220results about How to "Three wastes less pollution" patented technology

The invention provides a 3-methylamine tetrahydrofuran preparation method, wherein 1,4-butenediol is adopted as a raw material and is subjected to cyclization dehydration under the catalysis effect of a solid acid to produce 2,5-dihydrofuran, the 2,5-dihydrofuran reacts with water gas under the catalysis effect of cobalt acetate to produce 3-tetrahydrofuran formaldehyde, and the 3-tetrahydrofuran formaldehyde, ammonia gas and hydrogen gas are subjected to a hydrogenation reaction under the catalysis effect of 5% Pd/C to prepare the target product3-methylamine tetrahydrofuran, wherein the purity is 98.12%, and the total yield is 74.16%. According to the present invention, the preparation method has advantages of cheap and easily available raw materials, less steps, simple operation, high product purity, high yield, less three-waste pollution and production cost reducing, and is suitable for industrial production.

The invention discloses a preparation method of solid phase peptide synthesis triptorelin, which includes the following steps: with Rink Amide AM resins or Rink Amide MBHA resins as starting materials, amino acids with protective groups are sequentially connected according to solid phase synthesis, so as to obtain protective decapeptide resins, and meanwhile crude products are obtained by sequentially removing Fmoc-protective groups and synchronously removing side-chain protective groups and cutting peptides, and triptorelin elaborate products are prepared after the crude products are separated and purified by C18 (or C8 ) column and freeze-dried. The preparation method is stable in technology, convenient in raw and auxiliary material sources, short in production cycle, high in yield, stable in quality, low in production cost and high in transpeptidase yield. Besides, as the preparation method avoids using poisonous reagents, such as hydrogen fluoride, and the like, the pollution of three wastes is low, purification yield is over 25 percent and each step of transpeptidase yield is above 98 percent; the yield after cutting peptides is 78.8 percent and the total yield is 25.4 percent.

The invention relates to ultrafine fiber with high color fastness and a manufacturing method thereof. The method comprises the steps of adding 3-40% coloring agent into a polymer powder to make into colored stock particles; adding the colored stock particles into spinning polymer polyester and/or polyamide in a ratio of 0.2-15%, and mixing; melt extruding the spinning polymer with a conjugate spinning machine, and coiling to obtain colored POY composite fiber; stretching and false-twist texturing to obtain colored fiber with high color fastness; and splitting with a basic hydrolysis method to obtain colored ultrafine fiber with high color fastness. The colored ultrafine fiber with high color fastness has excellent handfeel and color fastness to washing and light, and contains mass-colored dyeing components, so as to dispense with dyeing after being made into a textile. The colored ultrafine fiber has the advantages of simple process, low cost, low pollution, small product color difference, good color fastness, low fading liability, wide color spectra, and vivid and bright color.

The invention discloses a method for preparing 2-ethyl hexanoic acid by catalytically oxidizing 2-ethylhexanal by molybdovanadophosphoric acid, and relates to a method for preparing a chemical preparation. The method comprises the following steps: weighing molybdovanadophosphoric acid and dissolving the molybdovanadophosphoric acid in distilled water at first and then in hydrochloric acid to prepare a catalyst solution; adding 2-ethylhexanal and the prepared catalyst in an ordinary-pressure reaction device, slowly heating and stirring the mixture, regulating oxygen flux, and starting to introduce oxygen when the temperature rises to the reaction temperature; after the reaction is ended, separating out the aqueous phase solution on the lower layer to obtain organic phase matter on the upper layer; and depressurizing and distilling the organic phase matter to obtain colorless transparent and pungent oily liquid, 2-ethyl hexanoic acid. By changing the ratio of molybdenum to vanadium of the catalyst and optimizing the reaction condition, the conversion rate of the 2-ethylhexanal reaches above 99%, and the selection and yield of the 2-ethyl hexanoic acid reach above 98% respectively.

The invention discloses a 3-cyclohexyl-1,1-dimethylurea compound as well as a preparation method and application thereof. The 3-cyclohexyl-1,1-dimethylurea compound is used for preparing an antischizophrenic drug cariprazine. Compared with the prior art and report literatures, the preparation method of the 3-cyclohexyl-1,1-dimethylurea compound has the remarkable advantages of being free of removal of protecting groups such as Boc group, high in atom economy, low in cost and easy in getting of raw materials, mild in reaction condition, stable in yield, simple and convenient to operate, controllable in product quality, high in product purity, less in three waste pollution and easy to produce industrially. The structure formula of the 3-cyclohexyl-1,1-dimethylurea compound is as shown in (I) in the specification.

