Disclosed are high low-temperature impact toughness thick steel plates for hydrogen-contacting equipment and a production method thereof. The production method includes the steps: firstly, smelting and casting; secondly, heating plate blanks at 1070-1210 DEG C and rolling the plate blanks according to a compression ratio of 2.7-6.4; thirdly, normalizing within an austenitization temperature range; fourthly, accelerated cooling with water for 4-15 minutes; and fifthly, tempering at 700-750 DEG C; and sixthly cooling, wherein the steel plates comprise, in weight percentage, 0.10-0.15% of C, 0.50-0.60% of Si, 0.40-0.60% of Mn, not more than 0.010% of P, not more than 0.003% of S, 1.25-1.50% of Cr, 0.45-0.65% of Mo, 0.08-0.18% of Cu, 0.07-0.17% of Ni, 0.020-0.045% of Al, not more than 0.003% of Sn, not more than 0.003% of Sb, not more than 0.003% of As, 0.0020-0.0070% of N, the balance of Fe and unavoidable impurities, low-pressure section water flow of a pressure quenching machine is 18-38m<3>/min, top-to-bottom water volume ratio of each steel plate is 1:1.0-1.3, and the surface temperature of the steel palate at an outlet of the pressure quenching machine is not more than 120 DEG C.