71results about How to "Stimulate the immune system" patented technology

The method and device of the present invention for the treatment of avian influenza and other viruses, bacteria, and infectious agents with ultrasonic waves includes a generator and a transducer to produce ultrasonic waves. The ultrasonic transducer has a specially designed ultrasound tip that is able to radiate ultrasound energy toward the body of the target animal or human at a level higher than a traditional ultrasound tip. The apparatus delivers ultrasonic energy without contacting the target through an air/gas medium or through a spray, or by contacting the target with or without a coupling medium. The ultrasonic waves provide a therapeutic effect such as destroying viruses, bacteria, or other infectious agents, increasing blood flow, or stimulating the immune system, etc; additionally, breathing ability is enhanced through the ultrasonic delivery of a medicament to the target's lungs.

A method for contouring the body by destroying adipose tissue is disclosed. This method can reduce the circumference of the treated area, improve skin contour irregularities and smooth the appearance of the skin surface. The method is also used as a body treatment before and after a liposuction procedure.

The present invention describes using, on a repetitive basis, a non-human colonizing helminth compound, in an amount sufficient to establish a transitory parasitic helminth infection and or to simulate in a parasitic helminth infection, thereby having immunosuppressive effect against benign antigens and or stimulating a regulatory immune response characterized by the production of T helper cells 2 (Th2), T regulatory helper cells (TREG) and certain cytokines, including, but not limited to interleukin 10 (IL-10), as a therapy or prophylaxis of allergy and other IgE-mediated disorders, which are marked by an inappropriate IgE immune response including, but not limited to an aberrant and or enhanced IgE antibody production to benign antigens. The invention presents using helminth compound by administering it in a frequency and amount sufficient to eliminate or ameliorate the inappropriate immune response in an asthmatic and or allergic individual.

The invention relates to a preparation method for an oral protein immune carrier, and belongs to the field of medicines. A single template agent is utilized at a room temperature, a mesoporous silica material is synthesized by adopting a sol-gel method. Mesoporous silica particles loaded with a model drug are prepared by adopting bovine serum albumin (BSA) as the model drug and mesoporous silica as a carrier; and the drug loading capacity is 20-21%. Chitosan (CS) is adsorbed on the surface of the mesoporous silica through the electrostatic interaction, so that the biological adhesiveness of the carrier is improved, and the medicine can be effectively prevented from being damaged by a gastrointestinal tract environment. In addition, positively charged chitosan mesoporous silica drug-loaded composite particles are more easily ingested by cells to induce body immunoreaction.

The invention discloses a method for preparing compound lithospermum ointment. The method mainly comprises the following steps that raw materials are prepared and smashed by a smashing machine and screened, so that raw material powder is obtained; the obtained raw material powder and vegetable oil are mixed and after ultrasonic wave extraction is conducted at a certain temperature and time, a solid-liquid mixture A is obtained and placed in a sealable container to be heated according to a warm maceration method; the solid-liquid mixture A obtained after heating is sent to a stirring device with prepared aromatic plant extract liquor through a filtering device, so that the solid-liquid mixture A and the aromatic plant extract liquor are stirred and mixed, and therefore mixed liquid B is obtained; prepared bee wax is heated and fused at the temperature of 65 DEG C to 75 DEG C, the mixed liquid B is added to the fused bee wax, the mixture is cooled and concentrated, and therefore the finished compound lithospermum ointment is obtained. The prepared compound lithospermum ointment is prepared through traditional Chinese medicine and the aromatic plant extract liquor and has the effects of detoxification, inflammation diminishing, acne treatment, skin moistening, sterilization, tissue regeneration promotion, scar removal, mosquito bite resistance and the like.

The invention relates to the use of surfactant mixtures, comprising (a) anionic and/or nonionic surfactants and (b) water soluble beta-(1,3) glucans, which are substantially free of beta-(1,6) links. Said mixtures are used to produce oral hygiene and dental hygiene products in particulars, toothpastes. The preparations are characterized in that the mucous membranes in the mouth have a particularly high degree of tolerability with regard thereto, by exhibiting exceptional foaming properties and a stable distribution of the abrasive substances.

