The invention discloses a surface treatment process of a 6063 aluminum alloy profile, and relates to the related technical field of aluminum alloy profile production and processing. The process comprises the following steps of A, cutting; B, sand blasting, C, oil removing, D, washing, E, alkali washing, F, neutralizing, G, oxidizing, H, hole sealing, I, airing, and J, forming. Compared with a traditional acid etching process, the process has the advantages that pollution is less, aluminum material is more saved, the overall quality of the aluminum material is guaranteed, and the utilization rate of the aluminum material is higher; when the 6063 aluminum alloy is processed through a soaking pool, NaF is added into an alkali etching agent, so that the outer surface of the 6063 aluminum alloycan be effectively sealed, and the problem of uneven corrosion on the outer surface of the 6063 aluminum alloy is solved; and the gluconate is added into the alkali etching agent, through the gluconate, the leveled surface reduction efficiency of the 6063 aluminum alloy can be improved when the 6063 aluminum alloy is soaked and processed, so that the outer surface of the 6063 aluminum alloy is more leveled.