24 results about "Phenylpropanoic acid" patented technology

The invention discloses a cistanche deserticola extract for improving bone mineral density, the total content of echinacoside and verbascoside in the cistanche deserticola extract is greater than 25wt%, and the cistanche deserticola extract is obtained by adding distilled water into cistanche tubulosa coarse powder for extraction, filtration, filtrate centrifugation, concentration, extraction, concentration and impurity removal, dilution, after-treatment, concentration and drying. The total content of echinacoside and verbascoside in the cistanche deserticola extract for improving the bone mineral density is 25-30 wt%, and the cistanche deserticola extract is rich in shikimic acid, phenylpropionic acid and alkaloid components, so that the cistanche deserticola extract can stably play a role in improving the bone mineral density.

The disclosure relates to oral care compositions comprising guanidine in free or orally acceptable salt form, a cationic quaternary ammonium compound (e.g., a pyridinium compound) (e.g., cetyl pyridinium chloride (CPC)), a fluoride source, and optionally a zinc source (e.g., zinc lactate or zinc citrate and zinc oxide) as well as to methods of using and of making these compositions. 20 25 20 43 72 12 J un 2 02 5 2 0 2 5 2 0 4 3 7 2 1 2 J u n 2 0 2 5 A B S T R A C T T h e d i s c l o s u r e r e l a t e s t o o r a l c a r e c o m p o s i t i o n s c o m p r i s i n g g u a n i d i n e i n f r e e o r o r a l l y a c c e p t a b l e s a l t f o r m , a c a t i o n i c q u a t e r n a r y a m m o n i u m c o m p o u n d ( e . g . , a p y r i d i n i u m c o m p o u n d ) ( e . g . , c e t y l p y r i d i n i u m c h l o r i d e ( C P C ) ) , a f l u o r i d e s o u r c e , a n d o p t i o n a l l y a z i n c s o u r c e ( e . g . , z i n c l a c t a t e o r z i n c c i t r a t e a n d z i n c o x i d e ) a s w e l l a s t o m e t h o d s o f u s i n g a n d o f m a k i n g t h e s e c o m p o s i t i o n s . 2 0 2 5 2 0 4 3 7 2 1 2 J u n 2 0 2 5

The present invention provides a phenylpropionic acid derivative, a preparation method, an antioxidant, and applications thereof, belonging to the fields of medicine, health, and the food industry. The phenylpropionic acid derivative is ethane-1,2-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)-propanoate). The present invention provides a new use for a phenylpropionic acid derivative. In vitro tests have confirmed that the phenylpropionic acid derivative provided by the present invention has good in vitro antioxidant activity and can be used as an active ingredient in an antioxidant, thus having a wide range of applications.

The present disclosure relates to a method for synthesizing a substituted phenylpropionic acid derivative. Specifically, the present disclosure relates to a method for preparing a compound as represented by formula I or a pharmaceutically acceptable salt thereof, which method exhibits a good yield.

The present application provides a compound as shown in the following formula I-1, a tautomer thereof or a pharmaceutically acceptable salt thereof, and application thereof as a GPR40 agonist.

The invention discloses application of phenylpropionic acid as a PPAR-gamma agonist in preparation of a product for preventing, relieving and / or treating enteritis, relates to the technical field of medicines, and solves the problems that the existing medicines are poor in curative effect and do not have dual effects of preventing and relieving enteritis at the same time. Phenylpropionic acid is used as a PPAR-gamma agonist, can reduce infiltration of inflammatory cells into intestinal tissues by activating PPAR-gamma receptors and inhibiting expression of adhesion molecules, and can also regulate functions of immune cells, reduce release of inflammatory mediators, remarkably reduce generation of proinflammatory cytokines and effectively relieve intestinal inflammatory response, so that the intestinal inflammatory response is reduced, and the intestinal inflammatory response is reduced. Therefore, immune-mediated intestinal injury is relieved, immune response is adjusted, and the anti-inflammatory effect is remarkable; by inhibiting the expression of a fibrosis promoting factor, the process of intestinal fibrosis is slowed down or reversed, and complications such as intestinal stenosis are prevented.

The present application relates to a method for preparing a thermoplastic molding composition based on an ABS copolymer, in which two or more compounds selected from the group consisting of A2: octadecyl 3-(3, 5-di-tert-butyl-4-hydroxyphenyl) propionate; a3: phenylpropionic acid, 3, 5-bis (1, 1-dimethylethyl)-4-hydroxy-, 1, 1 '-(thiodi-2, 1-ethylidene) ester, and A5: 4, 5-bis (1, 1-dimethylethyl)-4-hydroxy-, 1, 1'-(thiodi-2, 1-ethylidene) ester; and A4: a phenolic stabilizer A of 2, 4, 6-tri (3 ', 5'-di-tert-butyl-4 '-hydroxybenzyl) mesitylene, and a thio-co-stabilizer B. The invention further discloses a preparation method of the stabilizer. The ABS molding composition obtained by the method provided by the invention has good color stability.

