54results about How to "Prevention and treatment of Alzheimer's disease" patented technology

The invention relates to a medication composition and a process for preparation the invention which is for improving cerebral cognitive function disorder, preventing and curing senile dementia. The medication composition of the invention is composed of curcuma, ginkgo leaf and thinleaf milkwort root-bark which are prepared by the techniques of weighting, drying, crashing, marinating, poaching, ethanol extracting, condensing, merging and the like. The medication composition of the invention has the effects of opening the key to the mind, refreshing the brain, nourishing heart, invigorating the circulation of blood, recuperating yin and yang, and resisting senescence, which is capable of improving study memorizing ability, and overcoming cerebral cognitive function disorder, thereby preventing and curing senile dementia.

Disclosed is a compound tomatine preparation for female and its preparing process, wherein the preparation comprises tomatine, soybean isoflavones, vitamin E, anti-oxidant, capsule stabilizing agent and balancing deflocculating agent. The preparation can be made into the dosage forms of soft capsules, tablets or oral liquids.

A nano coffee classified into two categories, the first category being nano powdered coffee prepared by disintegrating the coffee coarse powder through air stream disintegration and ball grinding disintegration, and obtaining 50-500 nm particles, the second category being nano slow release coffee prepared by extracting coffee essence through abstraction, water extraction or percolation filtration extractive technique, wherein the slow release 50-500 nm particle coffee is prepared through nano packing process.

The invention discloses asparagus tea. Raw materials of the asparagus tea by weight are 100 parts of asparagus, 3 parts of winter cherry leaves, 2 parts of fructus amomi, 5 parts of pearl white, 2 parts of tender willow leaves, 1 part of kaffir lily leaves, 4 parts of cucumber leaves, 1 part of sesame leaves, 2 parts of strawberry leaves, 1 part of cumin, 2 parts of liquorice, 1 part of azedarach, 10 parts of black beans, 10 parts of soybean shells, 3 parts of jackfruit peel with inner layer white flesh removed and 5 parts of tuna eyeballs. An A extracting solution is obtained through the asparagus, the winter cherry leaves and the fructus amomi. A B extracting solution is obtained through the pearl white. A C extracting solution is obtained through the black beans, soybean shells, the tender willow leaves, the kaffir lily leaves, the cucumber leaves, the sesame leaves, the strawberry leaves, the cumin, the liquorice, the azedarach and the jackfruit peel. A D extracting solution is obtained through the tuna eyeballs. The extracting solutions A, B, C and D are mixed and concentrated, spray drying is carried out, and an asparagus tea finished product with water content of 2% is obtained. The asparagus tea is good in mouthfeel and rich in nutrition.

The invention discloses a preparation method for the oral liquid of Rhizoma Gastrodiae. According to the method, enzymatic hydrolysis, ultrasonic treatment, flocculation, centrifugation and membrane separation technologies are adopted to remove impurities, improve clarity, and efficiently extract the functional components of Rhizoma Gastrodiae; and the method of the invention avoids concentrationand drying, so the functional components of Rhizoma Gastrodiae are prevented from oxidation and decomposition, and the content of gastrodin is increased by 25-37% compared to the prior art. The oral liquid of Rhizoma Gastrodiae in the invention is rich in various functional components which produce synergistic effect, so the oral liquid of Rhizoma Gastrodiae is capable of developing intelligence,tonifying the brain, preventing and treating dementia, improving sleep, growth and development, enhancing immunity, helping the improvement of memory functions, assisting in blood pressure lowering and resisting vertigo, epilepsy, convulsion and rheumatism and has other health care effects; moreover, the oral liquid of Rhizoma Gastrodiae is high in yield and low in energy consumption and production cost; experimental results prove that the oral liquid of Rhizoma Gastrodiae is safe and effective and has no toxic and side effect; and the preparation method is simple in preparation process and suitable for industrial production and marketing application.

