31results about How to "The process is stable and feasible" patented technology

The invention discloses a manufacturing method of a large-calibre seamless titanium alloy barrel body, which comprises the steps of: 1, casting: casting titanium alloy raw materials into a large-calibre titanium alloy barrel blank by using a vacuum smelting furnace and through a vacuum smelting method; 2, hot isostatic pressing: performing the hot isostatic pressing for the large-bore titanium alloy barrel blank in an inert protective atmosphere by using a hot isostatic pressing device; 3, mechanical machining: processing a chamfer angle for spinning at the head of the large-bore titanium alloy barrel blank after the hot isostatic pressing by using mechanical processing equipment to obtain a spinning barrel blank; 4, spinning: thermally spinning the mechanically processed spinning barrel blank with the total deformation rate not less than 60% for many times by using spinning equipment to obtain a large-bore seamless titanium alloy thin-wall barrel body; and 5, subsequent treatment. The production process has short process flow, high yield, low cost, high utilization rate of materials and easy realization, and the defects of the large-bore seamless titanium alloy barrel body, such as complex process, high cost, low yield and the like of the traditional production process can be effectively solved.

The invention discloses a method for producing oriented electrical steel with excellent surface quality, and belongs to the technical field of oriented electrical steel production. The method comprises the following processes of: heating a casting blank at the temperature of between 1,000 and 1,190 DEG C, and then performing hot rolling; normalizing the hot rolled plate at the temperature of between 980 and 1,100 DEG C, and washing the plate by using acid; cold-rolling the plate to the thickness of a finished product under high rolling reduction rate of 86 to 93 percent; heating the cold rolled steel plate to the temperature of between 750 and 860 DEG C, and nitriding in ammonia-containing nitrogen and hydrogen mixed gas; performing decarburizing annealing at the temperature of between 800 and 860 DEG C; then coating a magnesium oxide isolation layer; raising the temperature to 1,200+/-50 DEG C at the speed of 10 to 20 DEG C per hour in the nitrogen and hydrogen mixed gas, preserving the heat for 10 to 20 hours in hydrogen, and completing high-temperature annealing to obtain a finished product of secondary re-crystallization textures; and coating an insulating stress coating. The method has the advantage of producing the oriented electrical steel without defect on the surface and with strong adhesive force and uniform magnesium silicate bottom layer.

The invention provides a method for processing red ginseng. The method comprises the following steps of 1, slicing sun-dried ginseng; 2, performing acid steaming on the sun-dried ginsengs; and 3, drying. The extracts obtained by the method are high in content.

The invention discloses a calcium dobesilate capsule and a preparation method thereof. The calcium dobesilate capsule is prepared from calcium dobesilate, croscarmellose sodium, magnesium stearate and polyvinyl pyrrolidone, wherein every 1000 calcium dobesilate capsules contain 500g of calcium dobesilate, 20-50g of croscarmellose sodium and 2-6g of magnesium stearate. In addition, a traditional preparation method is improved in the invention, and the improved method comprises the following steps: on the basis of taking the croscarmellose sodium as a disintegrating agent and taking the magnesium stearate as a lubricating agent, adding a proper amount of the polyvinyl pyrrolidone to prepare a bonding agent; preparing the bonding agent and the calcium dobesilate as well as the croscarmellosesodium into granules by a multi-step granulation method; and spraying the ethanol solution of the magnesium stearate onto the surfaces of the granules to obtain calcium dobesilate capsules with stable quality, high dissolution rate and small content uniformity.

The invention discloses rupatadine fumarate tablets and a preparation method thereof, belonging to the technical field of medicine. The tablets are prepared by making granules from rupatadine fumarate as active ingredient, and pharmaceutical adjuvants including a filler, a binder and a disintegrant, adding a lubricant, and making into tablets. Through the screening of the type and use amount of the filler, disintegrant, binder and lubricant and the use of specific sieving mesh to sieve raw materials during a preparation process, the prepared tablets have stable properties, good content uniformity, good dissolution, small tablet weight difference and high stability, so as to ensure in vivo bioavailability and clinical curative effect.

The invention relates to a tandem type shoe cover for machine service, which comprises a plurality of bag-shaped shoe cover bodies (3) made from flexible material (1) and elastic material (2); a bag-shaped opening (4) of each shoe cover body (3) is provided with a sliding connection devices (5) matched with a material feeding guide rail and a plurality of shoe cover bodies (3) are mutually connected with each other in series orderly to form a consistent monolithic construction. The shoe cover overcomes the defects of low output, high failure rate, etc., for the prior shoe cover dispensers and is a tandem type shoe cover for machine service that is used in combination with dragging automatic shoe cover dispensers.

The invention discloses a traditional Chinese medicine composition for treating cancer pain and ascites. The traditional Chinese medicine composition comprises, the rhizome of vincetoxicum atratum, the dried root of sophora flavescens, the dried root of Chinese angelica, the dried tuber of sparganium, the root and stem of curcuma zedoary, the rhizome of rheum officinale, bombyx batryticatus, the beehive of polistes japonicus sauss and the rhizome of paris polyphylla. The invention further provides a traditional Chinese medicine plaster for treating cancer pain and ascites and a preparation method thereof. The traditional Chinese medicine plaster comprises glycerol, NP-700, PVP K-90, EDTA-2Na, traditional Chinese extract and azone in the mass ratio of 11:5:0.7:0.1:8:0.9. The traditional Chinese medicine composition has the effects of clearing away heat and toxic material, activating blood circulation to dissipate blood stasis and relieving swelling and pain and can be used for treatinglung, liver, breast, thyroid malignant and benign tumors and unidentifiable poisoned sores and the like. By means of the application therapy of the external treatment of tumors, medicines are in harmonious proportion and applied to affected parts to achieve a direct anti-tumor effect, and the cancer pain and the complication such as malignant pleural effusion and ascites caused by the malignant tumors are effectively controlled to significantly improve the symptoms of patients and relieve the pain of the patients.

