36 results about "Pentylone" patented technology

The invention relates to a method for preparing ethoxy quinoline and belongs to the field of fodder and food. The preparation of the ethoxy quinoline is divided into two steps, namely the preparation of midbody 4-methyl-3-penten-2-ketone and the preparation of a finished product ethoxy quinoline. The method comprises the steps that firstly acetone is transformed into the midbody 4-methyl-3-penten-2-ketone, the potential safety hazards to an operator due to the fact that in the reaction process, the acetone is not reacted completely and volatilized under heating are prevented, and in the transformation process of the 4-methyl-3-penten-2-ketone, by using a catalyst, namely 4%-6% of Mg2+mesoporous molecular sieve, the high-purity 4-methyl-3-penten-2-ketone midbody can be obtained; methylbenzene serves as solvent as well as a water-carrying agent, 'azeotropy' is conducted through the methylbenzene and water generated in reaction, water can be separated, so that the reaction is conducted toward the positive reaction direction, meanwhile, by adding the methylbenzene solvent, an 'inert' solvent gas environment is formed inside a reaction tank, and oxidation of materials is avoided; by means of the combined action of the methylbenzene and toluenesulfonic acid, the produced ethoxy quinoline can reach the standards of feed grade ethoxy quinoline.

The invention discloses a self-cleaning flame-retardant corrosion-resistant fluorine-silicon powder coating. The coating is prepared from the following components in parts by weight: 50-60 parts of afilm-forming copolymer, 4-8 parts of amino-terminated hyperbranched compound quaternary ammonium salt, 1-3 parts of lignosulfonic acid, 0.1-0.2 part of phosphorus pentoxide, 3-7 parts of a functionalaid, 10-15 parts of an inorganic filler and 1-3 parts of rare earth fluoride nanofibers, wherein the film-forming copolymer is prepared from 2-trimethylsiloxy-1,1,1,5,5,5-hexafluoro-2-penten-4-one, (E)-4-(2-cyano-3-ethoxy-3-oxo-1-propenyl)phenylboronic acid pinacol ester, trimethyl 4-phosphonobutenoate, N-hydroxysuccinimide methacrylate and 1,3-bis(oxiranylmethyl)-5-(2-propenyl)1,3,5-triazinyl-2,4,6(1H,3H,5H)-trione through a free radical polymerization reaction. The powder coating disclosed by the invention is remarkable in self-cleaning effect, good in performance stability, corrosion resistance, weather resistance, wear resistance, film-forming property and flame retardance, excellent in bonding property with a base material, superior in comprehensive performance, and safe and environment-friendly to use.

The invention discloses a method for continuous production of 3-methyl-3-penten-2-one in a micro-channel reactor and belongs to the technical field of organic synthesis processes. The method comprisesthe following specific steps: mixing 2-butanone with an ionic liquid [Ps-min]HSO4; simultaneously pumping a raw material acetaldehyde and a mixed solution of 2-butanone and a catalyst into a preheating module through metering pumps respectively, and introducing the components into an integral micro-channel mixer; performing uniform mixing, further introducing the components into a micro-channel reactor, and performing a reaction; and introducing the components into a cooling module, performing sample, and performing separation so as to obtain 3-methyl-3-penten-2-one. By adopting the method, aproduct can be efficiently and rapidly synthesized; the ionic liquid [Ps-min]HSO4 replaces a conventional inorganic acid to be used as a catalyst of the reaction, the reaction condition is mild, andthe product yield is high; meanwhile, the catalyst is easily separated from reaction products, the acid-base neutralization process of a conventional process is avoided, production of wastewater can be reduced, and the environment can be protected.

The invention relates to a preparation method of paclobutrazol. The preparation method uses a compound represented by formula (I) as a raw material to carry out catalytic hydrogenation reaction in the presence of hydrogen and a catalyst, thereby preparing paclobutrazol. Wherein, the chemical name of the compound represented by formula (I) is 1-(4-chlorophenyl)-4,4-dimethyl-2-[1,2,4-triazolyl]-1-pentene- 3-ketone. The process of the invention is relatively safe, simple in operation, low in cost, less in three wastes, higher in paclobutrazol content and yield, and suitable for industrial production.

