The invention relates to a Chinese herbal medicine combination for treating lymphoma and a preparation method thereof. The combination consists of the following medicinal materials in parts by weight: common selfheal spike, amur corktree bark, weeping forsythiae capsule, plantain seed, Chinese gentian, achyranthes aspera, woodlouse, alga, rhizoma bolbostemmae, rhubarb, safflower, peach seed, earthworm, radix salviae miltiorrhizae, aizoon stonecrop herb, rehmannia root, pilose asiabell root, membranous milkvetch root, laciniate begonia herb, indigowoad root, honeysuckle, hemp fruit, rhubarb, kudzuvine root, barbed skullcap herb, Chinese lobelia herb and ladybell root. The invention chooses the Chinese herbal medicines capable of removing toxicity and relieving swelling and pain, promoting blood circulation to remove blood stasis, resolving hard lumps, promoting diuresis to remove toxicity, strengthening the body resistance to eliminate pathogenic factors and enhancing the immune function of the body as materials, the preparation method for traditional Chinese medicines is adopted to prepare decoction, pills or powder, the Chinese herbal medicine combination for treating lymphoma has a quick curative effect in treating prostatic cancer and bladder cancer, the effect is good, and the prostatic cancer and the bladder cancer can be cured in a short term, and cannot recur after being cured; and the statistics of clinical treatment show that the effective rate is 100 percent and that the cure rate is 87 percent.