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6 results about "Indophenol" patented technology

Indophenol is an organic compound with the formula OC₆H₄NC₆H₄OH. It is deep blue dye that is the product of the Berthelot's reaction, a common test for ammonia. The indophenol group, with various substituents in place of OH and various ring substitutions, is found in many dyes used in hair coloring and textiles.

An application of LC-MS / MS in determining the content of indophenol sulfate and p-cresol sulfate in a hemoperfusion device.

This invention relates to the field of medical device testing technology, specifically to the application of LC-MS / MS in determining the content of indophenol sulfate and p-cresol sulfate in a hemoperfusion device. The method includes: mixing plasma and acetonitrile, vortexing and centrifuging, collecting the supernatant, eluting the supernatant through a C18 solid-phase extraction column, collecting the eluent, mixing the eluent with water and filtering to obtain the test solution; performing liquid chromatography and mass spectrometry on the test solution, wherein the mobile phase A of the liquid chromatography is a 3-8 mmol / L gradient concentration ammonium acetate solution containing 0.05% ammonium formate by volume, and the mobile phase B is methanol; S3: calculating the concentrations of indophenol sulfate and p-cresol sulfate in the test solution based on the labeled curve. This invention, through dual purification pretreatment and multi-ion-pair threshold matching technology, can effectively remove more than 95% of interfering protein-binding toxoids. The interference peak response value in blank plasma is less than 5% of the target analyte response value, solving the detection error problem caused by interference in traditional methods.
Owner:GUANGDONG MEDICAL DEVICE QUALITY SUPERVISION & INSPECTION INST

A method for detecting indoxyl sulfate based on surface-enhanced raman spectroscopy

PendingCN122282743ASurface-enhanced Raman spectroscopyRaman microscope
This invention relates to a method for detecting indophenol sulfate based on surface-enhanced Raman spectroscopy. A liquid containing the indophenol sulfate to be detected is mixed with an oxidizing reagent to specifically oxidize the indophenol sulfate to indigo, yielding a mixed solution. This mixed solution is then mixed with gold nanoparticles, and the spectra of the mixed solution are acquired using a confocal Raman microscope. The acquired Raman spectra are baseline-removed to obtain the signal intensity at the target characteristic peak. Based on standard curves for different concentrations of indophenol sulfate and the signal intensity of the sample, the concentration of indophenol sulfate in the test sample is determined. This invention provides clear detection signals, accurate resolution, and a simple operation, enabling rapid and accurate detection of indophenol sulfate concentration in samples (such as serum). It is expected to promote research on the biological mechanisms of indophenol sulfate and its large-scale clinical application.
Owner:SHANGHAI JIAOTONG UNIV

A method for determining the concentrations of indophenol sulfate and p-cresol sulfate in plasma

This invention relates to the field of indophenol sulfate and p-cresol sulfate technology, and particularly to a method for determining the concentrations of indophenol sulfate and p-cresol sulfate in plasma. The method involves pretreating the sample, followed by determination of the concentrations of indophenol sulfate and p-cresol sulfate in the sample using liquid chromatography-mass spectrometry and an internal standard method. The sample includes plasma, and the pretreatment involves protein precipitation. This method exhibits good linearity, a low limit of quantitation, strong anti-interference capabilities, and high precision and accuracy.
Owner:TIHE (HANGZHOU) PHARM TECH SERVICE CO LTD

Photocleavage of indican

PendingUS20260062863A1Dyeing processFermentationPolymer scienceIndican
The present invention concerns the use of light to convert indicant to indigo. The invention is particularly useful in dyeing textiles from indican by simple light exposure, thereby providing a greener alternative to current industrial processes for colored fabrics and other products.
Owner:DANMARKS TEKNISKE UNIV

Preparation method of indophenol derivative

The invention discloses a preparation method of an indophenol derivative, and belongs to the technical field of preparation of blue indophenol dye compounds. Ni / TiO2 is creatively used as a photocatalyst, sodium chloride is used as a chlorine source, chlorination of a phenol compound is completed, reductive amination of a nitrophenol compound is completed through photocatalysis of CdS quantum dots, and the indophenol derivative is obtained. The KF / Al2O3 solid base with better cycle performance is subsequently used for catalyzing the reaction to successfully prepare the indophenol derivative; the synthetic route and process are simple, the conditions are mild, the high-yield and high-purity product is obtained while the preparation cost is reduced, and better reaction advantages and economic advantages are shown.
Owner:ZHEJIANG SCI-TECH UNIV +2

Electrochemical detection of monochloramine and / or ammonia

PendingCN121844201ATesting organic contamination in waterMaterial electrochemical variablesChloramineDifferential pulse voltammetry
An apparatus and method for determining the presence or amount of monochloramine and / or ammonia. The devices and methods utilize an electrochemical sensor that includes a working electrode, a reference electrode, and a counter electrode. The working electrode is coated with a formulation specifically for the analysis of monochloramine and / or ammonia comprising reagents associated with the Berthelot reaction to produce an indophenol product for electrochemical detection by voltammetry, in particular differential pulse voltammetry.
Owner:PALINTEST