The invention relates to the technical field of chinlon, in particular to a plant-source composite anti-ultraviolet functional chinlon filament and a preparation method thereof, and the plant-source composite anti-ultraviolet functional chinlon filament comprises the following raw materials: nylon 6, a functionalized lignin compound, tetra [beta-(3, 5-di-tert-butyl-4-hydroxyphenylpropionic acid) propyl] pentaerythritol ester and polyvinylpyrrolidone. According to the invention, furan groups are introduced into the lignin, so that the polar structure of the lignin can be effectively adjusted, the dispersion stability of the lignin in an organic phase system is improved, the lignin and polyamide molecules can form hydrogen bonds and pi-pi interaction, the interface bonding force and compatibility are remarkably enhanced, and the spinning defect caused by agglomeration of traditional lignin is avoided; the conjugated double bond in the furan ring and the aromatic skeleton of the lignin have a synergistic effect, so that ultraviolet radiation energy can be shielded, and non-radiation dissipation can be realized, thereby inhibiting the photooxidation fracture of the chinlon molecular chain and improving the ultraviolet aging resistance of the filament.

The application discloses application of a phenylpropionic acid compound in detection of monosaccharide composition of traditional Chinese medicine polysaccharide. The phenylpropionic acid compound has a structure as shown in formula (I). The application provides a new application of the phenylpropionic acid compound, and preliminary realization of quality control research on traditional Chinese medicine preknowing polysaccharide. Compared with a method for detecting monosaccharide composition of traditional Chinese medicine polysaccharide by using 1-phenyl-3-methyl-5-pyrazolone as a pre-column derivatization reagent, the application has the following advantages: 1. Derivatization of aldehyde sugar and ketose can be simultaneously realized; 2. The reaction temperature is more moderate, and the safety of the reaction is greatly improved; 3. The detection wavelength of HPLC-UV is improved from 245 nm to 274 nm, interference is reduced, and sensitivity is improved; and 4. The pre-column derivatization reagent is low in cost and easy to obtain.

The present application relates to a salt-tolerant microorganism Jejubacter sp. and its application, and belongs to the technical field of microorganisms. The Jejubacter sp. DT01 has a preservation number of CGMCC No. 26777. The Jejubacter sp. DT01 can grow normally under the conditions of high salt concentration (0-150 g / L) and high phenolic compound concentration (0-1000 mg / L), and has substrate diversity. In addition to the ordinary carbon sources such as glucose, fructose and the like which can be directly utilized, the Jejubacter sp. DT01 can not only decompose phenolic compounds such as m-hydroxyphenylpropionic acid, phenylpropionic acid, cinnamic acid, ferulic acid, benzoic acid and p-hydroxybenzoic acid, but also can utilize the above-mentioned phenolic compounds as the sole carbon source for growth.

This application relates to the use of hydroxyphenylpropanoate compounds of formula (I), (II), (III), (IV), or (V), or pharmaceutically acceptable salts, solvates, and / or ester prodrugs thereof, compositions comprising the same, and their use in, for example, cancer immunotherapy, for increasing antitumor immunity. More particularly, this application relates to compounds useful in the treatment of diseases, disorders, or conditions that can be treated by increasing intracellular antitumor immunity, such as cancer.

The invention belongs to the technical field of microbial fermentation, and particularly relates to a novel Pichia manshurica strain as well as a microbial agent and application thereof. In order to develop more pichia pastoris new strains and enrich microbial resources in fermented food, a pichia pastoris new strain 2J17 is separated, screened and identified from Maotai-flavor fermented grains, and the preservation number is CGMCC (China General Microbiological Culture Collection Center) No.39013. The strain not only can grow under high acidity, but also can generate a plurality of volatile aroma compounds, such as ethyl phenylpropionate, ethyl caprylate, isopropyl phenylpropionate, 2-methylbutyric acid-2-phenethyl ester, amyl-gamma-butyrolactone and the like. Therefore, when the strain is applied to fermented food, the flavor of the product can be more prominent, the flower and fruit fragrance and the nut fragrance can be provided at the same time, and the strain has important practical significance for improving the flavor of the fermented food, especially white spirit in production.

