72 results about "Oleanolate" patented technology

The invention relates to bionic skin barrier cream with a three-layer phospholipid structure and a preparation method of the bionic skin barrier cream, and belongs to the technical field of cosmetics, the bionic skin barrier cream comprises the following raw materials: lecithin, wax ester, triglyceride, composite ceramide, phytosterol oleate, squalane, an antioxidant, polyol, composite amino acid, pyrrolidone carboxylic acid, urea and arginine. A stabilizing agent, a treating agent and the balance of deionized water. The bionic skin barrier cream prepared by the invention has a three-layer phospholipid structure, and compared with a double-layer phospholipid structure in the market, the firmness and hydrophobicity of the double-layer structure are further improved by the added third-layer structure, so that the prepared bionic skin barrier cream has outstanding waterproof, sweat-resistant and light pollution-resistant effects; in addition, the wax ester, the triglyceride, the phytosterol oleate, the pyrrolidone carboxylic acid and the urea selected in the invention have a synergistic effect, and can generate excellent moisturizing and repairing effects and certain protection effects.

The invention relates to the technical field of cosmetics, and particularly discloses emulsion type foaming cleaning scrub cream with a skin care effect and a preparation method of the emulsion type foaming cleaning scrub cream. The scrub cream is prepared from the following raw material components in percentage by mass: 8 to 15 percent of glycerol, 0.2 to 0.9 percent of sodium hydroxide, 0.3 to 0.8 percent of citric acid, 0.03 to 0.2 percent of EDTA (Ethylene Diamine Tetraacetic Acid) disodium, 0.5 to 1.5 percent of an auxiliary agent, 1.5 to 3.0 percent of a thickening agent A, 1.5 to 3.0 percent of a thickening agent B, 5.86 to 1457 percent of an emollient, 12 to 22 percent of a surface active foaming agent, 0.8 to 3.0 percent of an emulsifying agent, 2.5 to 13 percent of a cutin stripping agent, 0.7 to 1.3 percent of a preservative, 0.32 to 0.92 percent of a skin conditioning agent and the balance of water, the skin conditioner is a mixture prepared from sodium hyaluronate, tocopherol, papain, nicotinamide, carnosine, panthenol and phytosterol oleate.

The invention relates to a silicon compound-free carbon fiber precursor oiling agent as well as a preparation method and application thereof. The silicon compound-free carbon fiber precursor oiling agent comprises the following components: oleate, alkynol ester, a polyoxyethylene ether derivative, an emulsifier, an antistatic agent and a defoaming agent. According to the oiling agent disclosed by the invention, the carbon fiber precursor has excellent lubricity, heat resistance and antistatic property, so that the carbon fiber obtained by pre-oxidizing and carbonizing the precursor has excellent mechanical property. The carbon fiber precursor oiling agent is simple in preparation process, has excellent film-forming property, heat resistance and stability, and can eliminate silicon powder pollution in the production process of polyacrylonitrile-based carbon fibers, prolong the running time of a carbon fiber production line and reduce the production cost.

The invention provides a composite oil phase material for improving water resistance and explosion performance of a porous granular ammonium nitrate fuel oil explosive. The composite oil phase material comprises the following raw materials in parts by mass: 80-100 parts of naphthenic oil, 2-7 parts of an amino-containing dispersant, 1-5 parts of a nanoscale molecular sieve and 0.3-3 parts of an oleate derivative stabilizer. The composite oil phase material can effectively improve the explosion performance and the water resistance of the on-site mixed porous granular ammonium nitrate fuel oil explosive. The raw materials are environment-friendly and easy to obtain, and high popularization value is achieved. The composite oil-phase material provided by the invention is high in flash point and low in condensation point, can replace diesel oil with the grade of minus 40 DEG C to minus 20 DEG C to be applied to preparation of a porous granular ammonium nitrate fuel oil explosive mixed and loaded on site in winter, the intrinsic safety of the explosive production process is improved, and the explosive preparation cost is reduced. The composite oil phase material provided by the invention can also provide good weak alkaline water resistance for the porous granular ammonium nitrate fuel oil explosive.

