14results about How to "Raw material stability" patented technology

The application discloses a synthesis method of C3-substituted quinoxaline ketone derivatives and application thereof. A series of C3-substituted quinoxaline ketone derivatives with both terpene and quinoxaline ketone biological activity skeletons are obtained by using N-alkoxy phthalimide and quinoxaline ketone as starting substrates, under the catalysis of a photocatalyst and visible light irradiation, and at a temperature of 55-65 DEG C for 10-15 h. The application has the advantages of stable and easy-to-prepare raw materials, mild reaction conditions, simple experimental operation, good chemical selectivity and functional group tolerance, and is a green chemical synthesis method with good application prospect. The activity experiment results show that the synthesized C3-substituted quinoxaline ketone derivatives have good inhibiting effect on the growth of plant pathogenic fungi.

The present application discloses silane monomer, benzocyclobutene silicone resin, device and preparation method, belonging to the field of polymer materials. The chemical structural formula of the silane monomer is as follows: wherein, R1, R2, R3, R4, R5 are independently selected from the following groups: H, alkyl, alkoxy, alkenyl, phenyl; R6, R7, R8 are independently selected from the following groups: H, unsubstituted or substituted C1-C6 alkyl, unsubstituted or substituted C2-C6 alkenyl, unsubstituted or substituted phenyl, 4-vinyl-benzocyclobutene group or hydrolyzed group, and at least one of R6, R7, R8 is a hydrolyzed group; the hydrolyzed group is selected from substituted or unsubstituted amino, alkoxy, acyloxy or -Cl. The silane monomer can undergo a hydrolysis condensation reaction to synthesize a benzocyclobutene silicone resin with adjustable viscosity, without the need for a prepolymerization process, which is convenient for large-scale batch production.

The invention discloses a dermatophagoides pteronyssinus allergen Der p 1 recombinant protein, a preparation method, a kit and application, relates to the technical field of biology, and solves the technical problem that a detection result is not accurate enough when a crude extract is used for allergen detection. The method comprises the following steps: designing a pair of specific primers for amplifying Der p 1, carrying out amplification through PCR (Polymerase Chain Reaction), recovering a target band, connecting the target band with a cloning vector, converting to competent cell culture, extracting to obtain a recombinant plasmid containing a target gene, cloning the recombinant plasmid to a prokaryotic expression vector to obtain an expression vector containing the target gene, and carrying out high-throughput screening on the expression vector containing the target gene. The method comprises the following steps: transforming an expression vector containing a target gene into a host cell, inducing expression, and purifying to obtain Der p 1 recombinant protein with an amino acid sequence as shown in SEQ ID NO.1; the recombinant protein is high in biological activity, can be applied to preparation of a magnetic particle chemiluminescence detection kit, and is high in detection accuracy and good in kit stability.

The utility model relates to the technical field of blast furnace coal injection, and provides a blast furnace coal injection device which comprises a feeding cover and a plurality of bottom frames, the bottom frames are all fixed to the bottom of the feeding cover, a feeding pipeline is arranged on the outer side of the feeding cover, a feeding assembly is arranged in the feeding cover and the feeding pipeline, and the feeding assembly is arranged in the feeding cover and the feeding pipeline. The air inlet assembly is arranged at the inner bottom of the feeding cover, the feeding assembly comprises a spiral auger, the spiral auger is installed in a feeding pipeline, a dispersing cover is arranged on the periphery of the interior of the feeding cover, the feeding pipeline is communicated with the interior of the dispersing cover, a plurality of inlets are formed in the periphery of the bottom of the dispersing cover, and a pair of sliding rails is arranged at the top of the dispersing cover; a rotating cover is slidably connected to the sliding rail, a plurality of pushing plates are arranged on the bottom face of the rotating cover, and a protruding layer is arranged on the surface of the rotating cover. By means of the technical scheme, the technical problems that in the prior art, due to the technical bottlenecks of uneven feeding and excessive internal residues, the pulverized coal conveying efficiency is low, and combustion is insufficient are solved.

The invention discloses a synthesis method of a fluoroalkyl N-acylhydrazone compound containing a diphenyl phosphine oxide structural unit, and relates to the technical field of organic synthesis. Fluoroalkyl N-acylhydrazone and diphenylphosphine oxide are mixed in an organic solvent system, an oxidizing agent and metal salt are added, and the fluoroalkyl N-acylhydrazone compound containing the diphenylphosphine oxide structural unit is synthesized through a cross dehydrogenation coupling reaction. The diphenylphosphine oxide structural unit is introduced into a fluoroalkyl N-acylhydrazone molecule for the first time, the fluoroalkyl N-acylhydrazone compound containing the diphenylphosphine oxide structural unit is synthesized through a cross dehydrogenation coupling reaction, and the synthesis method has the advantages that reaction conditions are mild, raw materials are stable and easy to obtain, operation is easy, and the reaction yield is high.