A pharmaceutical composition comprising proton pump inhibitors and prebiotics is proposed for the treatment of gastric and duodenal ulcer, this allowing effective ulcer treatment and eradication of H. pylori from the gastric and duodenal mucosa to be carried out without using wide-spectrum antibiotics. The comprehensive treatment of ulcer disease associated with a helicobaterial infection using a pharmaceutical composition of a PPI and a prebiotic makes it possible, in conditions of an elevated pH of the stomach contents, actively to stimulate the growth of lactobacilli in the upper sections of the gastrointestinal tract, including the duodenum, and substantially to increase the titre of lactobacilli, which are antagonists of H. pylori, which greatly improves the effectiveness of the ulcer treatment.; The high clinical effectiveness and safety resulting from the synergistic action of the proton pump inhibitor and the prebiotic in the upper sections of the gastrointestinal tract, the absence of side effects and recurrences, and also the level of compliance to the combined treatment provided by the claimed pharmaceutical composition indicate that the proposed formulation is a promising new means for the treatment of gastric and duodenal ulcer. Use of the claimed composition dramatically reduces the number of recurrences of the illness.

The invention relates to a preparation method of APP (Actinobacillus Pleuropneumoniae) OMVs (Outer Membrane Vesicles) and a vaccine of the APP OMVs, and belongs to the technical field of biology. The preparation method comprises the steps of culturing APP shope strains in vitro by using a culture medium which is in iron ion limit, obtaining acellular cultural supernatant after carrying out centrifugation and 0.22-[mu]m filtration treatment, and preparing the OMVs released by germs through ultracentrifugation, wherein the observation through a transmission electron microscope shows that the diameter of most OMVs is 50 to 100 nm, the OMVs are used as subunit vaccines to carry out secondary intranasal immunization on a mouse, the weight of the OMV immune mouse is increased for a long time, and the visual forms of lungs have no obvious difference from a PBS (Phosphate Buffer Saline) immune group. Meanwhile, an experiment shows that the OMVs are efficient immune stimulants, not only can high-level IgG (Immunoglobulin G) be stimulated to be generated by mouse sera, but also high-level IgA (Immunoglobulin A) can be generated in mouse lungs, mucosal immunity of the mouse lungs is effectively stimulated, and a better application prospect of using the OMVs as the subunit vaccines is expressed.

The invention relates to a plant growth modifier, and belongs to the technical field of agriculture. The modifier is prepared from, by weight, 55-70 parts of chitosan, 0.05-0.15 part of plant cytokinin, 12-23 parts of tea saponin, 15-28 parts of bittern, 15-22 parts of humic acid, 10-18 parts of cortex meliae, 10-18 parts of sophorae flavescens, 5-12 parts of radix puerariae, 0.5-3 parts of gibberellin, 3-9 parts of medical stone powder and 5-12 parts of volcanic rock powder. The plant growth modifier has a scientific formula, and can effectively regulate the process of growth and developmentof crops so that yield stabilizing and increasing, quality improving, crop resistance enhancing and other effects can be achieved.

The invention discloses a preparation method for yak yoghourt. The yak yoghurt comprises the following raw materials by weight: 120-180 parts of honey, yak milk which is added to 1,000 parts and 4*107-2*108 CFU/ml lactic acid bacteria fermentation liquid. According to the invention, abundant short-chain fatty acid contained in the yak yoghourt prepared by the preparation method enters digestive tract and can promote intestinal motility and the mass growth of much probiotics bodies inside the intestinal canal, which can effectively change the osmotic pressure inside the intestinal canal and prevent constipation; lactic acid inside the yoghourt can not only change the weak acid substances inside the intestinal canal into weak alkali substances, but also can generate antimicrobial substances; through inhibiting the growth of saprophytes inside the intestinal canal and reducing toxin produced by food spoilage, liver and brain can be free from damages caused by the toxin. Therefore, the yak yoghourt has an excellent health-care function to human bodies.