The invention provides a high-temperature-resistant water shutoff agent as well as preparation and application thereof. The water shutoff agent is prepared from the following components in parts by weight: 100 to 110 parts of sodium lauryl alcohol phthalate, 45 to 55 parts of polyoxyethylene sorbitan monooleate, 60 to 70 parts of lignin surfactant, 65 to 75 parts of alpha-olefin sulfonate and 330 to 380 parts of oleic acid. The preparation process of the water shutoff agent comprises the following steps: adding the sodium lauryl alcohol ester phthalate and the polyoxyethylene sorbitan monooleate into a reaction kettle, and uniformly stirring to obtain a first reaction solution; adding a lignin surfactant and alpha-olefin sulfonate into the first reaction solution at one time, and uniformly stirring to obtain a third reaction solution; equally dividing oleic acid into two groups, adding one group of oleic acid into the third reaction solution, and uniformly stirring to obtain a fourth reaction solution; and adding another group of oleic acid into the fourth reaction liquid, uniformly stirring, and standing to obtain the water shutoff agent. The problems that a water plugging agent is poor in plugging effect in a high-temperature oil reservoir and low in crude oil recovery rate can be solved.

The application discloses a 100% natural source reverse micelle essential oil and a preparation method thereof, and the preparation raw materials comprise 0.6-13 parts of emulsifiers and 20-100 parts of natural source oils in terms of mass fraction. The combination of PCA glyceryl oleate and polyglycerol nonionic surfactants has a mass ratio of (0.5-0.8):(2-2.5), and the combination of polyglyceryl-2 isostearate and polyglyceryl-4 oleate has a mass ratio of (1-1.5):(0.8-1), so that the reverse micelle essential oil can be constructed, the essential oil has the advantages that the essential oil is skin-friendly and non-greasy, can be compatible with hydrophilic active ingredients and oleophilic active ingredients, and can effectively moisturize and nourish the skin.

The application belongs to the technical field of anti-aging skin care product preparation, and discloses a composition containing a composite exosome-polypeptide, a preparation method thereof and application of the composition in cosmetics. The composition contains, in terms of mass fraction, 3.0%-7.0% of an exosome-polypeptide composite wrapped by a biomimetic liposome, 4%-9% of a plant active synergistic extract, 15%-20% of a temperature-sensitive moisturizing sustained-release system, 3%-6% of a lipid barrier repair agent, 0.3%-0.8% of an antioxidant stabilizer, and the rest is a basic base; the exosome is composed of membrane pod huangqi root exosome, salvia miltiorrhiza exosome and long life flower exosome; the polypeptide is composed of palmitoyl tripeptide-5 and acetyl hexapeptide-8; and the biomimetic liposome is composed of phosphatidylcholine, ceramide NP and phytosteryl oleate. The application is compounded by the composite exosome-polypeptide-multiple effect component, hierarchical synergy is achieved, multiple-dimensional aging targets are covered, the transdermal rate is improved, the activity is retained for a long time, the barrier repair and skin quality adaptation are considered, and the anti-aging performance is excellent.

The invention discloses a carbon dioxide capturing agent based on organic amine as well as a preparation method and application thereof. The carbon dioxide capturing agent is prepared from the following raw materials in parts by weight: 60 to 80 parts of organic amine, 10 to 20 parts of octanoic acid, 3 to 7 parts of carbon powder, 5 to 10 parts of urea, 10 to 20 parts of polyethylene glycol 400, 1.8 to 4 parts of polyethylene glycol monooleate, 2 to 4.05 parts of choline chloride and 40 to 60 parts of solvent. The absorption performance and regeneration effect of the capture agent on carbon dioxide can be improved.

According to the green and environment-friendly antibacterial polyurethane adhesive and the synthesis method thereof, renewable sorbitan oleate and tannic acid are introduced into a waterborne polyurethane adhesive, so that the environmental protection property of the adhesive is improved, and the water resistance and flowability of the adhesive can be effectively improved; and the adhesive is endowed with antibacterial and mildew-proof properties and higher bonding strength. The sorbitan oleate and the tannic acid are both subjected to chemical reaction with the toluene diisocynate, and polyhydroxy structures of the sorbitan oleate and the tannic acid promote cross-linking among molecules and enhance a molecular network of the adhesive, so that the cementing performance of the adhesive is improved; the hydroxyl position of sorbitan oleate and a long alkane chain also increase the synthesis yield of the adhesive and the toughness and water resistance of the product, tannic acid is used as a cross-linking agent on one hand, and on the other hand, the interaction of a polyphenol structure in tannic acid and an adhesive matrix can inhibit the growth of mould and bacteria on the other hand, so that the antibacterial and mildew-proof properties of the adhesive are also improved, and the service life of the adhesive is prolonged. And the mildew-proof capability is improved by more than 80%.