The invention relates to qi-blood tonifying health tea capable of reducing hyperlipidemia, hypertension and hyperglycemia and a preparation method thereof. The qi-blood tonifying health tea capable of reducing the hyperlipidemia, the hypertension and the hyperglycemia is prepared by decocting ginseng flowers, astragalus membranaceus, Chinese yams, lucid ganoderma, cynomorium songaricum, rhizoma curculiginis, herba cistanche, cinnamon, raw hawthorns, longan pulp, ginkgo leaves, bitter citrus immature flowers, wild chrysanthemum flower, mulberries, kudzuvine roots, sealwort and like, adding auxiliary materials and performing spray drying. The Qi-blood tonifying health tea capable of reducing the hyperlipidemia, the hypertension and the hyperglycemia and the preparation method thereof have the advantages that the health tea is developed and improved by conforming to a traditional Chinese medicine decoction decocting method and combining a modern pharmaceutical technology according to the traditional Chinese medicine theory; original taste and flavor of an original traditional Chinese medicine beverage is maintained, the quality and curative effect can be further improved, and qi-blood tonifying and basis consolidating are achieved; the hyperlipidemia, the hypertension and the hyperglycemia are reduced, and a patient can take more conveniently.

The invention discloses an application of a peanut coat active component and a composition comprising the peanut coat active component. The peanut coat active component can be used for preparing foods and medicines for preventing and treating neurodegenerative diseases. The invention also provides a composition comprising the peanut coat active component and Omega-3 series unsaturated fatty acid. The invention provides a new application of the peanut coat active component, thus offering a new thinking for preparing foods and medicines for preventing and treating neurodegenerative diseases like Alzheimer's disease. In addition, the composition also contains omega-3 series unsaturated fatty acid besides the peanut coat active component, thus better improving memory function.

The invention discloses cyclocarya paliurus tea bag. The cyclocarya paliurus tea bag is characterized by comprising raw materials in percentage by mass as follows: 80% of cyclocarya paliurus tender leaves and 20% of bitter melon slices, ginseng slices, fructus lycii and pearl powder. A preparation technology of the cyclocarya paliurus tea bag comprises steps as follows: (1), the materials are selected and weighed as required; (2), the materials are washed; (3), the materials are dried; (4), the materials are rolled; (5), the materials are subjected to grinding; (6), the materials are subjected to secondary drying; (7), the materials are subjected to high-temperature sterilization; (8), the materials are inspected and bagged. The cyclocarya paliurus tea bag and the preparation technology have the characteristics as follows: the cyclocarya paliurus tea bag in the scheme can reduce blood glucose, reduce serum glutamic pyruvic transaminase and promote repair of liver injury, and has functions of benefiting qi, nourishing blood, enriching yin, nourishing the kidney, strengthening the spleen, nourishing the stomach, delaying senescence, maintaining beauty and the like; arachnoid cyanotis root is added, is rich in beta-ecdysone, and has remarkable functions of reducing blood glucose, strengthening muscles, preventing and treating senile dementia and the like.

The invention relates to a traditional Chinese medicine preparation for treating senile dementia, encephalatrophy and dysgnosia. The traditional Chinese medicine preparation is prepared from the following substances in parts by weight: pilos antler, saffron crocus, astragalus membranaceus, herba cistanche, earthworms, turtle paste, hirudo, golden cypress, semen cuscutae, morinda officinalis, salvia miltiorrhiza, ligusticum wallichii, tail of Chinese angelica root, peach kernels, radix paeoniae rubra, dipsacaceae, radix achyranthis bidentatae, rhodiola rosea, polygala tenuifolia, radix angelicae, notoginseng, safflower carthamus, caulis spatholobi, rhizoma drynariae, epimedium and rehmannia glutinosa. According to the traditional Chinese medicine preparation, the cognition impairment can be improved, the cerebral atrophy can be delayed, the memory can be increased, and an obvious effect of preventing and treating the senile dementia is achieved.

The invention discloses a drug structure as shown in the general formula (1), wherein, R1-R5 is independently selected from H, OH, halogen, NO2 or OR, R represents C1-C6 alkyl. The in vitro experiments of pharmacodynamics show that the compound can protect neurons, control Alzheimer disease, and the compound has obvious inhibiting effects to parkinsonism and other neurodegenerative diseases.

The invention relates to extracts of vietnamese sophora root and application thereof and in particular relates to a petroleum ether extract, an ethanol extract and an ethyl acetate extract of vietnamese sophora root. Through experiments, the petroleum ether extract, the ethanol extract and the ethyl acetate extract of vietnamese sophora root can be used for preventing and treating the Alzheimer's disease and have better effects than the prior art.

