32results about How to "Many side effects" patented technology

The application provides a synthesis method of high-purity copper peptide and belongs to the technical field of polypeptide synthesis. The method comprises the following steps: taking o-phthaloylglycyl chloride and L-histidine protected by hexamethyldisilazane as raw materials to react to obtain Pht-Gly-His-OH; protecting Pht-Gly-His-OH by Boc anhydride to obtain Pht-Gly-His(Boc)-OH; activating the carboxyl group of Pht-Gly-His(Boc)-OH to obtain Pht-Gly-His(Boc)-OSu; allowing Pht-Gly-His(Boc)-OSu to react with H-Lys(Boc)-OH to obtain Pht-Gly-His(Boc)-Lys(Boc)-OH; removing the Boc protecting group to obtain Pht-Gly-His-Lys-OH; and finally removing the o-phthaloyl group to obtain GHK.