The present application provides a process for the high yield production of methylpentenone (MPO) in a continuous mode by reacting an excess amount of methyl ethyl ketone (MEK) with acetaldehyde in the presence of a cation exchange resin catalyst in a fixed bed reactor having a plurality of sidewall injection ports, wherein acetaldehyde is injected from a plurality of sidewall injection ports of the reactor. The method also effectively reduces the complete consumption of the catalyst in the reaction process.

The invention discloses a (Z)-4-difluoroalkyl-5-sulfanyl-4-pentenone derivative and a preparation method thereof. The preparation method comprises following steps: an alkyne thioether with a structureshown in formula II, monobromo difluoroacetate, fac-Ir(ppy)3, an alkali and a solvent are mixed, a reaction system is formed under blue light irradiation, and the (Z)-4-difluoroalkyl-5-sulfanyl-4-pentenone derivative with a structure shown in formula I is obtained through aftertreatment. According to the invention, the addition-hydrogen migration-noncyclization cascade reaction of free radicalson non-terminal alkyne is realized for the first time, and the stereoselective synthesis of the (Z)-4-difluoroalkyl-5-sulfanyl-4-pentenone derivative is realized in one step. The reaction conditions are mild, the substrate application range is wide, the reaction yield is good, the operation is simple, and a new way is provided for synthesis of fluorine-containing pentenone compounds.

The invention discloses a derivative of (Z)-4-trifluoromethyl-5-sulfanyl-4-pentenone and a preparation method thereof. (Trifluoromethyl) dibenzothiophenium trifluoromethanesulfonate, three (2,2 bipyridyl) ruthenium dichloride, alkali and solvent are added and mixed, and a reaction system is formed under blue light irradiation. After the reaction is completed, the Post-treatment to obtain a (Z)-4-trifluoromethyl-5-sulfanyl-4-pentenone derivative of the structure of formula I. The invention realizes the stereoselective synthesis of a (Z)-4-trifluoromethyl-5-sulfanyl-4-pentenone derivative in one step. The reaction condition is mild, the substrate has a wide application range, the reaction yield is good, and the operation is simple, which provides a new way for the synthesis of compounds containing trifluoromethyl pentenoids.

The invention discloses a 1-phenyl-4-penten-1-one derivative represented by formula (1) and a synthesis method thereof, using diazo compounds, allyl alcohol derivatives and alkyl alcohols as raw materials, The 1-phenyl-4-penten-1-one derivative is obtained by using metal palladium, metal rhodium and an organic phosphine ligand as catalysts in an organic solvent through one-step reaction. The synthesis method of the 1-phenyl-4-pentene-1-ketone derivative of the present invention has the advantages of high atom economy, high regioselectivity, low catalyst consumption, simple and safe operation, and the obtained 1-phenyl-4 ‑Penten‑1‑one derivatives are important chemical and pharmaceutical intermediates.

The invention discloses a synthesis method of cis-jasmone, which specifically comprises the following steps: carrying out Grignard reaction on 1, 4-dichlorobutene and methylmagnesium chloride in a THF (tetrahydrofuran) medium to obtain 1-chloro-2-pentene; the method comprises the following steps: carrying out cyclization reaction on 2, 5-hexanedione in a dibromomethane medium under a strong alkaline condition to obtain 3-methyl-2-cyclopentene-1-ketone. According to the method, 1-chloro-2-pentene and 3-methyl-2-cyclopentene-1-ketone are subjected to an addition / elimination reaction in an ethanol medium under an alkaline condition, and cis-jasmonone is obtained. Compared with other synthesis methods, the method has the advantages of short process route, high reaction selectivity and conversion rate, high product yield, low cost and the like.

The invention discloses a preparation method of 2,2-dimethyl-5-(4-chlorobenzyl) cyclopentanone, which uses p-chlorobenzaldehyde and 2,2-dimethyl-4-cyclopentanone En-1-ketone, that is, the compound of formula I, is used as the initial raw material. After aldol condensation, hydrogenation, hydroxyl removal and further hydrogenation, the compound of formula V is obtained, which is the intermediate 2,2-dimethyl-5 of metconazole ‑(4‑chlorobenzyl) cyclopentanone, compared with the prior art, the inventive method avoids the use of high-risk compound sodium hydride, avoids operations such as highly toxic methylation, and the reaction is moderate and easy to control. The target product 2, The 2-dimethyl-5-(4-chlorobenzyl) cyclopentanone has a purity greater than 95%, a total yield of over 65%, meets the requirements of green chemical industry, and is suitable for industrial production.

