The invention discloses a mildew-resistant and antibacterial multi-fiber blended woven fabric, which is woven by warp and weft through an air-jet loom, and is characterized in that the raw materials of the warp and weft are made of the following raw materials in parts by weight: isotactic Polypropylene 30-36, cinnamaldehyde 3-5, thiourea 1-2, stannous sulfate 0.4-0.8, kaolin 3-6, modal fiber 25-34, milk grass fiber 20-25, elastic cotton fiber 19-26, Coconut carbon fiber 23-28, fluorosilicone resin 7-9, toluene diisocyanate 8-12, butanol 10-14, mulberry white bark 2-4, Scutellaria 3-4, 1-butyl-3-methylimidazole ethyl Salt 80-90, 1-allyl-3-methylimidazolium chloride 100-110, auxiliary agent 4-7, appropriate amount of water; the preparation method of the present invention has simple and convenient procedures, is easy to implement, and can be obtained through reasonable selection of raw materials and scientific preparation. Proportion design, the prepared woven fabric has comprehensive functions; the invention adds a variety of plant fibers and soaks them in Chinese herbal medicines, which not only improves the spinnability and spinning quality of plant fibers, but also improves the technical performance of woven fabrics. It has excellent properties such as mildew and antibacterial, soft touch, moisture absorption and breathability, suction and noise reduction, dust removal and heat insulation.