O2 are added into alkaline wash liquid in an alkaline wash tank of the RENA chain-type device, and H2O2 is added into acid wash liquid of an acid wash tank.The ideal honeycomb-shaped wet-method black-silicon texturing structure with the excellent quality can be prepared, existing polycrystal production devices are fully used, and the device procurement/improvement costs are effectively reduced. The black-silicon cell prepared with the method is good in appearance performance and excellent in electric performance and has the large market popularization value.

The invention provides a method for synthesizing p-hydroxyacetophenone. The method comprises the following steps: firstly, 4'-chloroacetophenone is synthesized from chlorobenzene and acetic anhydrideas raw materials under catalysis of a Lewis acid catalyst, and the yield is 85%-91%; secondly, 4'-chloroacetophenone is hydrolyzed in an alkaline aqueous solution at high temperature and high pressure, p-hydroxyacetophenone is precipitated after acidification and cooling, and the yield is 90%-98%. The total yield of the two-step reaction is 77%-89%. Chlorobenzene is used as a starting material tosynthesize the p-hydroxyacetophenone, phenol used as the starting material in the traditional process is discarded, so that the defects that phenol is discharged with sewage and is not environmentallyfriendly as a result of incomplete reaction are avoided, and the method has high industrial production value.

The invention provides silicon-containing aromatic diamine and a preparation method thereof. Di-substituted silane and 4-vinylaniline or 3-aminostyrene are taken as raw materials and have a hydrosilation one-pot reaction under the action of a platinum catalyst, and di-substituted di(amino-phenethyl) silane is prepared. In the compound, two benzene rings containing amino are linked with the same silicon atom through two carbon atoms respectively, and the compound has excellent flexibility, flame retardancy and heat resistance. A synthetic process has the characteristics of easiness in obtaining of raw materials, simplicity in operation, mild conditions, high product yield, low cost, environmental protection and the like, and silicon-containing aromatic diamine has higher industrial production value.

The invention discloses a method for preparing a 7 Alpha-bromo steroid compound, comprising the following steps that: in the presence of a catalyst, a bromo reagent is in contact with a steroid compound having 7 Beta-oxhydryl to implement the stereoscopic selective bromation to the steroid compound having 7 Beta-oxhydryl, then the corresponding 7 Alpha-bromo steroid compound can be collected from reaction products. The method has advantages of simple operation, environment-friendly process, maximum 99 percent yield, low production costs and rather high industrialized production value.

The invention relates to the field of polypeptide synthesis and particularly relates to a method for reducing and/or removing a default peptide in solid phase synthesis of a polypeptide. The method adopts an all-protected peptide fragment comprising a default amino acid and an amino acid (C-N) in front of default amino acid in the solid phase synthesis of the polypeptide, the problems of default of the amino acid caused by incomplete removal of Fmoc and incomplete condensation reaction are solved at the same time, and the impurity of the default peptide is reduced to lower than the qualification threshold in the synthesis stage. For the specific performance, the Ala2 default impurity and the Thr5 default impurity in liraglutide are respectively reduced from more than 1% to the nesiritide amount and lower than 0.15%, and the Ser19 default peptide impurity in nesiritide is reduced to the undetectable amount.

The invention discloses a preparation method of an aluminum hydroxide surface modified expansible graphite flame retardant and a method for preparing flame-retardant polyurethane foam plastic by using the same, belongs to the field of flame-retardant materials, and particularly relates to a preparation method of a modified expansible graphite flame retardant and a method for preparing flame-retardant polyurethane foam plastic by using the modified expansible graphite flame retardant. The invention aims to solve the problems that the existing aluminum hydroxide flame retardants are more uniformly dispersed in polyurethane foam, and the mechanical property of the existing polyurethane foam plastic is poorer. According to the preparation method, sodium hydroxide, aluminum hydroxide and expandable graphite are used as raw materials, and a hydrothermal method is adopted. The method for preparing the flame-retardant polyurethane foam plastic comprises the following steps: 1, weighing; 2, mixing; and 3, curing. The method has the advantages that the limit oxygen index can be increased to 28.5%; the compression strength is improved to 0.162 MPa, and the percentage of closed area is improved. The methods are mainly used for preparing the aluminum hydroxide surface modified expandable graphite flame retardant and flame-retardant polyurethane foam plastic.

The invention belongs to the technical field of preparation of heterocyclic compounds, and specifically relates to a preparation method for amination synthesis of N-methylpiperidine from 1,5-pentanediol. The method comprises the following steps: with 1,5-pentanediol and monomethylamine as raw materials, carrying out an amination reaction in a tubular reactor filled with two upper-and-lower layersof a catalyst so as to obtain a crude product, and carrying out refining so as to obtain the N-methylpiperidine. The preparation method provided by the invention uses equipment with small size, is simple for industrial amplification, has relatively low cost and small technical investment, and can reach a product purity of 98.0% or above.