The invention belongs to the technical field of aquaculture, and specifically discloses a feed additive for shrimps and a preparation method thereof. The feed additive for the shrimps is obtained by mixed fermentation of the following components by the mass percentage: 10-15% of photosynthetic bacteria, 20-30% of bacillus, 20-25% of yeast, 25-35% of lactic acid bacteria, 1-5% of brown sugar, 1-5%of rice bran, 0.5-1.0% of sea salt, and the balance auxiliary materials. The feed additive for the shrimps can play a role in protecting intestinal tracts of animals through microorganisms, improve the immunity of the shrimps, reduce the occurrence of diseases and improve the survival rate; the feed additive for the shrimps can improve the intestinal environment of the animals through microorganisms, increase the number of beneficial bacteria in the intestinal tracts, promote the digestion and absorption of a feed by the animals, reduce the food coefficient, promote the growth of the shrimps,improve the production performance, improves the density of shrimp seedlings, allows the shrimp meat to be fresh and sweet, have no fishy flavor and have complete shape, and can be widely used in thefield of aquaculture.

The invention discloses a decavitamin and fermented Chinese traditional medicinal herb preparation special for postpartum breeding sows. Every 1000 parts of Decavitamin and fermented Chinese traditional medicinal herb preparation special for the postpartum breeding sows comprises, by weight, 98.7-125.5 parts of decavitamin, 10-15 parts of compound amino acid, 95-120 parts of polysaccharide and 752.8-676.5 parts of fermented composite fine powder. The decavitamin and fermented Chinese traditional medicinal herb preparation special for the postpartum breeding sows can rapidly supplement the needed nutrients for the postpartum breeding sows, enhance the immunity of the sows and improve stress resistance and the disease resistance. The invention also aims to provide a preparing method and an application of the decavitamin and fermented Chinese traditional medicinal herb preparation.

The invention discloses a traditional Chinese medicine for treating lupus sebaceous. The traditional Chinese medicine is characterized by being prepared from the following raw materials according to a certain ratio: radix codonopsitis, ginseng, salvia miltiorrhiza, astragalus root, rhizoma coptidis, rhizoma polygonati, caulis spatholobi, caulis lonicerae, caulis trachelospermi, cornu bubali, cornu saigae, tuckahoe, atractylis ovata, oldenlandia diffusa, forsythia, prepared nux vomica, liquorice, eclipta alba, angelica, lithospermum, gardenia, cortex lycii radicis, yam, dipsacus root, southernwood, alisma orientale, medlar, fructus ligustri lucidi, achyranthes root, dandelion, bezoar and leech. The traditional Chinese medicine has the characteristics that the starting point is to condition the physiological function of a human body; and the traditional Chinese medicine has good treatment effect and no toxic and side effect, and can treat both principal and secondary aspects of diseases.

The invention provides a tilapia culture method, which mainly comprises the steps of preparing a pond, breeding fish fries, culturing and harvesting adult fish, wherein during a culturing process, a compound feed is fed twice a day, the feeding volume is 2 to 3 percent of the total weight of fishes, and the compound feed is prepared from 90 to 100 parts of basic fish feed, 1 to 8 parts of Chinese herbal medicine and 2 to 6 parts of probiotics. According to the tilapia culture method provided by the invention, the tilapia fries are started to be cultured in the season with mild temperature, and the feed added with the Chinese herbal medicine and the probiotics is fed, so that the tilapia fries grow quickly; the growth and propagation of pathogenic microorganisms can be inhibited, so that a fish body has a favorable digestion inner environment, tilapia can better digest and absorb nutrition components contained in the feed, and the feed conversion rate is improved; an immune system of the tilapia can be stimulated, so that the disease resistance of the fish body is improved; the probiotics can provide an acidic environment during a metabolic process, so that the propagation of the pathogenic microorganisms is inhibited; the meat quality of the tilapia can also be further improved.

The invention discloses an active polypeptide with an antagonistic chemotactic factor receptor CCR5, which has an amino acid sequence in SEQ ID NO:1 or an amino acid sequence obtained by carrying out deletion, addition, insertion and substitution of one or more amino acid residues on the amino acid sequence in SEQ ID NO:1. The invention also discloses a preparation method of the polypeptide, which comprises the following steps of: searching related protein sequences in a database; carrying out multiple alignment comparative analysis to screen out a highly conservative region for combination of a vMIP-II receptor; eliminating interference of unrelated residues through analysis simulation means; determining a target peptide sequence; synthetizing the active polypeptide by a solid-phase synthesis method; and finally testing the bioactivity of the polypeptide. The polypeptide can be used as a CCR5 receptor antagonist for the development of an anti-inflammatory drug, can be used as a lead drug for treating AIDS (Acquired Immune Deficiency Syndrome) and can also be used as a medicament with the immune regulation effect or a medicament for improving the functions of an immune system of an organism.