The invention relates to stem cells, in particular to application of a subcellular extract of stem cells in preparation of a medicine for treating liver injury. Experiments prove that the prepared mesenchymal stem cell subcellular extract has a remarkable improvement effect on a carbon tetrachloride induced mouse hepatic fibrosis model in vivo and in vitro. The stem cell subcellular extract prepared by a mechanical disruption method can effectively alleviate the morphological problems such as hepatomegaly and rough surface, and improve the symptoms of hepatocyte injury and collagen deposition. In addition, the subcellular extract of the stem cells can significantly reduce the serum transaminase level of mice with hepatic fibrosis and improve the liver function. Meanwhile, by inhibiting the expression of fibrosis-related genes and inflammation-related genes in the liver, the subcellular extract of the stem cells exerts remarkable anti-fibrosis and anti-inflammatory effects. The umbilical cord mesenchymal stem cell subcell extract prepared by a mechanical crushing process provides a new method and thought for clinical treatment of liver injury.

This invention belongs to the field of traditional Chinese medicine, specifically relating to a traditional Chinese medicine composition for treating rosacea, its preparation method, and its application. This invention provides a traditional Chinese medicine composition for treating rosacea, comprising dandelion, purslane, sophora flavescens, sophora japonica flower, and rhubarb. The traditional Chinese medicine composition of this invention has the effects of clearing heat and detoxifying, reducing inflammation and antibacterial properties, cooling blood and promoting blood circulation, and repairing the skin barrier. It can be used to treat erythematous rosacea, relieving erythema, telangiectasia, papules, itching, and burning sensation on the skin, and reducing the risk of recurrence.

The invention belongs to the field of polymer preparation processes, and relates to a device and a method for preparing crude glycolide, which can be industrially implemented, can be continuously operated and can be operated on a large scale. The device comprises a dehydration unit, a polycondensation unit and a depolymerization unit which are sequentially connected, the dehydration unit comprises a dehydration kettle, a dehydration kettle heater, a dehydration tower and a dehydration tower condenser, the polycondensation unit comprises a polycondensation kettle and an optional pre-polycondensation kettle arranged at the upstream of the polycondensation kettle, and the depolymerization unit comprises a pre-depolymerization kettle, a depolymerization kettle and a crude glycolide condenser. The raw material glycollic acid or glycollic acid ester is subjected to dehydration separation, optional pre-polycondensation, polycondensation, pre-depolymerization, depolymerization and the like to finally obtain a crude glycolide product. Meanwhile, a small amount of non-condensable gas, depolymerization residues, water or alcohol and other byproducts are produced. The device provided by the invention can realize industrial large-scale continuous production, and improves the yield of the target product through various strengthening means.

The invention discloses an alkyl nitrile compound containing a fluoroalkyl N-acylhydrazone structural unit as well as a preparation method and application thereof, and belongs to the technical field of organic synthesis. The preparation method of the alkyl nitrile compound containing the fluoroalkyl N-acylhydrazone structural unit comprises the following steps: mixing fluoroalkyl N-acylhydrazone, cyclobutanone oxime ester, ferric salt and a solvent, and carrying out coupling reaction to obtain the alkyl nitrile compound containing the fluoroalkyl N-acylhydrazone structural unit. According to the invention, fluoroalkyl is introduced into the alkyl nitrile compound, so that the chemical, physical and biological properties of the alkyl nitrile compound, such as acid-base property, bioavailability, metabolic stability, fat solubility and protein binding capacity, can be changed, and the technical effect of the alkyl nitrile compound in subsequent application is improved.

The application belongs to the field of new energy materials, and provides a preparation method of stannous iodide, which comprises the following steps: adding hydriodic acid into ultrapure water to configure a solution A; adding a tin source into pure water, and then adding an antioxidant to form a solution B; adding the solution A into the solution B, heating and reacting, and then adding a reaction catalyst, stirring, and obtaining an orange-red solid; separating the orange-red solid from a liquid, washing, and vacuum drying to obtain a crude stannous iodide; performing a first heating process on the crude stannous iodide to separate the stannous iodide from oxidized impurities; and then performing a second heating process to obtain stannous iodide for perovskite batteries through high-temperature purification; wherein the tin source contains divalent tin ions. The preparation method has mild reaction conditions, simple raw material acquisition and preservation, high reaction efficiency, and the prepared finished product has high quality and high purity and is not easy to be oxidized, and is used in narrow-bandgap perovskite solar cells and laminated solar cells, and the photoelectric conversion efficiency is significantly improved.