The invention provides a multistage sewage treatment device and a sewage purification system and relates to the field of sewage purification. The multistage sewage treatment device comprises a device body, an oxygen supply device, a dissolved oxygen measurement device and a control system, wherein a sewage inlet and a purified water outlet is arranged on the device body; the device body further includes a settling section, a swirling oil-gas separation section, a large particulate matter filtration section, and a fine-particle filtration section which are sequentially arranged from top to bottom; the sewage inlet is arranged on the settling section and the purified water outlet is arranged on the fine-particle filtration section; the oxygen supply device is connected to the swirling oil-gas separation section through an oxygen supply pipe; the dissolved oxygen measurement device comprises a dissolved oxygen electrode which is arranged in the swirling oil-gas separation section and a dissolved oxygen meter which is electrically connected with the dissolved oxygen electrode and is arranged outside the device body; the dissolved oxygen meter and the oxygen supply device are electrically connected to the control system. The multi-stage sewage treatment device has the advantages that usage is simple, automation degree is high, sewage treatment effect is good, industrial production value is greater.

The invention provides a chiral purification method of a compound C. The compound C is a crude product (S,S)-8-benzyl-2,8-diazabicyclo[4.3.0]nonane with chiral purity ee of 90%-98%. The chiral purification method comprises the following steps: forming haloid salt from the compound C, and further crystallizing and purifying the compound C haloid salt to obtain a high-purity refined product haloid;carrying out alkali treatment and toluene extraction on the refined high-purity haloid acid salt to obtain the high-chiral-purity (S,S)-8-benzyl-2,8-diazabicyclo[4.3.0]nonane. According to the process, a relatively expensive optical resolving agent is prevented from being used for secondary resolution, and the whole process is simple to operate due to the fact that the refined product is insolublein water and an organic solvent is easy to extract; besides, the refining yield is greater than 90%, which is far higher than the yield of secondary resolution of the resolving agent, so that the method is easy to amplify and suitable for industrial production.

The invention discloses a method for preparing 2,6-dichloro-alpha-(4-chlorphenyl)-4-nitro phenylacetonitrile by condensation of 3,5-dichloro-4-fluronitrobenzene and p-chloro-phenylacetonitrile, wherein the used raw material 3,5-dichloro-4-fluronitrobenzene is derived from distillation residue of a production process for preparing 2,4-dichloro-3-fluronitrobenzene by nitrifying 2,6-dichlor fluorbenzene; and the residue contains 83.5-88.2% of 3,5-dichloro-4-fluronitrobenzene and 9.0-13.3% of 2,4-dichloro-3-fluronitrobenzene, and 3,5-dichloro-4-fluronitrobenzene with content more than 98% can be obtained by selective solvent extraction and once or twice recrystallization and is subjected to condensation with p-chloro-phenylacetonitrile to obtain 2,6-dichloro-alpha-(4-chlorphenyl)-4-nitro phenylacetonitrile with yield above 98%. Compared with the existing method for preparing 2,6-dichloro-alpha-(4-chlorphenyl)-4-nitro phenylacetonitrile, the method has the characteristics of inexpensive and easily available raw materials, sufficient utilization of resources, mild conditions, high yield, low wastewater discharge and the like, and is more suitable for industrial production.

The invention provides sphingosine monad with the preservation number of CGMCC No.12394, a method for culturing carotenoid production strain, application of the carotenoid production strain to production of carotenoid, and application to industrial production of astaxanthin. According to the sphingosine monad generating nostoxanthin, the content of nostoxanthin can reach 3.98+/-0.5 mg/g, accounting for at least 90% of total pigment. Bred colorless phytoene producing strain SP-Phy, red lycopene producing strain SP-Lyc and yellow zeaxanthine producing strain SP-Zea are subjected to at least five generations of continuous passage, the yield of phytoene, lycopene and zeaxanthine is stable, and the content of phytoene, the content of lycopene and the content of zeaxanthine reach 3.7+/-0.5 mg/g, 3.9+/-0.5 mg/g and 4.0+/-0.5 mg/g respectively, accounting for at least 90% of total pigment. By introducing ketonized enzyme genes to the bred zeaxanthine producing strain SP-Zea, the zeaxanthine producing strain SP-Zea can be transformed into astaxanthin producing strain SPZ-AST, and the content of astaxanthin reaches 4.1+/-0.5 mg/g, accounting for at least 90% of total pigment.