The invention relates to the technical field of molecular biology, in particular to a codon-optimized peste des petits ruminants virus F gene nucleic acid vaccine. The codon optimization gene sequencegives consideration to the codon use preference of mammalian cells, and a sequence is shown as SEQ ID NO. 2. According to the peste des petits ruminants virus F gene nucleic acid vaccine, after signal peptide at the 5'end of an F gene is removed, the remaining sequence is optimized through codons, the 5 'end is connected with an encephalitis B virus signal peptide sequence, and finally the sequence is inserted into an eukaryotic expression vector. The nucleic acid vaccine effectively stimulates an immune system after immunizing a mouse, generates a neutralizing antibody and reflects good immunogenicity.

The invention discloses composite probiotics for the prevention and adjuvant therapy of cancers and a preparation method thereof. The composite probiotics for the prevention and adjuvant therapy of the cancers are prepared from the following raw materials: mixed bacterial liquid, fructooligosaccharides, coenzyme Q10, glucose, table salt and demineralized water. The preparation method comprises the following steps of: adding the mixed bacterial liquid, the fructooligosaccharides, the coenzyme Q10, the glucose, the table salt and the demineralized water according to a ratio; fermenting at the temperature of between 25 and 30 DEG C for 350 to 370 hours; and cooling to the temperature of between 18 and 22 DEG C, fermenting for 10 to 14 hours again, discharging the bacterial liquid and packaging to form a finished product. Due to the adoption of the technical scheme, compared with the prior art, the composite probiotics for the prevention and adjuvant therapy of the cancers have the advantages of high activity and stability, quick response, no side effect and low cost.

The invention relates to a biological antidiarrheal agent for pigs and a preparation method thereof and belongs to the technical field of animal healthcare products. The preparation method includes: selecting alkaline protease produced by fermenting Bacillus licheniformis CGMCC No.6102, brewer's yeast CGMCC No.11355, Bacillus subtilis CGMCC No.6101 and Bacillus licheniformis CGMCC No.11353, separated from a scavenger intestinal tract, which are collected strains, as main ingredients, wherein the Bacillus licheniformis DE is 15-30 billion cfu/g, the Bacillus subtilis K018 is 20-40 billion cfu/g, the brewer's yeast XDN-1188 is 5-15 billion cuf/g, nano montmorillonite is 200-300mg/g, the alkaline protease is 50-150U/g, and the biological antidiarrheal agent is prepared by taking glucose as a vector. The biological antidiarrheal agent can be used for daily breeding of pig industry, can be used as a raw material of feed and has quick treatment effect on piglet diarrhea.

The invention provides a recombinant expression of shrimp antibacterial peptide in probiotic bacteria and an application thereof, which comprises the clone of a shrimp antibacterial peptide gene, the construction of the recombinant carrier of the shrimp antibacterial peptide gene, the conversion and the screening of the recombinant carrier of the shrimp antibacterial peptide gene, the engineering bacteria of the fermentation culture expressed antibacterial peptide, and the verification and the purification of an expression product. The invention also provides the application of recombining probiotic bacteria with the shrimp antibacterial peptide gene. The probiotic bacteria which is used for aquaculture feed, in particular to feed chiefly used for shrimps. The recombinant probiotic bacteria can continually propagate in an organism body, is expressed continually within a certain period, is provided for the antibacterial peptide of the organism body, and has good specificity and validity.