The invention relates to the field of heat-conducting oil, and discloses high-temperature-resistant heat-conducting oil and a preparation method thereof. The high-temperature-resistant heat-conducting oil is prepared from the following raw materials in percentage by weight: 5-10% of base oil, 62-75% of complex ester, 5-10% of a high-temperature-resistant agent, 8-12% of an emulsifier, 4-8% of a purification dispersant, 1.8-2.7% of an antioxidant and 0.1-0.3% of a defoaming agent, the complex ester is composed of pentaerythritol tetraoleate, trimethylolpropane oleate and a ricinoleic acid polyester compound; the purification dispersant is prepared from polyethylene glycol monododecyl ether and dodecyl benzene sulfonic acid triethanolamine salt. The heat conduction oil has high heat transfer efficiency and high-temperature stability, carbon deposition is not prone to occurring when the heat conduction oil is used under the high-temperature condition for a long time, lubricating and cooling performance is excellent, and the heat conduction oil is suitable for heat transfer systems needing long-term high-temperature operation, such as industrial boilers and die-casting dies.

The invention belongs to the field of skin care materials, and provides a bionic cuticle moisturizing barrier composition and a preparation method thereof. Sodium pyrrolidone carboxylate, an amino acid compound, bimodal molecular weight sodium hyaluronate, trehalose and betaine are used as water-phase humectants, squalane, caprylic / capric triglyceride and phytosterol oleate are used as oil-phase carriers, and cholesterol, hydrogenated lecithin, octyldodecanol and ceramide NP are used as sebum-like barrier components. A layered liquid crystal and alpha gel double-network structure is constructed through a segmented phase inversion emulsification and microjet homogenization process, and a narrow distribution system with the emulsification drop diameter D50 being 0.3-5 microns and SPAN being not larger than 1.2 is achieved. The technical problems that a high-density barrier, ventilation and refreshing are difficult to obtain at the same time, rheological unbalance of a high-solid-content system is caused, and irritation and phase structure damage are caused by traditional high-energy homogenization are solved, and the application value in sensitive skin and barrier damaged skin care is achieved.

The invention discloses high-magnetic-induction oriented silicon steel rolling oil which comprises the following components in parts by weight: 70-90 parts of synthetic ester, 5-15 parts of white oil, 5-10 parts of a lubricating additive, 2-5 parts of an emulsifier, 0.5-2 parts of an antioxidant and 1-3 parts of an anti-rust additive. The synthetic ester is selected from any one of trimethylolpropane coconut oleate, butyl stearate, trimethylolpropane oleate or trimethylolpropane triisostearate, and the emulsifier is composed of a cationic surfactant and a nonionic surfactant in a mass ratio of (1-1.5): 1. Compared with traditional rolling oil, the rolling oil provided by the invention adopts a brand new combination of the emulsifier and the dispersant, the stability and dispersion performance of the rolling oil during emulsification use are improved, the obtained rolling oil emulsion is stable and wide in applicable pH range, and the rolling oil also has excellent lubricating and anti-rust performance, is low in cost and is suitable for large-scale popularization.

The application provides a tranexamic acid-glutathione compound cream and a preparation method thereof, adopts a W1 / O / W double emulsion phase structure design, encapsulates reduced glutathione in an acidic inner water core, stabilizes an oil phase by using hydrogenated lecithin and sorbitan sesquioleate, and constructs a lamellar gel network in an outer water phase containing tranexamic acid, so as to realize a sub-micron dispersion system with a particle size D50 of 0.30-0.80 microns, a polydispersity index of 0.15-0.25 and a viscosity of 2.0-8.0 Pa seconds, the encapsulation rate of glutathione is not less than 70%, and the headspace oxygen content is not higher than 1.0%, three technical contradictions of a high yield viscoelastic structure and a low shear damage inner core integrity coupling conflict, a smooth low skin feeling and a high barrier anti-oxidation and anti-leakage coexistence problem and a low surface activity sensitive skin compatibility and a sub-micron low PDI dispersion stability are solved, and the application has wide application values of improving uneven skin color, lightening color spots, brightening skin color and soothing and repairing.