The invention discloses a health egg which is oxidation resistant, preventing and curing the senile dementia, born by poultry nursed with feed stuff added with curcuma longa; adding curcuma longa of 5-1000mg per basic feed stuff for poultry or curcuma longa slag of 5-300g, with the nursing time for at least 8 days, and the curcuma longa can be added in the long run. The invention makes the function of curcuma longa and polarity egg be combined together, which makes the action of oxidation resistance and prevention and cure of the senile dementia stronger. The invention employs biological transformation technique, employs poultry laying egg as carrier, to transform the effect component in the curcuma longa into eggs through the biological enrichment function of poultry, and to realize purpose of being oxidation resistant, and preventing and curing the senile dementia.

The invention belongs to the technical field of food processing, and particularly relates to health-care coarse food grain cakes for old people and a making method of the health-care coarse food graincakes. The health-care coarse food grain cakes comprise the following raw materials of a purslane herb extract, a mulberry leaf extract, endive polysaccharide, mannitol, sugar-free condensed milk, acoarse food grain material, citric acid, iron yams, water and the like. In accordance with problems that high-fiber low-calorie coarse food grain cakes are single in nutrients and difficult to digest,the purslane herb extract, the mulberry leaf extract and the endive polysaccharide are added as efficacy components, so that the obtained coarse food grain cakes have the prevention and treatment effects on chronic diseases of diabetes, cardiovascular diseases, constipation, abdominal distension, high blood pressure, high blood lipid and the like for old people. Secondly, the mannitol is used forreplacing cane sugar, so that load of sugar eaten by the old people cannot be increased, the health-care coarse food grain cakes have unique pleasure flavor, the edibility of the coarse food grain cakes is improved, and the coarse food grain cakes have effects of being health-care and health-preserving, reducing the attack rate of chronic diseases of old people after being eaten for a long term,and have broad market prospects.

The invention relates to a traditional Chinese medicine composition and a drug containing the same. The traditional Chinese medicine composition is prepared from traditional Chinese medicine components of radix ginseng, lucid ganoderma, radix astragali, radix ophiopogonis, herba dendrobii, radix polygalae, rhizoma acori tatarinowii, pumice, rhizoma gastrodiae, radix angelicae sinensis, leech, rhizoma ligustici, dragon bone, tortoise plastron, stir-fried spiny jujube, rhizoma polygonati, chinese wolfberry fruit, herba epimedii, sliced processed aconite and placenta hominis. The traditional Chinese medicine composition selects and uses natural Chinese herbal medicines as raw materials, has a good health function on a human body, is small in side effect, and achieves the purposes of preventing senile dementia and warding off diseases to build bodies.

The invention discloses a pharmaceutical composition and a preparation method, a preparation and application thereof. The pharmaceutical composition consists of the following materials in parts by weight: 30-40 parts of resina draconis, 20-30 parts of folium ginkgo, 5-10 parts of rhizoma gastrodiae and 5-10 parts of rhodobryum roseum limp. The preparation method comprises the following steps: crushing and sieving folium ginkgo and rhodobryum roseum limp, and extracting to obtain a folium ginkgo and rhodobryum roseum limp extract; crushing and sieving resina draconis and rhizoma gastrodiae for later use; merging the folium ginkgo and rhodobryum roseum limp extract with resina draconis and rhizoma gastrodiae, uniformly mixing, and conducting superfine grinding to obtain the target object. The preparation is powder, tablets, capsules, particles, drop pills or honeyed pills, prepared by adding pharmaceutically acceptable auxiliary materials into the pharmaceutical composition. The pharmaceutical composition is applied to preparation of medicines for treating AD. The pharmaceutical composition has the functions of invigorating qi and blood, dispersing blood stasis and relieving depression, restoring consciousness and easing mental stress, improving sleep and preventing and curing AD, has the characteristics of good effect, less toxic or side effects, simple and convenient preparation method and the like, and is suitable for clinical popularization and application.