The invention discloses high-temperature resistant polyimide wire enamel and a preparation method thereof. The wire enamel comprises the following components in percent by weight based on total mass of enamel liquor: 50-80 percent of polyimide acid solution with solid content of 30 percent and 0-40 percent of chain-extended bismaleimide prepolymer solution with solid content of 30 percent. The preparation method of the high-temperature resistant polyimide wire enamel comprises the steps of mixing the polyimide acid solution and the chain-extended bismaleimide prepolymer solution according to proportions, adding an organic solvent to adjust the solid content and viscosity of the enamel liquor, and stirring to uniformly mix, thus obtaining claret-red transparent viscose polyimide wire enamel. The wire enamel disclosed by the invention is good in storage stability, resistant to high temperature, uniform in enamel film, good in flexibility, simple and easy to operate in an enamel and wire preparation process, high in raw material utilization rate, little in three-waste pollution and easy to realize industrialization; the soft breakdown voltage and the breakdown voltage of the wire enamel are remarkably higher than 240-level polyimide enamelled round copper wire standard in China respectively. The high-temperature resistant polyimide wire enamel can be used for insulation of a high-load, high-power and refrigerant-resistant motor and has broad market prospects.

The invention discloses a method for preparing oxytocin through solid phase polypeptide synthesis, comprising following steps: taking Rink Amide resin (comprising Rink Amide MBHA resin, Rink Amide Am resin) as raw material, taking amino acid protected by Fmoc, TBTU or HBTU/ HOBt as condensing agent, making up amino acid in sequence; adding peptide cutting agent for peptide cutting, adding for precipitation and getting reduced coarse product; adding basic matter, feeding air for oxidation or oxiding with H2O2 with pH being 7.5- 10.0, getting oxidized coarse product; separating and purifying by using C18 or C 8 column and getting final product. The method is characterized by low production cost, simple process, little pollution, high production rate and convenience for industrial production.

The invention relates to a method for synthesizing dianhydride monomer, especially a method for synthesizing aryl diether dianhydride by condensation, hydrolysis, acidification, and dehydration. In the invention, catalyst is added in the process of condensation for improving the yield of product; the solid content is 10-20%, reaction temperature is 7-100C., and reaction time is 15-48 hours; and the solvent consumption is reduced for reducing the impurity in condensed product. And diether tetracid in the diether dianhydride treated by dehydration is removed by dehydration in toluene or acetic acid and acetic anhydride and high temperature dehydration in vacuum oven sequentially, and the targeted product processed by said method has melting range less than 1C. and high purity.

The preparation process of solid phase polypeptide synthesized eptifibatide includes the following steps: (1) connecting amino acids one by one with Rink Amide resin, Rink Amide MBHA resin or Rink Amide AM resin as initial material, and Fmoc protected amino aids as monomer, with the last peptide chain being S-benzyl mercapto propionic acid Map(SBzl); (2) adding peptide cutting agent (TFA/HBr/HAc/TIS/EDT) to cut peptide; (3) precipitating and collecting coarse reductant eptifibatide product in ether solvent; (4) dissolving coarse reductant eptifibatide product in water, regulating pH value with ammonia water to 7.5-10.0, introducing air for oxidation, and collecting coarse eptifibatide product; and (5) separating and purifying the coarse product in C18 column to obtain the target product. The present invention has high yield, and is suitable for industrial production.

The invention discloses a preparation method of solid phase peptide synthesis atosiban which includes the following steps: taking Rink Amide resins, Rink Amide MBHA resins or Rink Amide AM resins as starting materials and taking Fmoc amino acids as monomers, amino acids are grafted one by one and mercaptopropionic acids (Map(SX)) are protected by the last peptide chain; after protected nonapeptide resins are obtained, the acellular side-chain protective groups and cutting peptides are synchronized; then cutting peptides is carried out, and reduced crude atosiban is collected; the pH value is adjusted to 7.5 to 10.0, and oxidized crude atosiban is collected; target products are obtained by the separation and purification by preparative HPLC(C18 or C8 column). The preparation method is convenient in material source, simplifies technology and reduces cost; and the preparation method is low in the pollution of three wastes and is high in yield, and the preparation method is convenient for being industrialized and has good industrialization prospect.

The invention relates to a polypeptide synthesis method for octreotide acetate. The method comprises the following steps of: taking chloromethyl resin as a starting raw material, preparing a cesium salt from Boc-Thr(tBu)-OH, sequentially connecting amino acids with protecting groups according to a solid-phase synthesis method so as to obtain protected octapeptide resin, meanwhile, removing Boc protecting groups by sequentially using HCl/isopropyl alcohol, carrying out peptide connecting reaction in a manner of taking DIC and HOBT as condensing agents, carrying out reduction by using palladium carbon/hydrogen gas, meanwhile, cutting off peptide chains so as to obtain reduced octreotide, introducing air at the Ph of 7.8-9 so as to cyclize disulfide linkages, then, obtaining a crude octreotide product, and carrying out separation and purification through a C18 column, thereby preparing a fine octreotide acetate product. The method disclosed by the invention has the advantages that threoninol and Fmoc-threoninol are not adopted, the production cost is very low, the method has large-scale production capacity, the process is stable, the raw and auxiliary materials are convenient to obtain, the production cycle is short, the yield of connected peptide is high, the quality is stable, the use of highly-toxic reagents, such as hydrogen fluoride, trifluoroacetic acid and the like, is avoided, and the pollution caused by waste gas, waste water and waste residues is little.

