36 results about "Sodium phenylacetate" patented technology

The invention relates to a method for recovering phenylacetic acid from a benzylpenicillin potassium lysis solution and belongs to the technical field of pharmacy. The method for recovering the phenylacetic acid from the benzylpenicillin potassium lysis solution comprises the steps that the benzylpenicillin potassium lysis solution is extracted through an organic solvent; an organic phase is decolored through an activated carbon and alkalized through a sodium hydroxide solution; and the obtained alkalized water phase is oxidized with hydrogen peroxide and decolored with activated carbon so that a sodium phenylacetate aqueous solution with a light color can be obtained, the sodium phenylacetate aqueous solution is acidized and crystallized through concentrated sulfuric acid, washed with cold water and dried, and phenylacetic acid is obtained. The obtained phenylacetic acid product is high in quality, no waste difficult to deal with is generated in the recovering process, and the method is suitable for large-scale application.

The invention discloses a production process of high-quality phenylacetic acid, and relates to the technical field of phenylacetic acid production. The production process includes the following steps that 1, benzyl cyanide is added dropwise into a water solution of sodium hydroxide or potassium hydroxide in a reflux state, a water solution of sodium phenylacetate or potassium phenylacetate is obtained through heat preservation, and the pH is adjusted to be 6-8; 2, extraction and impurity removal are carried out, wherein an extraction agent used in extraction is one or more of benzene, alkyl halide and ether organic solvent; 3, the water solution of sodium phenylacetate or potassium phenylacetate obtained after extraction enters an inlet in the upper portion of a desorber, and nitrogen is blown into an inlet in the lower portion of the desorber to desorb and separate the contained organic solvent; 4, activated carbon is used for adsorbing the water solution of sodium phenylacetate or potassium phenylacetate obtained after desorption; 5, water solution of sodium phenylacetate or potassium phenylacetate obtained after adsorption is acidized to obtain high-quality phenylacetic acid. The process can effectively increase the phenylacetic acid content and achieve continuous operation and is high in yield.

The invention relates to a method for synthesizing furbenicillin acid, which comprises the following steps: adding 6-APA into halogenated alkane, and dissolving the 6-APA by an alkalizer to obtain a solution a; dissolving alpha-furanuride sodium phenylacetate in the halogenated alkane, and esterifying the solution to obtain an estolide solution b of alpha-furanuride phenyl acetic acid; and after the solution a and the solution b are subjected to a condensation reaction at a temperature of between 20 DEG C below zero and zero DEC, adjusting pH to be between 5.5 and 6.7 to make the solution split phase, reclaiming an organic phase, adding an extracting agent into a water phase, acidifying and layering the solution, and dripping the extracting agent into the organic phase to separate out furbenicillin acid crystal. The method for synthesizing the furbenicillin acid fully adopts water avoidance reaction, the yield of products reaches more than 78 percent, the purity is improved to more than 90 percent, the content of the total impurities is reduced to below 10 percent, and the method has the advantages of simple production process and stable quality.

The invention discloses an application method of single body entry type ceramic wood. During ceramic wood preparing, sodium phenylacetate and chloropropene prepared through the reaction of phenylacetic acid and sodium hydroxide enters wood, allyl phenylacetate is generated, then, a high-molecular polymer is generated, and a net-shaped structure is formed by the high-molecular polymer and wood fiber. The interior-exterior structure, rigidity and strength of the ceramic wood can be consistent, and the interior and exterior waterproof performance, corrosion resisting performance, mothproof performance, anti-mold performance, safety performance and size stability of the ceramic wood are guaranteed, and therefore the ceramic wood can be directly used on the premise that coating of a coat is notconducted; and when the surface of the ceramic wood is old-fashioned, the performance of the ceramic wood is not influenced after grinding.

