The invention relates to the field of medicines, in particular to health-care products capable of reducing high blood pressure, high blood sugar and high blood lipid, resisting radiation, restrainingtumors and improving immunity, and a preparation method. The health-care products comprise the following raw materials of radix astragali, tricholoma matsutake, glossy ganoderma, lethariella cladonioides, arctium lappa roots and malabar spinach. The preparation method comprises the following steps of (1) performing crushing: performing freeze drying on the malabar spinach in the raw materials, then performing crushing, baking the rest raw materials, and then performing crushing; (2) performing fermentation: mixing the crushed materials in proportion, performing soaking with hot water, performing draining and performing fermentation; (3) performing granulation: performing granulation on the fermented materials with a granulator, and performing drying; and (4) performing roasting: after granulation, performing roasting at the temperature of 80-100 DEG C through a frying machine for 5-8 minutes, and then performing roasting at the temperature of 120-160 DEG C for 2-5 minutes. The medicineefficacy can penetrate all parts of bodies, and edible and medicinal raw materials are adopted, so that the health-care products are free from side effects, are beneficial for five internal organs after being eaten for a long term, can replenish vital essence, calm qi and blood, and systematacially and comprehensively regulate human bodies, and has good health-care effects of reducing high bloodpressure, high blood sugar and high blood lipid, resisting radiation, preventing radiation, resisting haze and improving immunity.