The invention discloses a special multivitamin immunopolysaccharide microemulsion preparation for waterfowl. Each 1050 parts of the special multivitamin immunopolysaccharide microemulsion preparation for the waterfowl by weight comprises a traditional Chinese medicinal extract, 51.11-102.52 parts of multivitamin, 25.5-51.5 parts of polysaccharide and 12.5-25 parts of sunflower seed oil by weight, wherein the traditional Chinese medicinal extract is obtained by performing alcohol extraction on the following traditional Chinese medicinal raw materials in parts by weight: 200-250 parts of honeysuckle, 350-400 parts of radix bupleuri, 400-450 parts of indigowoad leaf, 150-200 parts of rheum officinale, 100-150 parts of motherwort, 100-150 parts of radix gentianae and 60-80 parts of liquorice. The invention aims to provide the special multivitamin immunopolysaccharide microemulsion preparation for the waterfowl, which can quickly supplement nutrition, resist diseases and promote growth. The invention also aims to provide a preparation method and specific application of the special multivitamin immunopolysaccharide microemulsion preparation for the waterfowl.

The invention relates to the technical field of culturing, in particular to a mixing high-yield cultivation method of mystus guttatus. The method comprises the steps that a piece of land with convenient ventilation and drainage facing the sun is selected as a culturing pond, before the mystus guttatus is put into the pond, disinfection is conducted by using quick lime, and insolation is conducted;12-15 mystus guttatus are put in each square meter, and healthy fry of grass carp, tilapia mossambica and aristichthys nobilis are put into the culturing pond at the same time; the feed for the mystus guttatus comprises icy fresh fish and nutritious feed, and the mass ratio of the icy fresh fish to the nutritious feed is 1-5:6-7; the quick lime is periodically used for sterilizing the culturing pond, and photosynthetic bacterium is periodically added to the culturing pond. By means of the method, the survival rate and growing speed of the mystus guttatus can be effectively improved.

The invention discloses a traditional Chinese herbal medicine feed additive for preventing bacillary enteritis of brachymystax lenok and application of the traditional Chinese herbal medicine feed additive. The traditional Chinese herbal medicine feed additive comprises the following components in parts by weight: 16-20 parts of shepherd's purse, 15-18 parts of isatis roots, 13-18 parts of prepared rehmannia roots, 15-20 parts of Chinese violet, 10-13 parts of vervain, 8-12 parts of wild chrysanthemum flos, 10-13 parts of licorice roots, 8-13 parts of senecio scandens, 3-6 parts of equisetum hyemale and 5-8 parts of flower of operculate cleistocalyx. The traditional Chinese herbal medicine feed additive has the beneficial effects that the additive is a good 'green' medicinal additive, can be completely degraded, is capable of killing pathogene of bacillary enteritis, achieving the purpose of preventing bacillary enteritis of the brachymystax lenok, meanwhile stimulating the immunity system of the brachymystax lenok and improving the immunity of the brachymystax lenok; feed with the additive needs no other antibiotic medicine, so that accumulation of antibiotics in bodies of the brachymystax lenok is reduced, and thus requirements of modern people on foods are met.

The present invention discloses cat food with digestion-helping and appetite-stimulating effects. The cat food comprises the following raw materials in parts by weight: 80-120 parts of wheat flour, 20-50 parts of corn flour, 3-6 parts of apple juice, 3-6 parts of malt, 3-6 parts of probiotics, 5-11 parts of Chinese yam powder, 5-11 parts of sweet wormwood herb, 3-5 parts of poria cocos, 3-5 partsof chicken's gizzard-membrane, 10-15 parts of bananas, 1-3 parts of taurine, 3-5 parts of licorice, 3-5 parts of apricot kernels, 5-9 parts of kelp, 4-8 parts of dried tangerine peels, 5-9 parts of haws, 3-7 parts of nostoc flagelliforme, 2-6 parts of tea polyphenols, 3-7 parts of hazelnut kernels, 4-8 parts of hedychium spicatum seeds, 2-6 parts of thunbergia fragrans stem leaves, 5-8 parts of vegetable oil, 1-4 parts of edible salt and 3-6 parts of honey. The cat food is reasonable in design, proper in method, good in the appetite-stimulating effect and suitable for promotion.

This invention includes methods for treating conditions with pharmaceutical compositions that comprise glycosylated interferon alpha. Pharmaceutical compositions that can be employed in the present invention include glycosylated interferon alpha 2 species in combination with pharmaceutical carriers, pharmaceutical excipients and/or other agents.