The invention provides a ketorolac patch composition, a ketorolac patch as well as a preparation method and application of the ketorolac patch. The ketorolac patch composition comprises an active component, a matrix material and a transdermal enhancer, the transdermal enhancer comprises at least two of lactic acid, oleic acid, phosphoric acid, tartaric acid, citric acid, fumaric acid, malic acid, isopropyl myristate, propylene glycol monolaurate, glyceryl monolinoleate, glyceryl triacetate, diisopropyl adipate, triethyl citrate, polyglycerol oleate and sorbitan oleate (Span 80); preferably, the transdermal enhancer is prepared from at least two of isopropyl myristate, triethyl citrate, polyglycerol oleate, glyceryl triacetate, oleic acid, sorbitan oleate (Span 80), lactic acid and citric acid; the transdermal enhancer provided by the invention comprises the compounding of at least two of the substances, so that the transdermal diffusion performance of the ketorolac patch composition can be greatly improved.

The invention provides a method for preparing 1, 3-dioleic acid-2-palmitic acid triglyceride by an enzyme method, and relates to the technical field of preparation of the 1, 3-dioleic acid-2-palmitic acid triglyceride. The 1, 3-dioleic acid-2-palmitic acid triglyceride is prepared by mixing lard oil with cholesterol mass content lower than 0.05% and oleate, performing low-temperature high-pressure treatment, performing variable-pressure enzymolysis, separating lipase, and performing crystallization washing, thereby obtaining a final product. According to the method, the defects in the prior art are overcome, the high-purity 1, 3-dioleic acid-2-palmitic acid triglyceride can be prepared from the lard oil and the oleate, the lipase can be used for multiple times, the preparation efficiency of the 1, 3-dioleic acid-2-palmitic acid triglyceride is comprehensively improved, and the preparation cost is reduced.

The invention discloses a cosmetic composition with rapid emulsification and layering characteristics and a preparation method and application thereof, the cosmetic composition comprises a first component and a second component, the first component comprises a water phase and an emulsifier, and the second component comprises an oil phase; the water phase comprises water and an electrolyte demulsifier, and the oil phase comprises grease; the emulsifying agent is prepared from sorbitol polyether-30 tetraoleate and polyglycerol-4 decanoate, and the feeding mass ratio of the sorbitol polyether-30 tetraoleate to the polyglycerol-4 decanoate is 1 to (1 to 15); the cosmetic composition has the characteristics of rapid emulsification and layering, can be directly mixed at normal temperature during preparation, is simple to operate, avoids the use of PEG emulsifiers, improves the mildness, and in the actual use process, triggers the texture transformation of the product through physical shaking, and realizes the double-state experience of mixing before use and activation during use.

The invention belongs to the technical field of cosmetics, and particularly relates to a composition and application thereof. The invention relates to a composition, in particular to a composition with repairing and anti-wrinkle effects and application thereof. The invention provides a composition. The composition comprises a first active composition and a second active composition, the first active composition comprises sodium hyaluronate, phytosterol oleate and a polygonatum odoratum extract; and the second active composition comprises any one of the following two components: dipalmitoyl hydroxyproline or palmitoyl tripeptide-1. The applicant creatively discovers that by using the composition disclosed by the invention, through the synergistic effect of all the components, excellent repairing and anti-wrinkle effects can be formed.

The invention relates to the technical field of supercritical carbon dioxide flooding crude oil extraction, in particular to a supercritical carbon dioxide thickener oligomeric glycerol phenyl oleate and application thereof. The thickening agent comprises oligomeric glycerol phenyl oleate. The low polyglycerol phenyl oleate is used as the supercritical carbon dioxide thickening agent, so that the viscosity of the supercritical carbon dioxide solution can be remarkably improved. The oligomeric glycerol phenyl oleate is easy to prepare, low in production cost, environment-friendly and suitable for large-scale popularization and application.

The invention discloses a novel sodium aluminate seed crystal decomposition crystallization auxiliary agent and a preparation method thereof, and the novel sodium aluminate seed crystal decomposition crystallization auxiliary agent comprises the following components by mass: 0.1%-1% of sorbitan oleate sodium sulfonate, 0.1%-1% of secondary alkyl sodium sulfonate, and the balance of distilled water. The preparation method comprises the following specific preparation steps: weighing sorbitan oleate sodium sulfonate and secondary alkyl sodium sulfonate according to a ratio, and putting the weighed materials into a beaker; and adding distilled water into the beaker until the total weight is 100g, stirring for 5-10 minutes, and dissolving into uniform liquid. According to the invention, the independently designed and synthesized sorbitan oleate sodium sulfonate and the anionic surfactant secondary alkyl sodium sulfonate are compounded, and the two components have a synergistic enhancement effect, so that agglomeration among aluminum hydroxide particles is effectively promoted, and the decomposition rate of a sodium aluminate solution is improved. The composition is simple, the preparation technology is simple, industrial production is easy, and the good industrial application prospect is achieved.

