The invention discloses a system for comprehensive utilization of oil shale destructive distillation and semicoke gasification, which comprises a destructive distillation furnace, an oil shale bin, an oil storage tank, an oil-gas separator, a gas heater, a gasification fuel bin, a combustible gas tank, a heater, a gasification furnace and a conveyer device. According to the invention, by using a process for comprehensive utilization of oil shale destructive distillation and semicoke gasification by using the system, semicoke generated by destructive distillation and powdered oil shale are subjected to gasification reaction to generate combustible gas, a part of combustible gas can be used as a fuel to be introduced into the gas heater to heat a heat carrier gas used in the destructive distillation furnace, high-temperature solid residues generated in the gasification furnace are discharged into a heat exchanger to heat cold water into hot water or vapor. According to the invention, the semicoke generated by oil shale destructive distillation is gasified to be recycled, and thus the addition benefits in an oil shale destructive distillation process is increased, heat pollution and chemical pollution of shale residues are reduced, and energy source utilization rate is improved.