The invention discloses a processing method of ostrich texture simulated leather. The processing method is characterized by comprising the following steps of flatly spreading a delimed and softened pelt on a pin board, wherein a grain side of the pelt is upward, and a flesh side is in contact with wood screws; afterwards, uniformly brushing a pattern fixing agent on a part, which is convex on thepin board, of the pelt, wherein the pattern fixing agent is at least brushed for 1 time; and after the brushing of the pattern fixing agent is finished, standing for at least 5min, and carrying out acid pickling, tanning, after-tanning wet processing and coating operation according to normal operation, thus obtaining an ostrich texture leather finished product. Distances among wood screws on the pin board are 2cm to 6cm; and the heights at which the wood screws protrude the plane of the pin board are 0.5cm to 3cm. The pattern fixing agent is an aldehyde solution with the pH (potential of Hydrogen) of 8.0 to 9.5; and the aldehyde solution is prepared from any one of formaldehyde with a mass friction of 40%, glutaraldehyde with a mass friction of 50%, modified glutaraldehyde with a mass friction of 45%, acetaldehyde with a mass fiction of 60% or furaldehyde with a mass friction of 50%. The delimed and softened pelt is any one of a cattle hide, a buffalo hide, a dzo hide or a yak hide. The method is simple, low in cost, high in operability, and moreover, easy in style change, and is used for producing ostrich skin pattern simulated leather with different characteristics.