The invention belongs to the field of chemical engineering and metallurgy, and particularly discloses a method for comprehensively utilizing vanadium and titanium resources of vanadium titano-magnetite. Vanadium slag obtained in the vanadium blowing procedure is returned to the electric furnace melting separation procedure, vanadium is opened from titanium slag, the vanadium extraction path is changed, vanadium-titanium co-extraction is achieved, and the vanadium extraction tailing treatment problem is thoroughly solved. The crushing particle size of the vanadium-containing titanium slag is controlled, fine-particle carbon powder and a binder are added for granulation, ore/carbon contact is enhanced, catalytic chlorination is coupled, and therefore the chlorination reaction temperature is reduced, and the utilization problem of high-calcium magnesium and titanium resources is solved. A vanadium-iron alloy is directly smelted by adding a reducing agent and steel scraps into titanium tetrachloride vanadium removing dry slag, and therefore preparation of a vanadium pentoxide intermediate product is omitted, the process is greatly shortened, and the production cost is reduced. The method can realize comprehensive utilization of the vanadium and titanium resources in the vanadium titano-magnetite to respectively obtain titanium tetrachloride and ferrovanadium alloy products, and has the advantages of being high in resource utilization rate, capable of achieving energy conservation and consumption reduction, friendly to environment, high in product added value and the like.