This invention discloses an antibacterial spinning oil suitable for acetate fibers used in cigarette filters, comprising an emulsifier, mineral oil, water, and an antibacterial agent. Before phase inversion, it is a transparent water-in-oil liquid; after phase inversion, it becomes a white oil-in-water emulsion. Phase inversion occurs in water or water containing the antibacterial agent. The mass ratio of the spinning oil to the water used for phase inversion or water containing the antibacterial agent before phase inversion is (1–49):(99–51). The antibacterial agent is a commercially available water-soluble antibacterial agent, selected from one or more of the following: 4-chloro-3-cresol, dichlorophenoxychlorophenol, bromochlorobisphenol, benzyl chloroethylammonium, benzalkonium chloride, dodecyl dimethyl ethylphenoxyethyl ammonium bromide, guanidine and guanidine polymers, quaternary ammonium salts, silver ions, copper ions, sodium phenylpropionate, nifedipine, dimethyl fumarate, sorbic acid, and dehydroacetic acid. The concentration of the antibacterial agent in water is 0.1 wt%–100 wt%.

This invention discloses a method for preparing a high-temperature resistant modified nylon 66 composite fiber material, relating to the field of nylon technology. The method includes the steps of preparing a composite reinforcing antioxidant component, preparing modified nano-silica, and obtaining the composite fiber material. The raw materials used to prepare the composite reinforcing antioxidant component include maleic anhydride-grafted polyolefin elastomer, 1,6-hexanediamine, processing stabilizer, 3,5-di-tert-butyl-4-hydroxyphenylpropionic acid, and p-toluenesulfonic acid. The raw materials used to prepare the modified nano-silica include nano-silica and a composite silane coupling agent. The raw materials used to obtain the composite fiber material include nylon 66 resin, the composite reinforcing antioxidant component, modified nano-silica, pentaerythritol stearate, epoxy resin, and a composite antioxidant additive. The nylon 66 composite fiber material prepared by this invention exhibits strong high-temperature resistance, excellent mechanical properties, and superior aging resistance.

The invention discloses a method for preparing a dihydrofuran-containing compound by using alpha-halogenated ester, which comprises the following steps of: adding 2-chloro-3-oxo-3-methyl phenylpropionate, 1, 1-disubstituted ethylene, N-methylindole, alkali and lewis acid into an organic solvent, reacting at room temperature under the irradiation of blue light, and then performing chromatography to obtain the dihydrofuran-containing compound. According to the method, methyl 2-chloro-3-oxo-3-phenylpropionate, 1, 1-disubstituted ethylene and N-methylindole are used as reactants, and the dihydrofuran-containing compound is obtained through one-step reaction under room-temperature blue light irradiation. The synthesis method has the advantages of high efficiency, simple conditions, high yield and environmental friendliness, and the target molecule has important application value in the fields of medicines and pesticides.

The present disclosure provides an additive for a spunbond nonwoven geotextile and a geotextile. The additive for a spunbond nonwoven geotextile includes titanium dioxide, tris(2,4- di-tert-butylphenyl)phosphite, tetrakis (3,5-di-tert-butyl-4-hydroxy) phenylpropanoic acid pentaerythritol ester, N,N'-ethylenebis(stearamide), zinc stearate, and hard acid ester. The additive can be added during a process of preparing a geotextile with polyethylene terephthalate. The additive can effectively improve the aging resistance of a light-weight geotextile fabric. When the existing geotextiles are used in a construction process, it is necessary to take activity-maintaining measures such as covering and light avoiding. When used outdoors, the geotextile prepared by the present disclosure does not require light-avoiding protection measures, which saves a lot of manpower, materials, and financial resources. 20 24 22 01 08 26 S ep 2 02 4 A B S T R A C T T h e p r e s e n t d i s c l o s u r e p r o v i d e s a n a d d i t i v e f o r a s p u n b o n d n o n w o v e n g e o t e x t i l e a n d a g e o t e x t i l e . T h e a d d i t i v e f o r a s p u n b o n d n o n w o v e n g e o t e x t i l e i n c l u d e s t i t a n i u m d i o x i d e , t r i s ( 2 , 4 - S e p 2 0 2 4 2 2 0 1 0 8 2 6 2 0 2 4 d i - t e r t - b u t y l p h e n y l ) p h o s p h i t e , t e t r a k i s ( 3 , 5 - d i - t e r t - b u t y l - 4 - h y d r o x y ) p h e n y l p r o p a n o i c a c i d p e n t a e r y t h r i t o l e s t e r , N , N ' - e t h y l e n e b i s ( s t e a r a m i d e ) , z i n c s t e a r a t e , a n d h a r d a c i d e s t e r . T h e a d d i t i v e c a n b e a d d e d d u r i n g a p r o c e s s o f p r e p a r i n g a g e o t e x t i l e w i t h p o l y e t h y l e n e t e r e p h t h a l a t e . T h e a d d i t i v e c a n e f f e c t i v e l y i m p r o v e t h e a g i n g r e s i s t a n c e o f a l i g h t - w e i g h t g e o t e x t i l e f a b r i c . W h e n t h e e x i s t i n g g e o t e x t i l e s a r e u s e d i n a c o n s t r u c t i o n p r o c e s s , i t i s n e c e s s a r y t o t a k e a c t i v i t y - m a i n t a i n i n g m e a s u r e s s u c h a s c o v e r i n g a n d l i g h t a v o i d i n g . W h e n u s e d o u t d o o r s , t h e g e o t e x t i l e p r e p a r e d b y t h e p r e s e n t d i s c l o s u r e d o e s n o t r e q u i r e l i g h t - a v o i d i n g p r o t e c t i o n m e a s u r e s , w h i c h s a v e s a l o t o f m a n p o w e r , m a t e r i a l s , a n d f i n a n c i a l r e s o u r c e s . A B S T R A C T S e p 2 0 2 4 2 2 0 1 0 8 2 6 2 0 2 4