The invention relates to the technical field of pharmaceutical preparations, and particularly discloses an ophthalmic sustained-release adhesive gel containing a copolymer and oleate and a preparation process. The preparation comprises a block copolymer, oleic acid p-hydroxyphenethyl alcohol ester, structured phospholipid, a mucous membrane adhesion and permeation enhancing synergist, an active drug and a plurality of functional auxiliary materials, the preparation method comprises the following steps: preparing a co-assembled dispersion and a drug suspension, constructing a gel matrix, mixing and integrating functional auxiliary materials in a stepped manner, performing intermittent ultrasonic treatment and programmed ripening to optimize a system, and finally sterilizing and sub-packaging. The preparation can be used for treating chronic eye diseases such as glaucoma and the like, and has the advantages of lasting and stable drug release, strong mucous membrane adhesive power, good cornea permeation effect and capability of giving consideration to both mechanical properties and long-term stability; in addition, the preparation method provided by the invention has the advantages of ordered steps and controllable process, can effectively avoid component agglomeration, ensures the uniformity and performance stability of the preparation, and is suitable for large-scale production.

The invention belongs to the technical field of anti-wear agents, and particularly relates to a lubricating oil anti-wear agent and a preparation method thereof. The lubricating oil anti-wear agent is prepared from the following raw materials: sulfur modified n-butyl oleate, molybdenum dialkyldithiocarbamate, di (2-ethylhexyl) phosphate ammonium salt, boron-nitrogen modified pentaerythritol trioleate, a purification dispersant, an antioxidant, a pour point depressant, an anti-foaming agent and the balance of base oil. According to the lubricating oil anti-wear agent disclosed by the invention, sulfur modified n-butyl oleate, boron-nitrogen modified pentaerythritol trioleate, molybdenum dialkyldithiocarbamate and di (2-ethylhexyl) phosphate ammonium salt are used as main anti-wear components, and the four components have a synergistic effect; and the prepared lubricating oil anti-wear agent has good wear resistance under medium and extreme pressure working conditions.

The present application provides emulsified kerosene, which comprises an emulsifier and kerosene, the emulsifier being selected from C10-16 alcohol alkoxylate and / or polyethylene glycol 600 monooleate. The mass percentage of the emulsifier is 10% to 35% of the kerosene; when the emulsifier is C10-16 alcohol alkoxylate and polyethylene glycol 600 monooleate, the mass ratio of C10-16 alcohol alkoxylate to polyethylene glycol 600 monooleate is 0.3-3:1. The combined collector provided by the present application can synergistically regulate the hydrophobicity of the surface and edge of molybdenite, significantly improve the flotation performance of fine-grained molybdenite, and meanwhile, good compatibility is shown between the components of the collector. The combined collector provided by the present application is significantly superior to emulsified kerosene or non-ionic surfactant used alone in terms of collecting effect, and has lower dosage and cost.

The present invention provides a new use of a class of compounds in the inhibition of alpha-1,6-fucosyltransferase. Specifically, the present invention provides the use of an active ingredient comprising one or more compounds containing the structure of - (M) n or not containing the structure of - (M) n such as NH125, chlorhexidine, sulfo-N-succinimidyl oleate, etc., or a pharmaceutically acceptable salt, isomer or mixture of isomers, solvate or crystal form thereof, as an alpha-1,6-fucosyltransferase targeted inhibitor in the treatment or prevention of related diseases.

The application relates to the field of heat-conducting oil, and discloses a high-temperature-resistant heat-conducting oil and a preparation method thereof. The high-temperature-resistant heat-conducting oil is prepared from the following raw materials in percentage by weight: base oil 5-10%, composite ester 62-75%, high-temperature-resistant agent 5-10%, emulsifier 8-12%, cleaning dispersant 4-8%, antioxidant 1.8-2.7%, and defoaming agent 0.1-0.3%; the composite ester is composed of pentaerythritol tetraoleate, trimethylolpropane oleate and castor oil acid polyester compound; and the cleaning dispersant is composed of polyethylene glycol monododecyl ether and dodecyl benzene sulfonic acid triethanolamine salt. The heat-conducting oil has high heat transfer efficiency and high-temperature stability, is not prone to carbon deposition under long-term high-temperature conditions, has excellent lubricating and cooling performance, and is suitable for heat transfer systems which need long-term high-temperature operation, such as industrial boilers, die-casting dies and the like.