The invention discloses a (1S,4aS,8aS)-Decahydro-5,5,8a-trimethyl-2-methylene-1-naphthaleneacetaldehyde-based spice and a preparation process thereof. According to the method, butanone and acetaldehyde are used as raw materials for aldehyde ketone condensation; then, myrcene and 3-methyl-3-pentene-2-one are used for carrying out diene addition; and finally, a diene addition product is cyclizedto obtain the product. A catalyst is prepared in the cyclization process; the catalyst is prepared by the following steps: polymerizing a styrene micromonomer to prepare a first matrix; sulfonating the first matrix under the action of sulfuric acid to obtain a second matrix; and soaking the second matrix in a ferric chloride solution to produce the catalyst. The catalyst is a cation exchange resincatalyst, compared with the prior art, phosphoric acid is not used for catalysis, environmental pollution is prevented, metal iron ions are loaded on the cation exchange resin, sulfonic acid acid acid groups on the surface of the catalyst can be combined with the iron ions through complexation, then a stronger acid center is formed, and the preparation efficiency of the (1S,4aS,8aS)-Decahydro-5,5,8a-trimethyl-2-methylene-1-naphthaleneacetaldehyde is greatly improved.

The invention belongs to the technical field of fine chemistry, and provides a preparation method of 4-furfurylthiopentanone-2, which specifically comprises the following steps: adding raw material chloroacetone into a toluene solution of triphenylphosphine or adding triethyl phosphite , the temperature is raised and refluxed to obtain a phosphorus salt; the obtained phosphorus salt is dissolved in an organic solvent, a strong base is added, and stirred for 2 to 3 hours, the reaction is completed, and phosphorus ylide is obtained; Stir until the reaction is completed to obtain 3-pentene-2-ketone; piperidine is added to 3-pentene-2-ketone, the dichloromethane solution of furfuryl mercaptan is added dropwise, and the temperature of the system is controlled to be 35~ 40° C., after the dropwise addition, the mixture was stirred until the reaction was completed to obtain the product 4-furfurylthiopentanone-2. The invention solves the problems in the prior art that the synthesis route of 4-furfuryl pentanone-2 is high in danger, high in cost and unsuitable for industrial production.

The invention discloses an environment-friendly conformal paint, which is characterized in that it comprises the following raw materials in parts by weight: 3-6 parts of octaaminophenyl POSS, 10-15 parts of epoxy-terminated polyurethane, 3-azabicyclo [3,1,0]Hexane-2-carboxylic acid modified amino-terminated polyurethane 20-30 parts, 2-vinyl-3H-4-quinazolone / 2-(5-chloro-2H-benzothiazole- 2-yl)-6-(1,1-dimethylethyl)-4-vinylphenol / 2-trimethylsiloxy-1,1,1,5,5,5-hexafluoro-2- Pentene-4-ketone / 3-(2-propenylselenyl)-L-alanine / glycidyl acrylate copolymer 15-25 parts, polyethylene glycol dicarboxylic acid modified nano-zinc oxide 3-6 3-5 parts of driers, 1-3 parts of defoamers, 0.5-1.5 parts of antistatic additives, 25-35 parts of isopropanol, and 0.5-1.5 parts of emulsifiers. The invention also discloses a preparation method of the environment-friendly three anti-paint. The environment-friendly three-proof paint disclosed by the invention has better overall performance, better moisture-proof, anti-fog, and mildew-proof effects, better electrical insulation performance, wear resistance, high temperature resistance, solvent resistance and chemical resistance, and better adhesion. Higher, safe and environmentally friendly in the process of preparation and use.

The present invention provides sila-β-dynasty ketone represented by formula I, that is, 1-(3-sila-3,3-dimethylcyclohex-1-enyl)pent-4-en-1- ketone. This compound is a fragrance compound with a strong pineapple aroma. The invention adopts the intercalation and ring expansion reaction of terminal alkyne to silacyclobutane under the catalysis of palladium to prepare the sila-beta-dynasone with high yield. The method has easy-to-obtain raw materials, wide application range, high separation yield, simple experimental equipment and operation, and is convenient for industrialization.