The invention belongs to the technical field of binders for lithium supplementation, and discloses a composite binder for a lithium supplementation agent, a preparation method of the composite binder and a lithium ion battery, the composite binder for the lithium supplementation agent comprises a solvent, polyvinylidene fluoride and an antioxidant additive, and the antioxidant additive is selected from tetra (3, 4-dichlorophenyl)-1, 2, 3, 4-tetrakis (3, 4-dichlorophenyl)-1, 2, 3, 4-tetrakis (3, 4-dichlorophenyl)-1, 2, the preparation method comprises the following steps: adding 2, 5-di-tert-butyl-4-hydroxy) phenylpropionic acid pentaerythritol ester, beta-(3, 5-di-tert-butyl-4-hydroxy phenyl) n-octadecanol propionate, 2, 6-di-tert-butyl-4-methylphenol, 4-[(4, 6-dioctylsulfanyl-1, 3, 5-triazine-2-yl) amino]-2, 6-di-tert-butylphenol, 3-(3, 5-di-tert-butyl-4-hydroxy phenyl)-N '-[3-(3, 5-di-tert-butyl-4-hydroxy phenyl)-1, 3, 5-triazine-2-yl) amino]-2, 6-di-tert-butylphenol, 4-(4, 6-dioctyl sulfenyl-1, 3, 5- the compound is selected from at least one of 2, 5-di-tert-butyl-4-hydroxyphenyl) propionyl] propionyl hydrazine. The anti-oxidation additive can absorb active oxygen generated by the lithium supplement agent and is combined with the active oxygen to inhibit side reaction caused by the active oxygen, so that the formation gas production rate of the lithium supplement battery is effectively reduced, and the problem of high-temperature circulation or storage gas production of the lithium supplement battery is solved.

The invention discloses an isobutylphenylpropionic acid suspension drop, which is prepared from the following components in percentage by weight: 4 percent of isobutylphenylpropionic acid, 1.18 to 1.66 percent of xanthan gum 1 and xanthan gum 2, 0 to 0.075 percent of polysorbate 80, 0.18 percent of anhydrous citric acid, 0.2 percent of sodium benzoate, 30 percent of cane sugar, 10 percent of glycerol, 0.04 percent of essence and 53.845 to 54.4 percent of water. The D90 of the xanthan gum 1 is 10-40 [mu] m, the D90 of the xanthan gum 2 is 150-220 [mu] m, and the dosage ratio of the xanthan gum 1 to the xanthan gum 2 is (1.5-3.5): 1. Two xanthan gum with different particle sizes are compounded to serve as a thickening agent and a suspending aid to be prepared into the isobutylphenylpropionic acid suspension drop together with the active component isobutylphenylpropionic acid and other auxiliary materials, and the isobutylphenylpropionic acid suspension drop is stable in performance and better in state.

The application discloses a kind of optically active capsaicin molecules and its synthesis method and application.The optically active capsaicin molecules are (R)-N-(4-hydroxy-3-methoxybenzyl)-2-phenylpropanamide and (S)-N-(4-hydroxy-3-methoxybenzyl)-2-phenylpropanamide, which are prepared by amidation reaction of (R)-2-phenylpropanoic acid or (S)-2-phenylpropanoic acid with 4-(aminomethyl)-2-methoxyphenol at room temperature.The optically active capsaicin molecules have the characteristics of activating TRPV1, and are expected to be applied in the fields of drug research and pharmaceutical engineering.