The present invention relates to the field of cosmetics technology, specifically to a repairing composition for lowering the freezing point of essential oils and a preparation method thereof. The composition comprises slowly dripping phytosterol / octyldodecanol lauroyl glutamate into jojoba seed oil stirred at 200 rpm. The stirring speed is then reduced, sorbitan oleate is added, and the mixture is stirred until uniform. A ginseng root extract extracted with supercritical CO2 is then added to produce the repairing composition. In the present invention, the phytosterol / octyldodecanol lauroyl glutamate is slowly dripped into the stirred jojoba seed oil to form fine microspheres. The sorbitan oleate's opening-like structure then separates the microspheres, reducing the interaction between them and lowering the freezing point of wax and ester components in the oil. The ginseng root is then extracted with supercritical CO2 to extract more volatile oils and lower the freezing point of the ginseng root extract. The repairing composition not only has a lower freezing point but also simultaneously helps lower the freezing point of the essential oil to which it is added.

This invention relates to a cosmetic material composition with a flexible, enhanced liquid crystal structure containing elliptical or amorphous oil particles, formed from any one or more of olive oil esters and oleate surfactants, higher alcohols, and liquid crystal forming surfactants. The cosmetic material composition of this invention exhibits enhanced five-layer deep moisturizing function, instant moisturizing elasticity, soothing effect on skin damage under physical stimulation, and moisture retention compared to existing liquid crystal emulsions, through the synergistic effect between liquid crystals similar to intercellular lipids of the skin and flexible oil particles. It also possesses excellent moisture-protective film formation efficacy.

The invention discloses a composite microsphere containing a silk material and a preparation method and application of the composite microsphere, and relates to the technical field of biomedical materials. The shell raw materials comprise a chitosan solution, a cross-linking agent and a catalyst; the encapsulated microsphere raw materials comprise microspheres and vesicles; the raw materials of the microspheres comprise a silk material, an extracellular matrix, poly-desoxyribonucleic acid and a cationic substance. Raw materials of the vesicles comprise an oleate solution and a glutamic acid solution.

The present application belongs to the technical field of external preparations of traditional Chinese medicine, and relates to a cream containing imperatorin and capable of promoting skin wound healing and a preparation method thereof. The cream takes imperatorin and puerarin as core effective components, magnesium lithium silicate and sodium hyaluronate as synergistic repair components, sorbitan oleate and lanolin as emulsifiers, refined sesame oil, squalane and white petrolatum as oil phase matrix, and further includes glycerol, and the rest is deionized water. Animal experiment results show that the cream can promote collagen fiber generation of granulation tissue, promote polarization of repair type macrophages, significantly optimize repair quality and reduce scar formation while improving wound healing rate, and has good safety. The preparation process is stable and controllable, and is suitable for industrial production. The cream can be used for I and II degree mild burn and scald, skin abrasion and other traumatic wounds, and is also suitable for skin problems such as postoperative wound repair of medical beauty and hand and foot chapped skin, has wide clinical application range, and has good application prospect and popularization value.

The invention discloses a silicon resin composition as well as a preparation method and application thereof, and relates to the technical field of high polymer materials. The silicon resin composition disclosed by the invention is prepared from alpha, omega-dihydroxy polydimethylsiloxane, a ketoxime cross-linking agent, a treating agent and an auxiliary agent, the treating agent comprises alcohol anhydride oleate. According to the silicon resin composition, migration of a ketoxime cross-linking agent is avoided, the problem of oil production of an existing silicon resin product is solved, meanwhile, in the presence of the filler, the dispersity of the filler in a system can be improved through the use of the alcohol anhydride oleate, and the obtained silicon resin composition is good in mechanical property and adhesive property and good in mechanical property. Compared with the conventional ketoxime type sealant (RTV-1), the ketoxime type sealant has the advantages that the oil outlet phenomenon is reduced, and the ketoxime type sealant is high in mechanical property and adhesion and suitable for door and window sealing or electronic and electric appliance sealing.