The present invention provides a multifunctional anti-flocculation bio-based composite liquid silicon fertilizer and its synthesis method and application. The composite liquid silicon fertilizer of the present invention includes the following raw materials in mass fractions: 10-55 parts of soluble silicon, 1-2 parts of anti-flocculation bio-based stabilizer, 1-2 parts of bio-based organic solubilizer, 3-6 parts of synergist, 1-10 parts of bio-based buffer, 1-2 parts of ligand, and 80-120 parts of water. The raw materials of the silicon fertilizer of the present invention are easy to obtain and stable, and the use of bio-based components meets the needs of sustainable development; the preparation method is simple, easy to operate, the reaction conditions are easy to achieve, and it is safe and environmentally friendly. The prepared silicon fertilizer has good water solubility and stability, no flocculent precipitation is produced, low requirements for water quality, good resistance to hard water, and good compatibility; and the system is a buffer system, which can not only stabilize soluble silicon, but also ensure that soluble silicon is continuously converted into monosilicic acid, which is directly absorbed and utilized by crops, has good fertilizer efficiency, and can increase the silicon content of crops.

The invention discloses a production device and a production method of building gypsum powder, and the device comprises a hammer type beater used for removing water attached to the surface of desulfurized gypsum; the calcining furnace is used for carrying out two-step calcining on the desulfurized gypsum to remove crystal water of 3 / 2 of dihydrate gypsum in the desulfurized gypsum, so that the dihydrate gypsum is changed into semi-hydrated gypsum, and calcined gypsum is obtained; the ball mill is used for grinding the calcined gypsum; and the cooler is used for cooling the ground calcined gypsum. According to the device provided by the invention, attached water on the outer surface of the desulfurized gypsum is removed through the hammer type beater before the desulfurized gypsum is calcined, and the desulfurized gypsum is ground through the ball mill and aged through the aging bin after being calcined, so that the content of anhydrous gypsum in the calcined gypsum is reduced, the content of dihydrate gypsum in the calcined gypsum is reduced, and the content of semi-hydrated gypsum in the calcined gypsum is improved; the quality stability of building gypsum is improved, the product quality is improved, and stable raw material guarantee is provided for stable production of a production line.

According to the technical scheme, the bone nail locking plate machining device is characterized in that a base mechanism is arranged and used for solving the problem that the device is not stable enough in use, a mold mechanism is arranged and used for solving the problem that a mold cannot be replaced in the use process, and a cover plate mechanism is arranged and used for solving the problem that raw materials are not stable to fix in the machining process of the device; the working table is arranged to provide a machining platform for the device, the stability of the device during machining is improved, the device can be further stably installed on the platform through the first fixing hole, the stability of the device is further improved, the device can rapidly machine and manufacture samples through the sample groove through the sample groove, and the production efficiency of the device is improved; by arranging the notch, the device is more convenient when the sample groove is replaced, the convenience of the device is improved, by arranging the second limiting hole, the cover plate is installed more tightly and stably, the machining precision of the device is improved, and by arranging the raw material plate, the consumed raw material amount during machining of the device is reduced.

The utility model discloses environment-friendly coating automatic proportioning equipment which comprises a support, a mixing tank is arranged on the support, a tank cover is arranged at the top end of the mixing tank, a stirring assembly is installed on the tank cover, the bottom of the stirring assembly is inserted into the mixing tank, one side of the tank cover is connected with a waste gas treatment assembly, and the other side of the tank cover is connected with a water pump. The waste gas treatment assembly is filled with an adsorbent; a plurality of material storage tanks are arranged on one side of the support, metering pumps are arranged at the bottom ends of the material storage tanks, and the output ends of the metering pumps are connected with the mixing tank through guide pipes; a control box is arranged on the front face of the support, and the metering pump and the stirring assembly are electrically connected with the control box. The mixing tank and the storage tank are arranged, the metering pump is arranged at the bottom of the storage tank, and the control box and the metering pump are controlled, so that automatic proportioning of the coating is realized, various materials can be accurately conveyed according to set proportioning parameters, the proportioning precision is improved, the stable performance of the coating is ensured, and the production efficiency is improved. Therefore, the coating quality of the bearing with the base is improved.