The invention provides a slow-release quenching agent for threaded steel to prevent and slow down the corrosion of threaded steel in the atmosphere. A slow-release quenching agent for threaded steel provided by the invention comprises the following components in parts by mass: 2-5 parts of sodium sulfate, 4-6 parts of sodium hydroxide, 1-2 parts of starch, and 5-7 parts of sodium bicarbonate 6-8 parts of sodium phenylacetate, 5-8 parts of alum, and 60-70 parts of water. The invention also provides a preparation method of the slow-release quenching agent for rebar. The slow-release quenching agent for rebars of the invention can effectively prevent and slow down the corrosion of rebars in the atmosphere.

The invention provides a disposal method of sodium phenylacetate deesterification liquid generated by cracking a penicillin G potassium salt crystallization mother liquor and belongs to the technicalfield of pharmaceutical wastewater disposal. The method comprises the steps of mixing a sodium phenylacetate deesterification liquid and active carbon, removing a penicillin degradation product, and conducting filtering to obtain a predisposed sodium phenylacetate deesterification liquid; carrying out primary dialysis on the predisposed sodium phenylacetate deesterification liquid to obtain a primary dialysate and a primary concentrated liquid, wherein the cut-off molecular weight of a dialysis membrane used for the primary dialysis is 6,000-10,000 Da; performing secondary dialysis on the primary dialysate to obtain a secondary dialysate and a secondary concentrated liquid, wherein the cut-off molecular weight of a dialysis membrane used for secondary dialysis is 1,000-4,000 Da; concentrating the secondary dialysate and returning the secondary dialysate to a penicillin fermentation working section. According to the disposal method, there is no need to add hydrogen peroxide or conduct crystallization and crystallization remelting, the amount of generated waste liquid is small, and the energy consumption is low.

The invention relates to a method for recovering phenylacetic acid from waste liquid in preparation of 6-aminopenicillanic acid by an enzymic method. The method comprises the following steps: 1) using toluene to extract phenylacetic acid; 2) preparing a sodium phenylacetate aqueous solution with little impurity; and 3) using macroreticular resin for recovering phenylacetic acid from a water phase containing low-concentration phenylacetic acid. According to the invention, toluene is extracted from waste liquid in preparation of 6-aminopenicillanic acid by the enzymic method, a toluene phase containing phenylacetic acid and a water phase containing low-concentration phenylacetic acid are obtained; the toluene phase containing phenylacetic acid is extracted through alkali lye to obtain the sodium phenylacetate aqueous solution with high quality, the sodium phenylacetate aqueous solution can be directly used for producing penicillin through fermentation; the water phase containing low-concentration phenylacetic acid is pretreated for recovering sodium sulfate, macroreticular resin is used for absorbing phenylacetic acid for recovery, the low concentration water after adsorption can be directly discharged, zero discharge of phenylacetic acid can be almost realized, win-win of economy and environmental protection can be achieved, the by-product sodium sulfate can be used for fermentation, and also has economic benefit.

The invention relates to an additive for monocrystalline silicon texturing liquid. The components of the additive include polyvinylpyrrolidone (PVP), diol, benzene-containing organic acid salt, sodium silicate and deionized water. Among them, PVP is a mixture of one or more of PVP‑K12, PVP‑K15, PVP‑K17, PVP‑K25, PVP‑K30, and the weight ratio to water is 0.2‑1.0:100; A mixture of one or more of ethylene glycol, triethylene glycol, tetraethylene glycol, dipropylene glycol and tripropylene glycol, with a weight ratio of 1.0‑3.0:100 to water; containing benzene Organic acid salt is a mixture of one or more of sodium benzoate, potassium benzoate, sodium phenylacetate, sodium terephthalate and sodium isophthalate, with a weight ratio of 0.1‑1.0:100 to water; sodium silicate and water The weight ratio is 0.1‑1.0:100. The formula of the monocrystalline silicon surface texturing agent is: add 25.0-45.0 mL of NaOH solution with a concentration of 30% by weight in 1 L of deionized water, and add 10.0-20.0 mL of this additive.