The invention discloses a 4-methyl-4-phenylcyclopentenone compound and a preparation method thereof. The present invention mixes 0.18~0.22mmol methyl acetylene ketone, 0.38~0.42mmol p-toluenesulfonyl hydrazone, 0.018~0.022mmol copper hydroxide and 0.8~1.2mmol lithium methoxide under the condition of inert gas atmosphere and stirring. Add 3-5mL solvent toluene and 3.5-3.8μL water to the solution to obtain a reaction solution, heat up to 95-105°C and react for 12-24 hours; after the reaction is completed, the insoluble solids are removed by filtration, and the resulting solution is distilled under reduced pressure, concentrated and separated to obtain Target product 4,4-disubstituted cyclopentenone. The process conditions required by the preparation method of the present invention are simple, the reaction conditions are mild, and 4,4-disubstituted cyclopentenone derivatives can be effectively obtained, and the reaction has good substrate applicability and functional group tolerance; at the same time, the present invention is For the first time, 4-methyl-4-phenylcyclopentenone was prepared by intercalation and cleavage of carbon-carbon triple bond.

The invention discloses a self-cleaning, flame-retardant and corrosion-resistant fluorosilicon powder coating, which comprises the following components in parts by weight: 50-60 parts of film-forming copolymer, 4-8 parts of quaternary ammonium salt of amino-terminated hyperbranched compound , 1-3 parts of lignosulfonic acid, 0.1-0.2 parts of phosphorus pentoxide, 3-7 parts of functional additives, 10-15 parts of inorganic fillers, 1-3 parts of rare earth fluoride nanofibers; the film-forming copolymer is 2-trimethylsiloxy-1,1,1,5,5,5-hexafluoro-2-pentene-4-one, (E)-4-(2-cyano-3-ethoxy 3-oxo-1-propenyl) pinacol phenylboronate, trimethyl 4-phosphocrotonate, N-hydroxysuccinimidyl methacrylate, 1,3-bis(oxirane (methyl)-5-(2-propenyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione by free-radical copolymerization. The powder coating disclosed by the invention has remarkable self-cleaning effect, good performance stability, corrosion resistance, weather resistance, wear resistance, film forming property, and flame retardancy, good bonding performance with the base material, excellent comprehensive performance, and safe use Environmental friendly.

The invention discloses a new method for synthesizing (1R, 2S)-dihydrojasmonate methyl ester by using an asymmetric Michael addition reaction. In this method, cyclopentanone is used as a starting material, and an aldol condensation reaction occurs with n-valeraldehyde under alkaline conditions to generate 2-pentylidene cyclopentanone 2, and then double bond transposition occurs under acidic conditions to obtain 2 ‑n-Pentyl‑2‑cyclopentenone 3. Then, under the catalysis of chiral amino acid lithium salt, a Michael addition reaction occurs with dimethyl malonate, and after two silica gel column chromatography separations, (1S, 2S)-2-n-pentyl-3-malonate di Methoxycyclopentanone 4. Finally, through hydrolysis and decarboxylation reaction, (1R,2S)-methyl dihydrojasmonate is obtained. The synthesis route of the invention is simple and convenient, the reaction conditions are mild, and the target compound can be prepared by only four steps of reaction.

The invention discloses a method for the continuous production of 3-methyl-3-pentene-2-ketone by reactive distillation. The raw materials are 2-butanone and acetaldehyde, and a novel microspherical polymer ionic liquid P(VB-VS ) HSO 4 As a catalyst, acetaldehyde and 2-butanone undergo an aldol condensation reaction in the reactive distillation tower to generate 3-methyl-3-penten-2-ketone, and then the reaction solution is sent to the vacuum tower for rectification The reactants and products are separated to obtain high-purity 3-methyl-3-penten-2-one. The invention adopts new microspherical polymer ionic liquid instead of the traditional strong acid and strong base as the reaction catalyst, the reaction conditions are mild, the conversion rate and selectivity of acetaldehyde are high, and the acid in the traditional process is also omitted while reducing side reactions. The alkali neutralization process greatly reduces energy loss and waste water treatment, is energy-saving and environmentally friendly, and the excess 2-butanone can continue to be used as a reaction raw material after separation, reducing resource loss.