Patents
Literature
Patsnap Copilot is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Patsnap Copilot

166results about How to "Improve the ability to form" patented technology

Ruthenium complex capable of inhibiting tumor angiogenesis and preparation method and application thereof

The invention belongs to the field of chemical drugs, and discloses a ruthenium complex capable of inhibiting tumor angiogenesis and a preparation method and application thereof. The ruthenium complex provided by the invention has a structure shown in a formula I or II. The preparation method comprises the following steps of: dropwise adding a silver nitrate solution to a sodium salt solution, stirring and reacting, then filtering, washing and vacuum drying a precipitate, and thereby obtaining a ligand O-O; taking ruthenium chloride, L, and lithium chloride to be dissolved in N-, N-dimethyl formamide, heating and refluxing under the protection of argon atmosphere to obtain an intermeidate Ru (L2) Cl22 +; allowing the ligand O-O and the Ru (L2) Cl22 + to be dissolved in an ethanol/water mixed solvent, heating and refluxing to obtain the ruthenium complex shown in the formula I; and allowing the Ru (L2) Cl22 +, 8- hydroxyquinoline, and ammonium acetate to be dissolved in ethanol, and heating and refluxing under the protection of argon atmosphere to obtain the ruthenium complex shown in the formula II. The ruthenium complex has the advantages of good stability, uneasiness in hydrolysis, good solubility, low toxicity, and the ability to inhibit tumor angiogenesis, and is easily absorbed by the human body.
Owner:JINAN UNIVERSITY

Preparation method of cell nutrient solution for promoting hair regeneration

The invention provides a preparation method of a cell nutrient solution for promoting hair regeneration. The preparation method mainly comprises three steps: 1) primary isolation of ADSCs (adipose-derived stem cells); 2) enlarged cultivation of the ADSCs; and 3) induced culture of the ADSCs. The cell nutrient solution prepared by the invention can solve the problem of alopecia from the point of cell regeneration; the ADSCs-conditioned medium (the nutrient solution), in a periodic hair follicle reconstruction process, can activate a stem cell microenvironment of hair follicle and can regulate and control the normal growth of the hair follicle; by conducting low-dose UVB radiation, ADSCs survival, migration and paracrine capacities can be significantly improved, and an angiogenesis capacity and a hair regeneration capacity can be also obviously improved; by cultivating the ADSCs with a fibroblast-conditioned medium, cell survival and metabolism processes in a body environment can be simulated, and the secretion of more cell factors, which are conducive to cell microenvironment regulation and control, from cells can be promoted; and meanwhile, the cell nutrient solution prepared by the method is convenient in cell preparation, broad in source and convenient for clinical popularization, and cells can be derived from fat wastes obtained from clinical liposuction and skin grafts removed in other surgical operations.
Owner:陕西佰瑞衡健康科技有限公司

Nanocrystalline magnetically soft alloy, amorphous magnetically soft alloy and preparation methods of nanocrystalline magnetically soft alloy and amorphous magnetically soft alloy

ActiveCN110670000AImprove high frequency permeabilityImproving the high and high frequency permeability of soft magnetic alloysInorganic material magnetismCrystallization temperatureFerromagnetism
The invention provides a nanocrystalline magnetically soft alloy, an amorphous magnetically soft alloy and preparation methods of the nanocrystalline magnetically soft alloy and the amorphous magnetically soft alloy. The nanocrystalline magnetically soft alloy comprises the compositions of Fe, Cu, Si, B, and Nb, and further comprises at least one element between Mn and Cr, wherein the atomic percentage content of each element at the at least one between the Mn and the Cr is not more than 3.5 at%. The antiferromagnetism of the Mn element and/or the Cr element is utilized, and a heat treatment mode of multi-stage rate annealing is combined, so that the high-frequency magnetic permeability of the magnetically soft alloy is improved, the high-frequency loss of the magnetically soft alloy is reduced, and the high-frequency magnetic performance of the magnetically soft alloy is improved; meanwhile, the crystallization temperature interval is narrower, and the heat treatment temperature interval is wider, so that the high-quality nanocrystalline magnetically soft alloy or the high-quality amorphous magnetically soft alloy are obtained favorably and the preparation cost is reduced; and inaddition, the oxidation resistance of the Mn element and/or the Cr element is further utilized, so that the tolerance of impurities is improved, the surface of an amorphous strip is prevented from being crystallized, the amorphous forming capacity is improved, and the high-quality magnetically soft alloy can be prepared through low-purity commercial raw materials.
Owner:GLOBAL ENERGY INTERCONNECTION RES INST CO LTD +3

