The invention relates to a method for preparing a sepiolite-tetraacicular zinc oxide whisker composite material. Sepiolite has extremely strong adsorption performance and good dispersion performance, and can be used as the carrier and skeleton of the tetraacicular zinc oxide whiskers in the present invention, and the respective performances do not affect each other. The preparation method is as follows: dissolve sepiolite in ethanol, methanol or hydrogen peroxide, stir evenly, separate and dry to obtain sepiolite powder; mix with zinc powder, dissolve in distilled water, ethanol, methanol, hydrogen peroxide, stir and mix uniformly; The separated solid mixture is dried in an oven; the dried powder is calcined in a high-temperature furnace to obtain a sepiolite-tetraacicular zinc oxide whisker composite material. The composite material prepared by the present invention has properties such as wear resistance, reinforcement, shock absorption, anti-skid, noise reduction, anti-aging, antistatic, antibacterial, etc., and can be widely used in coatings, antibacterial materials, antistatic materials, antifriction and antiwear, etc. Among the materials, the operation process is simple, and the cost performance is high.