The invention relates to a method for synthesizing a dianhydride monomer, in particular to a method for synthesizing an aromatic HQEDA monomer. The method adopts a 3(4) substituted phthalimide to prepare HQEDA and provides novel middle steps for preparing the HQEDA. The method comprises the following steps: preparing a 3 (4) substituted-N-alkyl (aryl) phthalimide from the 3(4) substituted phthalimide through Gabriel reaction principle or by adding a salifying agent and halocarbon into an apolar aprotic solvent to react; and using the prepared 3 (4) substituted-N-alkyl (aryl) phthalimide to prepare bis imide and the bis ether anhydride. The method has the advantages that raw materials are easily available, preparation method is simple and easy to operate, and the purity and yield of the prepared 3 (4) substituted-N-alkyl (aryl) phthalimide are obviously higher than that of the prior method.

This invention provides a new technology of producing sodium glutamate, including the following steps: first, nitrogen source and alkali sodium are mixed and added into broth to get a broth containing sodium glutamate crude product and its pH is 6.8 to 7.2. Then the broth is filtered through the membrane and followed by centrifugation to get a centrifuged broth. The broth is isolated and purified through the ion exchange resin for, and the effluent is collected and condensed to get glutamate sodium after crystallization.

The invention relates to an industrial production method for ethoxy quinolone. The industrial production method comprises the following steps: adding p-phenetidine, a diluent and a home-made chelate catalyst serving as raw materials into a reaction kettle; heating to 125-165 DEG C; dropwise adding acetone to perform a synthetic reaction; preserving heat for half an hour after finishing dropwise adding of the acetone; recovering the diluent by distilling; fractionating under a reduced pressure to obtain the ethoxy quinolone. The ethoxy quinolone is over 98 percent in purity, is less than 0.5 percent in raw material residues, and is over 90 percent in total yield.

The invention relates to hyperbranched polyaminoester capable of emitting multicolor fluorescence and a preparation method thereof. Citric acid and N-methyldiethanolamine (or malic acid and triethanolamine) are used as raw materials to be synthesized into the hyperbranched polyaminoester by a simple controllable polycondensation method. The synthesized hyperbranched polyaminoester does not containbenzene rings and only contains ester groups; the biodegradation is easy; the hyperbranched polyaminoester can emit the multicolor fluorescence. The synthesized hyperbranched polyaminoester can emitbright fluorescence of different colors (including red, yellow, blue and the like) under the irradiation of different wavelength ultraviolet light. The method has the characteristics that the synthesis process is simple and convenient; the process is controllable; the environment-friendly effect is achieved and the like; the three-waste pollution is little; the product stability is high; the toxicity is low; the biodegradability is high; the fluorescence intensity is high; the colors are rich; the application range is wide, and the like.

The present invention relates to a production method of super fine fibre, in particular it relates to a production method of colored functional super fine fibre. Said production method includes the following several steps: directly mixing super fine fibre raw material with coloring material, adjuvant and functional additive according to a certain mixing ratio to obtain colored anti-bacterial mother materi, melting said mother material at high temperature, extruding said molten mother material by using twin-screw extruder and making basic hydrolysis so as to obtain the invented product.

The invention discloses a method for synthesizing 3,5-diamido benzoic acid by industrial continuous hydrogenation. The method comprises the following steps: by taking m-dinitrobenzoic acid and hydrogen as raw materials and water as a reaction solvent, adding water and a catalyst in a reduction kettle, in addition, respectively adding the raw material, namely m-dinitrobenzoic acid and hydrogen for reduction reaction; carrying out further reaction on a reaction liquid in second and third reduction kettles until the conversion rate of the raw materials reaches 100%; and then crystallizing the reaction liquid so as to obtain the product 3,5-diamido benzoic acid. In the method, three reduction kettles which are successively connected are adopted so as to complete the reduction reaction, the contact time of the raw materials is long, the conversion rate of the raw materials can reach 100%, the appearance of the obtained product is of grey white powder, the chromatograph purity of the product is above 99%, the content of the product is above 95%, and the yield of the product is above 97%.

The invention relates to composite additive for oxidizing roasting of vanadium ores and a method for roasting the vanadium ores. The additive is prepared by mixing four powder materials which are crushed into 20 to 80 meshes in percentage by mass: 30 to 95 percent of calcium carbonate powder, 0 to 50 percent of magnesium carbonate powder, 0 to 20 percent of calcium oxide powder and 0 to 50 percent of sodium sulfate powder, wherein the addition of the latter three powder materials is not 0 at the same time. The additive has low manufacturing cost, is well adaptive to various vanadium-containing ores, has the roasting conversion rate which reaches more than 85 percent and is more than 20 percent higher than that of the prior additive, and solves the technical problems of single composition, low roasting conversion rate, environmental pollution, high cost and the like in the prior additive for roasting the vanadium ores. Because the additive is well adaptive to various vanadium-containing ores, the additive can be taken as the roasting additive of various vanadium ores.