The invention discloses a chewing gum with black gingko kernel. The chewing gum is mainly prepared from black gingko kernel; L-arabinose, xylitol and sorbierite are used for replacing granulated sugar and granulated sugar; black gingko kernel, L-arabinose, xylitol, sorbierite and auxiliary materials are mixed with chewing gum base according to a certain weight ratio, wherein the auxiliary materials refer to tea polyphenol, sodium erythorbate, citric acid and the like. The chewing gum with black gingko kernel is fashionable snack food, is good for health, has health-care effects and is suitable for more consumer groups, especially for people with cardiovascular and cerebrovascular diseases, hypertension, hyperlipidemia, hyperglycemia, obesity and the like; therefore, the chewing gum with black gingko kernel has good market prospect.

A nano chocolate classified into two categories, the first category being nano powdered chocolate prepared by disintegrating the coarse cocoa bean powder through air stream disintegration and ball grinding disintegration, and obtaining 50-500 nm particles, the second category being nano slow release chocolate prepared by extracting chocolate raw material essence through abstraction, water extraction or percolation filtration extractive technique, wherein the slow release 50-500 nm particle chocolate block is prepared through nano packing process.

The invention discloses gastrodia elata health-care yoghourt. The yoghourt is prepared from the following raw material components: fresh milk, gastrodia elata polysaccharide enzymatic hydrolysate, sugar and a yoghourt fermenting agent, wherein the mass ratio of the adopted fresh milk, the gastrodia elata polysaccharide enzymatic hydrolysate, the sugar to the yoghourt fermenting agent is 1:(0.05-0.1):(0.05-0.1):(0.02-0.05). The invention further discloses a preparation method of the gastrodia elata health-care yoghourt. According to the method, the enzymatic hydrolysate with the gastrodia elatapolysaccharide yield of 5.03% or above is obtained by optimizing enzyme reaction time, pH value and enzyme dosage, and then the content of soluble polysaccharide is increased. In coordination with the sugar and fermented yoghourt, the method can acquire the solidified gastrodia elata yoghourt which is fine and smooth in tissue, fine and uniform in curd, free of bubbles, good in taste and rich innutrients.

The invention discloses application of a fructus hippophae water-soluble extract for preparing a preparation capable of inhibiting the phosphorylation of a Tau protein. The fructus hippophae water-soluble extract accounts for 20-45 wt% of the preparation capable of inhibiting the phosphorylation of the Tau protein. Compared with the prior art, the invention has the following beneficial effects that (1) the phosphorylation of the Tau protein is inhibited so as to prevent and treat the Alzheimer's Disease, a choline inhibitor which is commonly used at present is not adopted, and therefore, no side effects are caused; and (2) through a synergistic effect of all substances, the Alzheimer's Disease is prevented and treated, each medicine independently performs an effect by aiming at the etiology and the pathogenesis of the Alzheimer's Disease and mutually coordinates, a prevention and treatment principle of strengthening the body resistance to eliminate pathogenic factors and addressing both symptoms and root causes is followed, all medicines are combined to jointly perform the efficacy of warming the kidney, strengthening the spleen, invigorating qi, consolidating superficies, and promoting blood circulation to remove meridian obstruction, the fructus hippophae water-soluble extract has an excellent prevention and treatment effect on the Alzheimer's Disease, and a cure rate is high.

The invention discloses a healthcare traditional Chinese medicine for quinquagenarian. The medicine comprises the following components in percentage by weight: 28-34% of unprepared rehmannia root, 3.5-4.0% of ginseng, 3.5-4.0% of radix scrophulariae, 3.5-4.0% of salvia, 3.5-4.0% of poria with hostwood, 3.5-4.0% of platycodon grandiflorum, 3.5-4.0% of polygala tenuifolia, 7.4-8.0% of jujube kernel, 7.4-8.0% of semen boitae, 7.4-8.0% of Asparagus cochinchinensis, 7.4-8.0% of radix ophiopogonis, 7.4-8.0% of angelica sinensis and 7.4-8.0% of schisandra chinensis, cinnabar is adopted as a medicine coating, and the components together with juncus effusus are boiled in water. The healthcare traditional Chinese medicine for quinquagenarian has the effects of nourishing yin and clearing heat and tonifying heart to calm nerve, and is a good product for quinquagenarian healthcare.