The invention relates to a pharmaceutical composition for chronic renal failure and a preparation method thereof. The pharmaceutical composition is prepared from deer blood crystals, poria cocos, dendrobium nobile and rhizoma atractylodis macrocephalae. The preparation method comprises the steps that the poria cocos, the rhizoma atractylodis macrocephalae and the dendrobium nobile are taken and decocted twice with water, after decoction liquid is concentrated, the deer blood crystals and auxiliary materials are added, and a preparation is prepared. The pharmaceutical composition has remarkable effects in the aspects of protecting the renal function and delaying the chronic renal failure.

The invention relates to an epitope composition, as well as a preparation method and uses thereof, in particular to an anti-atherosclerosis epitope composition, as well as a preparation method and uses thereof, which belongs to the technical field of biopharmacy. The epitope composition comprises fifteen epitopes having the characteristics of atherosclerosis autoimmune antigen in Mycobacterium bovine heat shock protein 65. The invention has the advantages that the obtained epitope composition can give full play to the immune efficacy of molecules similar to all-mHSP65 molecules by combining the epitopes having the characteristics of the atherosclerosis autoimmune antigen in a plurality of mHSP65 molecules; in addition, the epitopes having the characteristics of the atherosclerosis autoimmune antigen are chosen and the use of all-molecules is avoided, thereby reducing the influence on other autoimmune diseases, avoiding potential side effects, avoiding degradation problems brought by the own protease activity of the all-mHSP65 molecules and ensuring more stable and feasible process.

The invention provides an emulsifying technology for restoring cream. The technology comprises the following steps that 1, shea butter, olive oil, stearic acid and octadecanol are mixed, heated and stirred to obtain an oil phase ingredient; 2, water soluble raw materials are dissolved into deionized water, then, an emulsifying ingredient is added, heated and stirred to obtain a water phase mixture; 3, the water phase mixture is added into the oil phase ingredient, constant temperature emulsifying is performed, gradient cooling is performed to 35-40 DEG C, plant sterol lipidosome dry powder isadded, homogenous treatment is performed for 4-8 min, and oligopeptide-1, oligopeptide-2, dragon's blood and horse fat are subjected to homogenous treatment for 3-5 min. According to the emulsifying technology for restoring cream, by optimizing the oil phase raw materials, the ingredient ratio thereof, the emulsifying ingredient and the content thereof, the anti-wrinkle restoring cream containingplant sterol lipidosome with the good physical stability can be obtained, the dispersibility and biological utilizing rate of plant sterol in the repairing cream are increased, and therefore the effects of resisting oxidation, flatting thin veins and resisting wrinkles of the restoring cream are improved.

The invention relates to a method of enriching and purifying total flavonoids of all grass of cardamine tangutorum. The method comprises the following steps: (1) preparing extract of the all grass ofcardamine tangutorum; (2) loading the extract of the all grass of cardamine tangutorum on a macroporous resin adsorption column, wherein the loading quantity is 8-48ml of the extract for each gram ofdry macroporous resin, and the flow is 3-4BV/h; after the loading, washing with water and then eluting with ethanol, wherein the volume fraction of ethanol is 10-90%, and the flow is 2-8BV/h; collecting the eluent and detecting the content of total flavonoids. The technology is stable and feasible, provides test data and scientific basis for the enrichment and purification of the total flavonoidsof the all grass of cardamine tangutorum, and lays a foundation for further studying the active chemical ingredients in the all grass of cardamine tangutorum and studying the digestion promoting function of the all grass of cardamine tangutorum.

The invention discloses a traditional Chinese medicine malt germination processing method. The method comprises the following steps: S1, washing raw barley to remove impurities; S2, adding sufficient water into the raw barley in the step S1, and conducting soaking for 5 hours; S3, fishing out the soaked barley malt and placing the soaked barley in a drainage container, spraying water every day under the conditions that the temperature is 25 DEG C and the humidity is 70% to keep the barley malt moist, and stopping sprouting when the barley sprouts to the length of 0.5 cm, wherein the mass ratio of the water spraying amount every day to the barley malt is 1:1; and S4, drying the germinated barley at 70 DEG C under normal pressure for 12 hours, wherein the water content of the dried barley malt is 2.07%. In order to solve the problem that specific parameters are not provided in an existing barley germination process, the invention provides a better implementation method for germination processing of traditional Chinese medicine malt, the process is stable and feasible, the drug property of the malt is guaranteed, and the practicability is very good.

The invention relates to a new process of amino G acid ammonification production, belonging to the field of organic chemistry. In the new process provided by the invention, the finished product of amino G acid is prepared by taking ammonium bicarbonate as an aminolysis agent by the steps such as dosing, low-temperature ammonification and high-temperature high-pressure ammonification; the yield of amino G acid is increased to over 90% from 82% before, and the product purity is improved by 2%. Meanwhile, by adopting the process, the pressure maintained by an ammonification reaction kettle is reduced from 1.2MPa to 0.5MPa, and the process has the characteristics of high safety coefficient and stability.