Preparation process for improving forming ability of Fe-base amorphous alloys

The invention discloses a preparation process for improving the forming ability of Fe-base amorphous alloys, which belongs to the preparation method of Fe-based amorphous alloys. The process is low in cost, and simple and practicable, and can obviously increase the amorphous forming ability under the condition that the saturation magnetization is not reduced. According to the invention, stripped and blocky Fe-base amorphous alloy samples are respectively prepared by using a single-roll rapid quenching or copper mold casting method. The process specially comprises the following steps: under the protection of argon, adding a microelement into a Fe-base amorphous alloy, melting the obtained object in a reacting furnace in stoichiometric ratio, and rapidly cooling and solidifying the obtained product, so that a Fe-base amorphous alloy with high saturation magnetization and large amorphous forming ability is obtained, wherein the added microelement is a copper element, and the microelement accounts for 0.1-1.0% of the Fe-base amorphous alloy by total atomic percent. The process has the advantages that 1, an adopted Fe-base amorphous alloy preparation technology is simple and practicable, and low in cost; 2, the saturation magnetization is reduced while the amorphous forming ability is increased; and 3, the process is applicable to most of primary-phase non-alpha-Fe Fe-base amorphous alloy systems, thereby promoting the popularization and application of the Fe-base amorphous alloys.
Owner:CHINA UNIV OF MINING & TECH

Ti-Zr-Cu-Be four-element amorphous composite with processing hardening capacity and preparation method thereof

The invention discloses a Ti-Zr-Cu-Be four-element amorphous composite with the processing hardening capacity and a preparation method thereof. The composite is a type of amorphous alloy composite containing a dendritic crystal phase, wherein the dendritic crystal phase is prepared from the chemical components of 59-60 parts of Ti, 38-39 parts of Zr and 1-3 parts of Cu, the volume fraction of the dendritic crystal phase is 5-95%, and an amorphous matrix is prepared from the chemical components of 33-34 parts of Ti, 35-36 parts of Zr, 8-9 parts of Cu and 21-24 parts of Be. The dendritic crystal phase has the deformation-induced Martensite phase transformation characteristic, the composite shows excellent comprehensive mechanical properties of high strength, high plasticity, processing hardening and the like under the actions of tension and compression loads, for example, under the tension load, the processing hardening behavior is remarkable, the plastic deformation capacity is 6-15%, and the strength is 1100-1900 MPa. Meanwhile, by means of Martensite phase transformation, the composite has the super-elastic characteristic under the tension load through cyclic loading, for example, elastic deformation can be 2.7-3%. As for the composite, the chemical composition is simple, the chemical components of the second phase are relatively stable, and structural design and controllable preparation of the composite are facilitated.
Owner:INST OF METAL RESEARCH - CHINESE ACAD OF SCI

Method for preparing rhizoma drynariae/pig bone powder/chitosan compound bracket material

The invention adopts a method for preparing a medicated tissue engineering bracket material by a fully natural material, which overcomes the defects of slower growth of bone tissues at the initial period of implantation and weak synostosis at the initial period in the traditional tissue engineering bracket. The traditional Chinese medicines of rhizoma drynariae and pig bone type hydroxylapatite are introduced into the bracket to obtain a compound tissue engineering bracket material with excellent biological activity. The pig bone type hydroxylapatite is extracted from pig bones, has excellent biological activity and low production cost, is green and innoxious and is pulverized to reach a micron / nano state; the traditional Chinese medicine of the rhizoma drynariae has the functions of promoting the multiplication of osteoblast, accelerating the bone growth, diminishing inflammation and resisting bacteria and is prepared by an effective water extraction solvent method, a pulverization method and a spraying method; and the chitosan is used as a template and is prepared by a vacuum freeze drying method. The porosity of the bracket material is between 45% and 91%, the aperture is adjustable within a range of 40-500mu m, and the compressive strength can reach 0.1-5.6MPa. In the degradation process, the pH value of the bracket is between 6.77 and 7.50.
Owner:JIAMUSI UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products