The invention discloses salad oil capable of promoting mentality and invigorating brain for special dietary use and a preparation method thereof, and belongs to the technical field of salad oil. The salad oil capable of promoting mentality and invigorating brain for special dietary use disclosed by the invention is prepared from the following components in parts by weight: 80-93 parts of basic oiland fat, 15-21 parts of oil and fat for special dietary use, 5-13 parts of an active substance and 5-11 parts of a Chinese herbal medicine substance capable of promoting mentality and invigorating brain. The salad oil capable of promoting mentality and invigorating brain for special dietary use disclosed by the invention is natural in selected materials, rich in flavor, reddish brown in color, light in taste and balanced in nutrition, can help treat, prevent and delay the deterioration of nerve cell function and brain atrophy in the elderly, and can prevent and delay senile dementia and promote brain development in children, promote mentality and invigorate brain.

An oral or injection preparation of the medium and long-chain fat emulsion of Camelina sativa oil relates to a medical care and nutritional fat emulsion product which contains Camelina sativa oil and is prepared according to prescription. The weight proportion of the invention is: 0.1 percent to 20 percent of Camelina sativa oil which is taken as medicine, 0 percent to 20 percent of MCT which is taken as rapid energy-provision agent, 0 percent and 15 percent of lecithin which is taken as emulsifier, 0 percent and 30 percent of refined oil which is taken as oil solvent and 0.15 to 0.25 percent of glycerin which is taken as isoosmotic adjustment agent, and water for injection is added till the total amount reaches 1000g; wherein, the final osmotic pressure of glycerin which is taken as isoosmotic adjustment agent is 0.5 to 3 isotonic concentration. The invention has the advantages that the preparation not only satisfies the fundamental needs of the human body on essential fatty acid, but also can greatly reduce the adverse effects caused by excessive polyunsaturated fatty acid and saturated fatty acid simultaneously. Compared with the common soybean oil fat emulsion, the invention can reduce lipid peroxidation to the utmost degree, improve immunity, increase the level of the active vitamin E Alpha-tocopherol in the human body, enhance the stability of the emulsion and speed up the synthesis of long-chain fatty acids.

The invention relates to the technical field of health-care food, in particular to cereal conditioning porridge for middle-aged and elderly people, comprising the following components in parts by weight: 10-15 parts of gordon euryale seeds, 10-15 parts of fermented soybeans, 10-15 parts of Chinese yams, 1-6 parts of coix seeds, 1-6 parts of haws, 3-9 parts of Chinese magnoliavine fruits, 1-5 parts of fragrant solomonseal rhizomes, 1-5 parts of longan aril, 2-5 parts of Chinese wolfberry fruits, 1-5 parts of raspberries, 1-5 parts of poria cocos, 1-5 parts of raw lily bulbs, 1-5 parts of lotus seeds, 0.5-3 parts of folic acid compounds, 3-8 parts of raw licorice roots and 0.5-3 parts of villous amomum fruits. The porridge has the advantages of being good in taste and remarkable in effects of coordinating gastrointestinal functions, enhancing immunity and preventing and treating cardiovascular and cerebrovascular diseases.

The invention relates to an ethyl acetate extract product of gentrin knotweed, a preparation method and an application thereof, the ethyl acetate extract product of the gentrin knotweed is prepared by the following steps: immersing gentrin knotweed by petroleum ether and percolating, recovering residues, volatilizing a solvent in the residues to dry, then extracting by ethanol, concentrating the extract to no alcohol taste, then extracting by using ethyl acetate with same volume of a concentrate, collecting an upper layer extract, evaporating to obtain the ethyl acetate extract product. The ethyl acetate extract product of the gentrin knotweed can prevent and treat senile dementia.

The invention discloses chaenomeles speciosa nakai and folium eriobotryae tea. The chaenomeles speciosa nakai and folium eriobotryae tea is prepared from chaenomeles speciosa nakai, folium eriobotryae, fructus amomi, fish scale foil, litchi leaves, kaffir lily leaves, cucumber leaves, sesame leaves, strawberry leaves, cuminum cyminum L., radix glycyrrhizae, longan leaves, black soya beans, mung beans and pig livers. The chaenomeles speciosa nakai, folium eriobotryae and fructus amomi are processed, and extract liquid A is obtained; the fish scale foil is processed, and extract liquid B is obtained; the black soya beans, mung beans, litchi leaves, kaffir lily leaves, cucumber leaves, sesame leaves, strawberry leaves, cuminum cyminum L. and radix glycyrrhizae are processed, and extract liquid C is obtained; the pig livers are processed, and extract liquid D is obtained. The extract liquid A, the extract liquid B, the extract liquid C and the extract liquid D are mixed and concentrated and subjected to spray drying, and a finished product of the chaenomeles speciosa nakai and folium eriobotryae tea with the water content being 2% is obtained. The chaenomeles speciosa nakai and folium eriobotryae tea is good in taste and rich in nutrition.

