The invention discloses a
hesperetin derivative containing a thiosemicarbazone structure and application of the
hesperetin derivative, the molecular formula of the compound is C18H19N3O5S, the
biological activity determination result shows that the compound has good anti-oxidation and anti-alpha-
glucosidase activity, the IC50 value of
DPPH scavenging activity is 6.17 mu g / mL, and the activity of the
hesperetin derivative is equivalent to that of a control agent
vitamin C. The hesperetin derivative containing the thiosemicarbazone structure and the application of the hesperetin derivative containing the thiosemicarbazone structure have good anti-oxidation and anti-alpha-
glucosidase activity. The IC50 value of
ABTS clearance activity is 0.04 mu g / mL, and the activity is improved by 200 times compared with that of a control medicament
vitamin E; the IC50 value of the alpha-
glucosidase inhibitory activity is 4.53 [mu] g / mL, which is improved by 51 times compared with the activity of a control agent
acarbose; the
structural formula of the hesperetin derivative containing the thiosemicarbazone structure is shown in the specification.