The invention discloses a preparation process of a camellia pollen beautifying yogurt. The process is as below: evenly mixing a fruit and vegetable compound freeze-dried powder, camellia pollen, a white sesame seed powder, a composite beautifying extract, sugar and fresh milk according to weight; homogenizing; sterilizing a primary pulp; inoculating yogurt fermentation bacteria in accordance with a conventional preparation process of yogurt; and refrigerating to obtain the product. The yoghurt provided by the invention has sweet taste, rich nutrition and beautifying effect as a dietary therapy. Compared with the prior art for producing yoghourt, the preparation process is simple and reasonable, and ensures the stability, high activity and functional nutrition of the product.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a consciousness restoring medicine / composition, a caulis piperis kadsurae-caulis sargentodoxae-caulis sinomenii consciousness restoring medicinal preparation and application of the medicine or the preparation. A caulis piperis kadsurae-caulis sargentodoxae-caulis sinomenii brain arousing composition provided by the invention is characterized by being mainly prepared from caulis piperis kadsurae, caulis sargentodoxae and caulis sinomenii. The brain arousing medicine / composition and the caulis piperis kadsurae-caulis sargentodoxae-caulis sinomenii brain arousing medicinal preparation have the beneficial effects that the caulis piperis kadsurae, the caulis sargentodoxae and the caulis sinomenii, the functions of which are mainly wind dispelling, blood circulation promotion and collateral dredging, are combined together, are assisted by other medicines, and jointly have the effects of preventing and treating cerebrovascular ischemia and a nervous-system disease, resisting aging and preventing and treating diseases of diabetes, a fatigue syndrome, senile dementia and the like.

The invention discloses a traditional Chinese medicine composition for treating the Alzheimer's disease. According to the invention, four medicinal materials, namely radix ginseng, fructus schisandrae, radix acanthopanacis semticosi and American ginseng, with remarkable sodium azide-induced PC12 cell injury resistance are screened out from 11 medicinal materials, and the radix ginseng, the fructusschisandrae, the radix acanthopanacis semticosi and the American ginseng form a compound; the mass ratio of the radix ginseng, the fructus schisandrae, the radix acanthopanacis semticosi and the American ginseng in the compound is (1-10): (1-10): (2-10): (0.5-8); pharmacological and pharmacodynamic experiments prove that the traditional Chinese medicine composition disclosed by the invention hasa remarkable effect on treating the Alzheimer's disease and can be used for preventing and treating the Alzheimer's disease; and the preparation method of the traditional Chinese medicine compositionfor treating the Alzheimer's disease is simple in process, beneficial to large-scale industrial production operation and small in pollution.

The invention relates to a decoding building block, which is characterized by consisting of a center shaft base, center splicing blocks and other splicing blocks, wherein the center shaft base is a round plate with a center shaft; each center splicing block consists of a center ring and more than one basic fan-shaped bodies positioned on the outer ring of the same layer of the center ring; the center ring is provided with a through hole matched with the center shaft; each other splicing block is formed by one basic fan-shaped body or correspondingly connecting more than two basic fan-shaped bodies in a certain direction; and the basic fan-shaped bodies and the center splicing blocks have the same height. More than five kinds of center splicing blocks are used; and the center splicing blocks in different kinds are different. More than ten kinds of other splicing blocks are used; and other splicing blocks in different kinds are different. The circle number is 2. The center shaft height is not smaller than the height of five layers of basic fan-shaped bodies. Compared with the prior art, the decoding building block has the following advantages and effects that the structure is relatively complicated; the complication degree is gradually improved stage by stage; the space imagination ability of children can be favorably improved; and senile dementia of old people can be prevented.